UNIVERSITY OF FLORIDA
COLLEGE OF NURSING
COURSE SYLLABUS
Fall 2012
COURSE NUMBER
NGR 6930sect 14d3, 14d4
COURSE TITLE
CREDITS
Genomics in Health Care
3
PLACEMENT
Elective
PREREQUISITES
NGR 6002C Advanced Health Assessment and Diagnostic
Reasoning
NGR 6140 Physiology and Pathophysiology for Advanced
Nursing Practice
NGR 6192 Pharmacotherapeutics for Advance Practice
Nursing
COREQUISITES
None
FACULTY
Rose M. Nealis, PhD, ARNP,
ACPNP, PNP-BC
nealirm@ ufl.edu
Jacqui Hoffman, DNP, ARNP, NNP-BC
NNP Clinical Track Coordinator
Clinical Assistant Professor
hoffmanjm@ufl.edu
DEPARTMENT CHAIR
Susan Schaffer, PhD, ARNP,
FNP-BC
Clinical Associate Professor
sdschaf@ufl.edu
HPNP 2220
(352)273-6412
Monday 1-3 pm
or by appointment
(727) 709-9211
HPNP 2229
Office 352-273-6366
Monday 11:30-1:30
JACKSONVILLE CAMPUS DIRECTOR
Andrea C. Gregg, DSN, RN Jacksonville Campus
greggac@nursing.ufl.edu
Ofc#: 904-244-5172
By Appointment
COURSE DESCRIPTION
The course is designed build on the advance practice nursing skills while incorporating concepts and
principles of genetic/genomics to clinical nursing phenomena. Using case-based methodology, students
will be asked to integrate the concepts and principles of genetics, genetic testing, genetic diseases, and
evaluate the strengths and limitations of genetic therapies. Ethical, legal, and clinical practice issues
and perspectives, including, but not limited to bias, will be covered.
COURSE OBJECTIVES
Upon completion of the course, the student will:
1.
Integrate the concepts and principles genetics/genomics to identified clinical cases
utilizing genetic/genomic terminology
2.
Construct and analyze a family pedigree utilizing the recognized pedigree symbols to
analyze patterns of inheritance .
3.
Discuss the application and implication of genetic testing in identified populations.
4.
Discuss the limitations of gene therapies in selected patient populations.
5.
Incorporate Ethical, legal and clinical practice issues in to selected clinical cases.
6.
Discuss the role of the health care providers in the management of genetic disorders.
COURSE SCHEDULE Web Based
E-Learning is the course management system that you will use for this course. E-Learning is
accessed by using your Gatorlink account name and password at http://lss.at.ufl.edu. There are
several tutorials and student help links on the E-Learning login site. If you have technical questions
call the UF Computer Help Desk at 352-392-HELP or send email to helpdesk@ufl.edu.
It is important that you regularly check your Gatorlink account email for College and
University wide information and the course E-Learning site for announcements and notifications.
Course websites are generally made available on the Friday before the first day of classes.
ATTENDANCE: . Students are responsible for responding to online assignments as part of their
attendance. Timeframes for the posting and receiving of materials are listed in the course materials on the
course web-site. Students may expect to receive feedback regarding submitted assignments within 2 weeks,
barring unforeseen circumstances. A grade penalty 0f 10%/day will be assigned for late assignments. Students
are responsible for responding to online assignments as part of their attendance.
ACCOMMODATIONS DUE TO DISABILITY:
Each semester, students are responsible for requesting a memorandum from the Disability Resource
Center to notify faculty of their requested individual accommodations. This should be done at the
start of the semester.
STUDENT HANDBOOK:
Students are to refer to the College of Nursing Student Handbook for information about College of
Nursing student policies, honor code, and professional behavior. Of particular importance for this
course are the sections on appearance in clinical practice, personal liability insurance, and student
safety.
ACADEMIC HONESTY
The University of Florida Student Conduct and Conflict Resolution Policy may be found at
http://www.dso.ufl.edu/sccr/honorcode.php
UNIVERSTY COUNSELING AND MENTAL HEALTH SERVICES
http://www.counseling.ufl.edu/cwc/
TOPICAL OUTLINE
1.
Human Genome Project
2.
Genetic Biology
3.
Interpreting Family History
4.
Genetic Referrals
5.
Genetic Testing
6.
Ethical, Legal and Societal Issues
7.
Pharmacogenomics/Pharmacogenetics
8.
Environmental Genetics and Complex disease
9.
