EASO 2011 Awards – Granado Publication List 1: Granado M, García-Cáceres C, Frago LM, Argente J, Chowen JA. The positive effects of growth hormone-releasing peptide-6 on weight gain and fat mass accrual depend on the insulin/glucose status. Endocrinology. 2010 May;151(5):2008-18. Epub 2010 Mar 10. PubMed PMID: 20219977. 2: Granado M, Chowen JA, García-Cáceres C, Delgado-Rubín A, Barrios V, Castillero E, Argente J, Frago LM. Ghrelin treatment protects lactotrophs from apoptosis in the pituitary of diabetic rats. Mol Cell Endocrinol. 2009 Oct 15;309(1-2):67-75. Epub 2009 Jun 18. PubMed PMID: 19540304. 3: Castillero E, Martín AI, López-Menduiña M, Granado M, Villanúa MA, López-Calderón A. IGF-I system, atrogenes and myogenic regulatory factors in arthritis induced muscle wasting. Mol Cell Endocrinol. 2009 Oct 15;309(1-2):8-16. Epub 2009 Jun 6. PubMed PMID: 19501629. 4: Granado M, Martín AI, Castillero E, López-Calderón A, Villanúa MA. Cyclooxygenase-2 inhibition reverts the decrease in adiponectin levels and attenuates the loss of white adipose tissue during chronic inflammation. Eur J Pharmacol. 2009 Apr 17;608(1-3):97-103. Epub 2009 Feb 23. PubMed PMID: 19239908. 5: Martín AI, López-Menduiña M, Castillero E, Granado M, Villanúa MA, López-Calderón A. Cyclooxygenase-2 [corrected] activation by endotoxin mediates the decrease in IGF1, but not in IGFBP3, [corrected] gene expression in the liver. J Endocrinol. 2008 Aug;198(2):385-94. Epub 2008 May 20. Erratum in: J Endocrinol. 2008 Dec;199(3):501. PubMed PMID: 18492809. 6: Martín AI, Castillero E, Granado M, López-Menduiña M, Villanúa MA, López-Calderón A. Adipose tissue loss in adjuvant arthritis is associated with a decrease in lipogenesis, but not with an increase in lipolysis. J Endocrinol.2008 Apr;197(1):111-9. PubMed PMID: 18372237. 7: Granado M, Martín AI, López-Menduiña M, López-Calderón A, Villanúa MA. GH-releasing peptide-2 administration prevents liver inflammatory response in endotoxemia. Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E131-41. Epub 2007 Nov 6. PubMed PMID: 17986630. 8: Granado M, Martín AI, Villanúa MA, López-Calderón A. Experimental arthritis inhibits the insulin-like growth factor-I axis and induces muscle wasting through cyclooxygenase-2 activation. Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1656-65. Epub 2007 Feb 6. PubMed PMID: 17284570. 9: Granado M, Martín AI, Priego T, López-Calderón A, Villanúa MA. Tumour necrosis factor blockade did not prevent the increase of muscular muscle RING finger-1 and muscle atrophy F-box in arthritic rats. J Endocrinol. 2006 Oct;191(1):319-26. PubMed PMID: 17065414. 10: Priego T, Granado M, Castillero E, Martín AI, Villanúa MA, López-Calderón A. Nitric oxide production by hepatocytes contributes to the inhibitory effect of endotoxin on insulin-like growth factor I gene expression. J Endocrinol. 2006 Sep;190(3):847-56. PubMed PMID: 17003285. 11: Granado M, Priego T, Martín AI, Vara E, López-Calderón A, Angeles Villanúa M. Anti-tumor necrosis factor agent PEG-sTNFRI improves the growth hormone/insulin-like growth factor-I system in adjuvant-induced arthritic rats. Eur J Pharmacol. 2006 Apr 24;536(1-2):204-10. Epub 2006 Mar 2. PubMed PMID: 16545800. 12: Granado M, Martín AI, Priego T, Villanúa MA, López-Calderón A. Inactivation of Kupffer cells by gadolinium administration prevents lipopolysaccharide-induced decrease in liver insulin-like growth factor-I and IGF-binding protein-3 gene expression. J Endocrinol. 2006 Mar;188(3):503-11. PubMed PMID: 16522730. 13: Granado M, Priego T, Martín AI, Villanúa MA, López-Calderón A. Ghrelin receptor agonist GHRP-2 prevents arthritis-induced increase in E3 ubiquitin-ligating enzymes MuRF1 and MAFbx gene expression in skeletal muscle. Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E1007-14. Epub 2005 Jul 19. PubMed PMID: 16030067. 14: Priego T, Granado M, Martín AI, López-Calderón A, Villanúa MA. Dexamethasone administration attenuates the inhibitory effect of lipopolysaccharide on IGF-I and IGF-binding protein-3 in adult rats. J Endocrinol. 2005 Jun;185(3):467-76. PubMed PMID: 15930173. 15: Granado M, Priego T, Martín AI, Villanúa MA, López-Calderón A. Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats. Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E486-92. Epub 2004 Oct 26. PubMed PMID: 15507538. 16: Ibáñez de Cáceres I, Priego T, Martín AI, Granado M, López-Calderón A, Villanúa MA. Effect of inducible nitric oxide synthase inhibition by aminoguanidine on insulin-like growth factor binding protein-3 in adjuvant-induced arthritic rats. Eur J Pharmacol. 2003 Nov 28;481(2-3):293-9. PubMed PMID: 14642797. 17: Priego T, Granado M, Ibáñez de Cáceres I, Martín AI, Villanúa MA, López-Calderón A. Endotoxin at low doses stimulates pituitary GH whereas it decreases IGF-I and IGF-binding protein-3 in rats. J Endocrinol. 2003 Oct;179(1):107-17. PubMed PMID: 14529571.