PRINCE GEORGE’S HOSPITAL CENTER INTERNAL MEDICINE RESIDENCY PROGRAM SECTION 10: GASTROENTEROLOGY This section has been reviewed and approved by the Chief, Division of Gastroenterology as well as the Program Director, Internal Medicine Residency Program at Prince George’s Hospital Center. ________________________ Chief, Division Of Gastroenterology ______________________________ Program Director, Residency Program I. Overview Gastroenterology encompasses the evaluation and treatment of patients with disorders of the gastrointestinal tract, pancreas, biliary tract, and liver. It includes disorders of organs within the abdominal cavity and requires knowledge of the manifestations of gastrointestinal disorders in other organ systems. The general internist should have a wide range of competency in gastroenterology and should be able to provide primary and, in some cases, secondary preventive care, evaluate a broad array of gastrointestinal symptoms, and manage many gastrointestinal disorders. The general internist is not expected to perform most technical procedures with the important exception of flexible sigmoidoscopy. However, he/she must be familiar with the indications, contraindications, interpretations, and complications of these procedures. The goal of this rotation is to provide the internal medicine resident with the ability to evaluate and manage an array of gastrointestinal and hepatologic symptoms and disorders. Residents may be given an opportunity to assist faculty during select endoscopic procedures. This rotation will help residents evaluate and develop a diagnostic and therapeutic approach to patients with general gastroenterology and hepatology disorders. The residents will learn screening guidelines for colon cancer and other gastroenterologic disorders. During the rotation the residents do inpatient consults with the staff attending, observe and participate in certain procedures including endoscopies, PEG placements etc, give at least one subspecialty noon conference as well as see patients in the outpatient setting once a week with a GI attending. Resident responsibilities are detailed in Section I of the Resident Handbook. The resident is supervised for all patients by a staff Gastroenterologist for all patients. II. Principle Teaching Methods It consists of frequent encounters with the attending physician regarding patient care. The resident will discuss all patients with the attending physician and interpret clinical data to formulate a differential. The attending will assign reading topics on a regular basis and review the material with the residents. This will include accepted national guidelines as well as upcoming treatment modalities in the management of various gastroenterologic diseases. The faculty will also critique the residents consult notes, examination and management plan. Rounds will include short 15-30 minute discussions on current topics driven by patient encounters and initiated by resident and completed by the attending physician on most days. Latest information dealing with the topic as provided by literature search and pertinent articles should be discussed. Residents should become familiar with the indications and screening for Colon Cancer and other common GI diseases by the end of the rotation. The residents are also exposed to a variety of cases of viral and chemical hepatitis as well as to procedures like ERCP and MRCP. Residents are required to review a minimum number of test results with the attending on service to meet the requirements of the rotation. These requirements are listed in the logsheet at the end of this section. Residents must print a double-sided copy of the logsheet and complete the requirements and turn in the logsheet to the program coordinator at the end of the month to get credit for the rotation. All topics listed in the logsheet must be discussed in detail during the rotation. The residents must also