Role of health Care Providers in Genomics
TEACHING METHODS: Self paced modules,
LEARNING ACTIVITIES: On-line modules,
EVALUATION METHODS/COURSE GRADE CALCULATION
Module Completion. Pedigree Construction
GRADING SCALE
A
94-100
C
B+
92- 93
D+
B
84-91
D
C+
82-83
E
* 74 is the minimal passing grade
74-81*
72-73
64-71
63 or below
REQUIRED TEXTS
Genetics Education Program for Nurses, University of Cincinnati modules.
complete the free multimedia resources first.
Click
http://www.cincinnatichildrens.org/education/clinical/nursing/genetics/cont/self/default/ Order the 4
independent self paced modules.
Learning Activities: Complete the following activities:
Go to the following sites and complete the readings and or activities:
Genetics Education Program for Nurses, University of Cincinnati modules.
Click
http://www.cincinnatichildrens.org/education/clinical/nursing/genetics/instruction/default/
complete the free multimedia resources first.
Free Multimedia Instructional Resources
Chromosome, DNA, Gene Presentation - The objective of this audio slide presentation is to help
nurses distinguish between the terms chromosome, DNA and gene.
Genetics is Relevant Now: Nurses’ Views and Patient Stories - The purpose of this resource is to
inform nurses about the relevance of genetics and genomics in patient care and nursing practice.
Introduction to Genetic Counseling - The objective of this audio slide presentation is to increase
awareness about the role of genetic counselors and how they interact with other health care
professionals.
Mendelian Inheritance - Meiosis Connection -- The purpose of this interactive, audio FLASH
presentation is to demonstrate the basic relationship between Meiosis and Mendelian Inheritance.
Multiple Roles of Genetics Nurses -- The objective of this audio slide presentation is to increase
awareness about the practice, education, research and administration roles of genetics nurses.
Perspectives on Genetic Conditions - Sharing the Journey Video Clips - A compilation of video clips
from 3 of the 5 Consumer Panels hosted during the Genetics Summer Institutes at Cincinnati
Children’s Hospital Medical Center are presented. The panels, from which the video clips were
extracted, were taped in 1998, 2001 and 2003. Use of these clips requires a registration and log on
Click on
http://www.cincinnatichildrens.org/education/clinical/nursing/genetics/cont/self/default/
Order the 4 independent self paced modules.
Interpreting Family History Self-Paced Module (login link for PC & Mac users)
This module is designed to enable the learner interpret family history information to identify and refer
clients who can benefit from genetic services. Nurses who complete the entire module and related
evaluation will be awarded 5.8 nursing contact hours.
Ethical and Social Issues Related to Genetic Testing Self-Paced Module (login link for PC & Mac
users)
This module is designed to help the learner identify ethical and social issues related to genetic testing
and recording of genetic information. Nurses who complete the entire module and related evaluation
will be awarded 4.7 nursing contact hours.
Nurses’ Role in Pharmacogenetics / Pharmacogenomics (login link for PC & Mac users)
This module is designed to enable the learner to help patients understand the purpose and limitations of
pharmacogenetics testing and the implications of their test results. Nurses who complete the entire
module and related evaluation will be awarded 4.3 nursing contact hours.
Promoting Informed Decision Making about Genetic Testing (login link for PC & Mac users)
This module is designed to help the learner promote a person’s / family’s ability to make an informed
decision about genetic testing. Nurses who complete the entire module and related evaluation will be
awarded 5.8 nursing contact hours
Each module is $15
You must submit your certificate with Test Scores in the Course Drop-Box.
March of Dimes Genetics and Your Practice http://www.marchofdimes.com/gyponline/index.bm2.
You will need to register at this site. Take the Self Assessment Quiz, Complete the modules Genetic
Testing and Screening, Family Health and Social History, Referral, Complete the Case study at the end
of each module.
Genetics in the Physician Assistant’s Practice http://www.nchpeg.org/pa/
Complete the Case study on Stephanie Henderson or Andrew Johnson , The Genetics Primer and the
Family History Exercises, Also read the material on Genetic Testing
Construct a 3-generation pedigree using the posted case study data
Evaluation: Complete Genetics Education Program for Nurses, University of Cincinnati modules.
With a grade of 90 or higher. Turn in Certificates 60%
Complete march of dimes Modules- Turn in Pretest and Post Test 10%
Complete the Genetics in the Physician Assistant’s Practice 10%
Submitted 3 generation pedigree. Using correct symbols and interpretation. 10%
Paper on application of Genetics to Practice 10%
March of Dimes Genetics and Your Practice http://www.marchofdimes.com/gyponline/index.bm2.
You will need to register at this site. Take the Self Assessment Quiz, Complete the modules Genetic
Testing and Screening, Family Health and Social History, Referral, Complete the Case study at the end
of each module.
