Saucon Valley School District Planned Course of Study Course Title Grade Level Content Area Length of Course Author(s) Advanced Placement Biology 11th and 12th Grades Science Semester Andrew Koch Course Description: AP Biology is an introductory college-level biology course. Students cultivate their understanding of biology through inquiry-based investigations as they explore the following topics: evolution, cellular processes (energy and communication, genetics, information transfer) as well as ecology, and interactions. The course is based on four Big Ideas, which encompass core scientific principles, theories, and processes that cut across traditional boundaries and provide a broad way of thinking about living organisms and biological systems. The following are the Big Ideas: The process of evolution explains the diversity and unity of life. Biological systems utilize free energy and molecular building blocks to grow, to reproduce, and to maintain dynamic homeostasis Living systems store, retrieve, transmit, and respond to information essential to life processes Biological systems interact, and these systems and their interactions possess complex properties Since AP Biology is an integrated curriculum each, standard, lesson, topic, laboratory investigation, and chapter in the text addresses each of the big ideas to varying degrees. Course Rationale: Students who take this curriculum framework will develop advanced inquiry and reasoning skills, such as designing a plan for collecting data, analyzing data, applying mathematical routines, and connecting concepts in and across domains. The result will be readiness for the study of advanced topics in subsequent college courses. Following the successful completion of AP Biology students will be eligible to sit for the AP Biology examination. Depending upon the score attained and the institution they will be attending following graduation the student may receive college credit. AP Biology Summer 2014 Page 1 of 57 Saucon Valley School District Planned Course of Study Page 3 Page 14 Page 15 Page 18 Page 20 Page 24 Page 25 Page 28 Page 32 Page 33 Page 35 Page 38 Page 39 Page 41 Page 44 Page 45 AP Biology Summer 2014 Table of Contents Curriculum Map AP Biology Laboratory Investigations Unit 1 – Biological Systems - Description, Essential Questions and Enduring Understandings; PA Science Standards; PA Core Literacy Standards Learning Objectives Essential Knowledge; Concept and Content Connections Resources for this Unit Unit 2 – Living Systems -Description, Essential Questions and Enduring Understandings; PA Science Standards; PA Core Literacy Standards for Science; Learning Objectives Essential Knowledge, Concept and Content Connections Resources for this Unit Unit 3 – Process of Evolution - Description, Essential Questions and Enduring Understandings ; PA Science Standards and PA Core Literacy Standards for Science; Learning Objectives Essential Knowledge; Concept and Content Connections Resources for this Unit Unit 4 – Biological Interactions – Description; Essential Questions and Enduring Understandings; PA Science Standards; PA Core Literacy Standards for Science; Learning Objectives Essential Knowledge; Concept and Content Connections Resources for this Unit Appendix A – Key Vocabulary by Chapter Page 2 of 57 Saucon Valley School District Planned Course of Study Curriculum Map (Semester Course) Quarter Topics covered during this time period 1 or 3 1. The themes of biology, an introduction to biology (1 block) a. Structural levels of biological organization and emergent properties b. Life’s processes c. Transfer and transformation of matter and energy d. Interactions within and between structural levels of biological organization e. The unifying theory of biology, evolution f. Classification of the diversity of life g. The tree of life h. The scientific method i. Experimental design j. Scientific theories and the philosophy of science k. Science as a communal endeavor 2. Cell communication (2 blocks) a. Evolution of cell signaling b. Cell signaling over short and long distances c. The stages of cell signaling d. Cell receptors in the plasma membrane e. Intracellular receptors f. Signal transduction pathways g. The role of protein phosphorylation and dephosphorylation h. Small molecules and ions as secondary messengers i. Nuclear and cytoplasmic responses to signaling pathways j. Regulation of responses to cell signaling k. Apoptosis and cell signaling pathways 3. The cell cycle (1 block) a. Cellular organization of genetic material b. Distribution of chromosomes during eukaryotic cell division c. Phases of the cell cycle d. Binary fission in bacteria e. The evolution of mitosis f. Control mechanisms of the cell cycle 4. Meiosis and sexual life cycles (1 Block) a. Inheritance of genes b. Comparing asexual and sexual reproduction c. Sets of chromosomes in human cells and their behavior d. Stages of meiosis e. Crossing over and synapsis f. The origins of genetic variation among offspring AP Biology Summer 2014 Page 3 of 57 Saucon Valley School District Planned Course of Study 5. Mendelian genetics (1 Block) a. Analyzing Mendel’s experiments and results b. The law of segregation c. The law of independent assortment d. Mathematical analysis of monohybrid crosses and application of the laws of probability e. Inheritance patterns not predicted by Mendelian genetics f. Application of Mendelian genetic analysis to one and multiple genes g. Environmental influence on phenotype h. Pedigree analysis i. Recessively inherited disorders j. Dominantly inherited disorders k. Multifactorial disorders 6. The chromosomal basis of inheritance (1 Block) a. Morgan’s experiments with fruit flies b. Correlating behavior of a gene’s alleles with the behavior of chromosome pairs c. The chromosomal basis of sex d. Inheritance of X-linked genes e. X inactivation in female mammals f. Genetic recombination and gene linkage g. Creating gene linkage maps h. Alterations of chromosome number and structure i. Human disorders due to chromosomal alterations 7. The molecular basis of inheritance (1 Block) a. Key experiments in the discovery of DNA as the molecule of heredity and its structure b. Base pairing in DNA and RNA c. Semiconservative DNA replication d. Proofreading and repair of altered DNA nucleotides e. The evolutionary significance of altered DNA nucleotides f. DNA replication in linear and circular chromosomes g. DNA packing 8. Gene expression (1 Block) a. The basic principles of transcription and translation b. The genetic code c. The molecular components of transcription d. Synthesis of an mRNA transcript e. Post-transcriptional controls in eukaryotic organisms f. Molecular components of translation g. Construction of a polypeptide h. Completing and targeting the functional protein AP Biology Summer 2014 Page 4 of 57 Saucon Valley School District Planned Course of Study i. Making multiple polypeptides in bacteria and eukaryotes j. Types of small-scale mutations k. New mutations and mutagens 9. Regulation of gene expression (1 Block) a. Bacterial control of gene expression b. Types of negative gene regulation in bacteria, inducible and repressible operons c. Positive gene regulation of the operon d. Differential gene expression in eukaryotes e. Regulation of chromatin structure in eukaryotes f. Regulation of transcription initiation in eukaryotes g. Mechanisms of post-transcriptional regulation in eukaryotes h. Effects on mRNA’s by microRNA’s and siRNA’s i. A genetic program for embryonic development j. Cytoplasmic determinants and inductive signals in cell differentiation k. Sequential regulation of gene expression during cellular differentiation l. The body plan genes 10. Viruses (1 Block) a. The discovery of viruses b. Viral structure c. General features of viral replication cycles d. Replication of phages e. Replication of animal viruses f. Evolution of viruses g. Viral diseases of animals h. Emerging viruses i. Viral diseases of plants 11. Genomes and their evolution (1 Block) a. Analyzing genome sequences b. Identifying protein-coding genes and understanding their functions c. Understanding genes and gene expression at the systems level d. Genome size e. Number of genes f. Gene density and noncoding DNA g. Transposable elements and related sequences in eukaryotes h. Alterations of chromosome structure i. Exon duplication and exon shuffling j. How transposable elements contribute to genome evolution 12. Descent with modification (1 Block) a. Scala Naturae and classification of species AP Biology Summer 2014 Page 5 of 57 Saucon Valley School District Planned Course of Study b. Ideas about change over time c. Lamarck’s hypothesis of descent with modification d. Darwin’s research e. The origin of species f. Direct observations of evolutionary change g. Homology h. The fossil record i. Biogeography 13. The evolution of populations (1 Block) a. Genetic variation is required for evolution b. Sources of genetic variation c. Gene pools and allele frequencies d. Using the Hardy-Weinberg equation e. Natural selection f. Genetic drift g. Gene flow h. The key role of natural selection in adaptive evolution i. Sexual selection j. Directional selection, balancing selection and stabilizing selection k. Limitations of natural selection 14. The origin of species (1 Block) a. The biological species concept b. Other species definitions c. Allopatric and sympatric speciation d. Patterns within hybrid zones e. Hybrid zones over time f. The time course of speciation g. The genetics of speciation h. From speciation to macroevolution 15. The history of life on Earth (1 Block) a. Synthesis of organic compounds on early Earth b. Abiotic synthesis of macromolecules c. Protocells d. Self-replicating RNA e. The fossil record f. Fossil dating methods g. The origin of new groups of organisms h. The first single-celled organisms i. The origin of multicellularity j. The colonization of land k. Plate techtonics and patterns of fossil distribution l. Mass extinctions set the stage for rapid evolution and adaptive AP Biology Summer 2014 Page 6 of 57 Saucon Valley School District Planned Course of Study radiation m. The effects of developmental genes in evolution n. The evolution of development o. Why evolution is not goal oriented 16. Phylogeny and the tree of life (2 Blocks) a. Binomial nomenclature b. Hierarchical classification c. The connections between classification and phylogeny d. Applying phylogenies e. Morphological and molecular homologies f. The difference between homology and analogy g. Evaluating molecular homologies h. Cladistics i. Phylogenic trees with proportional branch lengths j. Maximum parsimony and maximum likelihood k. Phylogenic trees as hypotheses l. Documentation of evolutionary history of organisms in their genomes m. Gene duplication and gene families n. Genome evolution o. Molecular clocks p. The development of domains from kingdoms q. The role of horizontal gene transfer 17. The origin and evolution of vertebrates (1 Block) a. The characteristics of chordates b. Early chordate evolution c. The characteristics of vertebrates d. Early vertebrate evolution e. The origins of bones and teeth f. The characteristics of gnathostomes g. Fossil gnathostomes h. The chondricthyans i. Ray-finned fishes and lobe-fins j. Characteristics of tetrapods k. The origin of tetrapods l. Characteristics of a m. Amphibians n. Characteristics of amniotes o. Early amniotes p. Reptiles q. Characteristics of mammals r. Early evolution of mammals s. Monotremes AP Biology Summer 2014 Page 7 of 57 Saucon Valley School District Planned Course of Study 2 or 4 AP Biology Summer 2014 t. Marsupials u. Eutherians v. Characteristics of humans w. The earliest Hominins x. Australopiths y. Bipedalism z. Development of tool use aa. Early Homo bb. Neanderthals cc. Homo sapiens 18. Plant structure, growth and development (1 Block) a. The three basic plant organs: roots, stems and leaves b. Dermal, vascular, and ground tissue systems c. Meristem generation of new cells for primary and secondary growth d. Common types of plant cells e. Primary growth of roots f. Primary growth of shoots g. The vascular cambrium and secondary vascular tissue h. The cork cambrium and production of periderm i. The evolution of secondary growth j. Model organisms used to revolutionize the study of plants k. Plant growth: cell division and cell expansion l. Gene expression and the control of cell differentiation m. Shifts in development: phase changes n. Genetic control of flowering 19. Resource acquisition and transport in vascular plants (1 Block) a. Shoot architecture and light capture b. Root architecture and acquisition of water and minerals c. The apoplast and symplast: transport continuums d. Short-distance transport of solutes across plasma membranes e. Short-distance transport of water across plasma membranes f. Long-distance transport: the role of bulk flow g. Absorption of water and minerals by root cells h. Transport of water and minerals into the xylem i. The role of stomata in regulating water loss j. Mechanisms of stomata opening and closing k. Stimuli for stomatal opening and closing l. Effects of transpiration on wilting and leaf temperature m. Adaptations that reduce evaporative water loss n. Movement from sugar sources to sugar sinks o. Bulk flow by positive pressure: the mechanism of translocation in angiosperms Page 8 of 57 Saucon Valley School District Planned Course of Study p. Changes in plasmodesmata number and pore size q. The role of phloem in dissemination of information r. Electrical signaling in the phloem 20. Angiosperm reproduction and biotechnology (1 Block) a. Flower structure and function b. The angiosperm life cycle c. Methods of pollination d. From a seed to flowering plant e. Fruit structure and function f. Mechanisms of asexual reproduction g. Advantages and disadvantages of asexual and sexual reproduction h. Mechanisms that prevent self-fertilization i. Totipotency, vegetative reproduction, and tissue culture j. Plant breeding k. Plant biotechnology and genetic engineering l. The debate over plant biotechnology 21. Plant responses to internal and external signals (1 Block) a. Reception, transduction, and response in signal transduction pathways b. Plant hormone role in coordinating growth, development, and responses to stimuli