POLYMYALGIA RHEUMATICA TREATMENT INFORMATION FOR PATIENTS What is Polymyalgia Rheumatica (PMR)? Polymyalgia Rheumatica is a condition that causes pain and stiffness around the shoulders and hips, particularly in the morning. The exact cause is unknown. Diagnosis can be difficult and is usually based on your symptoms rather than a specific blood test. Treatment The only successful treatment is with steroids (prednisolone). These tablets are taken by mouth each morning with your breakfast. Different strength tablets are as follows: One red tablet = 5mg, One brown tablet = 2.5mg, One white tablet = 1mg You will need about 2 years of treatment. The dose should be reduced slowly and the table below shows how you can do this. Sometimes it is not possible to follow the table exactly but you can work with your GP to decide how much steroid you require. If you cannot get below 10mg (2 red tablets) after 4 months of treatment then there may be a different diagnosis and you should see your GP again. It is usually best to go by your symptoms rather than by monitoring any blood tests. Try and get onto the lowest dose possible without your symptoms coming back. This dose will gradually go down as the months go by. If there is a recurrence of symptoms, try going up by 1 – 2mg rather than by 5mg. What about side effects? There are many possible side effects with steroid treatment. We try and reduce the risk of side effects by using the lowest dose possible to control your symptoms. An information leaflet on steroids is available for you. One side effect we can protect against is loss of bone. If you are over 65 years old you should have a weekly tablet to protect your bones along with a daily calcium and vitamin D tablet taken either once or twice a day. If you are under 65 years old, you should have a bone density scan to decide on the best treatment. Your GP will get the result of the scan. TREATMENT SCHEDULE Dose Treatment period 15mg 12.5mg 10mg 9mg 8mg 7mg 4 weeks 4 weeks 4 weeks 4 weeks 4 weeks 4 weeks Continue to decrease by 1mg monthly to lowest possible dose then leave for several months before trying to lower further If you have any questions regarding your condition or your treatment, contact: Your GP The Rheumatology Department (01592 648193 – and leave a message, someone will return your call within 2 working days). Updated April 2010 Version 1 due for review April 2011