The Delaware Valley Drug Metabolism Discussion Group Presents
On December 4, 2014
“DMPK in Special Populations”
DRAFT AGENDA
Morning session (8.30 am – noon)
1. "Creating a Reflective Virtual Population: Determinants of Variability in ADME in Health
and Disease" by Amin Rostami, University of Manchester
2. "Medication Challenges in the Geriatric Population" by Judith L. Beizer, St. John's University
3. "Hypnotic drugs and women: What is the risk?" by David Greenblatt, Tufts University School
of Medicine and Tufts Medical Center
4. “Drug Interaction Studies with Oral Contraceptives to Inform Contraception Options for
Women with Child-Bearing Potential: Merck’s Experience” by Ying-Hong Wang, Merck
Lunch Break (noon – 1.15 pm)
Afternoon session (1.15 – 3.45 pm)
5. “Modeling Renal Drug Transport and Toxicity in a 3D Human Kidney Microphysiological
System” by Ed Kelly, University of Washington
6. “Impact of Disease-associated Inflammation and Immunotherapy on Drug Metabolizing
Enzymes and Transporters” by Eddie Morgan, Emory University
7. ““Role of Drug Efflux Transporters in Antiretroviral Therapy in the Context of HIV-1 BrainAssociated Inflammation” by Reina Bendayan, University of Toronto