c. Blue-light photoreceptors d. Phytochrome photoreceptors e. Biological clocks and Circadian rhythms f. The effect of light on the biological clock g. Photoperiodism and responses to seasons h. Plant response to gravity i. Plant response to mechanical stimuli j. Plant responses to environmental stressors k. Plant defenses against pathogens and herbivores 22. Animal form and function (1 Block) a. Evolution of animal size and shape b. Exchange with the environment c. Hierarchical organization of body plans d. Coordination and control e. Feedback regulation of animal internal environments (homeostasis) f. Homeostatic processes for thermoregulation g. Endothermy and ectothermy h. Variation in body temperature i. Balancing heat loss and gain j. Acclimatization in thermoregulation AP Biology Summer 2014 Page 9 of 57 Saucon Valley School District Planned Course of Study k. Physiological thermostats and fever l. Energy allocation and use m. Quantifying energy use n. Minimum metabolic rate and thermoregulation o. Influences on metabolic rate p. Torpor and energy conservation 23. Circulation and gas exchange (1 Block) a. Gastrovascular cavities b. Open and closed circulatory systems c. Organization of vertebrate circulatory systems d. Blood composition and function e. Partial pressure gradients in gas exchange 24. The immune system (2 Blocks) a. Innate immunity in invertebrates b. Innate immunity of vertebrates c. Evasion of innate immunity by pathogens d. Antigen recognition by B cells and antibodies e. Antigen recognition by T cells f. B cell and T cell development g. Helper T cells: a response to nearly all antigens h. Cytotoxic T cells: a response to infected cells i. B cells and antobodies: a response to extracellular pathogens j. Summary of humoral and cell-mediated immune responses k. Active and passive immunity l. Antibodies as tools m. Immune rejection n. Exaggerated, self-directed, and diminished immune responses o. Evolutionary adaptations of pathogens that underlie immune system avoidance 25. Osmoregulation and excretion (1 Block) a. Osmosis and osmolarity b. Osmoregulatory challenges and mechanisms c. Energetics of osmoregulation d. Transport epithelia in osmoregulation e. Forms of nitrogenous waste f. The influence of evolution and environment on nitrogenous wastes g. Excretory processes h. Survey of excretory systems i. From blood filtrate to urine j. Solute gradients and water conservation k. Adaptations of the vertebrate kidney to diverse environments l. Homoeostatic regulation of the kidney AP Biology Summer 2014 Page 10 of 57 Saucon Valley School District Planned Course of Study 26. Hormones and the endocrine system (2 Blocks) a. Intercellular communication b. Chemical classes of local regulators and hormones c. Cellular response pathways d. Multiple effects of hormones e. Endocrine tissues and organs f. Simple hormone pathways g. Feedback regulation h. Coordination of endocrine and nervous systems i. Thyroid regulation: a hormone cascade pathway j. Hormonal regulation of growth k. Parathyroid hormone and vitamin D: control of blood calcium l. Adrenal hormones: response to stress m. Hormones and biological rhythms n. Evolution of hormone function 27. Neurons, synapses, and signaling (1 Block) a. Neuron structure and function b. Introduction to information processing c. Formation of a resting potential d. Modeling the resting potential e. Hyperpolarization and depolarization f. Graded potentials and action potentials g. Generation of action potentials h. Conduction of action potentials i. Generation of postsynaptic potentials j. Summation of postsynaptic potentials k. Modulating signaling at synapses l. Neurotransmitters 28. Nervous systems (1 Block) a. Glia b. Organization of the vertebrate nervous system c. The peripheral nervous system d. Arousal and sleep e. Biological clock regulation f. Emotions g. Functional imaging of the brain h. Information processing i. Language and speech j. Lateralization of cortical function k. Frontal lobe function l. Evolution of cognition in vertebrates m. Neuronal plasticity n. Memory and learning AP Biology Summer 2014 Page 11 of 57 Saucon Valley School District Planned Course of Study o. Long-term potential p. Schizophrenia q. Depression r. The brain’s reward system and drug addiction s. Alzheimer’s disease t. Parkinson’s disease 29. Sensory and motor mechanisms (1 Block) a. Sensory reception and transduction b. Transmission c. Perception d. Amplification and adaptation e. Types of sensory receptors f. Sensing of gravity and sound in invertebrates g. Hearing and equilibrium in mammals h. Hearing and equilibrium in other vertebrates i. Evolution of visual perception j. The vertebrate visual system k. Taste in mammals l. Smell in mammals m. Vertebrate skeletal muscle n. Other types of muscle o. Types of skeletal systems p. Types of locomotion 30. Animal behavior (1 Block) a. Fixed action patterns b. Migration c. Behavioral rhythms d. Animal signals and communication e. Experience and behavior f. Learning g. Evolution of foraging behavior h. Mating behavior and mate choice i. Genetic basis of behavior j. Genetic variation and the evolution of behavior k. Altruism l. Inclusive fitness m. Evolution and human culture 31. An introduction to ecology and the biosphere (1 Block) a. Global climate patterns b. Regional and local effects on climate c. Microclimate d. Global climate change e. Climate and terrestrial biomes AP Biology Summer 2014 Page 12 of 57 Saucon Valley School District Planned Course of Study f. General features of terrestrial biomes g. Disturbance and terrestrial biomes h. Zonation in acquatic biomes i. Dispersal and distribution of species j. Behavior and habitat selection k. Biotic and abiotic factors 32. Population ecology (2 Blocks) a. Density and dispersion of species b. Demographics c. Per capita rate of population increase d. Exponential growth rate of populations e. Logistic growth model f. The logistic model and real populations g. Evolution and life history diversity h. Population change and population density i. Mechanisms of density-dependent population regulation j. Population dynamics k. The global human population l. Global carrying capacity 33. Community ecology (1 Block) a. Competition b. Predation c. Herbivory d. Symbiosis e. Facilitation f. Species diversity g. Diversity and community stability h. Trophic structure i. Species with large impacts j. Bottom up and top-down controls k. Characterizing disturbance l. Ecological succession m. Human disturbance n. Latidudinal gradients o. Area effects p. Island equilibrium model q. Pathogens and community structure r. Community ecology and zoonotic diseases 34. Ecosystems and restoration ecology (1 Block) a. Law of conservation of energy b. Law of conservation of mass c. Energy, mass and trophic levels d. Ecosystem energy budgets AP Biology Summer 2014 Page 13 of 57 Saucon Valley School District Planned Course of Study e. f. g. h. i. j. k. l. Big Idea Evolution Cellular Processes: Energy and Communication Genetics and Information Transfer Interactions AP Biology Summer 2014 Primary production in aquatic ecosystems Primary production in terrestrial ecosystems Production efficiency Trophic efficiency and ecological pyramids Biogeochemical cycles Decomposition and nutrient cycling rates Bioremediation Biological augmentation Required Labs for AP Biology Laboratory Investigation 1. Artificial Selection (5 Blocks) 2. Mathematical Modeling (2 Blocks) 3. Comparing DNA Sequences (2 Blocks) 4. Diffusion and Osmosis (3 Blocks) 5. Photosynthesis (2 Blocks) 6. Cellular Respiration (2 Blocks) 7. Cell Division: Mitosis and Meiosis (3 Blocks) 8. Biotechnology: Bacterial Transformation (3 Blocks) 9. Biotechnology: Restriction Enzyme Analysis of DNA (2 Blocks) 10. Energy Dynamics (3 Blocks) 11. Transpiration (2 Blocks) 12. Fruit Fly Behavior (2 Blocks) 13. Enzyme Activity (2 Blocks) Page 14 of 57 Saucon Valley School District Planned Course of Study Unit Title Unit Description Essential Questions & Enduring Understandings Unit 1 – Biological Systems Biological systems utilize free energy and molecular building blocks to grow, to reproduce and to maintain dynamic homeostasis (Big Idea 2) 2.A: Growth, reproduction and maintenance of the organism of the living systems require free energy and matter. 2.B: Growth, reproduction and dynamic homeostasis require that cells create and maintain internal environments that are different from their external environments. 2.C: Organisms use feedback mechanisms to regulate growth and reproduction, and to maintain dynamic homeostasis. 2.D: Growth and dynamic homeostasis of a biological are influenced by changes in the system’s environment. 2.E: Many biological processes involved in growth, reproduction and dynamic homeostasis include temporal regulation and coordination. PA Science Standards 3.1.B.A1, Describe the common characteristics of life. Compare and contrast the cellular structures and degrees of complexity of prokaryotic and eukaryotic organisms. Explain that some structures in eukaryotic cells developed from prokaryotic cells (e.g., mitochondria, chloroplasts) 3.1.B.A2, Identify the initial reactants, final products, and general purposes of photosynthesis and cellular respiration. Explain the important role of ATP in cell metabolism. Describe the relationship between photosynthesis and cell respiration in photosynthetic organisms. Explain why many biological macromolecules such as ATP and lipids contain high-energy bonds. Explain the importance of enzymes as catalysts in cell reactions. Identify how factors such as pH and temperature may AP Biology Summer 2014 PA Core Literacy Standards for Science Reading in Science and Technical Subjects: CC.3.5.11-12.A, Cite specific textual evidence to support analysis of science and technical texts, attending to important distinctions the author makes and to any gaps or inconsistencies in the account. CC.3.5.11-12.B, Determine the central ideas or conclusions of a text; summarize complex concepts, processes, or information presented in a text by paraphrasing them in simpler but still accurate terms CC.3.5.11-12.C. Follow precisely a complex multistep procedure when carrying out experiments, taking measurements, or performing technical tasks; analyze the specific results based on explanations in texts. Page 15 of 57 Saucon Valley School District Planned Course of Study affect enzyme function. 3.1.B.A3, Explain how all organisms begin their life cycles as a single cell and that in multicellular organisms, successive generations of embryonic cells form by cell division. 3.1.B.A4, Summarize the stages of the cell cycle. Examine how interactions among the different molecules in the cell cause the distinct stages of the cell cycle which can also be influenced by other signaling molecules. Explain the role of mitosis in the formation of new cells and its importance in maintaining chromosome number during asexual reproduction. Compare and contrast a virus and a cell. Relate the stages of viral cycles to the cell cycle. 3.1.B.A5, Relate the structure of cell organelles to their function (energy capture and release, transport, waste removal, protein synthesis, movement, etc). Explain the role of water in cell metabolism. Explain how the cell membrane functions as a regulatory structure and protective barrier for the cell. Describe transport mechanisms across the plasma membrane. 3.1.B.A6, Explain how cells differentiate in multicellular organisms. 3.1.B.A7, Analyze the importance of carbon to the structure of biological macromolecules. Compare and contrast the functions and structures of proteins, lipids, carbohydrates, and nucleic acids. Explain the consequences of extreme changes in pH and temperature on cell proteins. 3.1.B.A8, Recognize that systems within cells and multicellular organisms interact to maintain homeostasis. Demonstrate the repeating patterns that occur in biological polymers. Describe how unique properties of water support life. 3.1.B.A9, Compare and contrast scientific AP Biology Summer 2014 CC.3.5.11-12.D, Determine the meaning of symbols, key terms, and other domainspecific words and phrases as they are used in a specific scientific or technical context relevant to grades 11–12 texts and topics. CC.3.5.11-12.E, Analyze how the text structures information or ideas into categories or hierarchies, demonstrating understanding of the information or ideas. CC.3.5.11-12.F, Analyze the author’s purpose in providing an explanation, describing a procedure, or discussing an experiment in a text, identifying important issues that remain unresolved. CC.3.5.11-12.G, Integrate and evaluate multiple sources of information presented in diverse formats and media (e.g., quantitative data, video, multimedia) in order to address a question or solve a problem. CC.3.5.11-12.H, Evaluate the hypotheses, data, analysis, and conclusions in a science or technical text, verifying the data when possible and corroborating or challenging conclusions with other sources of information. CC.3.5.11-12.I, Synthesize information from a range of sources (e.g., texts, experiments, simulations) into a coherent understanding of a process, phenomenon, or concept, resolving conflicting information when possible. CC.3.5.11-12.J, By the end of grade 12, read and comprehend science/technical texts in the grades 11–12 text complexity band independently and proficiently. Writing in Science and Technical Subjects: CC.3.6.11-12.A, Write arguments focused on discipline-specific content. CC.3.6.11-12.B, Write Page 16 of 57 Saucon Valley School District Planned Course of Study theories. Know that both direct and indirect observations are used by scientists to study the natural world and universe. Identify questions and concepts that guide scientific investigations. Formulate and revise explanations and models using logic and evidence. Recognize and analyze alternative explanations and models. Explain the importance of accuracy and precision in making valid measurements. Examine the status of existing theories. Evaluate experimental information for relevance and adherence to science processes. Judge that conclusions are consistent and logical with experimental conditions. Interpret results of experimental research to predict new information, propose additional investigable