observe and assist where applicable the attending physician during procedures like PEG placement, EGD, Colonoscopy. During the rotation the resident must present a topic during GI Conference. The topic must be discussed with the attending physician and chief residents beforehand to ensure the following spectrum of diseases are covered in the entire academic year: GI bleed- upper and lower Pancreatitis Colitis- ischemic, inflammatory, radiation Motility disorders- esophagus, intestinal, gastroparesis Hepatits- viral, alcoholic, drug induced, ischemic Malignancies- pancreatic, colon, MALT, hepatoma, metastatic disease, Diarrhea- secretory, osmotic, infectiousEnd stage liver disease HIV associated upper and lower GI infections Gall bladder and biliary duct related- gallstones, cholecystitis and cholangitis III. Strengths and Limitations The gastroenterology faculty consists of a volunteer faculty that has a strong commitment to patient care and resident education. The patient and disease exposure is broad. The residents have close interaction with the faculty with daily rounds and procedures (endoscopies, PEG placement etc.). The faculty is also easily accessable to the residents for patient care related issues during the day via phone and comes in to the hospital for any GI emergencies. The residents also gain exposure to outpatient management of GI cases by attending the weekly GI clinic at Gleridge Medical Center. The experience gained is typical of a community hospital. IV. Goals and Objectives for Gastroenterology Rotation Legend of Learning Activities Learning Venues 1. Direct Patient Care/Consultation 2. 3. 4. 5. 6. Attending Rounds Gastroenterology Clinic Self study Gastroenterology conference Core Lecture Series Evaluation Methods A. Attending Evaluations B. Direct Observation C. 360O evaluation D. Intraining examination Competency: Patient Care Demonstrate the ability to use history, physical exam, laboratory, and ancillary tests to assess the status of a patient with acute gastrointestinal hemorrhage Interview patients more skillfully, gathers accurate and essential information with emphasis on gastrointestinal illness Examine patients more skillfully with competent and complete observation of normal and abnormal signs Define and prioritize patient’s medical problems Generate and prioritize differential diagnoses with appropriate testing and therapeusis Develop rational, evidence-based management strategies Demonstrate ability to generate differential diagnosis, diagnostic strategy, and define the appropriate therapeutic plan and ongoing modifications in a patient with GI diseases Competency: Medical Knowledge Articulate the pathophysiology, evaluation and management of patients with GI diseases and their complications Expand clinically applicable knowledge base of the basic and clinical sciences underlying the care of medical service patients, both out and inpatients. Access and critically evaluate current medical information and scientific evidence relevant to patient care Competency: Interpersonal and Communication Skills Interact in an effective way with physicians and nurses participating in the care of patients requiring gastroenterology consultation and care Communicate effectively with patients and families, with particular emphasis on explanation of complex and multisystem illness and the Learning Venues ALL Evaluation methods A, B, D 1, 2, 3 A, B 1, 2, 3 A, B 1, 2, 3, 4 1, 2, 3, 4 A, B, D A, B, D 1, 2, 3, 4 A, B, D ALL A, B, D ALL A, B, D ALL A, D ALL A, B, D 1, 2, 3 A, B, C 1, 2, 3 A, B, C testing required to confirm diagnositic possibilities Present patient information concisely and clearly, verbally and in writing. Adhere to confidentiality Teach colleagues effectively Show understanding of differing patient preferences in diagnostic evaluation and management of gastrointestinal disorders Competency: Professionalism Treat team members, primary care