February 11, 2006
Comparative Biomedical Sciences Graduate Program
(1) Request to NCSU Graduate School for recognition of 5 concentration areas
(2) Action forms for new course “Fundamentals of comparative biomedical sciences”
_________________________________________________________________________
Ph. D. CONCENTRATIONS IN THE COMPARATIVE BIOMEDICAL SCIENCES PROGRAM
(1) CELL BIOLOGY
(2) INFECTIOUS DISEASES
(3) PHARMACOLOGY
(4) PATHOLOGY, AND
(5) POPULATION MEDICINE AND VETERINARY PUBLIC HEALTH
1. JUSTIFICATION. An estimate of the current and projected demand for graduates of the
proposed new degree program.
The CBS program, based at the College of Veterinary Medicine, is a multidisciplinary
college-based program (as opposed to department-based) in areas ranging from the
basic to applied and clinical biomedical sciences. Since its inception, students have had
the opportunity to select from one of five areas of specialization for their graduate
research: Cell Biology, Infectious Diseases, Pharmacology, Pathology, and Population
Medicine and Veterinary Public Health. Graduate faculty in the program (from CVM as
well as CALS and other institutions/agencies in the RTP) have also been aligned with
each of these five areas.
The program offers Master of Science (M.S.) and Doctor of Philosophy (Ph.D.)
degrees. This request is only for the Ph.D. degree; M.S. students, who represent a
minority of the graduate students in the CBS program (typically less than 5%), will
continue to receive the M.S. in Comparative Biomedical Sciences. For the most recent
Fall 2005 semester, 49 students were enrolled in the CBS program: 45 Ph.D. and 4 M.S.
students. The 45 Ph. D. students were aligned as 15 in Cell Biology, 6 in Infectious
Diseases, 2 in Pathology, 8 in Pharmacology and 14 in Population Medicine. This
student distribution in the different concentration areas has been relatively consistent for
the last few years and is expected to remain as such for the next few years.
Sample placement of 14 CBS post-graduates for 2004/05:
1.
2.
3.
4.
5.
6.
7.
8.
Nia Joyner Bullock, PhD with Brenda Alston-Mills - Cell Biology
Assistant Professor, NC A&T, Greensboro, NC
Gautam Sudhir Ghatnekar, PhD with Robert Anholt/David Malarkey - Cell Biology
Post-doc, Medical University of South Carolina, Charleston, SC
Andrea Karen Johnson, PhD with Jay Levine/Mac Law - Population Medicine
Research Assistant Professor, University of Maryland Eastern Shore, MD
Min Jung Kim, PhD with Greg Cole - Cell Biology
Postdoc, NICHD/NIH, Zebrafish/neural development
Reverie Alvarez Molina, PhD with Jay Levine - Population Medicine
Maternity break followed by postdoc
Faqir Muhammad, PhD with Jim Riviere – Pharmacology
Assistant Professor, Dept of Physiology/Pharmacology, University of
Agriculture, Faisalabad, Pakistan
Brian Chorley, PhD with Ken Adler – Cell Biology
Post doc, NIEHS
Siddartha Thakur, PhD with Wondwossen Gebreyes – Population Medicine
Post doc, FDA Maryland
9.
10.
11.
12.
13.
14.
Travis Knuckles, PhD with Ken Adler – Cell Biology
Post doc, Lovelace Pulmonary Research Center (pending), New Mexico
Kyle Landskroner, PhD with Neil Olson – Pharmacology
Staff scientist, Bayer (California)
Stanely Butch Kukanich, PhD with Mark Papich - Pharmacology
Assistant Professor, Kansas State University
Bin Jia, PhD with Fred Fuller – Cell Biology
Post doc, New England Primate Research Center, Boston
Christopher Houle, PhD with John Cullen - Pathology
Staff Pathologist, EPL Inc, N.C.
