Application for Consortium Pilot Awards

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FUNDS AVAILABLE FOR PILOT GRANTS

FROM THE CANCER CENTER SUPPORT GRANT

OPEN TO ALL CONSORTIUM MEMBERS

August 2015

Release Date: August 5, 2015

Due Date: October 2, 2015

Funds are available from the Fred Hutchinson/University of Washington Cancer Consortium (Consortium) Cancer Center

Support Grant (CCSG) to support cancer-related pilot projects. This competition will provide awards of up $80,000 direct for one year to support pilot projects. Consortium members are eligible for this pilot funding (see section B below for more details).

There are no limitations on research topic, as long as the problem under study is cancer focused. Highly innovative concepts that have the potential to improve the lives of cancer patients are encouraged. Also included in this competition are two pilots targeted at areas of special interest to the Consortium – Global Health and Health

Disparities research – see below for more details.

The guidelines for this announcement are as follows:

1. The pilot proposals should represent a new project or new research direction for the principal investigator that will provide preliminary data needed to seek outside funding. Applications should not be an extension of ongoing wellestablished or recently funded studies. Grants from more established investigators (e.g., Full Members or Professors) will be competitive if they are for a pilot study that is needed to establish a new direction or research project and collaborations between established investigators and junior colleagues will be viewed favorably. We are particularly interested in projects that forge new collaborations between investigators in different disciplines, although this will be considered in balance with scientific merit when evaluating proposals.

2. In your proposal, please show how this work is a pilot project. The application should:

Describe how this work is a new direction for your laboratory and is highly innovative, yet technically feasible.

Show how this work reveals the homegrown intellectual and creative strengths of the investigators.

Interdisciplinary work and new collaborations are encouraged.

Describe how this work will benefit cancer prevention, diagnosis or treatment.

Grants with no preliminary data are encouraged. Please describe what 2-3 pieces of data can be gathered that will position this work for NIH funding.

Indicate how this grant is a timely opportunity that might otherwise be lost if delayed by the NIH review cycle

3. Targeted Pilots: Included in this competition are two pilot grants targeted at special topics – Global Health and Health

Disparities Research. These pilots should follow all guidelines in this RFA. Please state in the abstract if the pilot should be considered a Global Health or Health Disparities Research pilot award. Any project with foreign components as defined in the NIH Grants Policy Statement are required to obtain State Department clearance prior to using CCSG funds for this work.

Inquires about how specific projects fit these guidelines may be directed to Dr. Marion Dorer, Consortium

Administrator ( mdorer@fhcrc.org

, 667-3001).

4. The awards will total up to a maximum of $80,000 in direct costs for a single year; facilities and administrative (F&A) costs will be included in addition to this amount at the institutional F&A cost rate. A budget in PHS 398 format should be included in the pilot award application indicating the amount requested and a general breakdown of how the funds will be spent. A brief budget justification is required.

5. Plan to spend your money in 1 year. A single no-cost extension will be considered; all no-cost extensions will be reviewed by the pilot review committee and extension beyond year 2 will be subject to approval by the review committee and Consortium leadership.

CCSG Pilot Funds —Instructions

APPLICATION PROCESS

A. Application Format:

Applicants must submit the attached 2015 Pilot Application. The application should clearly outline the aims and the strategy of the project and why funding through this pilot grant mechanism is appropriate, including how you anticipate this support will generate future funding.

1. On the cover page, include requested project information and an abstract that states the primary hypothesis. The abstract and the proposal should both be written to be understandable by reviewers with diverse expertise, as the review panel will consist of faculty from across the Consortium.

2. The length of the proposal is 2 pages maximum (budget, figures/tables, and references can each take an additional page).

3. If you have received CCSG pilot funding in the past 5 years, include a summary (1 page maximum) describing the main aim of the funded project, and whether any publications, new collaborations, or outside grants resulted from the funding.

4. Include an NIH Biosketch listing your current sources of funding and a one-line description of the primary goal of each funded grant. A biosketch should be included for each key personnel involved with the project. FAQs on the current NIH Biosketch format, samples, and templates: http://grants.nih.gov/grants/policy/faq_biosketches.htm

B. Eligibility:

Anyone who is a member of the Cancer Consortium on or by the October 2 due date (noted in section C below) may apply for funds, and only these individuals can serve as principal investigator of the pilot grant. Non-Consortium members and Affiliate members* can be involved in the pilot project as a collaborator, but a Consortium member must be the principal investigator. Please see the Consortium member list posted at http://www.cancerconsortium.org/membership for an up-to-date listing of members.

*Affiliate members are not considered full Consortium members and are not eligible to apply for CCSG pilot awards as principal investigators.

C. Criteria for funding :

Applications should meet the criteria stated above for pilot awards (#3 in guidelines).

Successful applications will:

 advance cancer-related research.

 yield pivotal data in a one year time frame

 use cutting edge approaches

 represent unique intellectual perspectives coupled with cutting edge approaches

D. Application Due Date:

Applications are due Friday, October 2, 2015 by 5:00 pm. Applications received after this deadline will not be accepted for evaluation by the Consortium Pilot Award Review Committee.

E. Application Submission:

Applications should be submitted via email as one complete pdf file to cancerconsortium@fhcrc.org

.

F. Award Timeline:

Applications will be reviewed in October and funding is expected to begin by November 15, 2015.

CCSG Pilot Funds —Instructions

G. University of Washington/ Seattle Children’s-- Special Instructions:

Projects involving a principal investigator based at the University of Washington , Seattle Children’s, or any institution other than FHCRC must submit a Letter of Intent from their Sponsored Projects/ Sponsored Research office along with their pilot application.

UW Investigators may contact Denise Barnes (206) 685-8710 or barmen@uw.edu

with questions about the eGC1 process.

