CHNOPS 1
Simulating Protein Synthesis
A CHNOP is a fictitious organism that only has one chromosome. On this chromosomes
are 8 different genes. Each box represents one gene. All the boxes represent one
chromosome. For each gene transcribe the DNA into mRNA. Then translate the mRNA
into a protein. For this activity each protein is being represented by a numeric
sequence. Certain sequences tell you what trait to give your CHNOP (example—one
box (gene) makes a protein that controls skin color)
DNA
ACC GGT TAT
DNA
AGC TTT
DNA
TTT AAC
mRNA: _________________________
mRNA: _________________________
mRNA: ________________________
amino acid
sequence:
__________________________________
__________________________________
amino acid
sequence:
_______________________________
_______________________________
amino acid
sequence:
______________________________
______________________________
trait: _____________________________
trait: ___________________________
trait: ___________________________
DNA
DNA
DNA
GGA CGC CGA
GGG AGG AAA CCC
ACC GAA GAA
mRNA: _________________________
mRNA: _________________________
mRNA: ________________________
amino acid
sequence:
________________________________
________________________________
amino acid
sequence:
________________________________
________________________________
amino acid
sequence:
_______________________________
_______________________________
trait: _____________________________
trait: ___________________________
trait: ___________________________
DNA
DNA
GGG CGA ACC GGA
CCC AGG AGC
mRNA: _________________________
mRNA: ________________________
amino acid
sequence:
__________________________________
__________________________________
amino acid
sequence:
______________________________
______________________________
trait: ___________________________
trait: ___________________________
Draw your CHNOP on a sheet of white paper
CHNOPS
1. Explain the difference between translation and transcription.
2. Where is the specific site for transcription?
3. Where is the specific site for translation?
4. Suppose you knew the order of amino acids in a protein. How would you
determine the order of the DNA for that protein?
5. How could a change in one nitrogen base alter a protein?
CLASS SET
AMINO ACID CHART
Amino Acid Sequence
Tryptophan-ProlineIsoleucine
Tryptophan-ProlineHistidine
Tryptophan-LeucineLeucine
Isoleucine-ArginineThreonine
Serine-Lysine
Aspartic Acid-Serine
Proline-SerinePhenylalanine-Glycine
Proline-Valine-TyrosineGylcine
Lysine-Phenylalanine
Lysine-Leucine
Glycine-Phenylalanine
Cytesine-Stop
Proline-AlanineAlanine
Proline-Serine-Serine
Proline-Alanine-Lysine
Proline-ArginineArginine
Tyrosine-TyrosineAspartic Acid
Tyrosine-TyrosineHistidine
Proline-AlanineTryptophan-Proline
Proline-Leucine-SerineProline
Proline-AlanineLeucine-Proline
Glycine-Serine-Serine
Glycine-AlanineAspartic Acid
Glycine-Serine-Alanine
Trait
Hairless
Hairy
Plump
Skinny
Four-legged
Six-legged
Long nose
Short nose
No freckles
Freckles
Dimples
Birthmark
Blue skin
Orange skin
Green skin
Purple skin
Male
Female
One tooth
Three teeth
Lots of teeth
Bushy monobrow
Thin eyebrow
No eyebrows