HEP_24613_sm_SuppReferences

advertisement
Supporting References
6. Yoon SM, Gerasimidou D, Kuwahara R, Hytiroglou P, Yoo JE, Park YN, et al. Epithelial
cell adhesion molecule (EpCAM) marks hepatocytes newly derived from stem/progenitor
cells in humans. Hepatology 2011;53:964-973.
7. Zhang L, Theise N, Chua M, Reid LM. The stem cell niche of human livers: symmetry
between development and regeneration. Hepatology 2008;48:1598-1607.
8. Crawford AR, Lin XZ, Crawford JM. The normal adult human liver biopsy: a quantitative
reference standard. Hepatology 1998;28:323-331.
9. van den Heuvel MC, de Jong KP, Boot M, Slooff MJ, Poppema S, Gouw AS. Preservation
of bile ductules mitigates bile duct loss. Am J Transplant 2006;6:2660-2671.
10. van den Heuvel MC, de Jong KP, van der Horst ML, Poppema S, Slooff MJ, Gouw AS.
Impaired regeneration of biliary cells in human chronic liver allograft rejection. Special
emphasis on the role of the finest branches of the biliary tree. Liver Transpl 2004;10:2835.
11. Alvaro D, Mancino MG, Glaser S, Gaudio E, Marzioni M, Francis H, et al. Proliferating
cholangiocytes: a neuroendocrine compartment in the diseased liver. Gastroenterology
2007;132:415-431.
12. Desmet VJ. Ductal plates in hepatic ductular reactions. Hypothesis and implications. III.
Implications for liver pathology. Virchows Arch 2011;458:271-279.
13. Turanyi E, Dezso K, Csomor J, Schaff Z, Paku S, Nagy P. Immunohistochemical
classification of ductular reactions in human liver. Histopathology 2010;57:607-614.
14. Craig CE, Quaglia A, Selden C, Lowdell M, Hodgson H, Dhillon AP. The histopathology
of regeneration in massive hepatic necrosis. Semin Liver Dis 2004;24:49-64.
15. Xiao SY, Lu L, Wang HL. Fibrosing cholestatic hepatitis: clinicopathologic spectrum,
diagnosis and pathogenesis. Int J Clin Exp Pathol 2008;1:396-402.
16. Clouston AD, Powell EE, Walsh MJ, Richardson MM, Demetris AJ, Jonsson JR. Fibrosis
correlates with a ductular reaction in hepatitis C: roles of impaired replication, progenitor
cells and steatosis. Hepatology 2005;41:809-818.
17. Brunt EM, Blomenkamp K, Ahmed M, Ali F, Marcus N, Teckman J. Hepatic progenitor
cell proliferation and liver injury in alpha-1-antitrypsin deficiency. J Pediatr Gastroenterol
Nutr 2010;51:626-630.
18. Richardson MM, Jonsson JR, Powell EE, Brunt EM, Neuschwander-Tetri BA, Bhathal
1
PS, et al. Progressive fibrosis in nonalcoholic steatohepatitis: association with altered
regeneration and a ductular reaction. Gastroenterology 2007;133:80-90.
19. Bioulac-Sage P, Cubel G, Balabaud C, Zucman-Rossi J. Revisiting the pathology of
resected benign hepatocellular nodules using new immunohistochemical markers. Semin
Liver Dis 2011;31:91-103.
20. Zhou H, Rogler LE, Teperman L, Morgan G, Rogler CE. Identification of hepatocytic and
bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in
cirrhotic human liver. Hepatology 2007;45:716-724.
21. Turner R, Lozoya O, Wang Y, Cardinale V, Gaudio E, Alpini G, et al. Human hepatic
stem cell and maturational liver lineage biology. Hepatology 2011;53:1035-1045.
22. Spee B, Carpino G, Schotanus BA, Katoonizadeh A, Vander Borght S, Gaudio E, et al.
Characterisation of the liver progenitor cell niche in liver diseases: potential involvement
of Wnt and Notch signalling. Gut 2010;59:247-257.
