SINGLE STAGED MASTOPEXY WITH AUTOLOGOUS FAT GRAFTING Kamran Khoobehi MD, Alireza Sadeghi MD Abstract: Background: Numerous techniques for correction of mammary ptosis have been described. However, the majority of women requiring mastopexy require some degree of volume augmentation to compensate for mammary atrophy. The concept of a single stage mastopexy with prosthetic implant augmentation is an attractive concept, but is known to have higher rates of complications and frequent need for revisions. Furthermore, superior pole fullness is usually lacking in majority of patients undergoing this procedure and postoperative "bottoming out" of the implant is a common long term problem. Utilizing autologous fat grafting as a means of augmenting volume, creating an attractive cleavage and providing superior pole fullness to the breasts at the time of mastopexy is a viable alternative. Methods: A retrospective review of 89 autologous fat transfers to the breasts in 46 patients from October 2006 to March 2009 was performed. Procedures included mastopexy and autologous fat grafting with or without implant removal. Pre- and postoperative photography and mammography were performed. Results: The mean follow-up period of patients was 12.5 months. With the exception of one patient, all patients with postoperative mammograms were clear of any abnormalities in comparison to preoperative mammograms. All women had a significant improvement in their breast size and shape postoperatively and all had breasts that were soft and natural in feel and appearance without evidence of fat necrosis (Figure 1). Mean operative time of mastopexy and fat grafting to the breast was 154.7 minutes (Table 1). Conclusion: Single staged mastopexy with autologous fat grafting to correct breast ptosis with restoration of volume is an alternative in breast rejuvenation. This single staged technique provides superior pole fullness of the breast and an attractive cleavage without disturbing the circulation to the breast and the architecture of the breast. Therefore, by eliminating the use of prosthesis it reduces the rates of complications seen with mastopexy and simultaneous implant augmentation. REFERENCES: 1. Yoshimura K, Sato K, Aoi N, Kurita M, Hirohi T, Harii K. Cell-Assisted Lipotransfer for Cosmetic Breast Augmentation: Supporive Use of Adipose-Derived Stem/Stromal Cells. Aesth Plast Surg 2008; 32:48-55. 2. Yushimura K, Suga H, Eto H. Adipose-dreived stem/progenitor cells: roles in adipose tissue remodeling and potential use for soft tissue augmentation. Regen Med 2009; 4(2) 1-9. 3. Rohrich RJ, Thornton JF, Jakubietz RG, Jakubietz MG, Grunert JG. The limited scar mastopexy: Current concepts and approches to correct breast ptosis. Plast Reconst Surg 2004; 114: 1622-1630. 4. Spear SL, Boehmler JH, Clemens MW. Augmentation/Mastopexy: A 3-year review of a single surgeon’s practice. Plast Reconstr Surg 2006; 118: 136S-147S. 5. Coleman SR, Saboeiro AP. Fat grafting to the breast revisited: Safety and Efficacy. Plast Reconstr Surg 2007; 119:775-785. DISCLOSURES: None of the authors has a financial interest in any of the products, devices, or drugs mentioned in this manuscript Figure 1. 30 year old female with a 9 month follow up after undergoing an abdominoplasty and single staged mastopexy with autologous fat grafting of 710 cc to each breast. Patient Demographics Patients Breasts Mastopexy only Mastopexy & Implant removal Age (Mean) BMI (Mean) Operative Time (minutes) Amount Fat Graft (cc) Right Breast Left Breast Follow Up (months) Grade of Ptosis 46 89 34 12 19 - 66 (39.6 ± 10.3) 19.5 - 35.4 (24.8 ± 4.0) 95 - 223 (154.7 ± 36.4) 172 - 780 (382.7 ± 138.1) 95 - 710 (391.1 ± 172.1) 1-29 (12.5 ± 7.6) 1-3 (2.4 ± 0.6) Table 1. Patient Demographics and results pertaining to follow up, operative time and amount of fat grafted to either breast.