Karen Beck, PhD with Michael Stoskopf – Population Med
Staff Scientist, U.S. Fish and Wildlife Service, Southern Pines, NC
2. DESCRIPTION. Include how it differs from the existing concentration(s).
There currently are no university-recognized concentration areas within the CBS
program; students receive the same degree regardless of their research focus in cell
biology, infectious diseases, pathology, pharmacology or Population Medicine and
Veterinary Public Health. In several instances, CBS graduates have had to request
certification letters from the DGP or their advisors verifying that they had completed
their studies and research in a particular concentration area.
All students in the CBS program (regardless of concentration) are currently required
to take 1 course in biochemistry/cell biology/genetics or equivalent, 1 course in statistics,
1 course in research ethics, and seminar/journal club (Fall semester program-wide
research seminar). Given the interdisciplinary nature of the program and the current
need for any scientist in the biomedical sciences to be cognizant of fundamental
concepts and techniques across multiple disciplines, a new interdisciplinary overview
course will be required of all incoming graduate students; this will be in lieu of the 1
required course in biochemistry/cell biology/genetics or equivalent (Please see attached
course action forms for the new course).
In addition to course requirements for the CBS program, there will be course
requirements specific to each concentration area (see below).
3. OBJECTIVES. Describe the educational objectives of the concentration.
The objectives of the CBS graduate program are:
1. To train students to (1) conduct independent research in basic and/or applied
biomedical sciences in their area of specialization, (2) have a fundamental and
broad-based interdisciplinary knowledge of animal and human health related
biomedical sciences , and (3) develop critical thinking, oral and written
communication, and leadership plus team skills.
2. To prepare students for competitive careers at academic institutions, government
and non-profit agencies, or private industry.
3. To establish the CBS program as a premier comparative biomedical training program
at the national and international level including the training of veterinarians as
clinician-scientists.
Students in the CBS program will select and align their training with one of the five
concentration areas with an opportunity to individually tailor their focus in one or more
of these areas. The objectives of each concentration area are:
Cell biology
Graduate work in the Cell Biology Concentration Area seeks to provide state-of-theart research training in eukaryotic cell biology. This is accomplished via didactic courses,
journal clubs, and seminars that span a wide-range of topics including cell cycle control,
signal transduction, organelle function, differentiation, apoptosis, and molecular
oncology. Cell Biology students master a common set of course requirements and, with
input from their mentor and graduate committee, select a specialized set of courses that
are tailored to their individual research interests.
Infectious diseases
Graduate work in the Infectious Disease Concentration Area includes research at the
molecular and cellular level in bacteriology, parasitology, and virology, as well as
investigations of the host immune response to these agents. This is accomplished via
didactic courses, journal clubs, and seminars that span a wide-range of topics including
focus on etiology, pathogenesis, diagnostic development, vaccine development, and
antimicrobial therapies. Programs also focus on gene regulation and host-pathogen
interactions that influence pathogenesis. Research approaches employ a wide variety of
molecular, biochemical, pharmacological, and microscopic techniques, utilizing cell
culture and whole organisms.
Pathology
Graduate work in the Pathology Concentration Area includes research at the
molecular and cellular level in pathogenesis, oncology, toxicology, hematology,
infectious diseases and immunology. Research approaches employ a wide variety of
molecular, biochemical, pharmacological, and microscopic techniques, utilizing cell
culture and whole organisms. Graduate training in pathology is also accomplished via
didactic courses, journal clubs, and seminars that span the above areas of focus.
Pharmacology
Graduate work in the Pharmacology Concentration Area includes research at the
molecular and cellular level in pharmacology, pharmacokinetics, drug interactions, drug
residues and metabolites, anesthetics and autonomic drugs, pulmonary biology,
oncology, ophthalmology, gastroenterology, reproductive endocrinology, and lipid-,
peptide-, and oxygen-derived mediators of inflammation. Research approaches employ a
wide variety of molecular, biochemical, pharmacological, and microscopic techniques,
utilizing cell culture and whole organisms. Graduate training in pharmacology is also
accomplished via didactic courses, journal clubs, and seminars that span the above
areas of focus.
