TAG Mail 7th January 2015 TAG MEETINGS Nil TAG ACTIVITIES Wishing you all a Happy New year! WEBSITE UPDATE -The Lifesaving Drugs Register for Antivenoms has been updated: http://www.ciap.health.nsw.gov.au/nswtag/pages/life-saving-drugsregister.html REPORTS AND PUBLICATIONS - AUSTRALIA **AIHW - Staphylococcus aureus bacteraemia in Australian public hospitals 2013–14: Australian hospital statistics http://www.aihw.gov.au/publication-detail/?id=60129550044 - Cardiovascular disease, diabetes and chronic kidney disease: Australian facts: morbidity—hospital care http://www.aihw.gov.au/publication-detail/?id=60129550063 - Health expenditure Australia 2012–13: analysis by sector http://www.aihw.gov.au/publication-detail/?id=60129550083 **NPS-MedicineWise Antibiotics in infancy linked to childhood obesity http://www.nps.org.au/publications/health-professional/health-newsevidence/2014/infancy-antibiotics-obesity **NSW Health - 2014 Policy Directives & Guidelines -- Guidelines for the Management of Substance Use During Pregnancy Birth and the Postnatal Period -- Infants and Children: Management of Acute Gastroenteritis, Fourth Edition -- Principles for the Management of Tuberculosis in New South Wales http://www0.health.nsw.gov.au/policies/date/2014.asp - Building a sustainable health workforce for rural NSW http://www.health.nsw.gov.au/rural/Pages/building-sustainableworkforce.aspx **TGA Orphan drugs added Factor XI Concentrate (human coagulation factor XI) http://www.tga.gov.au/updates-list-designated-orphan-drugs REPORTS AND PUBLICATIONS – INTERNATIONAL **CADTH - Rapid responses -- Dexmedetomidine for Sedation in the ICU or PICU: A Review of CostEffectiveness and Guidelines -- Intravenous Administration of Medications in Home Care Settings: Clinical Evidence and Guidelines http://www.cadth.ca/en/products/rapid-response **FDA - FDA approvals: -- weight-management drug Saxenda (liraglutide [rDNA origin] injection) http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm427913. htm -- Opdivo (nivolumab) for advanced melanoma http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm427716. htm -- Rapivab (peramivir) to treat flu infection http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm427755. htm -- Lynparza (olaparib) to treat advanced ovarian cancer http://www.fda.gov/Drugs/NewsEvents/ucm130958.htm -- new antibacterial drug Zerbaxa (ceftolozane/tazobactam) http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm427534. htm **NICE - Evidence Update -- Hyperphosphataemia in chronic kidney disease, December 2014 http://arms.evidence.nhs.uk/resources/hub/1041123/attachment - Evidence summary: new medicine -- Hyperphosphataemia in adults with chronic kidney disease on dialysis: sucroferric oxyhydroxide [ESNM51] http://www.nice.org.uk/advice/esnm51 - Quality standards -- Antibiotics for neonatal infection [QS75] http://www.nice.org.uk/guidance/qs75 -- Acute kidney injury [QS76] http://www.nice.org.uk/guidance/qs76 MEDICATION SAFETY **ISMP Tragic error with neuromuscular blocker should prompt risk assessment by all hospitals http://www.ismp.org/newsletters/acutecare/showarticle.aspx?id=97 **MHRA Drug safety update, December 2014 includes: Ivabradine (Procoralan) in the symptomatic treatment of angina: risk of cardiac side effects—new advice to minimise risk | Isotretinoin (Roaccutane): reminder of possible risk of psychiatric disorders—warn patients and family; monitor patients for signs of depression | Hydroxyethyl starch intravenous infusions to be used only in patients with acute blood loss and when crystalloids alone are not sufficient http://www.mhra.gov.uk/Safetyinformation/DrugSafetyUpdate/index.htm PAPERS OF INTEREST **Am J Health-Syst Pharm - Effect of computerized prescriber order entry on pharmacy: Experience of one health system http://www.ajhp.org/content/72/2/133.abstract **Ann Intern Med - Valganciclovir for the Prevention of Complications of Late Cytomegalovirus Infection After Allogeneic Hematopoietic Cell Transplantation: A Randomized TrialLate CMV Prevention After HCT http://annals.org/article.aspx?articleid=2088543 - Comparative Effectiveness of Pharmacologic Interventions for Knee Osteoarthritis: A Systematic Review and Network Meta-analysisPharmacologic Interventions for Knee OA http://annals.org/article.aspx?articleid=2088548 - Effects of Blood Pressure Reduction in Mild Hypertension: A Systematic Review and Meta-analysis http://annals.org/article.aspx?articleid=2085847 **BMJ Qual Saf Adverse events in patients with return emergency department visits http://qualitysafety.bmj.com/content/early/2014/12/24/bmjqs-2014003194.short?g=w_qs_ahead_tab **Cochrane Collaboration - Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006897.pub3/abstract; jsessionid=B89364C93CAAF59E71F14C84F72F37C4.f04t01 - Erythropoiesis-stimulating agents for anaemia in adults with chronic kidney disease: a network meta-analysis http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD010590.pub2/abstract **JAMA Intern Med - Secondary Prevention of Cardiovascular Disease With Vorapaxar: A New Era of 3-Drug Antiplatelet Therapy? http://archinte.jamanetwork.com/article.aspx?articleid=1921757 - Risk of Bleeding With Dabigatran in Atrial Fibrillation http://archinte.jamanetwork.com/article.aspx?articleid=1921753 - Medication Therapy Management Interventions in Outpatient Settings: A Systematic Review and Meta-analysis http://archinte.jamanetwork.com/article.aspx?articleid=1935933 **MJA Australia-wide point prevalence survey of the use and appropriateness of antimicrobial prescribing for children in hospital https://www.mja.com.au/journal/2014/201/11/australia-wide-pointprevalence-survey-use-and-appropriateness-antimicrobial **Pediatrics - Anaerobic Antimicrobial Therapy After Necrotizing Enterocolitis in VLBW Infants http://pediatrics.aappublications.org/content/135/1/e117.abstract - Antimicrobial Stewardship Programs in Freestanding Children’s Hospitals http://pediatrics.aappublications.org/content/135/1/33.abstract - Off-Label Prescribing in Pediatric Outpatients http://pediatrics.aappublications.org/content/135/1/49.abstract CONSULTATIONS **AHHA AHHA has now released (brief) surveys on the Pharmacy Competency Framework and invite “Individual pharmacists” and “Non-pharmacy health organisations and individuals” to "Shape the future of health" by 30 January 2015 https://ahha.asn.au/pharmacy-competency-framework-consultation OTHER NEWS Nil UPCOMING EVENTS (new additions in bold) **IIR 4th Annual eMedication Management Conference. 26-27 March, Sydney. Call for abstracts open http://www.informa.com.au/conferences/health-care-conference/electronicmedication-management **CADTH 2015 CADTH Symposium: What Does the Evidence Say? HTA to Support Policy and Practice. April 12 – 14, 2015, Saskatoon, Canada http://www.cadth.ca/en/events/cadth-2015-sympos **IHI/BMJ - International Forum on Quality and Safety in Healthcare: 21-24 April 2015, London http://internationalforum.bmj.com/ - International Forum on Quality and Safety in Healthcare: Asia. New Thinking, Shared Knowledge, Improved Outcomes. 28-30 September 2015, Hong Kong. Abstract submissions close 15 December 2014 http://internationalforumasia.bmj.com/