Your high maintenance cosmetic patient wants you to use the best suture for the prettiest wound. (Yael Shapira) PRS 1996;98:814 PRS 2001;107:38 The most common complications of wounds in plastic surgery are: 1. tissue reactivity – Significant inflammation reduces the resistance to infection and delays the onset of wound healing 2. infection 3. dehiscence in order to achieve good healing with best scarring one should attempt to avoid these complications. Factors that affect wound healing process and may predispose or protect from these complications: 1. Patient factors - age & sex 2. Patient comorbidities - e.g. diabetes mellitus, vasculopathies, steroid use, connective tissue diseases 4. Wound factors – site & length 5. Suture material – type of suture (absorbable Vs. nonabsorbable, , mono Vs. multifilament, synthetic Vs. natural), caliber of the suture 6. Suture technique 7. surgeon experience Of all these factors, only the choice of suture and suturing technique is in the hands of the surgeon (notwithstanding experience…) . The considerations when choosing a suture material: Absorbable Vs. non-absorbable: absorbable sutures do not have to be removed (advantage in children) but lose their strength with time, sometimes in an unpredictable manner (e.g. gut) Natural Vs. synthetic: natural sutures cause inflammatory tissue reaction (absorbed by proteolysis) while synthetic sutures are absorbed by hydrolysis and generally cause less tissue reactivity. Monofilament Vs. multifilament: multi filament/braided sutures are easier to handle, but can sometimes cause tissue drag, even occasionally sawing through tissue. In addition, the spaces between the filaments can harbor bacteria. Monofilaments tend to have significant memory and can be difficult to handle. Suture caliber: the smaller the suture the weaker its tensile strength is (the more it tends to tear). conclusions of the 2001 article “suture material and other factors associated with tissue reactivity, infection, and wound dehiscence among plastic surgery outpatients” PRS 2001;107:38: a multi variant analysis of a 1000 plastic surgery outpatients comparing the factors mentioned above reached the following results: age - it has been shown that old age predisposes to tissue reactivity and infection, while younger ages (25>) predispose to dehiscence, perhaps due to higher levels of physical activity. Sex - male sex has a higher risk of tissue reactivity in two layer sutures and dehiscence in one layer sutures Wound length – longer wounds are associated with higher rates of tissue reactivity ( in one layer sutures). Wound site – wounds in lower limbs are less prone to tissue reactivity, wounds on the back are prone to dehiscence. Suture material & technique – the type and caliber of sutures and suturing technique were not related to any clinically significant extent to short term postoperative complications. Surgeon experience – less experienced surgeons have a higher rate of dehiscence and tissue reactivity. Conclusions of the 1996 article “comparison of polydeoxanone and polyglactin 910 in intradermal repair” PRS 1996;98:814: A prospective clinical study that compared scars of 80 surgical sites sutured alternately with these two types of sutures. No statistically significant difference was found between the types of sutures regarding erythema, induration, scar spread and hypertrophic scarring 5 months and 1 year postoperatively. Properties of absorbable suture material Property Gut Polyglycolic Acid Polyglactin Polydioxanone Polytrimethylene Carbonate tradename - dexon vicryl PDS-II maxon monocryl Handling Fair Fair-good Good Poor Good Excellent filament multi Mono/multi multi mono mono mono Knot security Poor Fair-good Fair Poor Good Good Tensile strength Low proteolysis at 60-90 days, unpredicta ble High hydrolysis at 90-120 days High hydrolysis at 60-90 days Moderate hydrolysis at 180-210 days High hydrolysis at 180-210 days High Medium Low Low Low Coefficient of friction Poliglecaprone High hydrolysis at 90-120 days Memory Low Low Low High Low Low Tissue reactivity High Low-moderate Lowmoderate Low Low Low Absorption time (d) 30 90 90 210 180 28 Effective wound support (d) 8-9 21 21 60 60 20 Sutures in mucosal tissues, vessel ligation Buried sutures Buried sutures Buried sutures in wounds requiring longer dermal support Buried sutures in wounds requiring longer dermal support Buried sutures Low elasticity, clear or green Low elasticity, clear or violet Clear or violet Clear or green High elasticity, clear Uses Other Properties of non-absorbable suture material Silk Nylon, Monofilament Nylon, Multifilament Polyester Polypropylene tradename mersilk ethilon nurolon Mersilene/ ethibond prolene Handling Excellent Poor Fair-good Good Poor Good Knot security Excellent Poor Fair-good Good Poor Fair-good Tensile strength Low High High High Moderate High Coefficient of friction High Low High High Very Low Very Low Memory Low High Medium Medium High Low Tissue reactivity High Low Moderate Lowmoderate Low Low Sutures in mucosal tissues or conjunctive or intertriginous zones to elevate or retract tissues Percutaneous sutures, buried sutures if prolonged dermal support is needed Minimal use in dermatologic surgery Properties Uses Other Black Black, green, or clear Polybutester novafil Minimal use in dermatologic surgery Percutaneous sutures, buried sutures if prolonged dermal support is needed, running subcuticular closures Percutaneous sutures, running subcuticular closures Green or clear High plasticity, blue or clear High elasticity, blue or clear