TERRI-ANN NATALIE KELLY
EDUCATION
Columbia University, New York, New York.
Doctor of Philosophy in Biomedical Engineering (Tissue Engineering), May 2006.
Dissertation Title: Functional Tissue Engineering of Articular Cartilage: Characterization and
Optimization of Chondrocyte-Seeded Agarose Hydrogels (Advisor: Dr. Clark Hung).
Master of Philosophy in Biomedical Engineering, February 2006.
Master of Science in Biomedical Engineering, February 2001.
Worcester Polytechnic Institute, Worcester, Massachusetts.
Bachelor of Science in Biology, May 1998.
RESEARCH EXPERIENCE
Postdoctoral Research Scientist, Dr. Clark Hung, mentor. Department of Biomedical Engineering,
Columbia University. June 2006 to December 2006; November 2011 to Present.
Postdoctoral Fellow, Dr. Jeffrey Urbach [GU] and Dr. Herbert Geller [NIH], mentors. Department of
Physics, Georgetown University and National Heart, Lung and Blood Institute, NIH. December 2006 to
August 2009.
Graduate Research Assistant, Dr. Clark Hung, mentor. Department of Biomedical Engineering,
Columbia University. October 1999 to May 2006.
Research Assistant/Research Laboratory Technician, Dr. Jean King, mentor. Department of
Psychiatry’s Behavioral Neuroscience Program, University of Massachusetts Medical Center. October
1996 to July 1999.
Research Assistant, Dr. Jean King and Dr. John Fray, mentors. Department of Psychiatry’s Behavioral
Neuroscience Program and Department of Physiology, University of Massachusetts Medical Center.
June 1994 to December 1994; June 1995 to August 1995.
Consultant, Dr. Peter Christopher, mentor. Worcester Polytechnic Institute, Worcester, MA and Institute
of Costa Rican Tourism, San Jose, Costa Rica. January 1997 to July 1997.
ACADEMIC SERVICES AND COMMUNITY OUTREACH
Volunteer via Columbia University Club of DC, Food and Friends, Washington, DC (2008-2009).
Panelist, “Voices from the Field: Real Life Experiences,“ National GEM Consortium GRAD Lab,
Columbia University, April 5, 2008.
TEACHING/LECTURING EXPERIENCE
Teaching Assistant, Department of Biomedical Engineering, Columbia University.
Fall 2000
Tissue Engineering I.
Fall 2000
Undergraduate Lab I: Cell Counting and Encapsulation Module.
Spring 2000 Principles of Biomedical Engineering II.
Fall 1999
Principles of Biomedical Engineering I.
Guest Lecturer, Summer High School Program, Columbia University, Summer 2006.
Guest Lecturer, Interdisciplinary Program in Neuroscience, Georgetown University, Fall 2007.
Guest Lecturer, Bioprocessing, Department of Chemical Engineering, Howard University, Spring 2009.
FUNDING, LEADERSHIP, AND AWARDS
NIH (R21 EB014382) Postdoctoral Research Funding (2011-2013).
Fellows Advisory Committee, National Heart, Lung, and Blood Institute, NIH (2008-2009).
One of 75 attendees selected from over 1000 applicants to attend the NSF ADVANCED Workshop on
Negotiating the Ideal Faculty Position, Rice University, Houston, TX (2008).
NIH (R01 AR49922) Graduate Research Funding (2000-2005).
NIH (R01 AR46568) Graduate Research Funding (2000-2003).
Graduate Biomedical Engineering Group, Columbia University - Treasurer (2001-2002).
Engineering Graduate Student Council, Columbia University - Biomedical Engineering Departmental
Representative (2000).
Columbia University Teaching Assistantship (1999-2000).
PUBLICATIONS
1. King JA, Kelly T-AN, Delville Y. Adult levels of testosterone alter catecholamine innervation in an
animal model of attention-deficit hyperactivity disorder. Neuropsychobiology 42(4):163-168, 2000.
2. King JA, Rosal MC, Ma Y, Reed G, Kelly T-AN, Stanek EJ, Ockene IS. Sequence and seasonal
effects of salivary cortisol. Behavioral Medicine 26(2):67-73, 2000.
3. Kelly T-AN, Wang CC-B, Mauck RL, Ateshian GA, Hung CT. Effects of seeding density and
native pericellular matrix on the response of chondrocytes seeded in agarose hydrogels to
dynamic deformational loading. Biorheology 41(3-4):223-237, 2004.