Population Medicine and Veterinary Public Health
Graduate work in the Population Medicine and Veterinary Public Health Concentration
Area includes research in epidemiology of a variety of species, medical geography,
assessment of management practices on food animal production systems, production
medicine for food industries, developing and monitoring systems for health and
productivity, computer based record keeping systems, and development of applied
statistical and analytic methods. Graduate training in Population Medicine and
Veterinary Public Health is also accomplished via didactic courses, journal clubs, and
seminars that span the above areas of focus.
4. ENROLLMENT HISTORY. Include the enrollment history for the current
program. Project the enrollment in the proposed concentration for four years and explain
the basis for the projections.
2002
2003
2004
2005
48
49
44
46
Ph.D.,
Ph.D.,
Ph.D.,
Ph.D.,
3
4
5
3
M.S.
M.S.
M.S.
M.S.
(breakdown by concentration area is not available)
(breakdown by concentration area is not available)
21 Cell Bio, 4 Inf Dz, 3 Path, 6 Pharm, 15 Pop Med
17 Cell Bio, 6 Inf Dz, 2 Path, 8 Pharm, 16 Pop Med
Projections:
With opening of the new CVM Research Building in May 2005 and recruitment of new
faculty with research intensive appointments, the CVM is projecting a 3-5% annual
increase in graduate students. Assumptions for the projections presented below are:
(1) Growth of CBS student intake will mimic the % projected for the college i.e. 4%
per year
(2) In line with the strategic plan of the university and CBS program focus on
doctoral training, we do not anticipate growth in number of M.S. students.
(3) Based on available numbers for 2003 and 2004, we predict a breakdown of 41%
Cell Biology, 10% infectious diseases, 5% pathology, 14% pharmacology, and 30%
Population Medicine and Veterinary Public Health.
`
2006
2007
2008
2009
49
51
53
55
Ph.D.,
Ph.D.,
Ph.D.,
Ph.D.,
2
2
2
2
M.S.
M.S.
M.S.
M.S.
21
22
23
23
Cell
Cell
Cell
Cell
Bio,
Bio,
Bio,
Bio,
5
5
5
6
Inf
Inf
Inf
Inf
Dz,
Dz,
Dz,
Dz,
2
3
3
3
Path,
Path,
Path,
Path,
7
7
7
8
Pharm,
Pharm,
Pharm,
Pharm,
16
17
18
18
Pop
Pop
Pop
Pop
Med
Med
Med
Med
5. OTHER PROGRAMS. Explain the relationship of the program to other programs
currently offered at NC State, including consultation with appropriate programs (as
necessary).
There is no overlap between the CBS program and proposed concentrations with
other programs offered at NC State. A copy of this document and the course action
form for the proposed new course have been sent to Dr. Ken Esbenshade, Associate
Dean for the College of Agriculture and Life Sciences.
6. CONCENTRATION REQUIREMENTS.
A minimum of 72 credit hours is required for the Ph.D. degree.
Total credits (minimum) required at the program level = 10 PLUS area requirement
Total credits (minimum) required for Cell Biology = 10
Total credits (minimum) required for Infectious Diseases = 6
Total credits (minimum) required for Pathology = 6
Total credits (minimum) required for Pharmacology = 15
Total credits (minimum) required for Population Medicine & Vet Public Health = 13
All students in the CBS program are required to take:
CBS 565 Fundamentals of Comparative Biomedical Sciences (new interdisciplinary,
overview course; 3 Credits; course action form attached)
ST 511 Experimental Statistics for Biological Sciences (3 Credits)
CBS 662 Responsible Conduct of Research (1 Credit)
CBS 800 Seminar series (1 Credit; every Fall semester with minimum 3 credits total)
*Additional course requirements for each concentration area are presented below.
