1 of Table 7 Synthesis Table -: J-tip Practice Area: Drugs and Devices for Needlesticks/Procedures: J-Tip Topic J-Tip – a needleless injection system Citation Jimenez, N, Bradford, H, Seidel, KD, Sousa, M & Lynn AM A comparison of a needle-free injection system for local anesthesia versus EMLA for intravenous catheter insertion in the pediatric patient Anesth Analg 2006;102:411-4 Sample 116 Children 7-19 yrs RCT Key Findings More time from application to IV start with EMLA J-Tip had lower pain scores Both treatment groups had similar outcomes with success on first attempt. J-Tip – decrease vasoconstriction. EMLA not always on for 60 mins. (carbon dioxide gas cartridge drives plunger down the barrel of the syringe, expelling medication through a micro-orifice. Penetrates the skin surface and subQ tissue to a depth of 5-8 mm in 0.2s 84% reported no pain with J-Tip Compared with 64% with EMLA J-Tip – a needleless injection system Spanos, S, Booth, R, Koenigh et al Jet Injection of 1% Buffered Lidocaine versus Topical ELA-Max for Anesthesia Before peripheral Intravenous Catheterization in Children Pediatric Emergency Care 2008, 24(8) : 511-515 75 Children 8-15 yrs 30 minute ELA-Max J-tip 1% Lidocaine Pain with j-tip Pain with IV start Video-taped J-Tip less pain CRT Nurses who started IV- reported less pain in the J-tip grop Blinded observers scores for pain were less for J-tip Comments Pediatric patients have thicker subcutaneous tissue-deeper penetration of local anes Ref: Fine, B found that children younger than 7 seemed more disturbed by j-Tip Fast, absence of vasoconstriction J-Tip is a needless Food and Drug Adm injection system. J-Tip app with 1% buffered lido is not painful and had better anesthetic effect compared with EMLA Cost = ? Anesthesia in 5 minutes with j-tip No follow-up for complications with Jtip ( ? can scar) 2 of Table 7 J-Tip – a needleless injection system Cooper, JA, Bromley, LM, Baranowski, AP, & Barker SGE Evaluation of a needle-free injection system for local anaesthesia prior to venous cannulation Anaesthesia 200 55: 247-250 UK study 72 patients Adults over 18 yrs Prior to anesthesia J-tip or with a 25 G needle/syring Pain of treatment and pain of starting IV Less pain with J-tip delivery than needles but more pain with cannulation No difference in number of failed cannulations- but clinicians felt it was hard with lidocaine. RCT J-Tip – a needleless injection system Lysakowski, C, Dumont, L, Tramer, MR & Tassonyi, E A needle-free jet-injection system with lidocaine for peripheral intravenous cannula insertion: a randomized controlled trial with cost-effectiveness analysis. Anesthesia & Analgesia 2003: 96: 215-219 Swiss study 14-88yrs 4 groups; No treatmentsimulated sound Jet with saline Jet with 1% Jet with 2% 400 patients RCT Pt received midazolam orally prior to procedure Jet with lidocaine decreased pain. 2% reduced pain scores by 50% 1/5 of patients reported moderate pain from the jet delivery Device failure in 1/10 of application J-tip gives wide distribution Difficult delivery in thin patients with less subQ tissue. Original use was for insultin-administered in abdomen or thigh which has more subQ tissue than hard or hand. J-Tip 1.80 pounds and 2 ml syringewas 0.01 pounds Estimated cost for lidocaine jet was $4.1 $4.2. Incremental; costeffectiveness ration(ICER) was $10$11 for