Focus Plan Texarkana Independent School District GRADING PERIOD: WRITER: Biology – 2nd six weeks Chemistry – 3rd six weeks L. Petty PLAN CODE: COURSE/SUBJECT: 10th grade science GRADE(S): 10th TIME ALLOTTED FOR INSTRUCTION: 1½ hours TITLE: The Pattern LESSON TOPIC: DNA components TAKS OBJECTIVE: Objective 2 The student will demonstrate an understanding of the organization of living systems. 10.6 The student knows the structures and functions of nucleic acids in the mechanisms of genetics. The student is expected to: (A) describe components of deoxyribonucleic acid (DNA), and illustrate how information for specifying the traits of an organism is carried in the DNA. (C) identify and illustrate how changes in DNA cause mutations (and evaluate the significance of these changes). Objective 1: The student will demonstrate an understanding of the nature of science. 10.2 The student uses scientific methods during field and laboratory investigations. The student is expected to: (C) organize, analyze, evaluate, make inferences, and predict trends from data (D) communicate valid conclusions FOCUS TEKS AND STUDENT EXPECTATION: SUPPORTING TEKS AND STUDENT EXPECTATIONS: CONCEPTS Life Characteristics Unique Control Mutations ENDURING UNDERSTANDINGS/GENERALIZATIONS/PRINCIPLES The student will understand that All living things contain nucleic acids in the form of DNA and/or RNA. Nucleic acids contain the pattern for making each organism similar to others in its species. Each person’s DNA is unique to them unless the have an identical sibling. DNA is the control center for all activities in the cell including protein and replication patterns. A mutation in the DNA of a cell can cause drastic changes in the function of the cell. I. SEQUENCE OF ACTIVITIES (INSTRUCTIONAL STRATEGIES) A. Focus/connections/anticipatory set When students enter the classroom, the teacher should be wearing a set of comic nose, glasses and mustaches (like the kind you can purchase as a gag gift or at Halloween). After taking roll, the teacher should explain that “everything about you from how you look (while pointing to the glasses) to your need for glasses is controlled by the DNA pattern that your receive from your parents. This pattern was determined the instant the sperm fertilized the egg and has been copied repeatedly to make every cell in your body. Sometimes, the pattern is not copied correctly and problems may occur. This lab will show how a mutation in just one nucleotide can vastly change what is produced.” B. Instructional activities (demonstrations, lectures, examples, hands-on experiences, role play, active learning experience, art, music, modeling, discussion, reading, listening, viewing, etc.) 1. Lecture Go over vocabulary list. C. Guided activity or strategy Cut out a couple samples of the DNA pieces and show students how they are matched up by shapes. Don’t be specific on what is matching up, just show how they need to match up the complementary shapes. D. Accommodations/modifications Students requiring accommodations may be given a copy of the Instructor’s Copy – Vocabulary. E. Enrichment Students requiring enrichment may be assigned the vocabulary list as homework before the activity. II. STUDENT PERFORMANCE A. Description Complete Lab – The Pattern. B. Accommodations/modifications Students requiring accommodations should be assigned a peer tutor. C. Enrichment Students requiring enrichment may be assigned as a peer tutor. III. ASSESSMENT OF ACTIVITIES A. Description Complete Lab Worksheet – The Pattern. B. Rubrics/grading criteria All questions should be graded at 4 points each. These points should be deducted for incorrectly answered or blank questions. C. Accommodations/modifications Students requiring accommodations should not need a peer tutor on the lab questions but may need a more lenient grading scale on question 7. D. Enrichment No leniency should be given on questions. E. Sample discussion questions 1. 2. 3. 4. 5. 6. IV. What is the complementary base for adenine in DNA? Thymine What base replaced thymine in RNA? Uracil What base is the complementary base for cytosine? guanine What is the major difference between a DNA nucleotide and an RNA nucleotide? Deoxyribose sugar is in DNA and ribose sugar is in RNA. May also include uracil substitutes for thymine in RNA. Why is mRNA single-stranded? So it can leave the nucleus. Double-stranded DNA cannot fit through the nuclear membrane. What is a mutation? A permanent change in the DNA structure. TAKS PREPARATION A. Transition to TAKS context 1. On rare occasion, codons are inserted, deleted, or substituted for one another during the process of DNA replication. Biologists identify these changes in DNA molecules as ___ (a) transferences. (b) mutations. (c) replications. (d) natural selection. 