Cell Biology Concentration (10 credits)
GN701 Molecular Genetics (3 credits)
CBS 770 Cell Biology (4 credits)
CBS 810C Seminar in Cell Biology (1 credit; every Spring semester with minimum 3
credits total)
Infectious Diseases Concentration (6 credits)
CBS 795I Special Topics in Infectious Diseases (3 Credits)
CBS 810B Seminar in Infectious Diseases (1 credit every Spring semester with
minimum 3 credit total)
Pathology Concentration (6 credits)
CBS 795A002 General Pathology (3 credits; waived for recent veterinary graduates
by approval)
CBS 810E Seminar in Pathology (1 credit every Spring semester with minimum 3
credits total)
Pharmacology Concentration (15 credits)
CBS 860 Instrumentation in Pharmacological Research (1 credit)
CBS 762 Principles in Pharmacology (3 credits)
CBS 787 Pharmacokinetics (3 credits)
CBS 785 Advanced Pharmacology (2 credits)
TOX 710 Biochemical Toxicology (3 credits)
CBS 810D Seminar in Pharmacology (1 credit every Spring semester with minimum
3 cr total)
Population Medicine and Veterinary Public Health Concentration (13 credits)
ST 512 Experimental statistics for biological sciences II (3 credits)
CBS 580 or UNC EPI 160 or UNC EPI 168 (3 credits)
CBS 580 Clinical Veterinary Epidemiology
EPI 160 Principles of Epidemiology
EPI 168 Fundamentals of Epidemiology
CBS 754 Principles of Analytical Epidemiology (3 credits)
CBS 810A Seminar in Population Medicine and Veterinary Public Health (1 credit
every Spring semester with minimum 3 cr total)
7. FACULTY. List faculty who will be directly involved in the proposed concentration and are
generally the same as for the existing degree program. If the faculty list is different, or if
new faculty are to be added, list them along with faculty rank, program, etc.
The faculty involved in each of the concentrations are from the current CBS program
faculty. A faculty member may participate in more than 1 concentration.
Cell Biology
Ken Adler, Jill Barnes, Anthony Blikslager, Matthew Breen, John Gadsby, Brian Gilger,
Jonathan Horowitz, Samuel Jones, Linda Martin, Nancy Monterio-Riviere, Jorge
Piedrahita, Marcelo Rodriguez-Puebla, Philip Sannes, Robert Smart, Don Thrall, and
Jeffrey Yoder.
Infectious Diseases
Craig Altier, Kevin Anderson, Prema Arasu, Ed Breitschwerdt, Gregg Dean, Fred
Fuller, Jody Gookin, Jim Guy, Bruce Hammerberg, Michael Levy, Ed Noga, Paul Orndorff
and Barbara Sherry.
Pathology
John Barnes, Talmage Brown, John Cullen, Marlene Hauck, Jerry McHugh Law and
Keith Linder
Pharmacology
Ronald Baynes, David Dorman, Lloyd Fleisher, Sarah Gardner, Christine McGahan,
Nancy Monterio-Riviere, Mark Papich, Doodipala Samba Reddy, Jim Riviere, and Robert
Smart.
Population Medicine and Veterinary Public Health
Kevin Anderson, Butch Baker, Maria Correa, Peter Cowen, Peter Farin, Wondwossen
Gebreyes, LeeAnn Jaykus, Suzanne Kennedy-Stoskopf, Jay Levine, David Ley, Robert
Sills, Barrett Slenning, Geof Smith and Michael Stoskopf.
8. BUDGET. Provide estimates of any additional costs required to implement the program
and identify the proposed sources of the additional required funds. This should include any
additional facilities, equipment, etc.
No additional funds are required since the program is already functioning within
context of the five concentration areas. New courses will be funded by the teaching budget
provided to courses in the CBS program by the CVM.
9. ADMINISTRATION. Describe how the proposed concentration will be administered.
This will generally be the same as the existing degree program. Outline the function of
each concentration leader and how they will interact with the DGP.
