D-limonene/Limonene
Limonene
Studies have shown that limonene have anti- cancer effects. Limonene increase the levels of
liver enzymes involved in detoxifying carcinogens. The Glutathione S-transferase (GST) is
a system which eliminates carcinogens. Limonene seems to promote the GST system in
the liver and small bowel, thereby decreasing the damaging effects of carcinogens.
Animal studies demonstrated that dietary limonene reduced mammary tumor
growth.
Orange essential oil for your body:
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Aids digestion and detoxifies your system
Eases constipation
Relieves water retention
Stimulates your adrenals
Promotes circulation
Combats cellulite
Increases your absorption of vitamin C
Supports your immunity to fight colds and flu
Strengthens and rejuvenates your skin
Orange essential oil for your mind:
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Reduces stress, nervousness and tension
Energizes and fights lethargy and fatigue
Treats depression during menopause
Induces sleep when combined with lavender
Promotes creative thinking
Moves energy out of your head and into your heart
Encourages right brain functioning
Orange essential oil for your home:
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Cleans and disinfects
Removes stains, especially from counter tops
Is an effective degreaser
Limonene and Orange Oil: Potent Anti-Cancer
Ingredient
Besides being such an effective mind and body healer, new research has shown
that limonene, a component that makes up greater than 90% of pure orange oil,
has amazing anti-cancer properties. The limonene (also known as dlimonene) in orange essential oil can be effective in fighting
melanoma, liver, breast, lung, and pancreatic cancers.1 For skin cancers,
people use limonene topically; it can also be taken internally as an effective
natural cancer treatment and preventative.
D-limonene/Limonene
-limonene is a monterpene, a compound from plants found to cure tumors and
cancers. The best source of d-limonene is the oil from orange peels. Researchers
at the University of Wisconsin found that when d-limonene was added to the diets
of rats that had developed tumors, 90% of tumors disappear completely. One way to
have a d-limonene intake is to juice the orange and the peel together - just make sure the
oranges are organically grown. Monoterpenes possess many characteristics of ideal
chemopreventive agents, namely, efficacious anti-tumor activity, commercial availability,
low cost, oral bioavailability, and low toxicity, which made it feasible to begin considering them
for human cancer chemoprevention testing. Most essential oils include monoterpenes-compounds that contain 10 carbon molecules often arranged in a ring. Monoterpenes are formed
in the mevalonic acid pathway in plants, the same pathway that makes cholesterol in animals and
humans. D-limonene, which comprises more than 90% of orange peel oil, has
chemopreventive activity against rodent mammary, skin, liver, lung, and fore
stomach cancers. D-limonene also has chemotherapeutic activity against rodent
pancreatic tumors. Because d-limonene and perillyl affect the pathway that produces
cholesterol, they can inhibit cholesterol synthesis, thereby eliminating a minor contributor to
cancer formation. Monoterpenes also increase the levels of liver enzymes involved in
detoxifying carcinogens, an effect that decreases the possibility carcinogens will
cause cellular damage. In addition, monoterpenes stimulate apoptosis, a cellular selfdestruction mechanism triggered when a cell’s DNA is badly damaged. This safety
feature is generally activated before a cell becomes cancerous. Finally, monoterpenes inhibit
protein isoprenylation. The cell uses this process to help a particular protein involved in cell
growth find its proper location within the cell. If the protein is not in the right place, it becomes
overactive and can spur cancerous cell growth. Thus, monoterpenes would appear to act through
multiple mechanisms in the chemoprevention and chemotherapy of cancer. A number of dietary
monoterpenes have anti-tumor activity, exhibiting not only the ability to prevent the
formation or progression of cancer, but to reverse existing malignant tumors.
Dlimonene has well-established chemopreventive activity against many cancer types.
Dlimonene has been shown to inhibit the development of spontaneous neoplasms in
mice receiving 1200 mg/kg orally (NTP 1990).
Also see Monoterpenes.
NATURALCANCERTREATMENTS
Source
Check sources and best prices at Froogle. Just click
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Select "100 Results". Select "Sort by Price: Low to High". Further Reading
• Surviving Cancer by Margie Levine. Excerpt from page 145 "... And because citrus skin is also
thought to contain the cancer-fighting substance D-limonene, I let it do double duty in tea (which
I ..." • The Cancer Survival Cookbook : 200 Quick & Easy Recipes with Helpful Eating Hints by
Donna L. Weihofen. Excerpt from page 36 "... DNA from oxidative damage. Vitamin C may
further help prevent cancer by preventing the formation of nitrosamines. Citrus fruits also
contain coumarins and limonene, which have been shown to increase the activity of other ..."
• What to Eat Now: The Cancer Lifeline Cookbook : And Easy-To-Use Nutrition Guide to
Delicious and Healthy Eating for Cancer Patients, Survivors, and Caregivers by Rachel Keim,
Ginny Smith. Excerpt from page 13 "... Citrus Fruit Possible Benefits Citrus fruit is packed with
the cancer-inhibiting substances vitamin C, flavonoids, limonenes, and terpenes. Cells in the
immune system, including T cells ..." • Healing Essence: A Cancer Doctor’s Practical Program for
Hope and Recovery by Mitchell L. Gaynor. Excerpt from page 220 "... able to enhance the body’s
own ability to ward off cancer. Examples of other phytochemicals are ... from multiplying). Citrus
fruits contain limonene, which increases detoxifying enzymes..."
References • Elson CE, Yu SG. The chemoprevention of cancer by mevalonate-derived
constituents of fruits and vegetables. J Nutr 1994;124:607-14. • Gould MN. Cancer
chemoprevention and therapy by monoterpenes. Environ Health Perspect 1997;105:S977-9. •
Mills JJ, et al. Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol. Cancer
Res 1995; 55:979-83. • Hohl RJ. Monoterpenes as regulators of malignant cell proliferation. In:
American Institute for Cancer Research. Dietary Phytochemicals in Cancer Prevention and
Treatment. New York: Plenum Press;1996. •
http://www.naturdoctor.com/Chapters/Research/PancreaticCancer.pdf