questions, or advance a solution. AP Biology Summer 2014 informative/explanatory texts, including the narration of historical events, scientific procedures/experiments, or technical processes. CC.3.6.11-12.C, Produce clear and coherent writing in which the development, organization, and style are appropriate to task, purpose, and audience. CC.3.6.11-12.D, Develop and strengthen writing as needed by planning, revising, editing, rewriting, or trying a new approach, focusing on addressing what is most significant for a specific purpose and audience. CC.3.6.11-12.E, Use technology, including the Internet, to produce, publish, and update individual or shared writing products in response to ongoing feedback, including new arguments or information. CC.3.6.11-12.F, Conduct short as well as more sustained research projects to answer a question (including a self-generated question) or solve a problem; narrow or broaden the inquiry when appropriate; synthesize multiple sources on the subject, demonstrating understanding of the subject under investigation. CC.3.6.11-12.G, Gather relevant information from multiple authoritative print and digital sources, using advanced searches effectively; assess the strengths and limitations of each source in terms of the specific task, purpose, and audience; integrate information into the text selectively to maintain the flow of ideas, avoiding plagiarism and overreliance on any one source and following a standard format for citation. CC.3.6.11-12.H, Draw evidence from informational texts to support analysis, reflection and research. Page 17 of 57 Saucon Valley School District Planned Course of Study CC.3.6.11-12.I, Write routinely over extended time frames (time for reflection and revision) and shorter time frames (a single sitting or a day or two) for a range of discipline-specific tasks, purposes, and audiences. Learning Objectives – The student will… LO 2.1: The student is able to explain how biological systems use free energy based on empirical data that all organisms require constant energy input to maintain organization, to grow and to reproduce. LO 2.2: The student is able to justify a scientific claim that free energy is required for living systems to maintain organization, to grow or to reproduce, but that multiple strategies exist in different living systems LO 2.3: The student is able to predict how changes in free energy availability affect organisms, populations and ecosystems. LO 2.4: the student is able to use representations to pose scientific questions about what mechanisms and structural features allow organisms to capture, store or use free energy. LO 2.6: The student is able to use calculated surface area-to-volume ratios to predict which cell(s) might eliminate wastes or procure nutrients faster by diffusion. LO 2.7: Students will be able to explain how cell size and shape affect the overall rate of nutrient intake and rate of waste elimination. LO 2.8: The student is able to justify the selection of data regarding the types of molecules that an animal, plant or bacterium will take up as necessary building blocks and excrete as waste products LO 2.9: The student is able to represent graphically or model quantitatively the exchange of molecules between an organism and its environment, and the subsequent use of these molecules to build new molecules that facilitate dynamic homeostasis, growth and reproduction. LO 2.10: The student is able to use representations and models to pose scientific questions about the properties of cell membranes and selective permeability based on molecular structure. LO 2.11: The student is able to construct models that connect the movement of molecules across membranes with membrane structure and function. LO 2.12: The student is able to use representations and models to analyze situations or solve problems qualitatively and quantitatively to investigate whether dynamic homeostasis is maintained by the active movement of molecules across membranes. LO 2.13: The student is able to explain how internal membranes and organelles contribute to cell functions. LO 2.14: The student is able to use representations and models to describe differences in prokaryotic and eukaryotic cells. AP Biology Summer 2014 Page 18 of 57 Saucon Valley School District Planned Course of Study LO 2.15: The student can justify a claim made about the effect(s) on a biological system at the molecular, physiological or organismal level when given a scenario in which one or more components within a negative regulatory system is altered. LO 2.16: The student is able to connect how organisms use negative feedback to maintain their internal environments. LO 2.17: The student is able to evaluate data that show the effects(s) of changes in concentrations of key molecules on negative feedback mechanisms. LO 2.18: The student can make predictions about how organisms use negative feedback mechanisms to maintain their internal environments. LO 2.19: The student is able to make predictions about how positive feedback mechanisms amplify activities and processes in organisms based on scientific theories and models. LO 2.20: The student is able to justify that positive feedback mechanisms amplify responses in organisms. LO 2.21: The student is able to justify the selection of the kind of data needed to answer scientific questions about the relevant mechanism the organisms use to respond to changes in their external environment. LO 2.22: The student is able to refine scientific models and questions about the effect of complex biotic and abiotic interactions on all biological systems, from cells and organisms to populations, communities and ecosystems. LO 2.23: The student is able to design a plan for collecting data to show that all biological systems (cells, organisms, populations, communities and ecosystems) are affected by complex biotic and abiotic interactions. LO 2.24: The student is able to analyze data to identify possible patterns and relationships between a biotic or abiotic factor and a biological system (cells, organisms, populations, communities or ecosystems). LO 2.25: The student can construct explanations based on scientific evidence that homeostatic mechanisms reflect continuity due to common ancestry and/or divergence due to adaptation in different environments. LO 2.26: The student is able to analyze data to identify phylogenic patterns or relationships, showing that homeostatic mechanisms reflect both continuity due to common ancestry and change due to evolution is different environments. LO 2.27: The student is able to connect differences in the environment with evolution of homeostatic mechanisms. LO 2.28: The student is able to use representations or models to analyze quantitatively the effects of disruptions to dynamic homeostasis in biological systems. LO 2.29: The student can create representations and models to describe immune responses. LO 2.30: The student can create representations or models to describe nonspecific defenses in plants and animals. LO 2.31: The student can connect concepts in and across domains to show that timing and coordination of specific events are necessary for normal development in an organism and that these events are regulated by multiple mechanisms. AP Biology Summer 2014 Page 19 of 57 Saucon Valley School District Planned Course of Study LO 2.32: The student is able to use a graph or diagram to analyze situations or solve problems (quantitatively or qualitatively) that involve timing and coordination of events necessary for normal development in an organism. LO 2.33: The student is able to justify scientific claims with scientific evidence to show that timing and coordination of several events are necessary for normal development in an organism and that these events are regulated by multiple mechanisms. LO 2.34: The student is able to describe the role of programmed cell death in development and differentiation, the reuse of molecules, and the maintenance of dynamic homeostasis. LO 2.35: The student is able to design a plan for collecting data to support the scientific claim that the timing and coordination of physiological events involve regulation. LO 2.36: The student is able to justify scientific claims with evidence to show how timing and coordination of physiological events involve regulation. LO 2.37: The student is able to connect concepts that describe mechanisms that regulate the timing and coordination of physiological events. LO 2.38: The student is able to analyze data to support the claim that responses to information and communication of information affect natural selection. LO 2.39: The student is able to justify scientific claims, using evidence, to describe how timing and coordination of behavioral events in organisms are regulated by several mechanisms. LO 2.40: The student is able to connect concepts in and across domain(s) to predict how environmental factors affect responses to information and change behavior. Essential Knowledge Concept and Content Connections 2.A.1: All living systems require constant input of free energy 2.A.1.a: Life requires a highly ordered system. 2.A.1.b: Living systems do not violate the second law of thermodynamics, which states that entropy increases over time. 2.A.1.c: Energy related pathways in biological systems are sequential and may be entered at multiple points in the pathway (see also 2.A.2) 2.A.1.d: Organisms use free energy to maintain organization, grow and reproduce 2.A.1.e: Changes in free energy availability can result in changes in population size 2.A.1.f: Changes in free energy availability can result in disruptions to an ecosystem. AP Biology Summer 2014 Page 20 of 57 Saucon Valley School District Planned Course of Study 2.A.2: Organisms capture and store free energy for use in biological processes 2.A.2.a: Autotrophs capture free energy from physical sources in the environment. 2.A.2.b: Heterotrophs capture free energy present in carbon compounds produced by other organisms. 2.A.2.c: Different energy-capturing processes use different types of electron acceptors. 2.A.2.e: Photosynthesis first evolved in prokaryotic organisms; scientific evidence supports that prokaryotic (bacterial) photosynthesis was responsible for the production of an oxygenated atmosphere; prokaryotic photosynthetic pathways were the foundation of eukaryotic photosynthesis. 2.A.2.f: Cellular respiration in eukaryotes involves a series of coordinated enzyme-catalyzed reactions that harvest free energy from simple carbohydrates. 2.A.2.g: The electron transport chain captures free energy from electrons in a series of coupled reactions that establish an electrochemical gradient across membranes. 2.A.2.h: Free energy becomes available for metabolism by the conversion of ATP ADP, which is coupled to many steps in metabolic pathways. 2.A.3: Organisms must exchange matter with the environment to grow, reproduce and maintain organization AP Biology Summer 2014 2.A.3.a: Molecules and atoms from the environment are necessary to build new molecules. 2.A.3.b: Surface area-to-volume ratios affect a biological system’s ability to obtain necessary resources or eliminate waste products. Page 21 of 57 Saucon Valley School District Planned Course of Study 2.B.1: Cell membranes are selectively permeable due to their structure 2.B.1.a: Cell membranes separate the internal environment of the cell from the external environment. 2.B.1.b: Selective permeability is a direct consequence of membrane structure, as described by the fluid mosaic model. (See also 4.A.1) 2.B.1.c: Cell walls provide a structural boundary, as well as a permeability barrier for some substances to the internal environments. 2.B: Growth, reproduction and dynamic homeostasis require that cells create and maintain internal environments that are different from their external environments 2.B.2: Growth and dynamic homeostasis are maintained by the constant movement of molecules across membranes 2.B.2.a: Passive transport does not require the input of metabolic energy; the net movement of molecules is from high concentration to low concentration. 2.B.2.b: Active transport requires free energy to move molecules from regions of low concentration to regions of high concentration. 2.B.2.c: The process of endocytosis and exocytosis move large molecules from the external environment to the internal environment and vice versa, respectively. 2.B.3: Eukaryotic cells maintain internal membranes that partition the cell into specialized regions 2.B.3.a: Internal membranes facilitate cellular processes by minimizing competing interactions and by increasing surface area where reactions can occur. 2.B.3.b: Membranes and membrane-bound organelles in eukaryotic cells localize (compartmentalize) intracellular metabolic processes and specific enzymatic reactions. (See also 4.A.2) 2.B.3.c: Archaea and Bacteria generally lack internal membranes and organelles and have a cell wall. AP Biology Summer 2014 Page 22 of 57 Saucon Valley School District Planned Course of Study 2.C.1: Organisms use feedback mechanisms to maintain their internal environments and respond to external environmental changes 2.C.1.a: Negative feedback mechanisms maintain dynamic homeostasis for a particular condition (variable) by regulating physiological processes, returning the changing condition back to its target set point. 2.C.1.b: positive feedback mechanisms amplify responses and processes in biological organisms. The variable initiating the response is moved farther away from the initial set point. Amplification occurs when the stimulus is further activated which, in turn, initiates an additional response that produces system change. 2.C.1.c: Alteration in the mechanisms of feedback often results in deleterious consequences. 2.C.2: Organisms respond to changes in their external environments 2.C.2.a: Organisms respond to changes in their environment through behavioral and physiological mechanisms. 2.D.1: All biological systems from cells and organisms to populations, communities and ecosystems are affected by complex biotic and abiotic interactions involving exchange of matter and free energy 2.D.1.a: Cell activities are affected by interactions with biotic and abiotic factors. 