There will be no change in administration. The program and five areas are
currently administered by a Program Assistant (0.5FTE), DGP, and five concentration area
leaders. The five concentration area leaders will:
(1) mentor students
(2) organize concentration area faculty meetings at least once a year (for updates on
course requirements, concentration area specific activities, etc.)
(3) participate in meetings of the CBS Graduate Studies Committee (GSC), chaired
by the DGP
(4) serve as reviewers for applications to the program as well as to the specific
concentration area and in admission/stipend deliberations and selection by
the GSC
(5) coordinate the spring concentration-specific seminar series (CBS 810)
** Course action form and syllabus for new required CBS course is attached below.
NORTH CAROLINA STATE UNIVERSITY
GRADUATE COURSE ACTION FORM
NOTE: Click once on shaded fields to type data. To check boxes, right click at box, click “Properties”, and click “Checked” under
Default Values.
TYPE OF PROPOSAL
New Course
Drop Course
Course Revision
Dual-Level Course
REVISION
Content
Prefix/Number
Title
Abbreviated Title
Credit Hours
Contact Hours
Grading Method
Pre/Corequisites
Restrictive Statement
Description
Scheduling
DEPARTMENT/PROGRAM
Comparative Biomedical Sciences
COURSE PREFIX/NUMBER
CBS565
PREVIOUS PREFIX/NUMBER
NA
DATE OF LAST ACTION
NA
COURSE TITLE
Fundamentals of Comparative Biomedical Sciences
ABBREVIATED TITLE
18 LETTERS/SPACES ONLY
SCHEDULING
Fall
Spring
Alt. Year Odd
CREDIT HOURS
CONTACT HOURS
Studio
3
Summer
Alt. Year Even
Every Year
Other
OFFERED BY DISTANCE EDUCATION ONLY
Lecture/Recitation Seminar 3 Laboratory
Problem
Independent Study/Research
Internship/Practicum/Field Work
GRADING
ABCDF
INSTRUCTOR (NAME/RANK)
Jeffrey A. Yoder/Assistant Professor
Graduate Faculty Status Associate
ANTICIPATED
S/U
Full
PREREQUISITE(S)
Per semester
Max. per Section
Multiple sections Yes
15
15
Graduate or senior undergraduate standing
COREQUISITE(S)
NA
ENROLLMENT
No
PRE/COREQUISITE FOR
RESTRICTIVE STATEMENT
CURRICULA/MINORS
Required
Qualified Elective
Priority to graduate students; Enrollment of undergraduate students requires consent of
instructor
PROPOSED EFFECTIVE
August 2006
APPROVED EFFECTIVE DATE
__________________________
DATE
CATALOG DESCRIPTION: This course is designed for incoming graduate students and advanced undergraduates
interested in gaining a broad understanding of: comparative genomics, comparative immunology, comparative
physiology, pharmacokinetics, emerging zoonotic diseases, epidemiology and translational research models and
methods. This course also provides an overview of current technologies relevant to comparative biomedical
research and a foundation for implementing the scientific method (experimental design, data analyses, statistics).
DOCUMENTATION AS REQUIRED
Please number all document pages
Course Justification
Proposed Revision(s) with
Justification
Student Learning Objectives
RECOMMENDED BY:
_______________________________________________________________
________
Department Head/Director of Graduate Programs
Date
ENDORSED BY:
Enrollment for Last 5 Years
New Resources Statement
Consultation with other Departments
Syllabus (Old and New)
Explanation of differences in
requirements of dual-level courses
College Dean(s)
_______________________________________________________________
________
Chair, College Graduate Studies Committee
Date
_______________________________________________________________
_________
Date
APPROVED:
_______________________________________________________________________
Dean of the Graduate School
Course:
Fundamentals of Comparative Biomedical Sciences
Course Justification:
We are requesting a new CBS graduate-level course designed for 1st year graduate students. The CBS program is a
multi- and inter-disciplinary program spanning cell biology, infectious diseases, pathology, pharmacology, and
Population Medicine and Veterinary Public Health (including epidemiology and public health). Students entering the
program align with one of these five concentration areas but also have the ability for interdisciplinary training. This
course would provide an introductory overview of the fundamental concepts essential to any student in the biomedical
sciences as well as a variety of research strategies relevant to comparative medicine. Feedback from current CBS
graduate students indicated tremendous (>90%) support for a broad-based course that introduces the major
concepts , topics and methods relevant to comparative medicine that may be outside of their immediate research
interests.