4. Basalo IM, Mauck RL, Kelly T-AN, Nicoll SB, Chen FH, Hung CT, Ateshian GA. Cartilage
interstitial fluid load support in unconfined compression following enzymatic digestion. Journal of
Biomechanical Engineering 126(6):779-786, 2004.
5. Ng KW, Wang CC-B, Mauck RL, Kelly T-AN, Chahine NO, Costa KD, Ateshian GA, Hung CT. A
layered agarose approach to fabricate depth-dependent inhomogeneity in chondrocyte-seeded
constructs. Journal of Orthopaedic Research 23(1):134-141, 2005.
6. Kelly T-AN, Ng KW, Wang CC-B, Ateshian GA, Hung CT. Spatial and temporal development of
chondrocyte-seeded agarose constructs in free-swelling and dynamically loaded cultures. Journal
of Biomechanics 39(8):1489-1497, 2006.
7. Ho MM, Kelly T-AN, Guo XE, Ateshian GA, Hung CT. Spatially varying material properties of rat
caudal intervertebral disc. Spine 31(15): E486-E493, 2006.
8. Kelly T-AN, Fisher MB, Oswald ES, Tai T, Mauck RL, Ateshian GA, Hung CT. Low-serum media
and dynamic loading in tissue engineering of articular cartilage. Annals of Biomedical Engineering
36(5):769-779, 2008; Epub Feb 26, 2008.
9. Ng KW, Defrancis JG, Kelly T-AN, Ho MM, O’Conor CJ, Ateshian GA, Hung CT. Amino acids
supply in culture media is not a limiting factor in the matrix synthesis of engineered cartilage
tissue. Amino Acid 35(2):433-438, 2008.
10. Kelly T-AN, Ng KW, Ateshian GA, Hung CT. Analysis of radial material properties and matrix
composition of chondrocyte-seeded agarose constructs. Osteoarthritis and Cartilage 17(1):73-82,
2009; Epub Sept 18, 2008.
11. Ng KW, Mauck RL, Wang CC-B, Kelly T-AN, Ho MM-Y, Chen FH, Ateshian GA, Hung CT. Duty
Cycle of Deformational Loading Influences the Growth of Engineered Articular Cartilage. Journal
of Cellular and Molecular Bioengineering 2(3):386-394, 2009.
12. Kelly T-AN, Katagiri Y, Vartanian KB, Kumar P, Chen II, Rosoff WJ, Urbach JS, Geller HM.
Localized alteration of microtubule polymerization in response to guidance cues. Journal of
Neuroscience Research 88(14):3024-3033, 2010.
MANUSCRIPT IN PREPARATION
1. Kelly T-AN, Lima EG, Ateshian GA, Hung CT. Dynamic deformational loading and media
formulation enhance tension-compression nonlinearity in tissue-engineered articular cartilage.
Manuscript in preparation.
PRESENTATION/ABSTRACTS
1. Kelly T-AN, King JA, Adolphe S, Delville Y. Colocalization of catecholamine and androgen
receptors in forebrain in an animal model of ADHD. Transactions of the Society for Neuroscience
23: 1364, 1997.
2. Kelly T-AN, King JA, Delville Y, Fray JCS. Developmental alteration in the monoaminergic
system in an animal model of ADHD. Transactions of the Society for Neuroscience 25: 491,
1999.
3. Mauck RL, Seyhan SL, Kelly T-AN, Hung CT, Ateshian GA. Seeding density influences the
development of mechanical properties of agarose construct. Transactions of the Orthopaedic
Research Society 26: 432, 2001.
4. Wang CC-B, Chahine NO, Kelly T-AN, Valhmu WB, Hung CT, Ateshian GA. Optical
determination of anisotropic material properties of bovine articular cartilage in compression.
Advances in Bioengineering ASME, BED 50, 719-720, 2001.
5. Kelly T-AN, Wang CC-B, Chahine NO, Ateshian GA, Hung CT. Temporal development of
material properties in free swelling chondrocyte-seeded agarose constructs. Advances in
Bioengineering ASME IMECE2001/BED 23144, 2001.
6. Chahine NO, Wang CC-B, Kelly T-AN, Lai WM, Hung CT, Ateshian GA. The strain-softening of
bovine articular cartilage under infinitesimal deformation in unconfined compression. Annals of
Biomedical Engineering 29S1, S-31, 2001.
7. Wang CC-B, Chahine NO, Kelly T-AN, Lai WM, Hung CT, Ateshian GA. The strain-softening of
bovine articular cartilage under infinitesimal deformation in unconfined compression. Advances in
Bioengineering ASME, IMECE2001/BED 23061, 2001.