2.D.2: Homeostatic mechanisms reflect both common ancestry and divergence due to adaptation in different environments 2.D.2.a: Continuity of homeostatic mechanisms reflects common ancestry, while changes may occur in response to different environmental conditions (See also 1.B.1) 2.D.1.b: Organism activities are affected by interactions with biotic and abiotic factors. (See also 4.A.6) 2.D.1.c: The stability of populations, communities and ecosystems is affected by interactions with biotic and abiotic factors. (See also 4.A.5, 4.A.6) 2.D.2.b: Organisms have various mechanisms for obtaining nutrients and eliminating wastes. 2.D.2.c: Homeostatic control systems in species of microbes, plants and animals support common ancestry. (See also 1.B.1) 2.D.3: Biological systems are affected by disruptions to their dynamic homeostasis AP Biology Summer 2014 2.D.3.a: Disruptions at the molecular and cellular levels affect the health of the organism. 2.D.3.b: Disruptions to ecosystems impact the dynamic homeostasis or balance of the ecosystem. Page 23 of 57 Saucon Valley School District Planned Course of Study 2.D.4: Plants and animals have a variety of chemical defenses against infections that affect dynamic homeostasis 2.D.4.a: Plants, invertebrates and vertebrates have multiple, nonspecific immune responses. 2.E.1: Timing and coordination of specific events are necessary for the normal development of an organism, and these events are regulated by a variety of mechanisms 2.E.1.a: Observable cell differentiation results from the expression of genes for tissue-specific proteins. 2.E.2: Timing and coordination of physiological events are regulated by multiple mechanisms 2.E.2.a: In plants, physiological events involve interactions between environmental stimuli and internal molecular signals. (See also 2.C.3) 2.D.4.b: Mammals use specific immune responses triggered by natural or artificial agents that disrupt dynamic homeostasis. 2.E.1.b: Induction of transcription factors during development results in sequential gene expression. 2.E.1.c: Programmed cell death (apoptosis) plays a role in the normal development and differentiation. 2.E.2.b: In animals, internal and external signals regulate a variety of physiological response that synchronizes with environmental cycles and cues. 2.E.2.c: In fungi, protists and bacteria, internal and external signals regulate a variety of physiological responses that synchronize with environmental cycles and cues. 2.E.3: Timing and coordination of behavior are regulated by various mechanisms and are important in natural selection 2.E.3.a: Individuals can act on information and communicate it to others. 2.E.3.b: Responses to information and communication of information are vital to natural selection. (See also 2.C.3) Resources for this Unit Campbell Biology, 10th Edition (AP Edition) AP Biology Investigative Labs: An Inquiry-Based Approach (Published by College Board) Instructor's Resource CD/DVD-ROM Set For Campbell Biology, 10/E Mastering Biology With Mastering Biology Virtual Lab Full Suite-Instant Access-For Campbell Biology, 10/E Answer Key (Download Only) For Inquiry In Action: Interpreting Scientific Papers, 3/E AP Biology Summer 2014 Page 24 of 57 Saucon Valley School District Planned Course of Study Unit Title Unit Description Essential Questions & Enduring Understandings Unit 2 – Living Systems Living systems store, retrieve, transmit and respond to information essential to life processes.(Big Idea 3) 3.A: Heritable information provides for continuity of life. 3.B: Expression of genetic information involves cellular and molecular mechanisms. 3.C: The processing of genetic information is imperfect and is a source of genetic variation. 3.D: Cells communicate by generating, transmitting and receiving chemical signals. 3.E: Transmission of information results in changes within and between biological systems. PA Science Standards 3.1.B.A1, 3.1.B.A2, 3.1.B.A3, 3.1.B.A4, 3.1.B.A5, 3.1.B.A6, 3.1.B.A7, 3.1.B.A8, 3.1.B.A9 PA Core Literacy Standards for Science Reading in Science and Technical Subjects: CC.3.5.11-12.A, CC.3.5.11-12.B, CC.3.5.1112.C, CC.3.5.11-12.D, CC.3.5.11-12.E, CC.3.5.11-12.F, CC.3.5.11-12.G, CC.3.5.1112.H, CC.3.5.11-12.I, CC.3.5.11-12.J Writing in Science and Technical Subjects: CC.3.6.11-12.A, CC.3.6.11-12.B, CC.3.6.1112.C, CC.3.6.11-12.D, CC.3.6.11-12.E, CC.3.6.11-12.F, CC.3.6.11-12.G, CC.3.6.1112.H, CC.3.6.11-12.I Learning Objectives – The student will… LO 3.1: The student is able to construct explanations that use the structures and mechanisms of DNA and RNA to support the claim that DNA and, in some cases, that RNA are the primary sources of heritable information LO 3.2: The student is able to justify the selection of data from historical investigations that support the claim that DNA is the source of heritable information. AP Biology Summer 2014 Page 25 of 57 Saucon Valley School District Planned Course of Study LO 3.3: The student is able to describe representations and models that illustrate how genetic information is copied for transmission between generations. LO 3.4: The student is able to describe representations and models illustrating how genetic information is translated into polypeptides. LO 3.5: The student can justify the claim that humans can manipulate heritable information by identifying at least two commonly used technologies. LO 3.6: The student can predict how a change in a specific DNA or RNA sequence can result in changes in gene expression. LO 3.7: The student can make predictions about natural phenomena occurring during the cell cycle. LO 3.8: The student can describe the events that occur in the cell cycle. LO 3.9: The student is able to construct an explanation, using visual representations or narratives, as to how DNA in chromosomes is transmitted to the next generation via mitosis, or meiosis followed by fertilization. LO 3.10: The student is able to represent the connection between meiosis and increased genetic diversity necessary for evolution. LO 3.11: The student is able to evaluate evidence provided by data sets to support the claim that heritable information is passed from one generation to another generation through mitosis, or meiosis followed by fertilization. LO 3.12: The student is able to construct a representation that connects the process of meiosis to the passage of traits from parent to offspring. LO 3.13: The student is able to pose questions about ethical, social or medical issues surrounding human genetic disorders. LO 3.14: The student is able to apply mathematical routines to determine Mendelian patterns of inheritance provided by data sets. LO 3.15: The student is able to explain deviations from Mendel’s model of inheritance of traits. LO 3.16: The student is able to explain how the inheritance patterns of many traits cannot be accounted for by Mendelian genetics. LO 3.17: The student is able to describe representations of an appropriate example of inheritance patterns that cannot be explained by Mendel’s model of the inheritance of traits. LO 3.18: The student is able to describe the connection between the regulation of gene expression and observed differences between individuals in a population. LO 3.19: The student is able to describe the connection between the regulation of gene expression and observed differences between individuals in a population. LO 3.20: The student is able to explain how the regulation of gene expression is essential for the processes and structures that support efficient cell function. LO 3.21: The student can use representations to describe how gene regulation influences cell products and function. LO 3.22: The student is able to explain how signal pathways mediate gene expression, including how this process can affect protein production. LO 3.23: The student can use representations to describe mechanisms of the regulation of gene expression. AP Biology Summer 2014 Page 26 of 57 Saucon Valley School District Planned Course of Study LO 3.24: The student is able to predict how a change in genotype, when expressed as a phenotype, provides a variation that can be subject to natural selection. LO 3.25: The student can create a visual representation to illustrate how changes in a DNA nucleotide sequence can result in a change in the polypeptide produced. LO 3.26: The student is able to explain the connection between genetic variations in organisms and phenotypic variations in populations. LO 3.27: The student is able to compare and contrast processes by which genetic variation is produced and maintained in organisms from multiple domains. LO 3.28: The student is able to construct an explanation of the multiple processes that increase variation within a population. LO 3.29: The student is able to construct an explanation of how viruses introduce genetic variation in host organisms LO 3.30: The student is able to use representations and appropriate models to describe how viral replication introduces genetic variation in the viral population. LO 3.31: The student is able to describe basic chemical processes for cell communication shared across evolutionary lines of descent. LO 3.32: The student is able to generate scientific questions involving cell communication as it relates to the process of evolution. LO 3.33: The student is able to use representation(s) and appropriate models to describe features of a cell signaling pathway. LO 3.34: The student is able to construct explanations of cell communication through cell-to-cell direct contact or through chemical signaling. LO 3.35: The student is able to create representation(s) that depict how cell-to-cell communication occurs by direct contact or from a distance through chemical signaling. LO 3.36: The student is able to describe a model that expresses the key elements of signal transduction pathways by which a signal is converted to a cellular response. LO 3.37: The student is able to justify claims based on scientific evidence that changes in signal transduction pathways can alter cellular response. LO 3.38: The student is able to describe a model that expresses key elements to show how change in signal transduction can alter cellular response. LO 3.39: The student is able to construct an explanation of how certain drugs affect signal reception and, consequently, signal transduction pathways. LO 3.40: The student is able to analyze data that indicate how organisms exchange information in response to internal changes and external cues, and which can change behavior. LO 3.41: The student is able to create representation that describes how organisms exchange information in response to internal changes and external cues, and which can result in changes in behavior. LO 3.42: The student is able to describe how organisms exchange information in response to internal changes or environmental cues. LO 3.43: The student is able to construct an explanation, based on scientific theories and models, about how nervous systems detect external and internal signals, transmit and integrate information, and produce responses. AP Biology Summer 2014 Page 27 of 57 Saucon Valley School District Planned Course of Study LO 3.44: The student is able to describe how nervous systems detect external and internal signals. LO 3.45: The student is able to describe how nervous systems transmit information. LO 3.46: The student is able to describe how the vertebrate brain integrates information to produce a response. LO 3.47: The student is able to create a visual representation of complex nervous systems and to describe/explain how these systems detect external and internal signals, transmit and integrate information, and produce responses. LO 3.48: The student is able to create a visual representation to describe how nervous systems detect external and internal signals. LO 3.49: The student is able to create a visual representation to describe how nervous systems transmit information. LO 3.50: The student is able to create a visual representation to describe how the vertebrate brain integrates information to produce a response. Essential Knowledge Concept and Content Connections 3.A.1: DNA, and in some cases RNA, is the primary source of heritable information 3.A.1.a: Genetic information is transmitted from one generation to the next through DNA or RNA 3.A.1.b: DNA and RNA molecules have structural similarities and differences that define function. (See also 4.A.1) 3.A.1.c: Genetic information flows from a sequence of nucleotides in a gene to a sequence of amino acids in a protein. 3.A.1.d: Phenotypes are determined through protein activities. 3.A.1.e: Genetic engineering techniques can manipulate the heritable information of DNA and, in special cases, RNA. 3.A.2: In eukaryotes, heritable information is passed to the next generation via processes that include the cell cycle and mitosis or meiosis plus fertilization 3.A.2.a: The cell cycle is a complex set of stages that is highly regulated with checkpoints, which determine the ultimate fate of the cell. 3.A.2.b: Mitosis passes a complete genome from the parent cell to daughter cells. 3.A.2.c: Meiosis, a reduction division, followed by fertilization ensures genetic diversity in sexually reproducing organisms. AP Biology Summer 2014 Page 28 of 57 Saucon Valley School District Planned Course of Study 3.A.3: The chromosomal basis of inheritance provides an understanding of the pattern of passage (transmission) of genes from parents to offspring 3.A.3.a: Rules of probability can be applied to analyze passage of single gene traits from parent to offspring. 3.A.3.b: Segregation and independent assortment of chromosomes result in genetic variation. 3.A.3.c: Certain human genetic disorders can be attributed to the inheritance of single gene traits or specific chromosomal changes, such as nondisjunction. 3.A.3.d: Many ethical, social and medical issues surround human genetic disorders. 3.A.4: The inheritance pattern of many traits cannot be explained by simple Mendelian genetics 3.A.4.a: Many traits are the product of multiple genes and/or physiological processes. 3.A.4.b: Some traits are determined by genes on sex chromosomes. 3.A.4.c: Some traits result from nonnuclear inheritance. 3.B.1: Gene regulation results in differential gene expression, leading to cell specialization 3.B.1.a: Both DNA regulatory sequences, regulatory genes, and small regulatory RNA’s are involved in gene expression 3.B.1.b: Both positive and negative control mechanisms regulate gene expression in bacteria and viruses. 