GRADE-8 SCIENCE UNIT 3: The Evolution of Life on Earth *Course chapters #6-8 Chapter 6: Chapter 7: Chapter 8: Heredity and Genetics DNA and Reproduction Evolution Introduction Every organism alive today comes from a long line of ancestors who reproduced successfully in every generation. Reproduction is the transfer of genetic information from one generation to the next. Heredity is the passing of traits from parents to offspring. It can occur with mixing of genes from two individuals (sexual reproduction) or it can occur with the transfer of genes from one individual to the next generation (asexual reproduction). The ability to reproduce defines living things. The process of reproduction drives changes in life through both the mixing and mutations of genetic information from one generation to the next. Through the process of natural selection, new traits that are helpful to survival within a particular environment are passed on while new traits that are harmful to survival within a particular environment tend to die out. Over long periods of time, this process changes the “face of life” on our planet and the evolution of new species from old. Course “chapter 6” correlates to part of chapter 5 from Holt Life Science textbook. Ch.6 Study Guide Topic 1: The Mystery of Heredity Read pages 114-116 (Holt Life Science) 1. The passing of traits from parents to offspring is known as _______________________. A trait is a physical characteristic of an organism that is largely determined by genetic information, such as eye or hair color. The first scientists credited with major discoveries in the understanding of heredity was __________________________ _____________________________. 2. He decided to limit his investigations to a single organism. He used _________________ _______________________ because he was familiar with them and they grow quickly. They are also able to both ______________-pollinate and ________________-pollinate. 3. True-breeding results from _____________ - pollination. In this case, the offspring will always have the ________________ traits as the parent. 4. Cross-pollination results when pollen is carried by _____________________ or _____________________ from one flower to another. This results in a mixing of traits and produces offspring that are not identical to their parents. 5. A ___________________________ is a feature that has different forms in a population. The different forms themselves are known as __________________. Three characteristics of pea plants studied by Mendel were _______________________, ________________________, and __________________________. tier 2&3 CROs: CRO 1: Why are the patterns of inheritance not always clear? CRO 2: (Research) Other than hair and eye color, identify three other traits that are passed down through generations. CRO3: Why were pea plants a good organism to use when investigating heredity? CRO4: What does it mean to say that a plant is “self-pollinating”? Compare (and contrast) this with “cross-pollination”. Topic 2: Mendel’s Experiments Read pages 117-120 1. Mendel “crossed” plants with different characteristics, meaning he ___________pollinated them. The plants produced by this are called ________________________________________ plants. These offspring all had the same ________________ for each characteristic, even through the plants he crossed had different ones. 2. The trait that appears in all first-generation offspring is called the ____________________ _________________. In the case of the pea-plant color, it is the color ________________________. The trait that seems to disappear in the first generation of offspring is called the __________________________ _______________. 3. In Mendel’s second set of experiments, he allowed the first-generation of offspring to _______________ - pollinate. When he did this, he found that _______ out of every 4 plants displayed the ________________________ trait. 4. The results of Mendel’s experiments can only be explained if each plant have _______________ sets of instructions for each characteristic. Each parent would then donate _________ set(s). 5. These sets of instructions are now known as ____________________. As a result of cross-pollination in plants (or sexual reproduction in animals), offspring have two forms of the same gene for every characteristic (one from each parent). The different forms of a gene are known as ____________________. Tier 2&3 CROs: 1. What is the difference between a trait and a characteristic? Give one example of each. 2. Describe Mendel’s first set of experiments (procedure and outcome). 3. Describe Mendel’s second set of experiments (procedure and outcome). 4. Answer Critical Thinking question #9 on page 119. 5. Research: Identify three dominant traits (dominant alleles) and three recessive traits (recessive alleles) in humans. Topic 3: Genetics Read pages 120-125 1. An organism’s appearance (as based on its genes) is known as its _________________________________. This depends on how the alleles are expressed in an individual. Both alleles (for each trait) together form an organism’s __________________________________. This can be thought of as the entire genetic make-up of an organism. 2. The phenotype depends on the combination of alleles in the genotype AND the probability of each allele being expressed. If a genotype consists of two dominant alleles or two recessive alleles is said to be _________________________. The phenotype of the organism has only one possibility (that of the dominant or recessive allele respectively). This is what occurred in Mendel’s first experiment since ___________________ is the dominant color and dominant alleles are always expressed over recessive alleles in a genotype. It is only when both alleles in a genotype are recessive that they are expressed (become the phenotype). 3. If a genotype consists of a combination of dominant and recessive alleles it is said to be __________________________________. In this case, four combinations of alleles are possible (dominant-dominant, dominant-recessive, recessivedominant, and recessive-recessive) but only _________ phenotypes are possible. *This is what occurred in Mendel’s second experiment since each plant had both alleles from cross-pollination in the first experiment. This explains why roughly ________ in four plants were the color ________________ (since the allele for this color is recessive and both alleles in a genotype must be recessive to be expressed as the phenotype). 