PUBLICATIONS: Diana Lopez, Ph. D.
SCIENTIFIC ARTICLES IN REFEREED JOURNALS
1.
2.
Lopez, D.M., M.M. Sigel, A.R. Beasley, and L.S. Dietrich. Biochemical and morphologic
studies of lymphocystis disease. Natl. Cancer Inst. Monograph 31:223-236 (1969).
Lopez, D.M., M.M. Sigel, and P. Meyers. Blastogenic transformation assay for detection
of immunologic reactivity to avian oncornaviruses. J. Natl. Cancer Inst. 51:303-305
(1973).
3.
Lopez, D.M., M.M. Sigel, and J.C. Lee. Phylogenetic studies on T cells. I. Lymphocytes
of the shark with differential response to phytohemagglutinin and Concanavalin A.
Cellular Immunol. 10:287-293 (1974).
4.
Lopez, D.M., M.M. Sigel, and P. Meyers. Lymphocyte response to mammary tumor
antigens free of mammary tumor virus in relation to clinical status. J. Natl. Cancer Inst.
52:289-292 (1974).
5.
Sigel, M.M., W. Lichter, and D.M. Lopez. In vitro methods to complement in vivo
approaches utilizing combinations of chemotherapy and immunotherapy. Cancer
Chemo. Rep. 4:109-114 (1974).
6.
Dorizzi, M., G. Ortiz-Muniz, D.M. Lopez, M.M. Sigel, and R.S. Epstein. Increase in the
proportion of cells with the C'3 receptor in BALB/c mice bearing mammary tumors. Int. J.
Cancer, 16:1015-1021 (1975).
7.
Lopez, D.M. and M.M. Sigel. Correlation of tumor growth and cell-mediated immune
responses of mice bearing mammary tumors following surgical procedures. J. Reticulo.
Soc., 18:305-312 (1975).
8.
Lichter, W., D.M. Lopez, L.L. Wellham and M.M. Sigel. Ecteinascidia turbinata extracts
inhibit DNA synthesis in lymphocytes after mitogenic stimulation by lectins. Proc. Soc.
Exptl. Biol. Med., 150:475-478 (1975).
9.
Sigel, M.M., D.M. Lopez, and G. Ortiz-Muniz. In vitro immune responses to viral and
tumor antigens in murine breast cancer. Cancer Res., 36:748-752 (1976).
10.
Lopez, D.M., G. Ortiz-Muniz, and M.M. Sigel. Macrophage migration inhibition and
lymphocyte stimulation with mammary tumor virus associated antigens in Balb/c mice.
Proc. Soc. Exptl. Biol. Med., 151:225-230 (1976).
11.
Sigel, M.M., D.M. Lopez, and G. Ortiz-Muniz. Migration inhibition and blastogenic
reactions with viral and tumor antigens in transplantable mammary tumor systems.
Annals N.Y. Acad. Sci., 276:358-368 (1976).
12.
Epstein, R.S., D.M. Lopez, G. Ortiz-Muniz, and M.M. Sigel. Emergence of a
subpopulation of lymphocytes bearing θ antigen and complement receptor during tumor
growth. Int. J. Cancer, 18:458-461 (1976).
13.
Lopez, D.M. and M.M. Sigel. Tumor antigen extracts stimulate cytotoxicity against
unrelated target cells. Int. J. Cancer 18:808-812 (1976).
14.
Lopez, D.M. and W. Voigt. Adenocarcinoma R-3327 of the Copenhagen rat as a suitable
model for immunological studies of prostate cancer. Cancer Res., 37:2057-2061 (1977).
15.
Lopez, D.M., M.M. Sigel, and L. Herbert. Enhanced killer cell activities induced by
progressive tumor growth. J. Reticulo. Soc., 22:437-443 (1977).
16.
Lopez, D.M., M.M. Sigel, G. Ortiz-Muniz, and W. Parks. Specificity and age of
appearance of natural immunity to MTV antigens. Proc. Soc. Exptl. Biol. Med., 158:2327 (1978).
17.
Sigel, M.M., J.C. Lee, E.C. McKinney, and D.M. Lopez. Cellular immunity in fish as
measured by lymphocyte stimulation. Marine Fisheries Rep, 40:6-11 (1978).
18.
Epstein, R.S., D.M. Lopez, and M.M. Sigel. Divergent appearance of complement
receptors and Fc receptors on T cells in a murine mammary tumor system. Cell.
Immunol., 40:154-163 (1978).