3.B.1.c: In eukaryotes, gene expression is complex and control involves regulatory genes, regulatory elements and transcription factors that act in concert. 3.B.1.d: Gene regulation accounts for some of the phenotypic differences between organisms with similar genes. 3.B.2: A variety of intercellular and intracellular signal transmissions mediate gene expression AP Biology Summer 2014 3.B.2.a: Signal transmission within and between cells mediates gene expression. 3.B.2.b: Signal transmission within and between cells mediates cell function. Page 29 of 57 Saucon Valley School District Planned Course of Study 3.C.1: Changes in genotype can result in changes in phenotype 3.C.1.a: Alterations in a DNA sequence can lead to changes in the type or amount of the protein produced and the consequent phenotype. (See also 3.A.1) 3.C.1.b: Errors in DNA replication or DNA repair mechanisms, and external factors, including radiation and reactive chemicals, can cause random changes, e.g., mutations in the DNA. 3.C.1.c: Errors in mitosis or meiosis can result in changes in phenotype. 3.C.1.d: Changes in genotype may affect phenotypes that are subject to natural selection. Genetic changes that enhance survival and reproduction can be selected by environmental conditions. (See also 1.A.2, 1.C.3) 3.C.2: Biological systems have multiple processes that increase genetic variation 3.C.2.a: The imperfect nature of DNA replication and repair increases variation. 3.C.2.b: The horizontal acquisitions of genetic information primarily in prokaryotes via transformation (uptake of naked DNA), transduction (viral transmission of genetic information), conjugation (cell-to-cell transfer) and transposition (movement of DNA segments within and between DNA molecules) increase variation. (See also 1.B.3) 3.C.2.c: Sexual reproduction in eukaryotes involving gamete formation, including crossing-over during meiosis and the random assortment of chromosomes during meiosis, and fertilization serve to increase variation. Reproduction processes that increase genetic variation are evolutionarily conserved and are shared by various organisms. (See also 1.B.1, 3.A.2, 4.C.2, 4.C.3) 3.C.3: Viral replication results in genetic variation, and viral infection can introduce genetic variation into the hosts 3.C.3.a: Viral replication differs from other reproductive strategies and generates genetic variation via various mechanisms. (See also 1.B.3) 3.D.1: Cell communication processes share common features that reflect a shared evolutionary history 3.D.1.a: Communication involves transduction of stimulatory or inhibitory signals from other cells, organisms or the environment. (See also 1.B.1) AP Biology Summer 2014 3.C.3.b: The reproductive cycles of viruses facilitate transfer of genetic information. 3.D.1.b: Correct and appropriate signal transduction processes are generally under strong selective pressure. Page 30 of 57 Saucon Valley School District Planned Course of Study 3.D.1.c: In single-celled organisms, signal transduction pathways influence how the cell responds to its environment. 3.D.1.d: In multicellular organisms, signal transduction pathways coordinate the activities within individual cells that support the function of the organism as a whole. 3.D.1: Cell communication processes share common features that reflect a shared evolutionary history 3.D.1.a: Communication involves transduction of stimulatory or inhibitory signals from other cells, organisms or the environment. (See also 1.B.1) 3.D.1.b: Correct and appropriate signal transduction processes are generally under strong selective pressure. 3.D.1.c: In single-celled organisms, signal transduction pathways influence how the cell responds to its environment. 3.D.1.d: In multicellular organisms, signal transduction pathways coordinate the activities within individual cells that support the function of the organism as a whole. 3.D.2: Cells communicate with each other through direct contact with other cells or from a distance via chemical signaling 3.D.2.a: Cells communicate by cell-to-cell contact. 3.D.3: Signal transduction pathways link signal reception with cellular response 3.D.3.a: Signaling begins with the recognition of a chemical messenger, a ligand, by a receptor protein. 3.D.4: Changes in signal transduction pathways can alter cellular response 3.D.4.a: Conditions where signal transduction is blocked or defective can be deleterious, preventative or prophylactic. 3.E.1: Individuals can act on information and communicate it to others 3.E.1.a: Organisms exchange information with each other in response to internal changes and external cues, which can change behavior. 3.D.2.b: Cells communicate over short distances by using local regulators that target cells in the vicinity of the emitting cell. 3.D.2.c: Signals released by one cell type can travel long distances to target cells of another cell type. 3.D.3.b: Signal transduction is the process by which a signal is converted to a cellular response. 3.E.1.b: Communication occurs through various mechanisms. 3.E.1.c: Responses to information and communication of information are vital to natural selection and evolution. (See also 1.A.2) AP Biology Summer 2014 Page 31 of 57 Saucon Valley School District Planned Course of Study 3.E.2: Animals have nervous systems that detect external and internal signals, transmit and integrate information, and produce responses 3.E.2.a: The neuron is the basic structure of the nervous system that reflects function. 3.E.2.b: Action potentials propagate impulses along neurons. 3.E.2.c: Transmission of information between neurons occurs across synapses. 3.E.2.d: Different regions of the vertebrate brain have different functions. Resources for this Unit Campbell Biology, 10th Edition (AP Edition) AP Biology Investigative Labs: An Inquiry-Based Approach (Published by College Board) Instructor's Resource CD/DVD-ROM Set For Campbell Biology, 10/E Mastering Biology With Mastering Biology Virtual Lab Full Suite-Instant Access-For Campbell Biology, 10/E Answer Key (Download Only) For Inquiry In Action: Interpreting Scientific Papers, 3/E AP Biology Summer 2014 Page 32 of 57 Saucon Valley School District Planned Course of Study Unit Title Unit Description Essential Questions & Enduring Understandings Unit 3 – Process of Evolution The process of evolution drives the diversity and unity of life (Big Idea 1) 1.A: Change in the genetic makeup of a population over time is evolution. 1.B: Organisms are linked by lines of descent from common ancestry. 1.C: Life continues to evolve within a changing environment. 1.D: The origin of living systems is explained by natural processes. PA Science Standards 3.1.B.A1, 3.1.B.A2, 3.1.B.A3, 3.1.B.A4, 3.1.B.A5, 3.1.B.A6, 3.1.B.A7, 3.1.B.A8, 3.1.B.A9 PA Core Literacy Standards for Science Reading in Science and Technical Subjects: CC.3.5.11-12.A, CC.3.5.11-12.B, CC.3.5.1112.C, CC.3.5.11-12.D, CC.3.5.11-12.E, CC.3.5.11-12.F, CC.3.5.11-12.G, CC.3.5.1112.H, CC.3.5.11-12.I, CC.3.5.11-12.J Writing in Science and Technical Subjects: CC.3.6.11-12.A, CC.3.6.11-12.B, CC.3.6.1112.C, CC.3.6.11-12.D, CC.3.6.11-12.E, CC.3.6.11-12.F, CC.3.6.11-12.G, CC.3.6.1112.H, CC.3.6.11-12.I Learning Objectives – The student will… LO 1.1: The student is able to convert a data set from a table of numbers that reflect a change in the genetic makeup of a population over time and to apply mathematical methods and conceptual understandings to investigate the cause(s) and effect(s) of this change. LO 1.2: The student is able to evaluate evidence provided by data to qualitatively and quantitatively investigate the role of natural selection in evolution. LO 1.3: The student is able to apply mathematical methods to data from a real or simulated population to predict what will happen to the population in the future. LO 1.4: The student is able to evaluate data-based evidence that describes evolutionary changes in the makeup of a population over time. AP Biology Summer 2014 Page 33 of 57 Saucon Valley School District Planned Course of Study LO 1.5: The student is able to connect evolutionary changes in a population over time to a change in the environment. LO 1.6: The student is able to use data from mathematical models based on the Hardy-Weinberg equilibrium to analyze genetic drift and effects of selection in evolution of specific populations. LO 1.7: The student is able to justify data from mathematical models based on the HardyWeinberg equilibrium to analyze genetic drift and the effects of selection in the evolution of specific populations. LO 1.8: The student is able to make predictions about the effects of genetic drift, migration and artificial selection on the genetic makeup of a population. LO 1.9: The student is able to evaluate evidence provided by data from many scientific disciplines that support biological evolution. LO 1.10: The student is able to refine evidence based on data from many scientific disciplines that support biological evolution. LO 1.11: The student is able to design a plan to answer scientific questions regarding how organisms have changed over time using information from morphology, biochemistry and geology. LO 1.12: The student is able to connect scientific evidence from many scientific disciplines to support the modern concept of evolution. LO 1.13: The student is able to construct and/or justify mathematical models, diagrams or simulations that represent processes of biological evolution. LO 1.14: The student is able to pose scientific questions that correctly identify essential properties of shared, core life processes that provide insights into the history of life on Earth. LO 1.15: The student is able to describe specific examples of conserved core biological processes and features shared by all domains or within one domain of life, and how these shared, conserved core processes and features support the concept of common ancestry for all organisms. LO 1.16: The student is able to justify the scientific claim that organisms share many conserved core processes and features that evolved and are widely distributed among organisms today. LO 1.17: The student is able to pose scientific questions about a group of organisms whose relatedness is described by a phylogenic tree or cladogram in order to (1) identify shared characteristics, (2) make inferences about the evolutionary history of the group, and (3) identify character data that could extend or improve the phylogenic tree. LO 1.18: The student is able to evaluate evidence provided by a data set in conjunction with a phylogenic tree or a simple cladogram to determine evolutionary history and speciation. LO 1.19: The student is able create a phylogenic tree or simple cladogram that correctly represents evolutionary history and speciation from a provided data set. LO 1.20: The student is able to analyze data related to questions of speciation and extinction throughout the Earth’s history. LO 1.21: The student is able to design a plan for collecting data to investigate the scientific claim that speciation and extinction have occurred throughout the Earth’s history. LO 1.22: The student is able to use data from a real or simulated population(s), based on graphs or models of types of selection, to predict what will happen to the population in the future. AP Biology Summer 2014 Page 34 of 57 Saucon Valley School District Planned Course of Study LO 1.23: The student is able to justify the selection of data that address questions related to reproductive isolation and speciation. LO 1.24: The student is able to describe speciation in an isolated population and connect it to change in gene frequency, change in environment, natural selection and/or genetic drift. LO 1.25: The student is able to describe a model that represents evolution within a population. LO 1.26: The student is able to evaluate given data sets that illustrate evolution as an ongoing process. LO 1.27: The student is able to describe a scientific hypothesis about the origin of life on Earth. LO 1.28: The student is able to evaluate scientific questions based on hypotheses about the origin of life on Earth. LO 1.29: The student is able to describe the reasons for revisions of scientific hypotheses of the origin of life on Earth. LO 1.30: The student is able to evaluate scientific hypotheses about the origin of life on Earth. LO 1.31: The student is able to evaluate the accuracy and legitimacy of data to answer scientific questions about the origin of life on Earth. LO 1.32: The student is able to justify the selection of geological, physical, and chemical data that reveal early Earth conditions. Essential Knowledge Concept and Content Connections 1.A.1: Natural selection is a major mechanism of evolution 1.A.1.a: According to Darwin’s theory of natural selection, competition for limited resources results in differential survival. Individuals with more favorable phenotypes are more likely to survive and produce more offspring, thus passing traits to subsequent generations. 1.A.1.b: Evolutionary fitness is measured by reproductive success. 1.A.1.c: Genetic variation and mutation play roles in natural selection. A diverse gene pool is important for the survival of a species in a changing environment. 1.A.1.d: Environments can be more or less stable or fluctuating, and this affects evolutionary rate and direction; different genetic variations can be selected in each generation. 1.A.1.e: An adaptation is a genetic variation that is favored by selection and is manifested as a trait that provides and advantage to an organism in a particular environment 1.A.1.f: In addition to natural selection, chance and random events can influence the evolutionary process, especially for small populations. AP Biology Summer 2014 Page 35 of 57 Saucon Valley School District Planned Course of Study 1.A.1.g: Conditions for a population or an allele to be in HardyWeinberg equilibrium are: (1) a large population size, (2) absence of migration, (3) no net mutations, (4) random mating and (5) absence of selection. These conditions are seldom met. 1.A.1.h: Mathematical approaches are used to calculate changes in allele frequency, providing evidence for the occurrence of evolution in a population. 1.A.2: Natural selection acts on phenotypic variations in populations 1.A.2.a: Environments change and act as selective mechanism on populations. 