Name: _______________________________ Genetics 314 – Spring, 2006 Exam 4 – 100 points Part 1 – 82 points: Answer all questions 1. What are Mendel’s two laws and how do they relate to events in meiosis? 2. You are studying six traits in a plant and all six traits are on different chromosomes. You mate the following genotypes: Aa DD Ee Ff gg Ll x Aa Dd Ee Ff Gg Ll Out of 3000 progeny how many of the following genotypes would you expect to recover? 1) 2) 3) 4) AA DD EE FF Gg LL Aa Dd Ee Ff Gg Ll aa dd ee ff gg ll aa Dd Ee ff Gg Ll 1 Name: _______________________________ 3. Since you recently finished a degree at the University of Idaho that required a genetics class, you are asked by some recently married members of your extended family if you could help them determine the odds of having certain combinations of kids. If the couples want to have 7 children, calculate the probabilities for the following combinations: a) b) c) d) 6 boys – 1 girl 4 boys – 3 girls 2 boys – 5 girls 0 boys – 7 girls 4. If someone said they wanted their children in a specific order (boy – girl – boy – girl – boy – girl – boy) would the probability change from what you calculated for 3b? Briefly explain your answer. 5. You are studying coat color in rabbits and are told that there are 6 alleles for coat color. a) With six alleles how many genotypes would you have if five of the alleles were codominant and one was recessive? b) Would you expect the same number of phenotypes as genotypes? Briefly explain your answer. 2 Name: _______________________________ 6. You are asked to look at some concordance data on twins to determine which traits are under more genetic control and which are under more environmental control. You are given the following data: trait depression high blood pressure dependability leadership skills cholesterol level identical twins 78% 65% 85% 70% 68% fraternal twins 40% 30% 83% 67% 25% a) Which traits are under more genetic control? b) Which traits are under more environmental control? c) Why would some traits under more genetic control have a relatively low level of concordance in identical twins? 7. You are studying the expression of coat color in animals and observe a genotype in the F1 you have never observed before. Suspecting you are observing epistasis you mate the F1 and observe the following progeny: phenotype dark brown light brown white total number 103 77 14 194 a) What type of gene action are you observing? b) Test your hypothesis using Chi square analysis (please show your work). . 3 Name: _______________________________ 8. Working with fruit flies you study three genes that you think are on the same chromosome. The traits are long wing (L – long, l – normal), big abdomen ( B – big, b – normal) and flying speed (N – normal, n – slow). You cross true breeding parents to produce F1 progeny that are completely heterozygous for the traits. You mate the F1 flies with a homozygous recessive flies (ll bb nn) and recover the following F2 progeny: genotype number L b n l B N 2,250 2,275 L B n l b N 280 310 L b N l B n 155 165 l b n L B N 8 7 total 5450 a) What were the genotypes of the true breeding parents? b) What is the gene order? c) Draw a gene map of the three genes showing the genetic distance between the genes. d) What is the interference value for these genes? 4 Name: _______________________________ Part 2. - 18 points: Answer 3 of the following 4 questions 9. You are observing a trait in cattle and discover an odd inheritance pattern. The trait will appear in both male and female progeny if the father expresses the trait. If the mother is the parent expressing the trait, neither male nor female progeny will express the trait. You determine using molecular markers that the gene for the trait is not on the sex chromosome. What recently discovered (past 5 years or so) genetic phenomenon could explain this type of inheritance pattern? Briefly explain your answer. 10. You are studying wing shape (curled) in fruit flies and you notice you are getting odd results for the trait that you believe is under the control of a single gene. When you mate a curled wing fly with a normal wing fly you get a 1 : 1 ratio of curled to normal winged progeny. When you mate two curled winged flies you get segregation of progeny with more of the progeny having curled wings than normal wings. No matter how many curled winged flies you mate you always get progeny that segregate for curled and normal wings. What type of gene action is occurring here and briefly explain your answer. 11. You are told a trait you are studying is a recessive sex-linked trait. What type of cross or crosses would you make to test this hypothesis and what progeny would you expect from this cross or crosses if the trait was indeed a recessive sex-linked trait? 5 Name: _______________________________ 12. What are the differences between a trait under qualitative genetic control and a trait under quantitative genetic control? 6