19.
Distasio, J.A., D.M. Lopcz, A. Ghaffar, M.M. Sigel, and M.A. Silverman. Mechanism of
specifically induced non-specifically expressed cytotoxicity. J. Reticulo. Soc., 24:161-167
(1978).
20.
Epstein, R.S., D.M. Lopez, M.M. Sigel and G.D. Ross. Characteristics of complement
receptor-bearing cells in the spleens of tumor-bearing mice. J. Immunol., 121:1524-1527
(1978).
21.
Voigt, W. and D.M. Lopez. Characterization of prostate carcinoma lines in the
Copenhagen rat. Natl. Canccr Inst. Monogr. 49:269-273 (1978).
22.
Lozzio, B.B., D.M. Lopez, P. Coulson, and S.V. Lair. High incidence of mammary tumors
in mice with inherited asplenia carriers for thc nude gene. Cancer Res., 39:1529-1533
(1979).
23.
Charyulu, V., M.M. Sigel, D.L. Durden and D.M. Lopez. Mouse mammary tumor virus
(MMTV) antigen(s) are present on B lymphocytes of BALB/c mice. Int. J. Cancer 24:385393 (1979).
24.
Lopez, D.M., M.M. Sigel, and V.L. Charyulu. Kinetics of responses to tumor antigens and
mouse mammary tumor virus in BALB/cCrgl and BALB/cfC3H mice. J. Natl. Cancer
Inst., 66:191-196 (1981).
25.
Lopez, D.M., V. Charyulu, and M.M. Sigel. Subset of spleen lymphocytes from
BALB/cCrgl mice stimulated by mouse mammary tumor virus. Cancer Res., 41:813-818
(1981).
26.
Paul, R.D., A. Ghaffar, M.M. Sigel, V. Charyulu, and D.M. Lopez. Splenic alterations
during mammary tumorigenesis: Diverse effects on different immune parameters.
Anticancer Research 1:63-69 (1981).
27.
Lopez, D.M., W.P. Parks, M.A. Silverman, and J.A. Distasio. Lymphoproliferative
responses to mouse mammary tumor virus in lymphocyte subsets of breast cancer
patients. J. Natl. Cancer Inst., 67:353-358 (1981).
28.
Distasio, J.A., D.A. Cheresh, R.J. Schilder, C.L. Vogel, M.A. Silverman, and D.M. Lopez.
Maximizing differences in the Concanavalin A-induced blastogenic responses of
lymphocytes from breast cancer patients and controls by the use of α-methyl-Dmannoside. J. Natl. Cancer Inst., 68:69-74 (1982).
29.
Lopez, D.M., M.M. Sigel, and J. Schlom. Detection of type specific antigenic
determinants of murine mammary tumor viruses with cell mediated immune assays.
Proc. Soc. Exptl. Biol. Med., 169:144-148 (1982).
30.
Cheresh, D.S., J.A. Distasio, C.L. Vogel, and D.M. Lopez. Mitogen-induced
blastogenesis and receptor mobility inhibition by breast cancer serum with elevated
orosomucoid (α1-acid glycoprotein) levels. J. Natl. Cancer Inst., 68:779-783 (1982).
31.
Buessow, S.C., K. Caldwell, M.A. Fletcher, and D.M. Lopez. Purified membrane
fractions from mammary tumor cells elicit biological reactivity in in vitro cell-mediated
immune reactions. Eur. J. Cancer Clin. Oncol., 18:595-604 (1982).
32.
Lopez, D.M., R.D. Paul, A.U. Gadgil, and W. Lichter. Functionally sensitive and resistant
populations of lymphoid cells from normal and mammary tumor bearing mice following
treatment with cyclophosphamide. Anticancer Res., 2:227-234 (1982).
33.
Lopez, D.M. and R.D. Paul. Analysis of lymphoid cells responding to virus- and tumorassociated antigens in spleens of syngeneic mouse mammary tumor systems with low
and high oncogenic potentials. J. Natl. Cancer Inst., 69:1403-1410 (1982).
34.
Lopez, P.F., W.P. Parks, and D.M. Lopez. Antigenic determinants in a virus-induced
mouse mammary tumor recognized by cell-mediated immune assays. J. Natl. Cancer
Inst., 72:725-732 (1984).
35.
Buessow, S.C., R.D. Paul, A.M. Miller and D.M. Lopez. Lymphoreticular cells isolated by
centrifugal elutriation from a mammary adenocarcinoma. I. Characterization of an in situ
lymphocyte suppressor population by surface markers and functional reactivity. Int. J.