givers, and patients with respect Actively participate in consultations and rounds Attend and participate in all scheduled conferences Demonstrate respect, compassion, integrity and altruism towards patients, families, colleagues, and all members of the health care team Demonstrate sensitivity to confidentiality, gender, age, cultural differences and disabilities Identify deficiencies in peer performance Competency: Practice Based Learning Identify limitations of medical knowledge in evaluation and management of patients with gastrointestinal disorders and use the medical literature to address these gaps Competency: Systems-Based Practice Understand and utilize the multidisciplinary resources necessary to care optimally for hospitalized and out patients and the limitations of various practice environments. Collaborate with other members of the health care team to assure comprehensive patient care Use evidence-based, cost-conscious strategies in the care of hospitalized and outpatients 1, 2, 3 A, B, C ALL 1, 2, 3 A, B, C A, B 1, 2, 3 A ,B, C 1,2 1, 2, 3 A,B Singn in on attendance sheet A, B, C 1, 2, 3 A, B, C ALL C ALL A, D ALL A, B, C 1, 2, 3 A, B, C ALL A, D V. Educational Content A. Acute GI conditions 1) Understand the differential diagnosis, appropriate tests and management of: Acute abdomen Acute appendicitis Ascites GI bleed Bowel obstruction, ischemia 2) Develop procedural skills in and interpret results of: Paracentesis Placement of nasogastric tube Fecal leukocytes Test for occult blood B. Esophagus 1) Understand the differential diagnosis, appropriate tests and management of: Barrett’s esophagus Squamous and adeno carcinoma, Esophagitis – acid and other (Monilia, CMV, etc.) Motility Disorders Varices 2) Interpret results of: 24-hour esophageal pH monitoring Bernstein test Contrast studies (including upper gastrointestinal series, small-bowel follow through, barium enema) Esophageal manometry C. Stomach and Duodenum 1) Understand the differential diagnosis, appropriate tests and management of: Ulcer disease Hiatal hernia illness Foreign body and Bezoar Gastritis – drugs, H. pylori and stress Motility disorders and mitotic disease Malignancy 2) Interpret results of: Assays for Helicobacter pylori Biopsy of the gastrointestinal mucosa Upper endoscopy Scans of gastric emptying Gastric acid analysis, serum gastrin level, secretin stimulation test D. Intestine 1) Understand the pathophysiology of: Motility Digestion and absorption 2) Understand the differential diagnosis, appropriate tests and management of: Infection, Malabsorption Short bowel syndrome, bacterial overgrowth HIV illness Obstruction and pseudo-obstruction Tumors Inflammatory Bowel disease 3) Interpret results of: Colonoscopy Computed tomography, magnetic, resonance imaging, ultrasound of the abdomen Culture of stool for ova, parasites D-xylose absorption test and other small bowel absorption tests Endoscopic retrograde cholangiopancreatography Examination for stool for ova, parasites Fecal electrolytes Fecal osmolality Mesenteric arteriography Qualitative and quantitative stool fat Serum B12 and Schilling tests Tumor markers E. Colon and Rectum 1) Understand the differential diagnosis, appropriate tests and management of: Inflammatory Bowel disease Angiodysplasia Irritable Bowel Syndrome Diverticulosis, diverticulitis, Colitis – (viral, bacterial, collagenous, lymphocytic, etc.) Cancer Polyposis syndromes Hemorrhoids Anusitis Appendiceal disease 2) Interpret results of: Lactose and hydrogen breath tests Colonoscopy Flexible sigmoidoscopy Laxative screen F. Liver 1) Understand the differential diagnosis, appropriate tests and management of: Fatty liver, NASH, cirrhosis Cholestasis Viral hepatitis, use of Interferon Portal hypertension – TIPS, banding, surgery Ascites Hepatic encephalopathy Hepato-renal syndrome Autoimmune hepatitis Drug induced and alcoholic disease Hemochromatosis Polycystic disease Abscesses (bacterial an Amebic) Liver carcinoma, metastatic disease to the liver Transplantation 2) Interpret results of: Computed tomography, magnetic resonance imaging, ultrasound of the abdomen Blood tests for autoimmune, cholestatic, genetic liver diseases Viral hepatitis serology, Liver function tests Discriminant function Liver biopsy Percutaneous transhepatic cholangiography, ERCP, MRCP G. Biliary Tract Disease 1) Understand the differential diagnosis, appropriate tests and management of: Acute cholecystitis Biliary obstruction Cholangitis iincluding Sclerosing cholangitis Primary biliary cirrhosis Cholelithiasis 2) Interpret results of: Gall bladder radionuclide scan Percutaneous transhepatic cholangiography, ERCP, MRCP Autoimmune serologies Liver function tests H. Pancreas 1) Understand the differential diagnosis, appropriate tests, and management of: Acute pancreatitis and its complications Chronic pancreatitis and its complications Pancreatic cancer 2) Understand and interpret results of: Amylase and lipase CT scans of the abdomen ERCP, MRCP 3) Understand indications for ERCP, stents and radiation therapy I. Miscellaneous 1) Peritonitis 2) HIV disease and its affect on various GI organs 3) Approach to patient with: Nausea and vomiting Abdominal pain Diarrhea Constipation GI bleeding, appropriate tests and management including bleeding scan 4) Endoscopy relating to GI illness and effects of therapeutic procedures (polypectomy, sphincterotomy, etc.) 5) Pathology and its relation to GI disease – biopsy interpretation, stool for O & P, duodenal drainage, liver biopsy, cytology, etc. 6) Gastrointestinal manifestation of diabetes, chronic renal disease 7) Gastrointestinal care in the surgical patients VI. Recommended Readings All senior residents are encouraged to read the MKSAP for Gastrenterology during their one-month rotation. Questions will help develop analytical thinking. Residents should also consult Harrison’s Principles of Internal Medicine. Residents are also encouraged to read from MDConsult and Up To Date on a case by case basis. Other recommended readings are as follows: 1) Bounds BC and Friedman LS. Lower gastroeintestinal bleeding. Gastroenterol Clin North Am. 2003 Dec;32(4):1107-25. 2) Swaroop VS. Colonoscopy as a screening test for colorectal cancer in average-risk individuals. Mayo Clin Proc. 2002; 77: 951-956 3) Tremaine WJ. Practice guidelines for inflammatory bowel disease: an instrument for assessment. Mayo Clin Proc. 1999; 74: 495-501 4) Podolsky DK. Inflammatory bowel disease. NEJM, Aug 8, 2002; 347(6): 417-429 5) Farrell RJ and Kelly CP. Celiac sprue. N Engl J Med. 2002 Jan 17;346(3):180-8 6) Tamboli PC. Current medical therapy for chronic inflammatory bowel diseases. Surg Clin N Am 87 (2007), 697-725 7) Szarka LA. Diagnosing gastroesophageal reflux disease. Mayo Clin Proc. 2001; 76: 97-101 8) Arora AS. Medical therapy for gastroesophageal reflux disease. Mayo Clin Proc. 2001; 76: 102-106 9) Huang CS and Lichtenstein DR. Nonvariceal upper gastrointestinal bleeding. Gastroenterol Clin North Am. 2003 Dec;32(4):1053-78 10) Mertz HR. Irritable bowel syndrome. N Engl J Med. 2003 Nov 27;349(22):2136-46. 11) Shiotani A and Graham DY. Pathogenesis and therapy of gastric and duodenal ulcer disease. Med Clin North Am. 2002 Nov;86(6):1447-66 12) Suerbaum S and Michetti P. Helicobacter pylori infection. N Engl J Med. 2002 Oct 10;347(15):1175-86 13) Ragni et al. Survival of Human Immunodeficiency virus-Infected liver transplant recipients. JID 2003: 188 (15 Nov) 1412-1420 14) Torriani et al. Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C virus infection in HIV-infected patients. NEJM 2004; 351: 438-450 15) Imperiale et al. Fecal DNA versus Fecal Occult Blood for Colorectal-Cancer screening in an Average-risk Population. NEJM 351; 26: 2704-2714 16) Bjelakovic et al. Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis. The Lancet vol 364: 1219-1228 17) Marik P and Zaloga G. Meta-analysis of parenteral nutrition versus enteral nutrition in patients with acute pancreatitis. BMJ vol 328: 1407-1410 18) Moayyedi et al. An update of the Cochrane Systematic review of Helicobacter Pylori eradication therapy in nonulcer dyspepsia: Resolving the discrepancy between systematic reviews. AM J Gastroenterology. Vol 98 No. 12, 2003: 2621-2626 19) Wong B et al. Helicobacter Pylori eradication to prevent gastric cancer in a high-risk region of China. JAMA Jan 14,2004. Vol 291, No 2: 187-194 20) Isenmann R et al. Prophylactic antibiotic treatment in patients with predicted severe acute pancreatitis: A placebo-controlled, double-blind trial. Gastroenterology 2004; 126: 997-1004 21) Moayyedi et al. The efficacy of proton pump inhibitors in nonulcer dyspepsia: A systematic review and economic analysis. Gastroenterology 2004; 127: 1329-1337 22) Whitcomb D. Acute Pancreatitis. NEJM 354; 20, May 18,2006: 2142-2150 23) Mannon P et al. Anti-interleukin-12 antibody for active Crohn’s disease. NEJM 351; 20, Nov 11, 2004: 2069-2079 24) Krawitt E. Autoimmune hepatitis. NEJM 354; 1, Jan 5, 2006: 54-66 25) Mukherjee S et al. Beta-Blockers to prevent Esophageal varices- An unfulfilled promise. NEJM 353; 21, Nov 2005: 2288-2290 26) Gines P et al. Management of cirrhosis and ascites. NEJM, Apr 15 2004; 350(16): 1646-1654 27) Binder H. Causes of Chronic diarrhea. NEJM 355; 3, July 2006: 236-239 28) Schoenfeld P et al. Colonoscopic screening of average-risk women for colorectal neoplasia. NEJM 352; 20, May 2005: 2061-2068 29) Musher D and Musher B. Contagious acute gastrointestinal infections. NEJM 351; 23, Dec 2004: 2417-2427 30) Navarro V, Senior J. Drug-related hepatotoxicity. NEJM 354; 7, Feb 2006: 731-739 31) Hoofnagle J. Hepatitis B – Preventable and now treatable. NEJM 354;10, March 2006: 1074-1076 32) Liaw Y et al. Lamivudine for patients with chronic hepatitis B and advanced liver disease. NEJM 351; 15, Oct 2004: 1521-1531 33) Poland G, Jacobson R. Prevention of Hepatitis B with the Hepatitis B Vaccine. NEJM 351; 27, Dec 2004: 2832-2838 34) Hampel H et al. Screening for the Lynch syndrome (Hereditary nonpolyposis colorectal cancer). NEJM 352; 18, May 2005: 1851-1860 35) Meyerhardt J, Mayer R. Systemic therapy for colorectal cancer. NEJM 352; 5, Feb 2005: 476-487 36) Suk-Fong A. The maze of treatments for Hepatitis B. NEJM 352; 26, Jun 2005: 27432746 PRINCE GEORGE’S HOSPITAL CENTER INTERNAL MEDICINE RESIDENCY PROGRAM GASTROENTEROLOGY LOGSHEET RESIDENT NAME______________________________________________ PGY LEVEL_______________ PANCREATITIS MR# Assessment and Plan Discussed with resident Comment by supervising attending (Resident diagnosis correct/not, missed findings etc) SIGNATURE of Supervising attending & DATE MR# Assessment and Plan Discussed with resident Comment by supervising attending (Resident diagnosis correct/not, missed findings etc) SIGNATURE of Supervising attending & DATE MR# Assessment and Plan Discussed with resident ROTATION MONTH_____________ BILIARY DISEASES GI BLEED DIARRHEA & MOTILITY DISORDERS Comment by supervising attending (Resident diagnosis correct/not, missed findings etc) SIGNATURE of Supervising attending & DATE RESIDENT NAME:___________________________________________ TEST MR# Resident’s diagnosis and plan Comment by supervising attending (correct/not, missed findings etc) SIGNATURE of Supervising attending & DATE MR# Resident’s diagnosis and plan Comment by supervising attending (correct/not, missed findings etc) SIGNATURE of Supervising attending & DATE MR# Resident’s diagnosis and plan Comment by supervising attending (correct/not, missed findings etc) SIGNATURE of Supervising attending & DATE MR# HEPATITIS PROFILE POLYP BIOPSY RESULT ABDOMEN CT SCAN ASCITIC FLUID / IBD FINDINGS Resident’s diagnosis and plan Comment by supervising attending (correct/not, missed findings etc) SIGNATURE of Supervising attending & DATE