23. Van Den Heuvel MC, Slooff MJ, Visser L, Muller M, De Jong KP, Poppema S, et al.
Expression of anti-OV6 antibody and anti-N-CAM antibody along the biliary line of
normal and diseased human livers. Hepatology 2001;33:1387-1393.
24. Desmet VJ. Ductal plates in hepatic ductular reactions. Hypothesis and implications. I.
Types of ductular reaction reconsidered. Virchows Arch 2011;458:251-259.
25. Theise ND. Gastrointestinal stem cells. III. Emergent themes of liver stem cell biology:
niche, quiescence, self-renewal, and plasticity. Am J Physiol Gastrointest Liver Physiol
2006;290:G189-G193.
26. Wang Y, Yao HL, Cui CB, Wauthier E, Barbier C, Costello MJ, et al. Paracrine signals
from mesenchymal cell populations govern the expansion and differentiation of human
hepatic stem cells to adult liver fates. Hepatology 2010;52:1443-1454.
27. Lorenzini S, Bird TG, Boulter L, Bellamy C, Samuel K, Aucott R, et al. Characterisation
of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and
diseased human liver. Gut 2010;59:645-654.
28. Gouw AS, van den Heuvel MC, Boot M, Slooff MJ, Poppema S, de Jong KP. Dynamics
of the vascular profile of the finer branches of the biliary tree in normal and diseased
human livers. J Hepatol 2006;45:393-400.
29. Petersen B, Shupe T. Location is everything: the liver stem cell niche. Hepatology
2008;47:1810-1812.
30. Fellous TG, Islam S, Tadrous PJ, Elia G, Kocher HM, Bhattacharya S, et al. Locating the
stem cell niche and tracing hepatocyte lineages in human liver. Hepatology 2009;49:16552
1663.
31. Kuwahara R, Kofman AV, Landis CS, Swenson ES, Barendswaard E, Theise ND. The
hepatic stem cell niche: identification by label-retaining cell assay. Hepatology
2008;47:1994-2002.
32. Schmelzer E, Zhang L, Bruce A, Wauthier E, Ludlow J, Yao HL, et al. Human hepatic
stem cells from fetal and postnatal donors. J Exp Med 2007;204:1973-1987.
33. Haque S, Haruna Y, Saito K, Nalesnik MA, Atillasoy E, Thung SN, et al. Identification of
bipotential progenitor cells in human liver regeneration. Lab Invest 1996;75:699-705.
34. Oh SH, Witek RP, Bae SH, Zheng D, Jung Y, Piscaglia AC, et al. Bone marrow-derived
hepatic oval cells differentiate into hepatocytes in 2-acetylaminofluorene/partial
hepatectomy-induced liver regeneration. Gastroenterology 2007;132:1077-1087.
35. Theise ND, Nimmakayalu M, Gardner R, Illei PB, Morgan G, Teperman L, et al. Liver
from bone marrow in humans. Hepatology 2000;32:11-16.
36. Diaz R, Kim JW, Hui JJ, Li Z, Swain GP, Fong KS, et al. Evidence for the epithelial to
mesenchymal transition in biliary atresia fibrosis. Hum Pathol 2008;39:102-115.
37. Lunz JG, Specht S, Isse K, Clouston A, Demetris AJ. Ductular reactions during the
development of cirrhosis. In: De Morrow S, Marzioni M, Fava G, Glaser S, Alpini G,
editors. Pathophysiology of the Intrahepatic Biliary Epithelium. Kerala, India: Transworld
Research Network; 2008:223-256.
38. Jakubowski A, Ambrose C, Parr M, Lincecum JM, Wang MZ, Zheng TS, et al. TWEAK
induces liver progenitor cell proliferation. J Clin Invest 2005;115:2330-2340.
39. Viebahn CS, Benseler V, Holz LE, Elsegood CL, Vo M, Bertolino P, et al. Invading
macrophages play a major role in the liver progenitor cell response to chronic liver injury.
J Hepatol 2010;53:500-507.
40. Sicklick JK, Li YX, Melhem A, Schmelzer E, Zdanowicz M, Huang J, et al. Hedgehog
signaling maintains resident hepatic progenitors throughout life. Am J Physiol
Gastrointest Liver Physiol 2006;290:G859-G870.