This course will provide first year graduate students and advanced undergraduate students the opportunity to learn
about a variety of molecular techniques and biomedical approaches relevant to animal (including human) disease and
translational research using animal models. This course is designed to expose graduate students to a variety of
scientific enquiries and techniques that they may not receive in other advanced and specialized courses. It is also
designed to expose undergraduates to the scientific opportunities available at the graduate level. There is currently
no graduate level course at NC State University that covers these topics in a comprehensive manner.
Propose Revision(s) with Justification:
Not applicable.
Student Learning Objectives:
This course is designed to facilitate the students’ ability to gain a broad understanding of biomedical research and
molecular techniques. Through this course, students will gain:

a foundation of knowledge for advanced courses applicable to a graduate degree in Comparative
Biomedical Sciences (e.g. CBS 762/770/787/795I, GN 703, BCH 703, etc.),

information in comparative animal sciences (immunology, genomics, physiology, pharmacokinetics),

an understanding of infectious and emerging zoonotic diseases,

an understanding of the role of epidemiology and public health in comparative biomedical sciences.

an understanding of translational research models and methods,

an overview of current technologies (molecular, hardware, software, instrumentation) used in comparative
biomedical research,

an overview for the scientific method (experimental design, data analyses and statistics),
Enrollment for Last 5 Years:
Not applicable.
New Resources Statement:
Funds for the course will be allocated from the College of Veterinary Medicine teaching budget for courses in the
CBS program.
Consultation with other Departments:
The course syllabus and course action forms have been provided for review and comment to Dr. Ken Esbenshade,
CALS Associate Dean.
Syllabus (Old and New):
Old syllabus: not applicable.
New syllabus: see attached.
Explanation of differences in requirements of dual-level courses:
Not applicable.
Course Syllabus (DRAFT Jan 27 2006)
Comparative Biomedical Sciences
CBS5XX
Fall, 2006
Course Director: Jeffrey A Yoder, Ph.D.
Note: this syllabus is subject to change, particularly in the lecture topics. Students will be
notified in class of any changes.
Textbook: there is no required textbook for this course, but suggested reference materials
include
 Alberts et al., Molecular Biology of the cell, 4th Edition, ISBN = 081-8910687.
 Textbook #2
 Textbook #3
Handouts: Handouts will be provided as hardcopies in class or on-line as pdfs.
Class location: tba
Class time: Day 1 and Day 2 from X:XX to Z:ZZ (1.5 hrs each class).
Course Overview:
A. Goals. This is a 3 credit, graduate level course designed for incoming graduate students
and advanced undergraduate students interested in gaining a broad understanding of:
comparative genomics, comparative immunology, comparative physiology,
pharmacokinetics, emerging zoonotic diseases, the role of epidemiology and public
health in comparative biomedical sciences and translational research models and
methods. This course will also provide an overview of current technologies relevant to
comparative biomedical research and a foundation for implementing the scientific
method (experimental design, data analyses, statistics).
B. Class participation. There will be frequent in-class discussions of assigned readings
(including research or review articles). Your participation in these discussions and
discussion in general is worth 5% of your final grade.
C. Research Proposal. A written Research Proposal is worth 20% of your final grade. This
assignment can be considered a “mini-grant application”. Each student will submit a
written Research Proposal based on a topic relevant to the course and pre-approved by
at least one of the instructors and also made known to the course director. The
Research Proposal should be 1500-2500 words, cite current literature and include
figures and tables as needed. The paper will be read and graded independently by two
instructors. Incorrect spelling and punctuation can influence this grade.