1.A.2.b: Phenotypic variations are not directed by the environment but occur through random changes in the DNA and through new gene combinations 1.A.2.c: Some phenotypic variations significantly increase or decrease fitness of the organism and the population. 1.A.2.d: Humans impact variation in other species 1.A.3: Evolutionary change is 1.A.3.a: Genetic drift is a nonselective process occurring in small also driven by random populations processes 1.A.3.b: Reduction of genetic variation within a given population can increase the differences between populations of the same species. 1.A.4: Biological evolution is supported by scientific evidence from many disciplines, including mathematics 1.A.4.a: Scientific evidence of biological evolution uses information from geographical, geological, physical, chemical, and mathematical applications. 1.B.1: Organisms share many conserved core processes and features that evolved and are widely distributed among organisms today 1.B.1.a: Structural and functional evidence supports the relatedness of all domains. AP Biology Summer 2014 1.A.4.b: Molecular, morphological and genetic information of existing and extinct organisms add to our understanding of evolution. 1.B.1.b: Structural evidence supports the relatedness of all eukaryotes. (See also 2.B.3, 4.A.2) Page 36 of 57 Saucon Valley School District Planned Course of Study 1.B.2: Phylogenic trees and cladograms are graphical representations (models) of evolutionary history that can be tested 1.B.2.a: Phylogenic trees and cladograms can represent traits that are either derived or lost due to evolution 1.B.2.b: Phylogenic trees and cladograms illustrate speciation that has occurred, in that relatedness of any two groups on the tree is shown by how recently two groups had a common ancestor. 1.B.2.c: Phylogenic trees and cladograms can be constructed from morphological similarities of living or fossil species, and from DNA and protein sequence similarities, by employing computer programs that have sophisticated ways of measuring and representing relatedness among organisms. 1.B.2.d: Phylogenic trees and cladograms are dynamic (i.e., phylogenic trees and cladograms are constantly being revised), based on biological data used, new mathematical and computational ideas, and current and emerging knowledge. 1.C.1: Speciation and extinction have occurred throughout the Earth’s history 1.C.1.a: Speciation rates can vary; especially when adaptive radiation occurs when new habitats become available. 1.C.2: Speciation may occur when two populations become reproductively isolated from each other 1.C.2.a: Speciation results in diversity of life forms. Species can be physically separated by a geographic barrier such as an ocean or mountain range, or various pre- and post-zygotic mechanisms can maintain reproductive isolation and prevent gene flow. 1.C.1.b: Species extinction rates are rapid at times of ecological stress. (See also 4.C.3) 1.C.2.b: New species arise from reproductive isolation over time, which can involve scales of hundreds of thousands or even millions of years, or speciation can occur rapidly through mechanisms such as polyploidy in plants. 1.C.3: Populations of organisms continue to evolve 1.C.3.a: Scientific evidence supports the idea that evolution has occurred in all species. 1.D.1: There are several hypotheses about the natural origin of life on Earth, each with supporting scientific evidence 1.D.1.a: Scientific evidence supports the various models. AP Biology Summer 2014 1.C.3.b: Scientific evidence supports the idea that evolution continues to occur. Page 37 of 57 Saucon Valley School District Planned Course of Study 1.D.2: Scientific evidence from many different disciplines supports models of the origin of life 1.D.2.a: Geological evidence provides support for models of the origin of life on Earth. Resources for this Unit Campbell Biology, 10th Edition (AP Edition) AP Biology Investigative Labs: An Inquiry-Based Approach (Published by College Board) Instructor's Resource CD/DVD-ROM Set For Campbell Biology, 10/E Mastering Biology With Mastering Biology Virtual Lab Full Suite-Instant Access-For Campbell Biology, 10/E Answer Key (Download Only) For Inquiry In Action: Interpreting Scientific Papers, 3/E AP Biology Summer 2014 Page 38 of 57 Saucon Valley School District Planned Course of Study Unit Title Unit Description Essential Questions & Enduring Understandings Unit 4 – Biological Interactions Biological systems interact, and these systems and their interactions posses complex properties. (Big Idea 4) 4.A: Interactions within biological systems lead to complex properties. 4.B: Competition and cooperation are important aspects of biological systems. 4.C: Naturally occurring diversity among and between components within biological systems affects interactions with the environment. PA Science Standards 3.1.B.A1, 3.1.B.A2, 3.1.B.A3, 3.1.B.A4, 3.1.B.A5, 3.1.B.A6, 3.1.B.A7, 3.1.B.A8, 3.1.B.A9 PA Core Literacy Standards for Science Reading in Science and Technical Subjects: CC.3.5.11-12.A, CC.3.5.11-12.B, CC.3.5.1112.C, CC.3.5.11-12.D, CC.3.5.11-12.E, CC.3.5.11-12.F, CC.3.5.11-12.G, CC.3.5.1112.H, CC.3.5.11-12.I, CC.3.5.11-12.J Writing in Science and Technical Subjects: CC.3.6.11-12.A, CC.3.6.11-12.B, CC.3.6.1112.C, CC.3.6.11-12.D, CC.3.6.11-12.E, CC.3.6.11-12.F, CC.3.6.11-12.G, CC.3.6.1112.H, CC.3.6.11-12.I Learning Objectives – The student will… LO 4.1: The student is able to explain the connection between the sequence and subcomponents of a biological polymer and its properties. LO 4.2: The student is able to refine representations and models to explain how the subcomponents of a biological polymer and their sequence determine the properties of that polymer. LO 4.3: The student is able to use models to predict and justify that changes in the subcomponents of a biological polymer affect the functionality of the molecule. LO 4.4: The student is able to make a prediction about the interactions of subcellular organelles. LO 4.5: The student is able to construct explanations based on scientific evidence as to how interactions of subcellular structures provide essential functions. AP Biology Summer 2014 Page 39 of 57 Saucon Valley School District Planned Course of Study LO 4.6: The student is able to use representations and models to analyze situations qualitatively to describe how interactions of subcellular structures, which possess specialized functions, provide essential functions. LO 4.7: The student is able to refine representations to illustrate how interactions between external stimuli and gene expression result in specialization of cells, tissues and organs. LO 4.8: The student is able to evaluate scientific questions concerning organisms that exhibit complex properties due to the interaction of their constituent parts. LO 4.9: The student is able to predict the effects of a change in a component(s) of a biological system on the functionality of an organism(s). LO 4.10: The student is able to refine representations and models to illustrate biocomplexity due to interactions of the constituent parts. LO 4.11: The student is able to justify the selection of the kind of data needed to answer scientific questions about the interaction of populations within communities. LO 4.12: The student is able to apply mathematical routines to quantities that describe communities composed of populations of organisms that interact in complex ways. LO 4.13: The student is able to predict the effects of a change in the community’s populations on the community. LO 4.14: The student is able to apply mathematical routines to quantities that describe interactions among living systems and their environment, which result in the movement of matter and energy. LO 4.15: The student is able to use visual representations to analyze situations or solve problems qualitatively to illustrate how interactions among living systems and with their environment result in the movement of matter and energy. LO 4.16: The student is able to predict the effects of a change of matter or energy availability on communities. LO 4.17: The student is able to analyze data to identify how molecular interactions affect structure and function. LO 4.18: The student is able to use representations and models to analyze how cooperative interactions within organisms promote efficiency in the use of energy and matter. LO 4.19: The student is able to use data analysis to refine observations and measurements regarding the effect of population interactions on patterns of species distribution and abundance. LO 4.20: The student is able to explain how the distribution of ecosystems changes over time by identifying large-scale events that have resulted in these changes in the past. LO 4.21: The student is able to predict consequences of human actions on both local and global ecosystems. LO 4.22: The student is able to construct explanations based on evidence of how variation in molecular units provides cells with a wider range of functions. LO 4.23: The student is able to construct explanations of the influence of environmental factors on the phenotype of an organism. LO 4.24: The student is able to predict the effects of a change in an environmental factor on the genotypic expression of the phenotype. AP Biology Summer 2014 Page 40 of 57 Saucon Valley School District Planned Course of Study LO 4.25: The student is able to use evidence to justify a claim that a variety of phenotypic responses to a single environmental factor can result from different genotypes within the population. LO 4.26: The student is able to use theories and models to make scientific claims and/or predictions about the effects of variation within populations on survival and fitness. LO 4.27: The student is able to make scientific claims and predictions about how species diversity within an ecosystem influences ecosystem stability. Essential Knowledge Concept and Content Connections 4.A.1: The subcomponents of biological molecules and their sequence determine the properties of that molecule 4.A.1.a: Structure and function of polymers are derived from the way their monomers are assembled. 4.A.2: The structure and function of subcellular components, and their interactions, provide essential cellular processes 4.A.2.a: Ribosomes are small, universal structures comprised of two interacting parts: ribosomal RNA and protein. In a sequential manner, these components interact to become the site of protein synthesis where the translation of the genetic instructions yields specific polypeptides. (See also 2.B.3) 4.A.1.b: Directionality influences structure and function of the polymer. 4.A.2.b: Endoplasmic reticulum (ER) occurs in two forms: smooth and rough. (See also 2.B.3) 4.A.2.c: The Golgi complex is a membrane-bound structure that consists of a series of flattened membrane sacs (cisternae). (See also 2.B.3) 4.A.2.d: Mitochondria specialize in energy capture and transformation. (See also 2.A.2, 2.B.3) 4.A.2.e: Lysosomes are membrane-enclosed sacs that contain hydrolytic enzymes, which are important in intracellular digestion, the recycling of a cell’s organic materials and programmed cell death (apoptosis). Lysosomes carry out intracellular digestion in a variety of ways. (See also 2.A.3, 2.B.3) 4.A.2.f: A vacuole is a membrane-bound sac that plays a role in intracellular digestion and the release of cellular waste products. In plants, a large vacuole serves many functions, from storage of pigments or poisonous substances to a role in cell growth. In addition, a large central vacuole allows for a large surface area to volume ratio. (See also 2.A.3, 2.B.3) AP Biology Summer 2014 Page 41 of 57 Saucon Valley School District Planned Course of Study 4.A.2.g: Chloroplasts are specialized organelles found in algae and higher plants that capture energy through photosynthesis. (See also 2.A.2, 2.B.3) 4.A.3: Interactions between external stimuli and regulated gene expression result in specialization of cells, tissues and organs 4.A.3.a: Differentiation in development is due to external and internal cues that trigger gene regulation by proteins that bind to DNA. (See also 3.B.1, 3.B.2) 4.A.3.b: Structural and functional divergence of cells in development is due to expression of genes specific to a particular tissue or organ type. (See also 3.B.1, 3.B.2) 4.A.3.c: Environmental stimuli can affect gene expression in a mature cell. (See also 3.B.1, 3.B.2) 4.A.4: Organisms exhibit complex properties due to interactions between their constituent parts 4.A.4.a: Interactions and coordination between organs provide essential biological activities. 4.A.5: Communities are composed of populations of organisms that interact in complex ways 4.A.5.a: The structure of a community is measured and described in terms of species composition and species diversity. 4.A.4.b: Interactions and coordination between systems provide essential biological activities. 4.A.5.b: Mathematical and computer models are used to illustrate and investigate population interactions within and environmental impacts on a community. (See also 3.E.1, 3.E.3) 4.A.5.c: Mathematical models and graphical representations are used to illustrate population growth patterns and interactions. 4.A.6: Interactions among living systems and with their environment result in the movement of matter and energy 4.A.6.a: Energy flows, but matter is recycled. (See also 2.A.1) 4.A.6.b: Changes in regional and global climates and in atmospheric composition influence patterns of primary productivity. 4.A.6.c: Organisms within food webs and food chains interact. (See also 2.D.1) 4.A.6.d: Food webs and food chains are dependent on primary productivity. 4.A.6.e: Models allow the prediction of the impact of change in biotic and abiotic factors. AP Biology Summer 2014 Page 42 of 57 Saucon Valley School District Planned Course of Study 4.A.6.f: Human activities impact ecosystems on local, regional, and global scales. (See also 2.D.3) 4.A.6.g: Many adaptations of organisms are related to obtaining and using energy and matter in a particular environment. (See also 2.A.1, 2.A.2) 4.B.1: Interactions between molecules affect their structure and function 4.B.1.a: Change in the structure of a molecular system may result in a change of the function of the system. (See also 3.D.3) 4.B.1.b: The shape of enzymes, active sites and interaction with specific molecules are essential for basic functioning of the enzyme. 