FP7 Regions of Knowledge – Biotech/Medical devices North East England, UK The information below summarizes the ‘offer’ of our triple helix regional partnership which reflects the breath of expertise and delivery which are highly relevant to the RoK healthcare research driven cluster call within the North East of England region. All regional partners have an extensive track record of leading and partnering within a wide range of EU funded projects and can offer a wide range of dissemination networks and deliver regional, national and European level policy influence. Proposed Offer North East England could contribute to a RoK bid around health and wellbeing, with a targeted focus on sub themes of ageing (assisted living ) and telehealth. A schematic of the areas which could be included are as follows: Health and Wellbeing Commercial activities Research Gerontology Health monitoring Imaging biomarkers Telehealth Production and sales IT & Device Design The above encapsulates current research and commercial activities in development in North East England. This regional cross-sector activity is focussed on areas of ageing research, biomarker discovery and their various contributions in projects and emerging commercial applications within community based monitoring of elderly and patients with chronic illness. Regional academic expertise Newcastle University: The University has developed a theme, ‘Technology for an Ageing Population’ which is focused on the development, evaluation and implementation of the devices, tools and technologies that facilitate healthy ageing and lifelong vitality and promote independent living as people grow older. The theme brings together academia, health care and industry to accelerate translation of technology from laboratory to hospital and community care. The Institute for Ageing and Health acts as a springboard around which to base this initiative, giving focus and credibility to a disparate group of technologies and personalities who can work together to develop this growing area of technology. The Newcastle Brain Tissue Resource (NBTR) is run as a partnership between the Medical Research Council (MRC), local NHS trusts and Newcastle University. The bank has been developed over the past 30 years and contains a well-characterised collection of fixed and frozen post-mortem material. Material includes post-mortem tissue from both healthy elderly patients and from patients suffering from brain disorders such as Alzheimer’s disease, dementia with Lewy bodies, Parkinson’s disease, vascular dementia, motor neuron disease and major depression. Regional approach to engagement with national and international industry: Cels has taken a regional lead in developing strategic links with major technology providers on an International basis. These providers are directly involved in the area of assistive technology targeting the ageing population and or developing strategies to engage with the various market opportunities. The region has connections to the member of the Continua Alliance, a non profit open international industry alliance of the finest healthcare and technology companies collaborating to improve the quality of personal healthcare. The mission of Continua is to establish a system of interoperable health systems to empower people, and organizations, to manage their own health and wellbeing. Continua has numerous members, with notable names such as IBM, Bayer, Pfizer, Nokia and GE Healthcare. Local engagement with industry: The region has a number of SME’s who are engaged in a variety of telehealth and assisted living projects. These companies have been identified and are given assistance where required or maintained in contact by the University or Cels network HealthConnect or Science City, to help develop products and services , raise their activity profile and increase their regional knowledge awareness as to the market opportunity in this emerging sector. Regional engagement with EU and international initiatives:The region as represented by Cels joined the AALIANCE network, a co-ordinated action funded by EU 7th Framework which commenced in January 2008. AALIANCE provides a framework for stakeholders, led by industry, to define research and development priorities, timeframes, and action plans on strategically important issues in Ambient Assisted Living (AAL). The project’s is set up to develop a sustainable network of technology providers and systems integrators, service providers, research organisations and end user associations. This network of expertise is preparing and maintaining a Research and Technology Development (RTD) roadmap and strategic research agenda for AAL over the medium to long term. From the above short description of the regions activities and expertise in this area there is a clear offer of a broad capability in academic research of ageing and the translation of this activity into products and services which can be implemented into the marketplace in the short and medium term. A clear opportunity now exists to share and expand this knowledge using a triple helix approach to accelerate activity and realise significant progress in this highly important area. North East of England Triple-helix Partnership One North East – is one of nine English Regional Development Agencies (RDA) responsible for the economic development of North East England and delivery of the Regional Economic Strategy (RES). One