Nussbaum, R.L., McInnes, R. R. & Willard, H. F. (2007) Thompson & Thompson Genetics in
Medicine: With STUDENT CONSULT Online Access (GENETICS IN MEDICINE).Philadelphia: W.
B. Saunders
Web based Assignments:
http://www.marchofdimes.com/gyponline/index.bm2
http://www.genome.gov/27527634
http://www.cancer.gov/cancertopics/understandingcancer/genetesting/
http://www.cancer.gov/cancertopics/prevention-genetics-causes/genetics
http://www.cancer.gov/cancertopics/pdq/genetics/risk-assessment-andcounseling/healthprofessional#Section_2
http://learn.genetics.utah.edu/units/pharma/phmedcare/Latrice.
RECOMMENDED TEXTS : None
WEEKLY CLASS SCHEDULE : You may work at your own pace, I have attached a schedule to keep
you on Track.
DATE
Week of
8/22/12
TOPIC/EVALUATI
ON
Self Assessment of
Genetic Knowledge
ASSIGNMENTS/READINGS
http://www.marchofdimes.com/gyponline/index.bm2
Genetic Competencies: http://www.genome.gov/27527634
Genetics Is Relevant Now
http://www.cincinnatichildrens.org/ed/clinical/gpnf/resources/curriculum/releva
nt-genetics.htm
Human Genome
http://www.ornl.gov/sci/techresources/Human_Genome/home.shtml
8/29/12
Genetics Tutorial Chromosomes and DNA
http://www.cincinnatichildrens.org/ed/clinical/gpnf/resources/curriculum/chro
mosome.htm
9/5/12
Genetic Biology
Neoplasia http://www.cancer.gov/cancertopics/understandingcancer/cancer
Meiosishttp://www.cincinnatichildrens.org/ed/clinical/gpnf/resources/curriculum/mend
elian.htm
9/12/12
Genetic Biology
Cardiovascular Relevance of Genetics and Genomics for the Treatment and
Prevention of Cardiovascular Disease
http://circ.ahajournals.org/cgi/content/full/115/22/2878
FACULT
Y
Nealis
9/19/12
Genetic Testing
Understanding Genetic Testing:
Genetics in the Physician Assistant’s Practice
http://www.nchpeg.org/pa/
Genetic Testing and Screening in Your practice
http://www.marchofdimes.com/gyponline/index.bm2
9/26/12
Genetic Testing
Genetic Testing University of Cincinnati Module
10/3/12
Pharmacogenetics
University of Cincinnati Module
10/10/12
Family History
University of Cincinnati Module
CDC- http://www.cdc.gov/genomics/fhix.htm
Genetics in the Physician Assistant’s Practice
http://www.nchpeg.org/pa/
10/17/12
Genetic Counseling
http://www.cincinnatichildrens.org/ed/clinical/gpnf/resources/curriculum/geneti
c-counseling.htm
10/24/12
Ethics and Social
Policy
Ethics and Social Policyhttp://www.genome.gov/page.cfm?pageID=10001618
Informed Decision Making – University of Cincinnati Module
10/31/12
Ethics and Social
Policy
Information for Researchers and Health Care Professionals
GINA : http://www.genome.gov/24519851/
University of Cincinnati Module
11/6/12
Environmental
Genetics
University of Cincinnati Module
11/13/12
Public Health
Genomics
EGAPP/CDC Cardiovascular Health: Genomic profiling to assess
cardiovascular risk to improve cardiovascular health
http://www.egappreviews.org/
11/20/12
Genetic Referrals
March of Dimes http://www.marchofdimes.com/gyponline/index.bm2
11/27/12
Role of Health Care
Providers
Gene Clinics http://www.genetests.org/
!2/4/12
Genetics in the Physician Assistant’s Practice
http://www.nchpeg.org/pa/
All Certificates, Genograms and Paper are due by 5pm. EST
References:
American Society of Human Genetics
Medical School Core Curriculum in Genetics
Jenkins, J. F., Dimond, E., & Steinberg, S. (2001). Preparing for the future through genetics nursing
education. Journal of Nursing Scholarship, 33(2), 191-195.
Jenkins, J.F., Prows, C., Dimond, E., Monsen, R. & Williams, J. (2001). Recommendations for
Educating Nurses in Genetics. Journal of Professional Nursing, 17(6), 283-290.
American Society of Human Genetics
Medical School Core Curriculum in Genetics
Genomic Competencies for the Public Health Workforce
Genomics Workforce Competencies 2001
National Coalition of Health Care Professionals' Education in Genetics
Core Competencies in Genetics Essential for All Health-Care Professionals
Approved:
Academic Affairs Committee 2008
Faculty 2008
UF Curriculum 2008