4.B.1.c: Other molecules and the environment in which the enzyme acts can enhance or inhibit enzyme activity. Molecules can bind reversibly or irreversibly to the active or allosteric sites, changing the activity of the enzyme. 4.B.1.d: The change in function of an enzyme can be interpreted from data regarding the concentrations of product or substrate as a function of time. These representations demonstrate the relationship between an enzyme’s activity, the disappearance of substrate, and/or presence of a competitive inhibitor. 4.B.3: Interactions between and within populations influence patterns of species distribution and abundance 4.B.3.a: Interactions between populations affect the distributions and abundance of populations. 4.B.3.b: A population of organisms has properties that are different from those of the individuals that make up the population. The cooperation and competition between individuals contributes to these different properties. 4.B.3.c: Species-specific and environmental catastrophes, geological events, the sudden influx/depletion of abiotic resources or increased human activities affect species distribution and abundance. (See also 1.A.1, 1.A.2) 4.B.4: Distribution of local and global ecosystems changes over time 4.B.4.a: Human impact accelerates change at local and global levels. (See also 1.A.2) 4.C.1: Variation in molecular units provides cells with a wider range of functions 4.C.1.a: Variations within molecular classes provide cells and organisms with a wider range of functions. (See also 2.B.1, 3.A.1, 4.A.1, 4.A.2) AP Biology Summer 2014 4.B.4.b: Geological and meteorological events impact ecosystem distribution. Page 43 of 57 Saucon Valley School District Planned Course of Study 4.C.1.b: Multiple copies of alleles or genes (gene duplication) may provide new phenotypes. (See also 3.A.4, 3.C.1) 4.C.2: Environmental factors influence the expression of the genotype in an organism 4.C.2.a: Environmental factors influence many traits both directly and indirectly. (See also 3.B.2, 3.C.1) 4.C.3: The level of variation in a population affects population dynamics 4.C.3.a: Population ability to respond to changes in the environment is affected by genetic diversity. Species and populations with little genetic diversity are at risk for extinction. (See also 1.A.1, 1.A.2, 1.C.1) 4.C.2.b: An organism’s adaptation to the local environment reflects a flexible response of its genome. 4.C.3.b: Genetic diversity allows individuals in a population to respond differently to the same changes in environmental conditions. 4.C.3.c: Allelic variation within a population can be modeled by the Hardy-Weinberg equation(s). (See also 1.A.1) 4.C.4: The diversity of species within an ecosystem may influence the stability of the ecosystem 4.C.4.a: Natural and artificial ecosystems with fewer component parts and with little diversity among the parts are often less resilient to changes in the environment. (See also 1.C.1) 4.C.4.b: Keystone species, producers, and essential abiotic and biotic factors contribute to maintaining the diversity of an ecosystem. The effects of keystone species on the ecosystem are disproportionate relative to their abundance in the ecosystem, and when they are removed from the ecosystem, the ecosystem often collapses. Resources for this Unit Campbell Biology, 10th Edition (AP Edition) AP Biology Investigative Labs: An Inquiry-Based Approach (Published by College Board) Instructor's Resource CD/DVD-ROM Set For Campbell Biology, 10/E Mastering Biology With Mastering Biology Virtual Lab Full Suite-Instant Access-For Campbell Biology, 10/E Answer Key (Download Only) For Inquiry In Action: Interpreting Scientific Papers, 3/E AP Biology Summer 2014 Page 44 of 57 Saucon Valley School District Planned Course of Study Appendix A Key Vocabulary by Chapter in Campbell Biology 10th Edition Chapter Name List of Key Vocabulary Evolution, the Themes of Evolution, biology, biosphere, ecosystem, community, Biology, and Scientific Inquiry population, organism, organ, organ system, tissue, molecule, cell, organelle, reductionism, emergent property, systems biology, eukaryote, prokaryote, gene, DNA, RNA, gene expression, genome, genomics, proteome, bioimformatics, producer, consumer, feedback regulation, negative feedback, positive feedback, bacteria, archaea, eukarya, natural selection, science, data, inductive reasoning, deductive reasoning, experiment, hypothesis, theory, variable, controlled experiment, independent variable, dependent variable, model organism, technology Carbon and the Molecular Organic chemistry, hydrocarbon, isomer, structural Diversity of Life isomer, cis-trans isomer, enantiomers, functional group, ATP The Structure and Function of Macromolecule, polymer, monomer, enzyme, dehydration Large Biological Molecules reaction, hydrolysis, carbohydrate, monosaccharide, disaccharide, glycosidic linkage, polysaccharide, starch, glycogen, cellulose, chitin, lipid, fat, fatty acid, triacylglycerol, saturated fatty acid, unsaturated fatty acid, phospholipid, steroid, cholesterol, catalyst, polypeptide, protein, amino acid, R group, peptide bond, sickle-cell disease, denaturation, chaperonins, X-ray crystallography, gene, nucleic acid, DNA, RNA, gene expression, polynucleotide, nucleotide, nucleoside, pyrimidine, purine, deoxyribose, ribose, double helix, antiparallel, genomics, proteonomics AP Biology Summer 2014 Page 45 of 57 Saucon Valley School District Planned Course of Study A Tour of the Cell Membrane Structure and Function An Introduction to Metabolism AP Biology Summer 2014 Organelle, electron microscope, scanning electron microscope, transmission electron microscope, cell fractionation, cytosol, nucleoid, cytoplasm, plasma membrane, nucleus, nuclear envelope, nuclear lamina, chromosome, chromatin, nucleolus, ribosome, endomembrane system, vesicle, endoplasmic reticulum (ER), smooth ER, rough ER, glycoprotein, transport vesicle, golgi apparatus, lysosome, phagocytosis, vacuole, food vacuole, contractile vacuole, central vacuole, mitochondrion, chloroplast, endosymbiont theory, cristae, mitochondrial matrix, thylakoid, granum, stroma, plastid, peroxisome, cytoskeleton, motor protein, microtubule, microfilament, intermediate filament, centrosome, centriole, flagella, cilia, basal body, dynein, actin, myosin, pseudopod, cytoplasmic streaming, intermediate filament, cell wall, primary cell wall, middle lamella, secondary cell wall, extracellular matrix (ECM), collagen, proteoglycan, fibronectin, integrin, plasmodesmata, tight junction, desmosome, gap junction Selective permeability, amphipathic, fluid mosaic model, integral protein, peripheral protein, glycolipid, glycoprotein, transport protein, aquaporin, diffusion, concentration gradient, passive transport, osmosis, tonicity, isotonic, hypertonic, hypotonic, osmoregulation, turgid, flaccid, plasmolysis, facilitated diffusion, ion channel, gated channel, active transport, sodiumpotassium pump, membrane potential, electrochemical gradient, electrogenic pump, proton pump, cotransport, exocytosis, ligand, pinocytosis, receptor-mediated endocytosis Fermentation, aerobic respiration, cellular respiration, redox reactions, oxidation, reduction, reducing agent, oxidizing agent, NAD+/NADH, electron transport chain, glycolysis, citric acid cycle (Krebs cycle), oxidative phosphorylation, substrate-level phosphorylation, acetyl CoA, chemiosmosis, proton-motive force, alcoholic fermentation, lactic acid fermentation, obligate aerobe, obligate anaerobe, facultative anaerobe, beta oxidation Page 46 of 57 Saucon Valley School District Planned Course of Study Photosynthesis Cell Communication The Cell Cycle Meiosis and Sexual Life Cycles AP Biology Summer 2014 Photosynthesis, autotroph, photoautotroph, heterotroph, mesophyll, stomata, stroma, thylakoid, chlorophyll, light reactions, Calvin cycle (light-independent reactions), NADP+/NADPH, photophosphorylation, carbon fixation, wavelength, electromagnetic spectrum, visible light, photon, spectrophotometer, absorption spectrum, chlorophyll a, chlorophyll b, action spectrum, carotenoids, photosystem, reaction-center, light-harvesting complex, primary electron acceptor, photosystem II, photosystem I, linear electron flow, cyclic electron flow, glyceraldehyde 3phosphate (G3P), rubisco, C3 plants, photorespiration, C4 plants, bundle-sheath cells, PEP carboxylase, CAM plants, Hormone, reception, transduction, response, signal transduction pathway, ligand, G protein-coupled receptor, receptor tyrosine kinase, ligand-gated ion chanel, intracellular receptor, cascade, phosphorylation cascade, protein kinase, protein phosphatase, second messenger, cyclic AMP (cAMP), adenylyl cyclase, inositol triphosphate (IP3), diacylglycerol (DAG), signal amplification, scaffolding proteins, apoptosis Cell division, cell cycle, genome, chromosome, chromatin, somatic cell, gamete, sister chromatid, centromere, cytokinesis, mitotic (M) phase, interphase, G1 phase, S phase, G2 phase, prophase, prometaphase, metaphase, anaphase, telophase, mitotic spindle, centrosome, aster, kinetochore, metaphase plate, cleavage, cleavage furrow, cell plate, binary fission, origin of replication, cell cycle control system, checkpoint, cyclin, cyclin-dependent kinase (Cdks), maturation promoting factor (MPF), G0 phase, growth factor, density-dependent inhibition, anchorage dependence, transformation Heredity, variation, genetics, gene, gamete, somatic cell, locus, asexual reproduction, clone, sexual reproduction, karyotype, homologous chromosomes, sex chromosomes, autosomes, diploid cell, haploid cell, fertilization, zygote, meiosis, alteration of generations, meiosis I, meiosis II, synaptonemal complex, synapsis, crossing over, recombinant chromosome Page 47 of 57 Saucon Valley School District Planned Course of Study Mendel and the Gene Idea The Chromosomal Basis of Inheritance The Molecular Basis of Inheritance AP Biology Summer 2014 Character, true-breeding, hybridization, P generation, F1 generation, F2 generation, allele, dominant allele, recessive allele, law of segregation, punnett square, homozygous, heterozygous, phenotype, genotype, testcross, monohybrids, monohybrid cross, dihybrid, dihybrid cross, law of independent assortment, multiplication rule, addition rule, complete dominance, incomplete dominance, codominance, Tay-Sachs disease, pleiotropy, epistasis, quantitative character, polygenic inheritance, pedigree, cystic fibrosis, sickle-cell disease, multifactoral disorder, amniocentesis, chorionic villus sampling (CVS), Chromosome theory of inheritance, wild type, sex-linked gene, X-linked gene, Duchenne muscular dystrophy, hemophilia, Barr body, linked genes, genetic recombination, parental type, recombinant type, crossing over, genetic map, linkage map, map units, nondisjunction, aneuploidy, momosomatic, trisomatic, polyploidy, triploidy, tetraploidy, deletion, duplication, inversion, translocation, Down syndrome, genomic imprinting DNA replication, transformation, virus, Chargraff’s rule, double helix, antiparallel, semiconservative model, origin of replication, replication fork, helicase, single-stranded binding protein, topoisomerase, primer, primase, DNA polymerases, antiparallel elongation, leading strand, lagging strand, Okazaki fragments, DNA ligase, mismatch repair, nuclease, nucleotide excision repair, telomere, telomerase, chromatin, histone, nucleosome, heterochromatin, euchromatin Page 48 of 57 Saucon Valley School District Planned Course of Study Gene Expression: From Gene to Protein Gene expression, transcription, messenger RNA (mRNA), translation, ribosome, primary transcript, triplet code, template strand, codon, reading frame, RNA polymerase, promoter, terminator, transcription unit, start point, transcription factors, transcription initiation complex, TATA box, RNA processing, 5’ cap, poly-A tail, RNA splicing, introns, exons, spliceosome, ribozymes, alternative RNA splicing, protein domain, transfer RNA (tRNA), anticodon, aminoacyl-tRNA synthetases, tRNA wobble, ribosomal RNAs (rRNAs), P site, A site, E site, elongation, signal peptide, signal-recognition particle (SRP), polyribosomes (polysomes), mutation, point mutation, nucleotide-pair substitution, silent mutation, missense mutation, nonsense mutation, insertion, deletion, frameshift mutation, mutagen Regulation of Gene Expression Operator, operon, repressor, regulatory gene, corepressor, repressible operon, inducer, inducible operon, activator, differential gene expression, histone acetylation, DNA methylation, epigenetic inheritance, control elements, enhancers, proximal control elements, distal control elements, mediator proteins, combinatorial control of gene activation, alternative RNA splicing, microRNAs (miRNAs), small interfering RNAs (siRNAs), RNA interference (RNAi), chromatin remodeling, noncoding RNAs (ncRNAs), differentiation, morphogenesis, cytoplasmic determinants, induction, pattern formation, positional information, homeotic genes, embryonic lethals, maternal effect gene, egg-polarity genes, morphogens, oncogenes, proto-oncogenes, tumor-supressor genes, p53 gene Viruses Virus, capsid, viral envelope, bacteriophage (phage), host range, lytic cycle, virulent phage, restriction enzymes, lysogenic cycle, temperate phage, prophage, retrovirus, reverse transcriptase, HIV (human immunodeficiency virus), AIDS (acquired immunodeficiency syndrome), provirus, vaccine, epidemic, pandemic, prion Genomes and Their Evolution Genomics, bioimformatics, whole-genome shotgun approach, metagenomics, gene annotation, systems biology, pseudogenes, repetitive DNA, transposable elements, transposons, retrotransposons, simple sequence DNA, short tandem repeat (STR), multigene families, homeobox AP Biology Summer 2014 Page 49 of 57 Saucon Valley School District Planned Course of Study Descent with Modification: A Darwinian View of Life Evolution, fossil, strata, paleontology, adaptation, natural selection, artificial selection, homology, homologous structures, vestigial structures, evolutionary tree, convergent evolution, analogous structures, Pangea, biogeography, endemic The Evolution of Populations Microevolution, genetic variation, neutral variation, gene pool, Hardy-Weinberg