The City College of New York
Department of Chemistry
Chemistry 243: Quantitative Analysis
Professor Issa Salame
Class Time and Days: 11:00 am – 12:15 pm, Mondays and Wednesdays
Class Location: MR 1307
Telephone: (212) 650 – 6924
Office Location: MR 1224
Email address: Prof.salame@gmail.com
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Catalog Description:
Volumetric, Spectrophotometric, Electrochemical and Chromatographic Analyses
Prerequisites:
Chem 10401
Co-requisites:
Hours/Credits:
7 hours per week, 3 LECT., 4 LAB - 4 credits
Textbook:
Analytical Chemistry: An Introduction, 7th ed. by D.A.
Skoog, D. M. West, F. J. Holler and S.R. Crouch (1999)
General Objective:
This course intends to introduce the bases of analytical chemistry for chemistry and biochemistry
majors. The emphasis is put either on understanding the theoretical aspects of quantitative
analysis or problem solving skills.
LEARNING GOALS:
Students should:

Know the physical bases for analytical methods discussed during the course and
understand them

Be aware of the sources of errors and have knowledge how to avoid them

Know how to calculate the amount of analyte in the specific application of each
method

Know how to obtain calibration curve and how to use it for an analytical purpose

Know the criteria, which are used for choosing the methods for a particular analysis.
CONCEPTUAL THINKING OBJECTIVES:

Reading: cause-effect logic, hypothesis testing, summarizing logic

Writing: cause-effect links, objective designing, experiment planning

Data analysis: relevant data sources, data treatment, qualitative and quantitative
evaluation, data consistency, error analysis

Models: cause-effect, correlation, trends
LEARNING ACTIVITIES:

Text reading

Class‐time (lecture)

Hand on experience (laboratory)
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



