Biology 303
Instructor:
Fundamental Genetics, Sect. 001
Dr. Alan S. Waldman
Fall, 2009
CLS rm 309 (7-8405)
MWF 10:10- 11:00AM
Office Hours: MW 2:30-3:30
Room: CLS 005
(or by appointment)
Course Website on Blackboard
awaldman@biol.sc.edu
------------------------------------------------------------------------------------------------------Required Text: Klug, Cummings, Spencer, and Palladino Concepts of Genetics, Ninth Edition,
Pearson/Benjamin Cummings.
------------------------------------------------------------------------------------------------------Tentative Course Schedule (Most recent update: 10/14/09)
Date:
Topic:
8/21
8/24
8/26
8/28
8/31
9/2
9/4
9/7
9/9
9/11
9/14
9/16
9/18
9/21
9/23
9/25
9/28
9/30
10/2
10/5
10/7
10/9
10/12
10/14
10/16
10/19
10/21
10/23
10/26
10/28
10/30
11/2
11/4
11/6
11/9
Course overview
Mitosis & Meiosis
Mendelian Genetics
Mendelian Genetics
Mendelian Genetics
Extension of Mendelian Genetics
Think Genetics It’s Friday (TGIF)*
Labor Day!
Extension of Mendelian Genetics
Chromosome Mapping in Eukaryotes
Chromosome Mapping in Eukaryotes
Chromosome Mapping in Eukaryotes
Chromosome Mapping in Eukaryotes/Sex Determination …
EXAM I
Sex Determination and Sex Chromosomes
TGIF
No class
Chromosome Mutations
Chromosome Mutations
DNA Structure and Analysis
DNA Structure and Analysis
Fall Break!
DNA Replication
DNA Organizaion in Chromosomes
Gene Mutation and DNA Repair
Gene Mutation and DNA Repair
Gene Mutation and DNA Repair/Transposons
The Genetic Code and Transcription
EXAM II
The Genetic Code and Transcription
Regulation of Gene Expression in Prokaryotes
Regulation of Gene Expression in Eukaryotes
Regulation of Gene Expression in Eukaryotes
TGIF
Cancer and Regulation of the Cell Cycle
Chapter:
2
3
3
3
4
4
5
5
5
5,7
7
8
8
10
10
11
12
16
16
16,22
14
14
17
18
18
20
11/11
11/13
11/16
11/18
11/20
11/23
11/25
11/27
11/30
12/2
12/4
12/8
Recombinant DNA Technology & Gene Cloning
TGIF
Genomics, Bioinformatics, and Proteomics
Genomics, Bioinformatics, and Proteomics
Genomics, Bioinformatics, and Proteomics
EXAM III
Thanksgiving!
Thanksgiving!
Applications and Ethics of Genetic Engineering and
Biotechnology
Applications and Ethics of Genetic Engineering and
Biotechnology
Catch-up
FINAL EXAM, 9:00 AM (Comprehensive)
13
21
21
21
24
24
*
TGIF refers to special reading or other exercises that will be assigned.
Learning Outcomes
By the end of the term, successful students should have gained a fundamental knowledge of both
classical (Mendelian) and molecular genetics. This knowledge will include an understanding of
• how genetic traits are transmitted.
•
how to predict the expected types and probabilities of particular genotypes and
phenotypes among offspring of genetic crosses.
•
DNA structure and how it may be altered by mutation.
•
gene mapping.
•
chromosome and genome structure.
•
how gene expression may be regulated.
•
the fundamentals of cancer biology.
•
the basics of biotechnology and related issues.