Cancer, 33:79-85 (1984).
36.
Paul, R.D., R. Padmanabhan, and D.M. Lopez. Characterization of the effector cells
mediating an "innocent bystander" cytotoxicity reaction induced by a syngeneic
mammary adenocarcinoma in mice. Cancer Res., 44:4480-4486 (1984).
37.
Buessow, S.C., R.D. Paul, and D.M. Lopez. Influence of mammary tumor progression on
phenotype and function of spleen and in situ lymphocytes in mice. J. Natl. Cancer Inst.,
73:249-255 (1984).
38.
Lopez, D.M. Humoral and cellular immune responses to mouse mammary tumor virus
(MMTV) in experimental animal models. Anticancer Res., 4:305-312 (1984).
39.
Balazovich, K.J., D.M. Lopez, and L.Y.W. Bourguignon. The involvement of the
cytoskeleton during antibody-depedent cellular cytotoxicity (ADCC). Cell Biology Int.
Reports 8:923-938 (1984).
40.
Lopez, D.M., V. Charyulu, and R.D. Paul. B Cell Subsets in Spleens of Balb/c Mice:
Identification and isolation of MMTV-expressing and MMTV-responding subpopulations.
J. Immunol., 134:603-607 (1985).
41.
Lopez, D.M., R.J. Pauley, and B.B. Lozzio. Interaction of heterozygous nude gene with
the asplenia trait in mammary tumorigenesis. J. Exp. Med., 161:629-634 (1985).
42.
Lopez, D.M., P.F. Lopez, W.P. Parks, and R.D. Paul. Dependence of initiation of an
innocent bystander cytotoxicity reaction on the association of viral antigens and tumor
cell membranes in mice. J. Natl. Cancer Inst., 76:923-931 (1986).
43.
Paul, R.D. and D.M. Lopez.
Induction of Ainnocent bystander@ cytotoxicity in
nonimmune mice by adoptive transfer of L3T4+ Lyt 1+,2+ mammary tumor immune Tcells. Cancer Res. 47:1105-1110 (1987).
44.
Padmanabhan, R.R., R.D. Paul, G.A. Watson, and D.M. Lopez. Emergence of a B
lymphocyte population with ADCC effector function in mammary tumor bearing mice. J.
Leuk. Biol. 43:509-519 (1988).
45.
Lopez, D.M., B.B. Blomberg, R.R. Padmanabhan, and L.Y.W. Bourguignon. Nuclear
disintegration of target cells by killer B lymphocytes from tumor bearing mice. FASEB
Journal 3:37-43 (1989).
46.
Fu, Y-X., N. Altman, and D.M. Lopez. Thymic atrophy induced by murine mammary
adenocarcinoma in vivo. In Vivo 3:1-6 (1989).
47.
Fu, Y-X., R.D. Paul, Y. Wang, and D.M. Lopez. Thymic involution and thymocyte
phenotypic alterations induced by murine mammary adenocarcinomas. J. Immunol.
143:4300-4307 (1989).
48.
Fu, Y-X., G. Watson, J.J. Jimenez, Y. Wang, and D.M. Lopez. Expansion of
immunoregulatory macrophages by granulocyte-macrophage colony-stimulating factor
derived from a murine mammary tumor. Cancer Res. 50:227-234 (1990).
49.
Watson, G.A., Y-X. Fu, and D.M. Lopez. Splenic macrophages from tumor bearing mice
co-expressing MAC-1 and MAC-2 antigens exert immunoregulatory functions via two
distinct mechanisms. J. Leuk. Biol. 49:126-138 (1991).
50.
Pauley, R.J. and D.M. Lopez. Expression of endogenous Mtv provirus transcripts in
BALB/c splenic lymphocytes. Proc. Soc. Ex. Biol. Med. 196:316-320 (1991).
51.
Lopez, D.M., M. Lopez-Cepero, G.A. Watson, A. Ganju, E. Sotomayor, and Fu Y-X.
Modulation of the immune system by mammary tumor-derived factors. Cancer Invest.
9:643-653 (1991).
52.
Fu, Y-X., G.A. Watson, M. Kasahara, and D.M. Lopez. The role of tumor-derived
cytokines on the immune system of mice bearing a mammary adenocarcinoma. I.
Induction of regulatory macrophages in normal mice by the in vivo administration of
rGM-CSF. J. Immunol. 146:783-789 (1991).