4. During reproduction, each parent passes on _________ of its ___________ alleles to its offspring. If the parent has two different alleles for a gene, each type has a(n) __________________ chance of being passed on. The genotype of the offspring results from a combination of alleles from the parents. 5. A _______________________ ______________________ is used to organize all the possible combinations of genotypes based on the combination of alleles passed on from the parents. This consists of ___________ boxes inside of a square. 6. (A) If both parents both pass on a dominant allele, the offspring has a ________ % probability of a dominant trait phenotype and a ________ % chance of a recessive trait phenotype. (B) If both parents pass on a recessive allele, the offspring has a ________ % probability of a dominant trait phenotype and a ________ % chance of a recessive trait phenotype. (C) If one parent passes on a dominant allele and the other a recessive allele, the offspring has a ________ % probability of a dominant trait phenotype and a ________ % chance of a recessive trait phenotype. Tier 2&3 CROs: 1. Red hair in humans is a recessive trait and is rare because both parents must pass on the allele for red hair to their offspring for them to have red hair. Describe why both parents, rather than just one, must pass on this allele (use a Punnet square to illustrate). Must both parents have red hair to have an offspring with red hair? Explain. 2. As it applies to CRO #1, describe the probability of having an offspring with red hair if: i. Neither parent has red hair but carries the allele for it. ii. One parent has red hair and the other does not but carries the allele for it. iii. Both parents have red hair as their phenotype. 3. On page 125 in textbook, answer #3. Draw a Punnet square to support your answer. 4. On page 125 in textbook, answer #7. Draw a Punnet square to support your answer. 5. On page 125 in textbook, answer #8&9. ALL TIERS- extension assignment Visit the website genetics.thetech.org and select “online exhibits”, then select “what color eyes will your children have?” Survey your parents and find out their eye color and the eye color of their parents (your grandparents) if known. Enter your dad’s eye color in the box “You” and your mom’s color in the box “Your mate”. Enter your grandparent’s eye color from your dad’s side in the boxes “Your Mother” and “Your Father” and your grandparents on your mom’s side in the boxes “Mate’s Mother” and Mate’s Father”. See if this produces a genotype that matches your eye color and the probability of your actual eye color (phenotype). Print out this page and submit. Your eye color may not come up as a possible genotype. This does not necessarily mean that mom and dad are not your biological parents but rather that other genes that influence eye color have had an affect. You may wish to have some fun and re-work this scenario for your children given the eye color of your future husband or wife (hypothetically, of course). Topic 4: Exceptions to the Rule Read pages 124-125 1. Since Mendel’s discoveries, researchers have found that sometimes one trait or allele is not completely dominant over another. When these alleles combine, each has its own degree of influence in the overall phenotype (expressed trait). This situation is known as _____________________ _______________________. As an example, in the snapdragon the red-color allele and the white-color-allele “co-dominant” and produce a flower color that is _________________. 2. In many cases one gene influences more than one ___________________. Also, some traits are the result of several ___________________ acting together. An example of the latter is in the case of many different ________________________ shades in people. These traits are referred to as being “polygenetic”. 3. In addition to the genotype of an organism, many physical traits (phenotypes) are also affected by the ______________________________. For instance, how tall a tree grows depends on climate and how tall a person grows depends in part on diet. *There is much research underway to study the affects on the environment on how genotypes are expressed. There is some evidence that genes themselves may be altered by diet, exercise, exposure to radiation and pollution, drug use, etc. ALL TIERS- extension assignment Visit the website genetics.thetech.org and select “online exhibits”, then select “DNA roulette”. Press “click to begin”. On a sheet of notebook paper, identify the 10 genetic characteristics listed on the “choose a game” page and for each, identify what amount (%) of the characteristic is genetic (the remaining % is based on environmental factors). For each characteristic, play the genetic roulette game. For each characteristic, list the general population odds for a person of Northern European descent (from round 2). Then, list the odds for the genotype of your person (from round 3). From the general population odds (round two of betting), determine the dominant and recessive alleles involved. Then, from the odds for the genotype of your test subject (round three), determine whether both, one, or neither of the person’s parents likely had that characteristic. An example is shown below bitter-taste perception: o 99 % genetic ; 1 % environmental factors o general population (northern european)= 75:25 for bitter taste perception o “Sheila” DNA = 99% chance for bitter taste perception Dominant = bitter-taste perception (can taste PTC) Recessive= can’t taste PTC o Sheila’s genotype possibilities= TT, Tt, tt (25%); based on odds she will likely express the TT or Tt genotype. o Parents = Both have Tt phenotype and thus both had bitter taste perception (most likely). You will need to copy numbers and bet quickly, as there is a time limit for each bet. You can analyze data after playing the round. Do not complete for traits involving three or more possible characteristics such as eye color. “A decade ago, reading off one single human genome was a billion-dollar effort. Today, the price tag is around $8,000 and falling fast; it will soon be feasible to sequence each person’s complete DNA as part of routine medicine” – Elaine Mardis, co-director of the Genome Institute at Washington University (St.Louis) in DISCOVER magazine January 2014.