REQUEST FOR PROPOSALS:
APPROACHES AND METHODS IN COMPUTATIONAL GENOMICS,
COMPUTATIONAL PROTEOMICS, AND ASSOCIATED RESEARCH
Overview
Compute the Cure is an NVIDIA Foundation initiative that aims to support cancer researchers in their
search for a cure.
We are seeking proposals for projects that leverage computational genomics or proteomics to have a
dramatic impact on the battle against cancer and that reduce the time it takes for research outcomes
to be effective in a clinical environment.
We will award up to $200,000 to the selected project.
Areas of interest include:

New fields of study, new techniques, new projects. “Fertile ground” where there is the
potential for impact, but the researcher has just started securing funds or is in the early phase
of being funded.

Projects in which computational methods or structures (data processing algorithms, pipelines,
simulations, etc.) are deployed within a research or clinical environment (or both), with the
goal of significantly reducing the time it takes for research results to increase the rate of
successful treatment outcomes in a clinical environment.

Computational methods or structures (data processing algorithms, pipelines, simulations, etc.)
being constructed or improved that increase the speed and/or accuracy with which genomes
are sequenced, analyzed and prepared for analysis, discovery and/or treatment.

Other areas in the cancer research spectrum where computation is being utilized to improve
the availability of genomic information that leads to a better understanding of cancer.

Both CPU- and/or GPU-accelerated approaches to computational genomics or computational
proteomics. Funding may be used for salaries and hardware/software.
NVIDIA Foundation, Compute the Cure, Computational Genomics and Proteomics, August 2013
Review Criteria
Proposals will be evaluated according to the following criteria:

Innovation: Proposed project supports new approaches or applies new insights in
computational genomics or computational proteomics.

Leverage: Results of the project can be used by or benefit multiple researchers and motivate
new innovations.

Focus and Impact: Project focuses on solving a specific problem in computational genomics or
computational proteomics, and will have a substantial impact in the battle against cancer.

Measurable: Project has clear goals and milestones that can be achieved within a reasonable
timeframe.
Process and Timeline
October 7, 2013:
Applications due
October 8 – October 31, 2013:
Review applications, interviews with finalists
November 1, 2013:
Announce recipient
NVIDIA Foundation, Compute the Cure, Computational Genomics and Proteomics, August 2013
Compute the Cure Project Proposal
Please complete this form and return it by 5:00pm PDT on October 7, 2013.
Questions and/or completed applications should be emailed to Liz Austin, NVIDIA Foundation,
eaustin@nvidia.com. Applications should be sent as a Microsoft® Word or Adobe® PDF file.
Contact Information:
Organization Name
Contact Name
Contact Title/Position
Contact Email and Phone
Organization Address
How did you hear about this opportunity?
Email
Colleague/Friend (please include name and
organization)______________________________________
Website (please specify)____________________
Other (please specify)______________________
Project Snapshot:
Project Name
Short Description of Project (2-3 sentences)
What is the total budget for this project, in USD?
How specifically would the NVIDIA Foundation
funding be used?
Please break budget down by:
Salaries
Equipment
Other (please specify)
Total
Principal Investigator/Project Lead Name and Title
NVIDIA Foundation, Compute the Cure, Computational Genomics and Proteomics, August 2013
Project Abstract:
Please write a high-level project abstract using layperson language. The abstract should focus on the
problem and how the project/project results will have an impact in the battle against cancer, in nonscientific terminology. (max. 300 words)
Project Details:
1.
Describe, in detail, the problem to be solved by your proposed project. (max. 300 words)
2. How will your proposed project address this problem? What is the expected impact on the field
of cancer research? (max. 500 words)
3. Specifically, how would you apply computational methods to the problem addressed by your
proposed project? (max. 500 words)
4. How is your proposed solution different than other existing approaches to this problem? (max.
300 words)
5. How are you currently using computation in the field(s) of genomics and/or proteomics? Are you
currently using GPUs in your research? If so, please describe. (max. 500 words)
6. Provide a high-level timeline, including major milestones, for the proposed project. (max. 100
words)
7. Describe the specific qualifications and experience of the principal investigator and project
team that will enable the successful completion of this project. On what prior projects have
members of this team worked together? You may cut and paste bios that you’ve used for
previous proposals. (max. 300 words)
NVIDIA Foundation, Compute the Cure, Computational Genomics and Proteomics, August 2013