FYI: The University policy on academic integrity can be found in the Code of Student
Conduct (found at http://www.fis.ncsu.edu/ncsulegal/41.03-codeof.htm). We expect
students to complete this assignment on an individual basis. In addition, plagiarism
(quoting authority as your own without referencing a citation or source) will not be
tolerated in the preparation of this assignment.
D. Exams. There will be 3 exams. Each exam is worth 25% of your final grade.
E. Grades: Students will be graded on :
a. Class participation: 5%
b. A paper on a selected topic: 20%
c. Three exams: 75%
F. Attendance: Class attendance is mandatory. If you miss a class for any reason, you are
responsible to get notes from another student. Students who anticipate the necessity of
being absent from class due to the observation of a major religious observance must
provide notice of the dates to the Course Director, in writing, by the second class
meeting.
G. Disabilities. Reasonable accommodations will be made for students with recognized
disabilities. Students with disabilities are invited to schedule an appointment (by the
second class meeting) with the course director to discuss appropriate accommodations.
In order to take advantage of available accommodations, students must register with
Disabilities Services for Students at 1900 Student Health Center, Campus Box 7509,
515-7653, http://www.ncsu.edu/provost/offices/affirm_action/dss/. For more information
about NC State’s policy on working with students with disabilities, please see:
http://www.ncsu.edu/provost/hat/current/appendix/appen_k.html.
H. Cell Phones: Please turn off all cell phones, beepers, pagers etc. during class.
I.
Participating Faculty: This course will be team taught by faculty in the CBS and related
Programs and include:
a.
b.
c.
d.
e.
f.
g.
h.
i.
j.
k.
Baynes, Ronald
Breen, Matthew
Breitschwerdt, Edward
Dean, Gregg
Deighton, Nigel
Gebreyes, Wondwossen
Law, Mac
Martin, Linda
Nascone-Yoder, Nanette
Reddy, Doodipala
Yoder, Jeff
513-6261
513-1467
513-8277
513-2819
513-0738
513-8291
515-7411
515-7393
513-7662
513-6549
515-7406
Ronald_Baynes@ncsu.edu
matthew_breen@ncsu.edu
ed_breitschwerdt@ncsu.edu
gregg_dean@ncsu.edu
ndeight@ncsu.edu
wagebrey@ncsu.edu
mac_law@ncsu.edu
linda_martin@ncsu.edu
Nanette_Nascone-Yoder@ncsu.edu
samba_reddy@ncsu.edu
Jeff_Yoder@ncsu.edu
Class
1
2
Day/Date
Subject
Reading
lecturer
Scientific method
Yoder
Experimental design, sample size,
Correa,
data evaluation and bias
(Gebreyes)
3
The animal cell
tba
4
DNA structure
Martin
5
Transcriptional control
Yoder
6
Translational control
Yoder
7
Protein structure and function
Yoder
8
Carbohydrates and lipids
tba
9
Genome organization;
Breen
Methodology for genome analyses
10
EXAM 1
-11
Comparative genomics
Breen/Yoder
12
Genotyping Methods
Gebreyes
13
Animal models for genetic disease
tba
14
Proteomics/Metabolomics
Deigton
15
Comparative physiology I
tba
16
Comparative physiology II
tba
17
Adaptive immunology
Yoder
18
Comparative immunology
Yoder
19
Infectious disease
Dean
20
EXAM 2
-21
Pathology: Cell Injury
Law
22
Pathology:
Law
Necropsy/Histopathology
23
Emerging zoonotic diseases
Breitschwerdt
24
Antimicrobial resistance
Gebreyes
25
Comparative Pharmacokinetics
Baynes
26
Molecular Pharmacology
Reddy
27
Pharmacogenetics, methodology
Nascone-Yoder
28
Tba (Methodology? i.e. other than
above; microscopy --?)
29
EXAM 3
-A written Research Proposal will be due XXXX XX, 2006. Details will be announced in class.