Forensic Science Toxicology Notes 11.20.08 Deaths investigated by Forensic Toxicologists: Questions addressed by Toxicologist: Is a ________________________ present? If so, ___________________________________? How much of the substance is present? Is the concentration great enough to __________________________________________________? How was__________________________________________________? Properties of an Ideal Poison: Potencies of Various Poisons: Agent Lethal Dose General Classes of Poisons: Gases – Metallic Poisons – Non-volatile organics: o o o o Carbon Monoxide (CO) Normal level of _________ in body (up to _______________________) Fatal level at autopsy considered to be _________________________ ______________________________________. CO prevents ________________________________________________ ____________________________________. o Leads to _______________________ o CO victims have _________________________ Metal Poisons Most common: Death within __________________ Can be given _________________________________________________ Symptoms: o o Alkaloids Nitrogen-containing organic base Found in plants and fungi o Strychnine most common Death from ________________________________ ___________________________________________ ___________________________________________ Pesticides Many of the pesticides we spray on our lawns, gardens, etc. are poisonous Growing in popularity o o Toxicological Analysis of Tissues A. B. C. Begin analysis as quickly as possible after death due to ___________ ________________________________________________________ D. Look for traces of poison OR _________________________________ ________________________________________________________ Samples collected at Autopsy Fluids Soft Tissue Intentional Poisoning Trends Perpetrator Profile Gender Top 5 Homicidal Poisons Possible Symptoms __________________________ (opioids, organic phosphates) __________________________ (arsenic – smell of garlic) __________________________ (Thallium) __________________________ (Strychnine) ___________________________(Botulism) ___________________________ (depressants, hypnotics) ___________________________ (CO=_______, nitrites=________) ___________________________ (arsenic = __________________) (dioxin=_________________)