Online Appendix for the following July 4 JACC article TITLE: Post-Reperfusion Myocardial Infarction: Long-Term Survival Improvement Using Adenosine Regulation With Acadesine AUTHORS: Dennis T. Mangano, PhD, MD, Yinghui Miao, MD, MS, Iulia C. Tudor, PhD, Cynthia P. Dietzel, MD, for the investigators of McSPI Research Group and the IREF APPENDIX The Multicenter Study of Perioperative Ischemia (McSPI) Research Group is a consortium of investigators from approximately 150 worldwide medical centers, focusing on the problems of perioperative myocardial infarction, stroke, renal dysfunction, as well as other organ dysfunction, and the implications of such diseases for health economics. The Ischemia Research and Education Foundation (IREF) is a non-profit foundation which is closely affiliated with the McSPI investigators and their institutions. Analysis Group: Dennis T. Mangano, PhD, MD; Yinghui Miao, MD, MPH; Iulia C. Tudor, PhD; Cynthia P. Dietzel, MD (IREF). Editorial / Administrative Assistants: Diane Beatty (IREF), Brenda Xavier (IREF), Iris Lei (IREF). Participating Medical Centers in Acadesine 1024 / Investigators: United States: Allegheny General Hospital, Pittsburgh, PA (Richard Clark, MD), Baystate Medical Center, Springfield, MA (Richard Engelman, MD), Beth Israel Hospital, Boston, MA (Mark Comunale, MD), Brigham & Women’s Hospital, Boston, MA (Simon Body, MD, Rosemarie Maddi, MD), Carraway Methodist Hospital, Birmingham, AL (William Lell, MD, Constantine Athanasuleas, MD), Cedars-Sinai Medical Center, Los Angeles, CA (Arnold Friedman, MD), Cleveland Clinic Foundation, Cleveland, OH (Norman Starr, MD), Creighton Cardiac Center, Omaha, NE (Syed Mohiuddin, MD), Deborah Heart & Lung Center, Brown Mills, NJ (Mark Adkins, MD), Duke University Medical Center, Durham, NC (Mark Newman, MD; Thomas Stanley, MD), Emory University Hospital, Atlanta, GA (Christina Mora Mangano, MD [currently at Stanford University Medical Center, Palo Alto, CA], Jamie Ramsay, MD), Florida Hospital, Orlando, FL (H.B. Karunaratne, MD), Hahnemann University Hospital, Philadelphia, PA (Joel Bennett, DDS, MD), Kaiser Foundation Hospital, San Francisco, CA (Wayne Bellows, MD), Milstein Hospital, College of Physicians and Surgeons, New York, NY (Ellise Delphin, MD, MPH, Edward Miller, MD), Tufts-New England Medical Center, Boston, MA (George Gordon, MD), New York University Medical Center, New York, NY (Susan Paglia, MD), North Carolina Baptist Hospital, Winston-Salem, NC (Roger Royster, MD), Sinai-Samaritan Medical Center, Milwaukee, WI (Yoseph Shalev, MD), St. Francis Hospital, Tulsa, OK (Charles McEntee, MD), St. Joseph Hospital, Orange, CA (William Ostermiller, MD), St. Luke’s-Roosevelt Hospital Center, New York, NY (Zak Hillel, PhD, MD), St. Vincent Hospital and Health Science Center, Indianapolis, IN (John Schier, MD), SUNY Health Science Center at Brooklyn, NY (Ashraf Boutros, MD), UCLA School of Medicine, Los Angeles, CA (John Williams, MD), University of Alabama at Birmingham, Birmingham, AL (Paul Samuelson, MD), University of Michigan Medical Center, Ann Arbor, MI (Joyce Wahr, MD), University of Pittsburgh Medical Center, Pittsburgh, PA (Brack Hattler, MD), University of Rochester School of Medicine and Dentistry, Rochester, NY (David Stern, MD, Pratima Shah, MD), University of Washington Medical Center, Seattle, WA (Bruce Spiess, MD), Veterans Administration Medical Center, Albuquerque, NM (Fabrizio Follis, MD), Veterans Administration Medical Center, Milwaukee, WI (David Warltier, MD, PhD) Veterans Administration Medical Center, Portland, OR (Richard Davis, MD), Veterans Administration Medical Center, San Diego, CA (Riyad Tarazi, MD), Veterans Administration Medical Center, San Francisco, CA (Jacqueline Leung, MD, Gerard Ozanne, MD), Virginia Mason Medical Center, Seattle, WA (Julia Pollock, MD), Walter Reed Army Medical Center, Washington, DC (John Fontana, MD), Western Pennsylvania Hospital, Pittsburgh, PA (Alan Gradman, MD), Yale University School of Medicine, New Haven, CT (Joseph Mathew, MD). Canada: Health Science Centre, University of Manitoba, Winnipeg, Manitoba (Peter Duke, MD), Hôtel-Dieu de Québec, Québec (Dr. Pascal Labrecque), Institut de Cardiologie de Montreal, Montreal, Québec (L. Conrad Pelletier, MD), Laval Hospital, Ste-Foy, Quebec (Jacques Metras, MD), Plains Health Center, Regina, Saskatchewan (Edward Busse, MD), Queens University, Kingston, Ontario (Ronald Seegobin, MD), Royal Victoria Hospital, Montreal, Quebec (Fiona Ralley, MD), St. Boniface General Hospital, Winnipeg, Manitoba (Ian Thomson, MD), St. Michael’s Hospital, Toronto, Ontario (David Mazer, MD), The Toronto Hospital, Toronto, Ontario (Richard Weisel, MD), University Hospital, London, Ontario (John Murkin, MD, FRCPC), University of Ottawa Heart Institute, Ottawa, Ontario (W. Keon, OC, MD, FRCS), Vancouver General Hospital, Vancouver, B.C. (W. R. Eric Jamieson, MD), Victoria General Hospital, Halifax, Nova Scotia (C. Edwin Kinley, MD), Walter Mackenzie Health Sciences Center, Edmonton, Alberta (Arvind Koshal, MD).