Unit 3 Biology
Applications of Immunology
Guiding Questions
1. When were vaccine first developed?
2. What is the role of a vaccine?
3. How has molecular biology contributed to the development of vaccines?
4.
5.
6.
7.
8.
What are MHC molecules?
What happens if a T cell recognises an MHC molecule as non-self?
What is tissue typing and why is it important for organ transplantation?
What does HLA stand for?
Approximately many different HLA types are possible?
9. What is immunotherapy?
10. Name two applications of immunotherapy.
11. How does desensitization work?
12. What happens when normal cells turn into cancer cells?
13. What is one theory on how tumour cells develop?
14. Name two different cancer treatments that seek to exploit the immune response.
15. What do dendritic cells normally do?
16. What do researchers aim to achieve by modifying dendritic cells?
17. How are these dendritic cells used to treat cancer?
18.
19.
20.
21.
How does immunotherapy work for cancer?
What sort of molecules may be attached to the antibody targeting the cancer cell?
What are the two types of antibodies that can be therapeutic antibodies?
Outline two key differences between monoclonal and polyclonal antibodies.
22. How are monoclonal antibodies made?
23. How is antivenom made?
24. What makes immuno-compromised mice a good model for exploring human bone marrow
transplantation?