41. Riehle KJ, Dan YY, Campbell JS, Fausto N. New concepts in liver regeneration. J
Gastroenterol Hepatol 2011;26(suppl 1):203-212.
42. Kotoula V, Hytiroglou P, Pyrpasopoulou A, Saxena R, Thung SN, Papadimitriou CS.
Expression of human telomerase reverse transcriptase in regenerative and precancerous
lesions of cirrhotic livers. Liver 2002;22:57-69.
43. Lunz JG 3rd, Tsuji H, Nozaki I, Murase N, Demetris AJ. An inhibitor of cyclin-dependent
kinase, stress-induced p21Waf-1/Cip-1, mediates hepatocyte mito-inhibition during the
3
evolution of cirrhosis. Hepatology 2005;41:1262-1271.
44. Menthena A, Koehler CI, Sandhu JS, Yovchev MI, Hurston E, Shafritz DA, et al. Activin
A, p15INK4b signaling, and cell competition promote stem/progenitor cell repopulation
of livers in aging rats. Gastroenterology 2011;140:1009-1020.
45. Furrer K, Rickenbacher A, Tian Y, Jochum W, Bittermann AG, Kach A, et al. Serotonin
reverts age-related capillarization and failure of regeneration in the liver through a VEGFdependent pathway. Proc Natl Acad Sci U S A 2011;108:2945-2950.
46. Delladetsima J, Alexandrou P, Giaslakiotis K, Psichogiou M, Hatzis G, Sypsa V, et al.
Hepatic progenitor cells in chronic hepatitis C: a phenomenon of older age and advanced
liver disease. Virchows Arch 2010;457:457-466.
47. Cassiman D, Libbrecht L, Sinelli N, Desmet V, Denef C, Roskams T. The vagal nerve
stimulates activation of the hepatic progenitor cell compartment via muscarinic
acetylcholine receptor type 3. Am J Pathol 2002;161:521-530.
48. Huang W, Ma K, Zhang J, Qatanani M, Cuvillier J, Liu J, et al. Nuclear receptordependent bile acid signaling is required for normal liver regeneration. Science
2006;312:233-236.
49. Apte U, Thompson MD, Cui S, Liu B, Cieply B, Monga SP. Wnt/beta-catenin signaling
mediates oval cell response in rodents. Hepatology 2008;47:288-295.
50. Tirnitz-Parker JE, Viebahn CS, Jakubowski A, Klopcic BR, Olynyk JK, Yeoh GC, et al.
Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor
cells. Hepatology 2010;52:291-302.
51. Sparks EE, Huppert KA, Brown MA, Washington MK, Huppert SS. Notch signaling
regulates formation of the three-dimensional architecture of intrahepatic bile ducts in
mice. Hepatology 2010;51:1391-1400.
52. Cowley AW Jr. The elusive field of systems biology. Physiol Genomics 2004;16:285-286.
53. Theise ND. Liver stem cells: the fall and rise of tissue biology. Hepatology 2003;38:804806.
54. Theise ND. Stem cell plasticity: recapping the decade, mapping the future. Exp Hematol
2010;38:529-539.
55. D'Inverno M, Theise ND, Prophet J. Mathematical modeling of stem cells: A complexity
primer for the stem cell biologist. In: Potten C, Wilson J, Clarke R, Renahan A, eds.
Tissue Stem Cells: Biology and Applications. 2nd ed. New York, NY: Marcel Dekker;
2006.
56. Theise ND. Now you see it, now you don't. Nature 2005;435:1165.
4
57. Theise ND. Implications of 'postmodern biology' for pathology: the cell doctrine. Lab
Invest 2006;86:335-344.
58. Hoehme S, Brulport M, Bauer A, Bedawy E, Schormann W, Hermes M, et al. Prediction
and validation of cell alignment along microvessels as order principle to restore tissue
architecture in liver regeneration. Proc Natl Acad Sci U S A 2010;107:10371-10376.
59. Roeder I. Quantitative stem cell biology: computational studies in the hematopoietic
system. Curr Opin Hematol 2006;13:222-228.