is also responsible for the management and delivery of the regional ERDF Programme, has been involved as a partner within RoK before (ARRGOS project, FP6) and has an established track record both as lead and partner in a range of successful Interreg and FP6/7 projects as the below map illustrates: As demonstrated in the diagram below, healthcare and health sciences are strongly embedded as one of the ‘three pillars’ of our RES due to the potential the region has to develop long term economic competitiveness within this sector: Way Forward Summary Healthcare & Health Sciences Centre for Enabling Technology (Cenamps) Design Energy & Environment Process Innovation Private Finance Science & Industry Council Physical Centres E-Business (Codeworks) Management Skills NStar Universities Science City/ City Regions Cels (The Centre of Excellence for Life Sciences Ltd) - is partly funded by One North East to drive the growth of the healthcare and life sciences economy of North East England. Cels is committed to developing scientific enterprise through development and commercialisation of new technology, innovations and the exploitation of new and emerging market opportunities. Cels drives growth in four main ways: By building and managing first-class business and research infrastructure By placing the region on the world stage through internationally recognised networks By managing emerging technology and stimulating the formation of new business ventures By offering business start-ups management and financial assistance. In order to achieve this, Cels works in close partnership with the North East’s regional universities, associated research institutes, healthcare and life science companies and public sector organisations. Specifically, Cels: Supports the region’s existing and new healthcare and life sciences companies Attracts inward investment and new healthcare companies to the region Helps companies diversify into healthcare markets Sits at the hub of a global network of healthcare and bio clusters Manages a regional networks for R&D and inter-company collaboration (HealthConnect) Develops and operates business incubator and bio-park facilities Provides a range of commercial foresighting and business support services The North East has a growing and dynamic industrial base that spans from multinational pharmaceutical companies to innovative spin outs and start-ups in areas such as oncology and regenerative medicine. Cels activity is focused on supporting partners in the following key subsectors: Stem Cells and Regenerative Medicine Ageing and Health (including Assistive Technology) Drug Discovery and Biomarkers Diagnostics and Medical Devices Biopharmaceutical Process Development Cels aim is to support and bring together the strengths of the region’s research, clinical and industrial expertise and create a compelling environment for business development and growth. Newcastle Science City - in December 2004, Newcastle was designated as one of six English Science Cities by the UK Government. The Science Cities were tasked with leading the development of deeper links between business and the science base, and to ensure that science, technology and innovation succeed in becoming the engine of economic growth. Newcastle Science City has made great headway in its ambition to enhance prosperity from science for Newcastle. In 2005, Newcastle City Council, Newcastle University and One North East formed a triple-helix partnership to develop the strategic vision and objectives of Newcastle as a world class Science City, as it plays a key part in their respective ambitions and strategies. Newcastle University – is in the top 3 of UK Universities accessing FP funding for research and is also linked to the Institute for Ageing and Health, based at the Campus for Ageing and Vitality on the Newcastle General Hospital site. The institute is unique in bringing together biological, clinical and social scientists from across the region with NHS services for old age medicine and psychiatry. Already recognised as Europe’s leading centre for research related to ageing, it is well placed to capitalise on the extensive commercialisation opportunities available and to deliver significant economic/social benefits. Opportunities include the identification and/or the development of: New understanding of the fundamental mechanisms underpinning agerelated frailty, disability and disease that will offer novel routes to intervene in these processes. Biomarkers of ageing that can be used to monitor the impact of new interventions (basic science). New models of health care delivery through the NHS and health care industry (clinical science). Novel assistive technologies that promote independent living, create new market opportunities and reduce the cost of care (technology). Comprehensive clinical and pre-clinical imaging resources that together with existing world-class technical and research expertise in radiochemistry, medical physics and imaging methodology, will facilitate clinical and translational research in age-related diseases, including cancer (scientific techniques). The Ageing and Health theme within Newcastle Science City offers disruptive approaches to meeting what is recognised globally as one of the greatest challenges (and opportunities) confronting humanity in the 21st century. Emma Harvey Transnational Development Senior Specialist One North East, 25th September 2009