TECHNICAL APPENDIX

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Online Appendix for the following July 4 JACC article
TITLE: Post-Reperfusion Myocardial Infarction: Long-Term Survival Improvement
Using Adenosine Regulation With Acadesine
AUTHORS: Dennis T. Mangano, PhD, MD, Yinghui Miao, MD, MS, Iulia C. Tudor,
PhD, Cynthia P. Dietzel, MD, for the investigators of McSPI Research Group and the
IREF
APPENDIX
The Multicenter Study of Perioperative Ischemia (McSPI) Research Group is a
consortium of investigators from approximately 150 worldwide medical centers, focusing
on the problems of perioperative myocardial infarction, stroke, renal dysfunction, as well
as other organ dysfunction, and the implications of such diseases for health economics.
The Ischemia Research and Education Foundation (IREF) is a non-profit foundation
which is closely affiliated with the McSPI investigators and their institutions.
Analysis Group: Dennis T. Mangano, PhD, MD; Yinghui Miao, MD, MPH; Iulia C.
Tudor, PhD; Cynthia P. Dietzel, MD (IREF).
Editorial / Administrative Assistants: Diane Beatty (IREF), Brenda Xavier (IREF), Iris
Lei (IREF).
Participating Medical Centers in Acadesine 1024 / Investigators:
United States: Allegheny General Hospital, Pittsburgh, PA (Richard Clark, MD),
Baystate Medical Center, Springfield, MA (Richard Engelman, MD), Beth Israel
Hospital, Boston, MA (Mark Comunale, MD), Brigham & Women’s Hospital, Boston,
MA (Simon Body, MD, Rosemarie Maddi, MD), Carraway Methodist Hospital,
Birmingham, AL (William Lell, MD, Constantine Athanasuleas, MD), Cedars-Sinai
Medical Center, Los Angeles, CA (Arnold Friedman, MD), Cleveland Clinic Foundation,
Cleveland, OH (Norman Starr, MD), Creighton Cardiac Center, Omaha, NE (Syed
Mohiuddin, MD), Deborah Heart & Lung Center, Brown Mills, NJ (Mark Adkins, MD),
Duke University Medical Center, Durham, NC (Mark Newman, MD; Thomas Stanley,
MD), Emory University Hospital, Atlanta, GA (Christina Mora Mangano, MD [currently
at Stanford University Medical Center, Palo Alto, CA], Jamie Ramsay, MD), Florida
Hospital, Orlando, FL (H.B. Karunaratne, MD), Hahnemann University Hospital,
Philadelphia, PA (Joel Bennett, DDS, MD), Kaiser Foundation Hospital, San Francisco,
CA (Wayne Bellows, MD), Milstein Hospital, College of Physicians and Surgeons, New
York, NY (Ellise Delphin, MD, MPH, Edward Miller, MD), Tufts-New England Medical
Center, Boston, MA (George Gordon, MD), New York University Medical Center, New
York, NY (Susan Paglia, MD), North Carolina Baptist Hospital, Winston-Salem, NC
(Roger Royster, MD), Sinai-Samaritan Medical Center, Milwaukee, WI (Yoseph Shalev,
MD), St. Francis Hospital, Tulsa, OK (Charles McEntee, MD), St. Joseph Hospital,
Orange, CA (William Ostermiller, MD), St. Luke’s-Roosevelt Hospital Center, New
York, NY (Zak Hillel, PhD, MD), St. Vincent Hospital and Health Science Center,
Indianapolis, IN (John Schier, MD), SUNY Health Science Center at Brooklyn, NY
(Ashraf Boutros, MD), UCLA School of Medicine, Los Angeles, CA (John Williams,
MD), University of Alabama at Birmingham, Birmingham, AL (Paul Samuelson, MD),
University of Michigan Medical Center, Ann Arbor, MI (Joyce Wahr, MD), University of
Pittsburgh Medical Center, Pittsburgh, PA (Brack Hattler, MD), University of Rochester
School of Medicine and Dentistry, Rochester, NY (David Stern, MD, Pratima Shah,
MD), University of Washington Medical Center, Seattle, WA (Bruce Spiess, MD),
Veterans Administration Medical Center, Albuquerque, NM (Fabrizio Follis, MD),
Veterans Administration Medical Center, Milwaukee, WI (David Warltier, MD, PhD)
Veterans Administration Medical Center, Portland, OR (Richard Davis, MD), Veterans
Administration Medical Center, San Diego, CA (Riyad Tarazi, MD), Veterans
Administration Medical Center, San Francisco, CA (Jacqueline Leung, MD, Gerard
Ozanne, MD), Virginia Mason Medical Center, Seattle, WA (Julia Pollock, MD), Walter
Reed Army Medical Center, Washington, DC (John Fontana, MD), Western
Pennsylvania Hospital, Pittsburgh, PA (Alan Gradman, MD), Yale University School of
Medicine, New Haven, CT (Joseph Mathew, MD).
Canada: Health Science Centre, University of Manitoba, Winnipeg, Manitoba (Peter
Duke, MD), Hôtel-Dieu de Québec, Québec (Dr. Pascal Labrecque), Institut de
Cardiologie de Montreal, Montreal, Québec (L. Conrad Pelletier, MD), Laval Hospital,
Ste-Foy, Quebec (Jacques Metras, MD), Plains Health Center, Regina, Saskatchewan
(Edward Busse, MD), Queens University, Kingston, Ontario (Ronald Seegobin, MD),
Royal Victoria Hospital, Montreal, Quebec (Fiona Ralley, MD), St. Boniface General
Hospital, Winnipeg, Manitoba (Ian Thomson, MD), St. Michael’s Hospital, Toronto,
Ontario (David Mazer, MD), The Toronto Hospital, Toronto, Ontario (Richard Weisel,
MD), University Hospital, London, Ontario (John Murkin, MD, FRCPC), University of
Ottawa Heart Institute, Ottawa, Ontario (W. Keon, OC, MD, FRCS), Vancouver General
Hospital, Vancouver, B.C. (W. R. Eric Jamieson, MD), Victoria General Hospital,
Halifax, Nova Scotia (C. Edwin Kinley, MD), Walter Mackenzie Health Sciences Center,
Edmonton, Alberta (Arvind Koshal, MD).
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