60. Rojkind M, Philips G, Diehl AM. Microarchitecture of the liver: a jigsaw puzzle. J
Hepatol 2011;54:187-188.
61. Odum EP, Barrett GW. Fundamentals of Ecology. 5th ed. Belmont, CA: Cengage
Learning; 2004.
62. Futuyma D. Evolutionary Biology. 3rd ed. Sunderland, MA: Sinauer Associates; 1998.
63. Powell EE, Jonsson JR, Clouston AD. Steatosis: co-factor in other liver diseases.
Hepatology 2005;42:5-13.
64. Clouston AD, Jonsson JR, Powell EE. Hepatic progenitor cell-mediated regeneration and
fibrosis: chicken or egg? Hepatology 2009;49:1424-1426.
65. Van Hul NK, Abarca-Quinones J, Sempoux C, Horsmans Y, Leclercq IA. Relation
between liver progenitor cell expansion and extracellular matrix deposition in a CDEinduced murine model of chronic liver injury. Hepatology 2009;49:1625-1635.
66. Svegliati-Baroni G, Faraci G, Fabris L, Saccomanno S, Cadamuro M, Pierantonelli I, et al.
Insulin resistance and necroinflammation drives ductular reaction and epithelialmesenchymal transition in chronic hepatitis C. Gut 2011;60:108-115.
67. Fabris L, Cadamuro M, Guido M, Spirli C, Fiorotto R, Colledan M, et al. Analysis of liver
repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch
signaling. Am J Pathol 2007;171:641-653.
68. Ryan MJ, Bales C, Nelson A, Gonzalez DM, Underkoffler L, Segalov M, et al. Bile duct
proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the
Alagille syndrome hepatic phenotype. Hepatology 2008;48:1989-1997.
69. Choi SS, Diehl AM. Epithelial-to-mesenchymal transitions in the liver. Hepatology
2009;50:2007-2013.
70. Wells RG. The epithelial-to-mesenchymal transition in liver fibrosis: here today, gone
tomorrow? Hepatology 2010;51:737-740.
71. Taura K, Miura K, Iwaisako K, Osterreicher CH, Kodama Y, Penz-Osterreicher M, et al.
Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice.
5
Hepatology 2010;51:1027-1036.
72. Rygiel KA, Robertson H, Marshall HL, Pekalski M, Zhao L, Booth TA, et al. Epithelialmesenchymal transition contributes to portal tract fibrogenesis during human chronic liver
disease. Lab Invest 2008;88:112-123.
73. Ziol M, Nault JC, Aout M, Barget N, Tepper M, Martin A, et al. Intermediate
hepatobiliary cells predict an increased risk of hepatocarcinogenesis in patients with
hepatitis C virus-related cirrhosis. Gastroenterology 2010;139:335-343 e2.
74. Yamashita T, Forgues M, Wang W, Kim JW, Ye Q, Jia H, et al. EpCAM and alphafetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma.
Cancer Res 2008;68:1451-1461.
75. Komuta M, Spee B, Vander Borght S, De Vos R, Verslype C, Aerts R, et al.
Clinicopathological study on cholangiolocellular carcinoma suggesting hepatic progenitor
cell origin. Hepatology 2008;47:1544-1556.
76. Lee JS, Heo J, Libbrecht L, Chu IS, Kaposi-Novak P, Calvisi DF, et al. A novel
prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor
cells. Nat Med 2006;12:410-416.
77. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646674.
78. Yamashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY, et al. EpCAM-positive
hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features.
Gastroenterology 2009;136:1012-1024.
79. Ikeda H, Sasaki M, Sato Y, Harada K, Zen Y, Mitsui T, et al. Bile ductular cell reaction
with senescent hepatocytes in chronic viral hepatitis is lost during hepatocarcinogenesis.
Pathol Int 2009;59:471-478.
80. Lennerz JK, Chapman WC, Brunt EM. Keratin 19 epithelial patterns in cirrhotic stroma
parallel hepatocarcinogenesis. Am J Pathol 2011;179:1015-1029.
6
Download