53.
Sotomayor, E.M., Y-X. Fu, M. Lopez-Cepero, L. Herbert, J.J. Jimenez, C. Albarracin,
and D.M. Lopez. Role of tumor derived cytokines on the immune system of mice bearing
a mammary adenocarcinoma. II. Down-regulation of macrophage-mediated cytotoxicity
by tumor derived granulocyte-macrophage colony stimulating factor. J. Immunol.
147:2816-2823 (1991).
54.
Fu, Y-X., J.P. Cai, Y.H. Chin, G.A. Watson, and D.M. Lopez. Regulation of leukocyte
binding to endothelial tissues by tumor-derived GM-CSF. Int. J. Cancer 50:585-588
(1992).
55.
Lopez, D.M. Modifications of antitumor defenses by tumor derived factors and by
superantigens. Medicina (B.A.) 52:539-548 (1992).
56.
Sotomayor, E.M., K. Rao, D.M. Lopez, and A. Liepins. Enhancement of macrophage
tumoricidal activity by the alkaloid derivative Ukrain. In vitro and in vivo studies. Drugs
Exptl. Clin. Res. 18:5-11 (1992).
57.
Rivera, L.M. and D.M. Lopez. NK cells from mammary tumor bearing mice do not exert
natural killer activity but function as antibody dependent cellular cytotoxicity effectors.
Anticancer Research 13:177-184 (1993).
58.
Sotomayor, E.M., X.F. Cheng, Y-X. Fu, A. Hawkins, C. Calderon-Higginson, and D.M.
Lopez. Impaired activation of tumoricidal function in macrophages from mammary tumor
bearers: The role of IFN-γ. International J. Oncology, 3:719-727 (1993).
59.
Dewanjee, M.K., A.K. Ghafouripour, M. Kapadvanjwala, E.L. Oates, A. Krishan, D.M.
Lopez, A.N. Serafini, and G.N. Sfakianakis. Radiolabel antisense oligodeoxynucleotides:
In vitro and in vivo applications. J. Clin. Immunoassays 16:276-289 (1993).
60.
Lopez-Cepero, M., J.A. Garcia-Sanz, L. Herbert, R. Riley, M.E. Handel, E.R. Podack,
and D.M. Lopez. Soluble and membrane bound TNF-α are involved in the cytotoxic
activity of B cells from tumor bearing mice against tumor targets. J. Immunol. 152:33333341 (1994).
61.
Dewanjee, M.K., A.K. Ghafouripour, M. Kapadvanjwala, S. Dewanjee, A.N. Serafini,
D.M. Lopez, and G.N. Sfakianakis. Noninvasive imaging of c-myc oncogene messenger
RNA with indium-111-antisense probes in a mammary tumor-bearing mouse model. J.
Nuclear Med. 35:1054-1063 (1994).
62.
Calderón, C., Z-H. Huang, D.A. Gage, E.M. Sotomayor, and D.M. Lopez. Isolation of a
nitric oxide inhibitor from mammary tumor cells and its characterization as phosphatidyl
serine. J. Exp. Med., 180:945-958 (1994).
63.
Sotomayor, E.M., M.R. DiNapoli, C. Calderon, A. Colsky, Y-X. Fu, and D.M. Lopez.
Decreased macrophage- mediated cytotoxicity in mammary-tumor-bearing mice is
related to alteration of nitric oxide production and/or release. Int. J. Cancer, 60:660-667
(1995).
64.
Lopez-Cepero, M., Y. Wang, I. Keydar, C. Brandt-Carlson, J.S. Butel, and D.M. Lopez.
Detection of retroviral superantigen and products of the envelope gene from
endogenous mouse mammary tumor virus in B cells from BALB/c mice. Cellular
Immunology, 163:191-197 (1995).
65.
Watson, G.A. and D.M. Lopez. Aberrant antigen presentation by macrophages from
tumor bearing mice is involved in the down-regulation of their T cell responses. J.
Immunol., 155:3124-3134 (1995).
66.
Xie, Y., M.E. Handel, J.W. Streilein, and D.M. Lopez. Epidermal Langerhans cells from
mice bearing a granulocyte-colony stimulating factor-producing mammary tumor display
impaired accessory functions. Anticancer Research, 16:9-16 (1996).
67.
DiNapoli, M.R., C. Calderon, and D.M. Lopez. The altered tumoricidal capacity of
macrophages isolated from tumor-bearing mice is related to reduced expression of the
inducible nitric oxide synthase gene. J. Exp. Med., 183:1323-1329 (1996).