Questions:

Please reference the accompanying FAQ document (p.11), which addresses the most common questions regarding

CCSG Pilot Awards. If you have additional questions contact Jennifer Jacyszyn, CCSG Award Administrator, at 206-667-

6250 or jblaesin@fhcrc.org

.

CCSG Pilot Funds —Instructions

Application for 2015 CCSG Pilot Awards

Project Title :

Key Personnel

(Please include an NIH Biosketch for each individual)

Name Professional Title

Role on

Project Institution

PI

Consortium

Member? 1/

(Y/N)

1/ Consortium member listing can be found at: http://www.cancerconsortium.org/membership

Is this a targeted proposal? (Y/N) If yes: Global Health ______ Health Disparities _____

Does this study involve foreign components? (Y/N)

Does this study involve human subjects? (Y/N) Animals? (Y/N)

IRB/ IACUC Number: ___________

(IRB and/or IACUC approval must be obtained if this grant is awarded and before any funds will be activated.)

Have you received CCSG pilot funding in the past 5 years?

(Y/N)

(If yes, please complete page 8 of this application)

ABSTRACT

(200 words or less)

CCSG Pilot Funds Application- 2015

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Research Plan (2 page maximum)

CCSG Pilot Funds Application- 2015

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Research Plan (page 2)

______________________________________________________________________________

CCSG Pilot Funds Application- 2015

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DETAILED BUDGET FOR INITIAL BUDGET PERIOD

DIRECT COSTS ONLY

List PERSONNEL (Applicant organization only)

Use Cal, Acad, or Summer to Enter Months Devoted to Project

Enter Dollar Amounts Requested (omit cents) for Salary Requested and Fringe Benefits

NAME

ROLE ON

PROJECT

PD/PI

Cal.

Mnths

FROM

Acad.

Mnths

Summer

Mnths

INST.BASE

SALARY

SALARY

REQUESTED

THROUGH

FRINGE

BENEFITS TOTAL

CONSULTANT COSTS

EQUIPMENT (Itemize)

SUBTOTALS

SUPPLIES (Itemize by category)

TRAVEL

INPATIENT CARE COSTS

OUTPATIENT CARE COSTS

ALTERATIONS AND RENOVATIONS (Itemize by category)

OTHER EXPENSES (Itemize by category)

CONSORTIUM/CONTRACTUAL COSTS DIRECT COSTS

SUBTOTAL DIRECT COSTS FOR INITIAL BUDGET PERIOD (Item 7a, Face Page)

CONSORTIUM/CONTRACTUAL COSTS FACILITIES AND ADMINISTRATIVE COSTS

$

CCSG Pilot Funds Application- 2015

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TOTAL DIRECT COSTS FOR INITIAL BUDGET PERIOD

$

CCSG Pilot Funds Application- 2015

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Budget Justification ( 1 page)

CCSG Pilot Funds Application- 2015

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Figures and Tables (one page maximum)

CCSG Pilot Funds Application- 2015

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References (one page maximum)

CCSG Pilot Funds Application- 2015

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Summary of Previous Results from CCSG-funded Pilot Project

(complete if applicable; one page maximum)

CCSG Pilot Funds Application- 2015

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Biosketches for Key Personnel

Include biosketches for all key personnel involved with the pilot project, using the current NIH biosketch format.

CCSG Pilot Funds Application- 2015

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CCSG Pilot FAQs

Q. How can I check to see if I am a Consortium member and what program I belong to?

A. You can find this information on the Consortium website at: http://is-ext.fhcrc.org/sites/consortium/ccdb/members.php

*Note that Affiliate members are not eligible to apply for CCSG Developmental Funds as the principal investigator.

Q. How long do I have to spend these funds if I receive an award?

A. Awards are intended to support projects of one year in duration.

Q. Are there unallowable costs on these projects?

A. Pilot funds may not be used to pay for tuition, upgrades to established shared resources, or equipment

Q. Does the NIH Salary Cap apply to these awards?

A. Yes. The CCSG is a federal award and investigators are limited to the current Executive Level II cap of $183,300. Information regarding the prime award can be found here: http://www.cancerconsortium.org/en/about/ccsg-information.html

Q. Does the Principal Investigator need to charge salary and effort to these projects?

A. The PI must have some measurable effort on the project for direction and supervision. It is not required that the PI charge salary on the project.

Q. How many awards will be made?

A. It is anticipated that five or six awards will be made for up to $80,000 in direct costs, plus F&A.

FHCRC Principal Investigators

Q. Do projects submitted by Fred Hutch-based PI need an Attachment A?

A. No. Projects with a Fred Hutch-based PI will only need to do an Attachment A if funded.

Q. Can my project have UW or Children’s collaborators who receive funds from the pilot award?

A. Yes. You will need to issue a subaward off of your project to UW/ Children’s for funds that will be spent there. Additional F&A will be included in your award and will not come out of your direct costs.

UW, Children’s, or other institution Principal Investigators

Q: Do projects with a UW or Children’s- based PI need to submit an e-GC1?

A: Yes. Institutional sign-off should be received prior to submission of a pilot award proposal for review, and a Letter of Intent from the corresponding institution must accompany the pilot application. Contact your institution’s Office of Sponsored Project/ Office of Sponsored Research for guidance.

Q: If there are FHCRC personnel that will be paid from this award, or other FHCRC direct costs, how will this be managed?

A: If the project is funded, a subaward will be issued for costs to be incurred at the investigator’s primary institution. Funds to be spent at FHCRC will be deducted from the award amount prior to issuing the subaward and the balance will be issued to UW or Children’s.

For additional questions, contact Jennifer Jacyszyn at 206-667-6250 or jblaesin@fhcrc.org.

CCSG Pilot Funds Application- 2015

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