Summary of Visit with Dr. Paz on 1/11/05
Medica Union, Colima
Patients treated with Microcyn 60:
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Started using Microcyn 14 months ago
Approximately 1,000 patients treated to date
Typical patient:
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Range of patients age (14 years to 60 years)
Have infections of the head or neck
Majority have periapical tooth root infections
Both acute and chronic infections
Majority of patients referred from other physicians
Typical treatment procedure with Microcyn 60:
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View X-rays of the patient to determine the location of the infection and treat the
patient that same visit.
Acute: If necessary, perform root canal procedure first. Then drain apical abscess
by cutting across the tooth or tissue; then apply Microcyn 60 and apply gauze at
the drain site; then flush for 2 minutes with Microcyn 60
Chronic (with fistula formation): inject Microcyn 60 slowly through the fistula
with a 10 cc syringe to flush the fistula 2 or 3 times. Takes about 3 minutes.
Post surgery has patients rinse mouth with Microcyn 3 times daily for 2 minutes.
May prescribe anti-inflammatory and analgesic medications for a few days post
surgery.
Only prescribes antibiotics if patient has signs of a systemic infection (2-3%).
Most patients are seen 1 week later and then at 90 days. More complicated cases
are rechecked more frequently.
Re-checks usually consist of evaluation of for pain and odor, signs of infection. If
the patient doesn’t have pain or odor then he assumes that the infection had
resolved. Does not typically repeat x-rays.
Previous treatment:
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Had to operate and cut the gum tissue and pull it away from the tooth and remove
all of the infected tissue (apical bone and part of the tooth) and sealed the bottom
of the tooth
Treated all localized infections with systemic antibiotics (usually for 2 to 3
weeks)
Observations:
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Every dental / non-dental / head and neck infection he has treated has been
resolved with Microcyn 60.
Microcyn must come in contact with the infected area to be effective.
Infections treated with antibiotics resolved in around 15 to 17 days.
Infections treated with Microcyn 60 resolved in 24 hours for acute infections and
2 to 5 days for chronic. Resolution is determined by a decrease in pain and odor.
Recurrence of infection in 2-3 % of patient treated with Microcyn 60 compared to
15-25% of patients treated with antibiotics.
No Microcyn related adverse events have been noted to date.
Uses Microcyn on all patients now, no contraindications noted.
Miscellaneous notes:
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Has submitted an article “Treatment of Orthodontic Infections with SuperOxidized Water” to the ADM Journal (Dental Association in Mexico) with case
reports on 4 cases (to be published in a couple of months).
Has treated infected salivary glands by injecting Microcyn 60 directly into the
salivary gland (4 sessions with 5 ccs of Microcyn 60 per session) with good
results.
Has treated herpes lesions by injecting Microcyn 60 directly into the lesion (.1 ml)
with excellent results.
Has patients use Microcyn 60 as a mouthwash 3x a day; no problems observed.
Has had good results with treating gum recession, fungal infections, stomatitis
and periodontal disease.
Has had good results with treating sinus infections and facial fractures with
infection.
He is starting a protocol soon to look at the use of Microcyn instead of antibiotics
in cancer patients with basal cell carcinoma.
Records:
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Has handwritten list for approximately last 250 patients treated with Microcyn
with sex, age, diagnosis and time to response.
Individual medical records available (not reviewed at visit).
Summary of Visit with Dr. Flores on 1/14/05:
Odontologic Integral Services
Morelia
Patients treated with Microcyn 60:
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Started using Microcyn October 7, 2003
Approximately 70 patients treated to date
Typical patient:
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50% undergoing root canal procedure
Other 50 % periodontal disease, restorations or minor oral surgery
Typical treatment procedure with Microcyn 60:
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For root canal procedure:
o Open cavity and drill root
o Inject Microcyn 60 to flush debris
o Drill root again
o Inject Microcyn 60 to irrigate root cavity (15 minute contact time) and
also use a hypodermic needle to infiltrate the soft tissue surrounding the
root with Microcyn. Note this aggressive irrigation and infiltration is
prohibited with other antiseptics due to possible damage to surrounding
tissues resulting in necrosis.
o Dry root cavity with paper and seal with a natural resin.
o Oral rinse with Microcyn for 30 days, 3 times daily for 2 minutes.
o After 30 days, oral rinse once daily indefinitely.
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For periodontal disease:
o Microcyn 60 is used for irrigation only
o Ultrasounic scaler with Microcyn to remove the smear layer
o Microcyn flush to remove debris.
o Oral rinse with Microcyn for 30 days, 3 times daily for 2 minutes.
o After 30 days, oral rinse once daily indefinitely.
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For cavities:
o Uses Microcyn 60 as coolant with handpiece to eliminate post op damage
to pulp tissue
o Acid added 34 to 37% for 15 to 20 seconds
o Rinse with Microcyn 60
o Polymerize with adhesives
o Fill cavity with acrylic
o Polish tooth
Previous treatment:
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Used saline or water for flushes and as coolant for handpiece and ultrasonic
scaler.
For root canals irrigated with sodium hypochlorite 2.5% solution which is very
irritating and cannot contact surrounding soft tissue due to potential for necrosis.
For periodontal disease used mouthwash (0.012% chlorhexidine solution) 2x a
day and flossing. Chlorhexidine can only be used for a limited number of days
(15 days) without causing side effects and it is only bacterialcidal (not a
sporocidal or fungicidal)
Observations:
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In root canals, lesion resolves in about 5 days with Microcyn. Typical takes 4 to 6
months with antiseptics.
In cases with periodontal disease, regeneration of gum tissue within 15 days. In
first Microcyn periodontal patient pocket went from 6mm to 1.5mm on probe.
Pain resolves within 24 hours. Patients can chew within 24 hrs, used to take 72
hrs.
With Microcyn use no longer prescribes antibiotic, anti-inflammatory or analgesic
medications. Used to prescribe with all procedures.
Tastes better than chlorhexidine.
When using Microcyn 60 have better hemostasis and less bleeding.
Some patients experience a slight burning sensation on the tongue when gargling;
he instructs them to spit out the solution. The burning then dissipates
Uses Microcyn on all patients now, no contraindications noted.
Miscellaneous notes:
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Uses Microcyn 60 as a flush and coolant solution for the handpiece and with the
ultrasonic scaler in all procedures.
Disinfects his equipment with Microcyn 60.
Disinfects office hard surfaces with Microcyn.
Oral rinse with Microcyn 60 is prescribed for every patient, once daily
indefinately.
Herpes lesions resolve within 4 days.
Has done a study involving 20 patients treated with Microcyn (all having a
similar lesions and no antibiotic treatment) – 40% resolved in 4 to 6 months due
to the process of instrumentation – the foramen was sealed so Microcyn 60 could
not enter – the other 60% resolved in 5 to 25 days because Microcyn could
infiltrate the infected area.
Records:
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Has good quality individual medical records available on patients including
photographs, x-rays and dental probe data.