2. A biology teacher lists and explains some of the mechanisms that may cause a molecules of DNA to mutate. Which of the following is a mechanism that does not belong on the list. (a) One codon is substituted for another codon in a molecule of DNA. (b) An extra codon is inserted into a molecule of DNA. (c) A codon specifies a particular amino acid in a molecule of DNA. (d) A codon is deleted from a molecule of DNA. 3. Which of the following best describes mechanisms that can cause mutations in DNA? (a) Codons are inserted, deleted, or specify a particular amino acid during the process of DNA replication. (b) Codons are deleted, substituted, or specify a particular amino acid during the process of DNA replication. (c) Codons are substituted, inserted, or specify a particular amino acid during the process of DNA replication. (d) Codons are inserted, deleted, or substituted for one another during the process of DNA replication. B. Sample TAKS questions Spring 2003 There were no questions over objective 6A on this test, only 6C and 6D. 6C 1. The diagram represents the chromosomes of a person with a genetic disorder caused by nondisjunction, in which the chromosomes fail to separate properly. Which chromosome set displays nondisjunction? (a) 2 (b) 8 (c) 21 (d) 23 2. The chain above represents three codons. Which of the following changes would be expected in the amino acid chain if the mutation shown above occurred? (a) The amino acid sequence would be shorter than expected. (b) The identity of one amino acid would change. (c) The amino acid sequence would remain unchanged. (d) The identities of more than one amino acid would change. Spring 2004 1. DNA molecules separate into single strands, which are then used to construct two identical strands of DNA. This process ensures that the ____. (a) cytoplasm is in equilibrium (b) mitochondria are genetically identical to the chloroplasts (c) parent cells use little ATP (d) daughter cells are genetically identical to the parent cells 2. 3’AATCGC5’ Which of the following nucleotide bases sequences complements the section of DNA modeled above? (a) 5’UTCGCA3’ (b) 5’TTAGCG3’ (c) 5’GCGATT3’ (d) 5’TTUCTC3’ 6C 3. Ultraviolet radiation can cause mutations in the DNA of skin cells that have been overexposed to the sun. This mutated DNA has no effect on future offspring because ____. (a) changes in skin cell DNA are homozygous recessive (b) mutations must occur within the RNA codons (c) offspring reject parental skin cells (d) only changes to gamete DNA can be inherited V. KEY VOCABULARY amino acid base complementary daughter cells DNA VI. RESOURCES A. Textbook None needed equilibrium mRNA nucleotide parent cells B. Supplementary materials/equipment Transparency master – Vocabulary Instructor’s copy – Vocabulary Lab Worksheet – The Pattern Instructor’s copy – The Pattern Pattern Pieces C. VII. Technology FOLLOW UP ACTIVITIES (reteaching, cross-curricular support, technology activities, next lesson in sequence, etc.) A. Reteaching Go over graded lab and put question 2 from the 2003 TAKS test on the board (with the square codon chart). Go over the answers with the students and make sure they know how to use both types of codon charts. B. Next lesson in sequence Biology & Chemistry – 6D – Compare genetic variations observed in plants and animals. VIII. TEACHER NOTES Before lab: 1) Make enough copies of the Lab Worksheet for each student to have one. 2) Decide how the DNA components will be run off. They can be done on paper and each student assigned to cut out his/her own set or they can be done on card stock or foam sheets and kept for later use. If card stock or foam will be used, decide whether the first group will cut them out or whether they will be cut out ahead of time. 3) Run off enough DNA components so that each student or pair of students has a set. During lab: 4) Stress that DNA is read from the 5’ to the 3’and that the codon chart is based on the m-RNA. 5) Make sure students are matching up the DNA pieces correctly.