Association Mapping of Complex Traits in Crop Plants

Association Mapping of Complex Traits in Crop Plants
Key Issues in Statistical Analysis and Candidate Gene/Allele Discovery and Validation
Guoping Shu, Tabare Abadie, Geoff Graham, Zeng Li, and Antoni Rafalski
Pioneer Hi-Bred International, DuPont Crop Genetics, EI DuPont de Nemours & Co., Johnston, IA, 50131,
Wilmington, DE, 19898, USA
With the availability of high density genomic and genetic map of SNP and SSR Markers for crop plants,
association mapping becomes increasingly powerful tool for genetic and molecular dissection of complex
and quantitative traits. We will discuss the key issues in Association mapping for crop plants: the statistical
methods of genome scan mapping and fine mapping, separating phenotype association from linkage
disequilibrium, sample size and detection power, discovery and validation of candidate genes and candidate