8. Laroux MA, Kelly T-AN, Palmer GD, Seyhan SL, Hung CT. Osmotic regulation of chondrocyte
gene expression occurs independent of changes in cell morphology and size. Transactions of the
Orthopaedic Research Society 27: 384, 2002.
9. Wang CC-B, Chahine NO, Kelly T-AN, Hung CT, Ateshian GA. Application of a tensioncompression nonlinearity model to anisotropic material properties of articular cartilage.
Transactions of the Orthopaedic Research Society 27, 394, 2002.
10. Kelly T-AN, Wang CC,-B Mauck RL, Chahine NO, Ateshian GA, Hung CT. Effects of dynamic
loading on material properties of chondron-seeded hydrogels. Transaction of the Orthopaedic
Research Society 28: 132, 2003.
11. Chahine NO, Wang CC-B, Kelly T-AN, Elbeshbeshy RR, Mauck RL, Hung CT, Ateshian GA. The
effect of finite compressive strain on chondrocyte viability in statically loaded bovine articular
cartilage. Transactions of the Orthopaedic Research Society 28: 646, 2003.
12. Kelly T-AN, Wang CC-B, Mauck RL, Ateshian GA, Hung CT. Effects of seeding density and
native pericellular matrix on the response of chondrocytes to dynamic loading. Transactions of
the ASME-BED: 187-188, 2003.
13. Wang CC-B, Kelly T-AN, Mauck RL, Ateshian GA, Hung CT. Temporal and spatial development
of construct stiffness in chondrocyte-seeded agarose disks cultured in free-swelling and
dynamically loaded configurations. Transaction of the ASME-BED: 279-280, 2003.
14. Kelly T-AN, Ho MM, Mauck RL, Ateshian GA, Hung CT. Effects of pre-elaborated ECM on
development of functional properties in chondrocyte-seeded agarose constructs subjected to
physiologic deformational loading. Transactions of the Orthopaedic Research Society 29: 695,
2004.
15. Kelly T-AN, Oswald ES, Mauck RL, Ateshian GA, Hung CT. Reduced serum dependence: tissue
engineering of cartilage in ITS supplemented media. Transactions of the Orthopaedic Research
Society 29: 725, 2004.
16. Hung CT, Kelly T-AN, Lima EG, Ng KW, Ateshian GA. A functional tissue engineering strategy
for repair and replacement of osteoarthritic cartilage. Transaction of the European Society of
Biomechanics, July 4-7, s'-Hertogenbosch, The Netherlands, 2004.
17. Ng KW, Wang CC-B, Kelly T-AN, Chahine NO, Costa KD, Ateshian GA, Hung CT. Development
of depth-dependent inhomogeneity in bilayered chondrocyte-seeded agarose constructs.
Biomedical Engineering Society Annual Meeting, October 13-16, Philadelphia, PA, 2004.
18. Hung CT, Lima EG, Ng KW, Kelly T-AN, Chahine NO, Mauck RL, Ateshian GA, Costa KD.
Applied deformational loading to promote/guide development of chondrocyte-seeded agarose
constructs. Biomedical Engineering Society Annual Meeting, October 13-16, Philadelphia, PA,
2004.
19. Kelly T-AN, Ng KW, Lee EJ, Lima EG, Statman LY, Doty SB, Costa KD, Ateshian GA, Hung CT.
Development of radial properties of engineered articular cartilage using unconfined compression
loading. Transactions of the Orthopaedic Research Society 30: 1790, 2005.
20. Kelly T-AN, Fisher MB, Lima EG, Ateshian GA, Hung CT. Integrative properties of chondrocyteseeded agarose constructs. Transactions of the Orthopaedic Research Society 30: 1788, 2005.
21. Ng KW, Saliman JD, Kelly T-AN, Statman LY, Ateshian GA, Hung, CT. Hyaluronan modulates
the material properties and biochemical content of dynamically-loaded chondrocyte-seeded
agarose constructs. Transactions of the Orthopaedic Research Society 30: 1787, 2005.
22. Ng KW, Saliman JD, Kelly T-AN, Statman LY, Ateshian GA, Hung, CT. Collagen hydrolysate
increases the mechanical properties and type II collagen synthesis of tissue engineered articular
cartilage. Transactions of the Orthopaedic Research Society 30: 259, 2005.
23. Ho MM, Ng, KW, Kelly T-AN, Ateshian GA, Kuroki K, Cook JL, Hung, CT. Synoviocyte potential
for articular cartilage tissue engineering and repair. Transactions of the Orthopaedic Research
Society 30: 1789, 2005.