Group discussion
Computer‐aid instruction
Problem solving (individual)
Student‐instructor consulting
STUDENT LEARNING OUTCOMES
The objectives of this course contribute to the following
departmental educational outcomes:
1. Define the physical and chemical principles of volumetric,
gravimetric, electrochemical and basic spectroscopic methods (AA,
AE, FTIR).
2. Identify which analytical method should be used to quantitatively
determine certain level of a target analyte in various matrices.
3. Define the principles and goals of analytical separations
including chromatographic techniques ( GC, HPLC),
4. Understand multiple equilibria in solutions and effectively use
chemical equilibrium toward determination of the target analyte
conc.
5. Understand the significance of the random and systematic errors,
know the ways to minimize/avoid them, and use the basic statistical
evaluation of errors (standard deviation, variation, t-test, Qtest).
6. Understand and apply the purpose, principle and significance of
calibration techniques for quantitative determination of analyte.
7. Describe in terms of chemical reactions and equilibrium
constants all steps used to quantitatively determine the
concentration of analyte
8. Successfully perform volumetric, gravimetric, spectroscopic and
chromatographic determination of the target analyte concentration
and evaluate the experimental error.
9. Write a laboratory report including data and error analysis.
Department
outcomes
a
a, j
a
a, e
a, c, d, e
a
a, e
a, b, c, i
g, i, k
Assessment tools:
The final grade is calculated as follows:
Best three scores of the four in-class examinations (35%)
Quizzes
(10%)
Final Exam
(30%)
Laboratory
(25%)
* The lowest grade exam will be dropped. Missing an exam will result in receiving a zero grade
for that particular exam and thus dropping that grade. There will not be any Make-up Exams.
Office Hours:
Mondays and Wednesday
1:00 pm – 3:00 pm
Or by appointment
Office is located in the science building in room MR 1224
Absence Policy (Attendance)
Students are expected to attend every class session of each course in which they are enrolled and
to be on time. An instructor has the right to drop a student from a course for excessive absence.
Students are advised to determine the instructor’s policy at the first class session. They should
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note that an instructor may treat lateness as equivalent to absence. (No distinction is made
between excused and unexcused absences.) Each instructor retains the right to establish his or
her own policy, but students should be guided by the following general College policy: In
courses designated as clinical, performance, laboratory or field work courses, the limit on
absences is established by the individual instructor. For all other courses, the number of hours
absent may not exceed twice the number of contact hours the course meets per week. When a
student is dropped for excessive absence, the Registrar will enter the grade of WU.
Statement on Academic Integrity
The CCNY policy on academic integrity will be followed in this course. The document can be
found through the CCNY website by clicking on Current Students  Academic Services 
Policy on Academic Integrity. All students must read the details regarding plagiarism and
cheating in order to be familiar with the rules of the college. Cases where academic integrity is
compromised will be prosecuted according to these rules. In addition, the Policy of Academic
Integrity can be found in the Undergraduate Bulletin 2007-2009 in Appendix B.3 on page 312.
Disability
In compliance with CCNY policy and equal access laws, appropriate academic accommodations
are offered for students with disabilities. Students must first register with The AccessAbility
Center for reasonable academic accommodations. The AccessAbility Center is located in the
North Academic Center, Rm. 1/218. Tel: (212) 650-5913. Under The Americans with Disability
Act, an individual with a disability is a person who has a physical or mental impairment that
substantially limits one or more major life activities. If you have any such issues, I encourage
you to visit the AccessAbility Center to determine which services may be appropriate for you.
Courtesy
Noise and excessive chatter, eating, drinking, or use of unauthorized electronic equipment is not
allowed in the classroom.
Make-up examination for INC grades
INC may be assigned to students who have a passing grade (average on all the exams) in the
course but who are unable to take the final examination due to conflict with another scheduled
examination, death of spouse, injury sustained in a catastrophic incident, etc. (proof is also
required). An Incomplete Grade Agreement form must be signed by the Instructor before the
student is allowed to take the makeup exam. Payment of a fee at the Bursar's office is required
in order to take the makeup examination. Makeup exam for INC grades in Chemistry courses
will be completed no later than two weeks after the end of classes.
DATE CHAPTERS and High priority areas
Class Schedule
August 27th
Monday
Chapter 5. Errors in Chemical Analysis
Chapter 6. Random Errors in Chemical Analysis
August 29th
Wednesday
Chapter 7. Application of Statistics to Data Treatment
September 3rd
Monday
*** NO CLASSES *** College Closed ***
Labor Day
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September 5th
Wednesday Chapter 11. Titrimetric Methods of Analysis
September 10th
Monday
Chapter 4. Aqueous Solution Chemistry
September 12th
Wednesday Chapter 9. Effect of Electrolyte on Chemical Equilibria
September 17th
Monday
*** NO CLASSES *** College Open ***
September 19th
Wednesday Chapter 10. Application of Equilibrium Calculations to Complex Systems
September 24th
Monday
Catch-Up and Review for first examination
September 26st
Wednesday *** NO CLASSES *** College Open ***
October 1st
Monday
*** FIRST EXAMINTION ***
October 3rd
Wednesday
Chapter 12. Theory of Neutralization Titration
October 8th
Monday
October 10th
Wednesday
*** NO CLASSES *** College Closed ***
Columbus Day
Monday Schedule
Chapter 13. Titration Curves for Complex Acid/Base Systems
October 15th
Monday
Chapter 13. Titration Curves for Complex Acid/Base Systems
October 17th
Wednesday
Chapter 14. Application of Neutralization Titrations
October 22nd
Monday
Chapter 15. precipitation Titrimetry: Complex Formation Titration
October 24th
Wednesday
Catch-up and Review for Second Examination
October 29th
Monday
*** SECOND EXAMINTION ***
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October 31st
Wednesday
Chapter 16. Introduction to Electrochemistry
November 5th
Monday
Chapter 17. Application of Standard Electrode potential
November 7th
Wednesday Chapter 18. Application of Oxidation Reduction Titration
November 12th
Monday
Chapter 19. Potentiometry
November 14th
Wednesday Chapter 20. Other Electroanalytical Methods
November 19th
Monday
*** THIRD EXAMINATION ***
November 21st
Wednesday Chapter 21. Introduction to Spectrochemical Methods
Chapter 23. Molecular Absorption Spectroscopy
November 26th
Monday
Chapter 23. IR and Atomic Spectroscopy
November 28th
Wednesday Chapter 24. Analytical Separations
December 3rd
Monday
Chapter 24F. An Introduction to Chromatographic Methods
December 5th
Wednesday Chapter 25A. Gas Liquid Chromatography
Chapter 25 BC. High Performance Liquid Chromatography
Chapter 26 A. High Performance Liquid Chromatography
December 10th
Monday
*** FOURTH EXAMINATION ***
December 12th
Wednesday Summary of Analytical Methods
Final Examination will be scheduled during the final exam period between Thursday the 14th
and Thursday the 21st of December of 2012. Our scheduled final examination date is the 19th of
December from 10:30 am until 12:45 pm.
Study Guides:
1. Plan at least three hours of study (reading the chapter and completing the problem sets “homework”) time for every hour you spend in class.
2. Do the problem sets individually (without help from friends or classmates) initially.
Please look at a related problem in the solution manual to help you solve the assigned
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problem. If you are still unable to solve the problem, then ask a friend, classmate,
workshop leader, TA, or Professor for help.
3. Read the book and take notes as you read.
4. Seek help when you have difficulty (office hours, tutoring, study groups).
“I hear, I forget. I see, I remember. I do, I understand.”
Chinese proverb
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