equilibrium, adaptive evolution, genetic drift, founder effect, bottleneck effect, gene flow, relative fitness, directional selection, disruptive selection, stabilizing selection, sexual selection, sexual dimorphism, intrasexual selection, intersexual selection, balancing selection, heterozygote advantage, frequency-dependent selection, The Origin of Species Speciation, microevolution, macroevolution, biological species concept, species, reproductive isolation, hybrid, prezygotic barrier, postzygotic barrier, habitat isolation, temporal isolation, behavioral isolation, mechanical isolation, gametic isolation, reduced hybrid viability, reduced hybrid fertility, hybrid breakdown, morphological species concept, ecological species concept, phylogenic species concept, allopatric speciation, sympatric speciation, polyploidy, autopolyploid, allopolyploid, hybrid zone, punctuated equilibrium The History of Life on Earth Macroevolution, protocell, hydrothermal vent, alkaline vent, ribozyme, radiometric dating, half-life, synapsid, therapsid, cynodont, geologic record, stromatolite, endosymbiont theory, serial endosymbiosis, Cambrian explosion, plate tectonics, mass extinction, adaptive radiation, heterochrony, paedomorphosis, homeotic genes Phylogeny and the Tree of Life Phylogeny, taxonomy, binomial nomenclature, genus, family, order, class, phyla, domain, taxon, phylogenic tree, branch point, sister taxa, rooted, basal taxon, polytomy, homoplasies, cladistics, clade, monophyletic, paraphyletic, polyphyletic, shared ancestral character, shared derived character, outgroup, ingroup, maximum parsimony, maximum likelihood, orthologous genes, paralogous genes, molecular clock, horizontal gene transfer AP Biology Summer 2014 Page 50 of 57 Saucon Valley School District Planned Course of Study The Origin and Evolution of Vertebrates Plant Structure, Growth, and Development Resource Acquisition and Transport in Vascular Plants AP Biology Summer 2014 Vertebrate, chordate, notochord, pharyngeal cleft, lancelets, tunicates, hagfishes, lampreys, cyclosomes, conodonts, gnathostomes, lateral line system, placoderms, acanthodians, chondrichthyans, oviparous, ovoviviparous, viviparous, cloaca, osteichthyans, operculum, ray-finned fishes, lobe-fins, tetrapod, amphibian, amniote, amniotic egg, reptile, parareptile, diapsid, lepidosaurs, archosaurs, pterosaurs, dinosaurs, theropods, turtles, crocodilians, mammals, synapsids, monotremes, marsupials, placenta, eutherians, primates, opposable thumbs, anthropoids, paleoanthropology, hominins, Autralopiths, bipedialism, Homo, Neanderthals Organ, tissue, root system, shoot system, root, lateral root, taproot, root hair, stem, node, internode, apical bud, axillary bud, leaf, blade, petiole, vein, tissue system, dermal tissue system, epidermis, cuticle, periderm, vascular tissue system, xylem, phloem, stele, ground tissue system, pith, cortex, indeterminate growth, meristem, determinate growth, apical meristem, primary growth, secondary growth, lateral meristem, vascular cambium, cork cambium, annual, biennial, perennial, root cap, endodermis, pericycle, leaf primordial, apical dominance, stomata, guard cell, mesophyll, lenticels, bark, polarity, pattern formation, phase changes, meristem identity genes, organ identity genes, ABC hypothesis Xylem, phloem, phyllotaxy, mycorrhizae, apoplast, symplast, water potential, solute potential, pressure potential, protoplast, turgor pressure, flaccid, plasmolysis, turgid, wilting, aquaporins, bulk flow, endodermis, Casparian strip, xylem sap, transpiration, root pressure, guttation, cohesion-tension hypothesis, circadian rhythms, abscistic acid (ABA), xerophytes, translocation, phloem sap, sugar source, sugar sink, Page 51 of 57 Saucon Valley School District Planned Course of Study Angiosperm Reproduction and Biotechnology Plant Responses to Internal and External Signals Basic Principles of Animal Form and Function AP Biology Summer 2014 Carpels, stamens, petals, sepals, receptacle, ovary, style, stigma, ovules, pistil, anther, complete flowers, incomplete flowers, inflorescences, megaspores, microspores, pollen grain, pollination, pollen tube, fertilization, endosperm, double fertilization, coevolution, dormancy, seed coat, hypocotyl, radicle, epicotyl, coleptile, coleorhiza, imbibition, fruit, simple fruit, aggregate fruit, multiple fruit, accessory fruits, fragmentation, apomixis, vegetative reproduction, dioecious, self-incompatibility, totipotent, vegetative propagation, callus, stock, scion, transgenic, Etiolation, de-etiolation, tropism, phototropism, auxin, expansins, cytokinins, gibberellin, ethylene, triple response, senescence, Brassinosteroids, Jasmonates, Strigolactones, photomorphogenesis, action potential, blue-light photoreceptors, phytochromes, photoperiodism, short-day plant, long-day plant, day-neutral plant, vernalization, florigen, gravitropism, statoliths, thigmomorphogenesis, thigmotropism, action potential, heat-shock proteins, pathogen-associated molecular patterns (PAMPs), effectors, hypersensitive response, systemic acquired resistance, salicylic acid, herbivory Anatomy, physiology, interstitial fluid, tissues, organs, organ system, endocrine system, nervous system, hormones, regulator, conformer, homeostasis, set point, stimulus, sensor, response, negative feedback, positive feedback, acclimatization, thermoregulation, endotherm, ectotherm, integumentary system, countercurrent exchange, hypothalamus, bioenergetics, metabolic rate, basal metabolic rate (BMR), standard metabolic rate (SMR), torpor, hibernation, Page 52 of 57 Saucon Valley School District Planned Course of Study Circulation and Gas Exchange The Immune System AP Biology Summer 2014 Gastrovascular cavity, heart, open circulatory system, hemolymph, closed circulatory system, blood, cardiovascular system, arteries, arterioles, capillaries, capillary beds, venules, veins, atria, ventricles, single circulation, double circulation, systemic circuit, cardiac cycle, systole, diastole, cardiac output, heart rate, stroke volume, atrioventricular (AV) valve, semilunar valve, heart murmur, sinoatrial (SA) node, atrioventricular (AV) node, endothelium, systolic pressure, pulse, diastolic pressure, vasoconstriction, vasodilation, lymphatic system, lymph, lymph nodes, plasma, platelets, erythrocytes, hemoglobin, leukocytes, platelets, stem cells, erythropoietin, thrombus, atherosclerosis, low-density lipoprotein (LDL), highdensity lipoprotein (HDL), heart attack, stroke, hypertension, gas exchange, partial pressure, ventilation, countercurrent exchange, tracheal system, larynx, trachea, bronchi, bronchioles, alveoli, surfactant, positive pressure breathing, negative pressure breathing, diaphragm, tidal volume, vital capacity, residual volume, respiratory pigments, Bohr shift, myoglobin, Pathogen, immune system, innate immunity, adaptive immunity, lysozyme, hemocytes, phagocytosis, Toll-like receptors (TLR), neutrophil, macrophage, dendritic cell, natural killer cell, interferon, complement system, inflammatory response, histamine, mast cell, lymphocyte, thymus, T cell, B cell, antigen, antigen receptor, epitope, antibody, heavy chain, light chain, immunoglobulin, major histocompatibility complex molecule (MHC), antigen presentation, immunological memory, effector cells, plasma cell, memory cell, clonal selection, humoral immune response, cell-mediated immune response, helper T cell, antigen presenting cell, cytotoxic T cell, opsonization, membrane attack complex, IgA, IgE, IgG, IgM, IgD, active immunity, passive immunity, immunization, monoclonal antibody, allergy, allergen, autoimmune disease, immunodeficiency, Page 53 of 57 Saucon Valley School District Planned Course of Study Osmoregulation and Excretion Osmoregulation, excretion, osmolarity, osmoconformer, osmoregulator, stenohaline, euryhaline, anhydrobiosis, transport epithelia, ammonia, uric acid, urea, filtration, filtrate, reabsorption, secretion, protonephridia, metanephridia, Malpighian tubules, kidney, ureter, urinary bladder, urethra, renal cortex, renal medulla, renal pelvis, nephron, cortical nephron, juxtamedullary nephron, glomerulus, Bowman’s capsule, proximal tubule, loop of Henle, distal tubule, collecting duct, peritubular capillaries, vasa recta, aquaporin, current multiplier system, antidiuretic hormone (ADH), vasopressin, renninangiotensin-aldosterone system (RAAS), juxtaglomerular apparatus (JGA), angiotensin II, aldosterone, atrial natriuretic peptide (ANP) Hormones and the Endocrine Hormone, endocrine system, nervous system, local System regulator, paracrine, autocrine, prostaglandins, neurotransmitter, neurohormone, pheromone, nitric oxide (NO), signal transduction, epinephrine, endocrine gland, oxytocin, negative feedback, positive feedback, hypothalamus, pituitary gland, posterior pituitary, anterior pituitary, antidiuretic hormone (ADH), prolactin, tropic hormones, thyroid hormone, thyroid gland, parathyroid glands, parathyroid hormone (PTH), calcitonin, adrenal glands, norepinephrine, epinephrine, catecholamines, glucocorticoids, mineralocorticoids, androgens, testosterone, estrogens, estradiol, progestins, progesterone, endocrine disrupters, melatonin, pineal gland, Melanocyte-stimulating hormone (MSH) AP Biology Summer 2014 Page 54 of 57 Saucon Valley School District Planned Course of Study Neurons, Synapses, and Signaling Nervous Systems Sensory and Motor Mechanisms AP Biology Summer 2014 Neuron, brain, ganglia, cell body, dendrite, axon, synapse, neurotransmitter, glial cells (glia), sensory neuron, interneuron, motor neuron, central nervous system (CNS), peripheral nervous system (PNS), nerve, membrane potential, resting potential, sodium-potassium pump, ion channels, equilibrium potential (Eion), gated ion channel, hyperpolarization, depolarization, graded potential, action potential, voltage-gated ion channel, threshold, refractory period, myelin sheath, oligodendrocytes, Schwann cells, nodes of Ranvier, saltatory conduction, ligand-gated ion channel, excitatory postsynaptic potential (EPSP), inhibitory postsynaptic potential (IPSP), temporal summation, spatial summation, acetylcholine, glutamate, gamma-aminobutyric acid (GABA), biogenic amines, dopamine, serotonin, neuropeptide, endorphins, Central nervous system, peripheral nervous system, ganglia, glial cells, astrocytes, central canal, gray matter, white matter, reflexes, motor system, autonomic nervous system, enteric division, sympathetic division, parasympathetic division, forebrain, midbrain, hindbrain, biological clock, suprachiasmic nucleus (SCN), limbic system, amygdala, lateralization, neuronal plasticity, short-term memory, long-term memory, long-term potential (LTP), schizophrenia, major depressive disorder, bipolar disorder, Alzheimer’s disease, Parkinson’s disease Sensory reception, sensory receptor, sensory transduction, receptor potential, perception, amplification, sensory adaptation, mechanoreceptors, chemoreceptors, electromagnetic receptors, thermoreceptors, nociceptors (pain receptors), statocysts, statoliths, hair cells, round window, utricle, saccule, lateral line system, photoreceptors, compound eye, ommatidia, single-lens eye, pupil, iris, fovea, gustation, olfaction, tastants, odorants, taste buds, thin filaments, thick filaments, skeletal muscle, myofibrils, sarcomere, sliding-filament model, tropomyosin, troponin complex, transverse (T) tubules, sarcoplasmic reticulum (SR), motor unit, tetanus, myoglobin, fast-twitch fibers, slow-twitch fibers, cardiac muscle, intercalated discs, smooth muscle, hydrostatic skeleton, peristalsis, exoskeleton, chitin, endoskeleton, locomotion Page 55 of 57 Saucon Valley School District Planned Course of Study Animal Behavior An Introduction to Ecology Population Ecology Community Ecology AP Biology Summer 2014 Behavior, behavioral ecology, fixed action pattern, sign stimulus, migration, signal, communication, pheromones, innate behavior, cross-fostering study, twin study, learning, imprinting, sensitive period, spatial learning, cognitive map, associative learning, cognition, problem solving, social learning, culture, foraging, optimal foraging model, monogamous, polygamous, mate-choice copying, game theory, altruism, coefficient of relatedness, Hamilton’s rule, kin selection, reciprocal altruism, sociobiology Ecology, climate, macroclimate, microclimate, abiotic, biotic, climograph, ecotone, canopy, disturbance, photic zone, aphotic zone, pelagic zone, abyssal zone, benthic zone, benthos, detritus, thermocline, turnover, dispersal, Population density, dispersion, immigration, emigration, territoriality, demography, survivorship curve, reproductive table, zero population growth, exponential population growth, carrying capacity, logistic population growth, semelparity, iteroparity, K-selection, r-selection, density independent, density dependent, population dynamics, metapopulation, demographic transition, age structure, ecological footprint Community, interspecific interactions, interspecific competition, competitive exclusion, ecological niche, resource partitioning, character displacement, aposematic coloration, cryptic coloration, Batesian mimicry, Mullerian mimicry, herbivory, symbiosis, parasitsm, host, endoparasite, ectoparasite, mutualism, commensaliam, facilitation, species diversity, species richness, relative abundance, Shannon diversity, biomass, invasive species, trophic structure, food web, energetic hypothesis, keystone species, ecosystem engineers, bottom-up model, top-down model, biomanipulation, disturbance, nonequilibrium model, intermediate disturbance hypothesis, ecological succession, primary succession, secondary succession, evapotranspiration, species-area curve, zoonotic pathogens, vector Page 56 of 57 Saucon Valley School District Planned Course of Study Ecosystems and Restoration Ecology AP Biology Summer 2014 Law of conservation of mass, primary producers, primary consumers, secondary consumers, tertiary consumers, detritivores, decomposers, detritus, primary production, gross primary production (GPP), net primary productivity (NPP), net ecosystem production (NEP), limiting nutrient, eutrophication, secondary production, production efficiency, trophic efficiency, turnover time, biogeochemical cycle, bioremediation, biological augmentation Page 57 of 57