24. Kelly T-AN, Wang CC-B, Ng KW, Lima EG, Statman LY, Ateshian GA, Hung CT. Development of
construct stiffness and Poisson’s ratio in chondrocyte-seeded agarose hydrogels cultured in freeswelling and dynamic loading configuration. New England Science Symposium, March 4, Boston,
MA, 2005.
25. Kelly T-AN, Chahine NO, Fisher MB, Ng KW, Tai T, Ateshian GA, Hung CT. Tensioncompression nonlinearity in chondrocyte-seeded agarose hydrogels. Summer Bioengineering
Conference, June 22-26, Vail, CO, 2005.
26. Ho MM, Kelly T-AN, Ateshian GA, Hung CT. Rat tail intervertebral disc mechanical response with
intact and excised nucleus pulposus. Summer Bioengineering Conference, June 22-26, Vail, CO,
2005.
27. Hung CT, Kelly T-AN, Chahine NO, Ateshian GA. Cartilage Tissue Engineering: Implications of
Applied Deformational Loading and Solute Transport. Biomedical Engineering Society Annual
Meeting, September 28-October 1, Baltimore, MD, 2005.
28. Kelly T-AN, Ng KW, Tai T, Ateshian GA, Hung CT. Effects of low-serum media and dynamic
loading on chondrocyte-seeded constructs. Transactions of the Orthopaedic Research Society
31: 790, 2006.
29. Ng KW, Bian LM, Lin EY, Kelly T-AN, Ateshian GA, Hung CT. Essential amino acids
supplementation modulates chondrocyte behavior in 3D agarose culture. Transactions of the
Orthopaedic Research Society 31: 791, 2006.
30. Ng KW, Friedman DJ, Statman LY, Kelly T-AN, Ateshian GA, Hung CT. Cell seeding method
influences tissue spatial development in chondrocyte-seeded gelatin scaffolds. Transactions of
the Orthopaedic Research Society 31: 793, 2006.
31. Ng KW, Kugler L, Kelly T-AN, DeFrancis J, Ateshian GA, Hung CT. Enzymatic Removal of
Agarose Scaffold for Tissue Engineered Cartilage. Summer Bioengineering Conference, June 2125, 2006.
32. Hung CT, Kelly T-AN, Lima EG, Ng KW, Bian LM, Ateshian GA. Characterization of chondrocyteseeded agarose constructs subjected to applied deformational loading. Biomedical Engineering
Society Annual Meeting, October 11-14, Chicago, IL, 2006.
33. Kelly T-AN, Ateshian GA, Hung CT. Radial development of material properties in chondrocyteseeded agarose hydrogels. Transactions of the Orthopaedic Research Society 32: 1478, 2007.
34. Kelly T-AN, Ateshian GA, Hung CT. Effect of dynamic loading on tension-compression
nonlinearity in engineered cartilage. Transactions of the Orthopaedic Research Society 32: 1481,
2007.
35. Kelly T-AN, Thach T, Vartanian K, Katagiri H, Geller HM. Microtubule polymerization rates
correlates with process outgrowth in PC12 cells. Program No. 238.23. 2007 Neuroscience
Meeting Planner. San Diego, CA: Society for Neuroscience, 2007.
36. Kelly T-AN, Chen I, Thach T, Katagiri H, Urbach JS, Geller HM. Microtubule polymerization rates
correlates with treatments that affect neurite outgrowth in PC12 cells. The American Society for
Cell Biology Annual Meeting, December 1-5, Washington, DC, 2007.
37. Bian LM, Kelly T-AN, Lima EG, Ateshian GA, Hung CT. Finite element modeling of osmotic
swelling in tissue-engineered cartilage. Summer Bioengineering Conference, June 25-29, Marco
Island, FL, 2008.
38. Kelly T-AN, Chen I, Urbach JS, Geller HM. Chondroitin sulfate proteoglycan boundaries induce
growth cone turning via localized mechanisms. National Heart, Lung, and Blood Institute Fellow’s
Retreat, March 13-14, Annapolis, MD, 2008.
39. Kelly T-AN, Rosoff WJ, Urbach JS, Geller HM. Interaction between myosin II and microtubule
polymerization in neuronal PC12 cells. Society for Neuroscience Annual Meeting, November 1519, Washington, DC, 2008.
40. Rosoff WJ, Capuani EMI, Kelly T-AN, Geller HM, Urbach HM. Examination of growth cone
interactions with three dimensional collagen matrices. Society for Neuroscience Annual Meeting,
November 15-19, Washington, DC, 2008.