68.
Lopez, D.M., M.E. Handel-Fernandez, X. Cheng, V. Charyulu, L.M. Herbert, M.R.
DiNapoli, and C.L. Calderon. Cytokine production by lymphoreticular cells from
mammary tumor bearing mice: the role of tumor-derived factors. Anticancer Research,
16:3923-3930 (1996).
69.
Handel-Fernandez, M.E., X. Cheng, L.M. Herbert, and D.M. Lopez. Downregulation of
IL-12, not a shift from a T helper-1 to T helper-2 phenotype, is responsible for impaired
IFN-γ production in tumor bearing mice. J. Immunol. 158:280-286 (1997).
70.
DiNapoli, M.R., C.L. Calderon, and D.M. Lopez. Phosphatidyl serine is involved in the
reduced rate of transcription of the inducible nitric oxide synthase gene in macrophages
from tumor bearing mice. J. Immunology, 158:1810-1817 (1997).
71.
Handel-Fernandez, M.E., and D.M. Lopez. Altered binding of the NF-GMa transcription
factor is involved in the upregulated production of TNF-α by macrophages of mammary
tumor bearing mice. Int J. Mol. Med. 1:227-234 (1998).
72.
Cheng, X-F., and D.M. Lopez. CD4+ but not CD8+ T cells from mammary tumor bearing
mice have a downregulated production of IFN-γ: Role of phosphatidyl serine. J.
Immunol, 160:2735-2741 (1998).
73.
Charyulu, V.I., and D.M. Lopez. Abnormal binding pattern and composition of the NF-κB
complex components are involved in increased TNF-α production by tumor bearers= B
cells. Int. J. Mol. Med., 3:411-416 (1999).
74.
Charyulu, V., and D.M. Lopez. Elevated GM-CSF levels in tumor bearing mice
upregulates IL-6 production by B cells via a mechanism independent of TNF-α. Int. J.
Oncology, 16:161-167 (2000).
75.
Adkins, B., Q.-L. Sun, V. Charyulu, D. Lobo, and D.M. Lopez. Early block in maturation
Is associated with thymic involution in mammary tumor bearing mice. J. Immunol.
164:5635-5640 (2000).
76.
Sun, Q.-.L., V. Charyulu, D. Lobo, and D.M. Lopez. Role of thymic stromal cell
dysfunction in the thymic involution of mammary tumor bearing mice. Anticancer
Research 22:91-96 (2002).
77.
Lopez, D.M., V. Charyulu, and B. Adkins. Influence of breast cancer on thymic function
in mice. J. Mammary Gland Biology and Neoplasia 7:191-199 (2002).
78.
Torroella-Kouri, M., J.C. Keith, M. Ivanova, and D.M. Lopez. IL-11 induced reduction of
c/EBP transcription factor binding may contribute to the IL-12 downregulation in tumorbearing mice. Int. J. Oncol. 22:439-448 (2003).
79.
Owen, J., V. Iragavarapu-Charyulu, Z. Gunja-Smith, L.M. Herbert, J.F. Grosso, and D.M.
Lopez. Upregulation of matrix metalloproteinase 9 in T lymphocytes of mammary tumor
bearers: Role of vascular endothelial growth factor. J. Immunol. 171:4340-4351 (2003).
80.
Torroella-Kouri, M., and D.M. Lopez. Mammary tumor derived TGF-β1 impairs crucial
innate immune response in tumor hosts. J. Immunol. and Immunopathol. 5:31-38 (2003).
81.
Grosso, J.F., L.M. Herbert, J.L. Owen, and D.M. Lopez. MUC1/sec-expressing tumors
are rejected in vivo by a T cell-dependent mechanism and secrete high levels of CCL2.
J. Immunol. 173:1721-1730 (2004).
82.
Herbert, L.M., J.F. Grosso, M. Dorsey Jr., I. Keydar, G. Kraus, M. Cejas, D. Wreschner,
and D.M. Lopez. A unique mucin immunoenhancing peptide with antitumor properties.
Cancer Research 64:8077-8084 (2004).
83.
Torroella-Kouri M, Herbert LM, Perry G and Lopez DM. Altered IL-12 Signaling
Pathways Contribute to the Deficient IFN-γ
ion by T Splenocytes from Tumor
Bearing Mice, Cancer Genomics and Proteomics 1:345-354. (2004)
84.
DiNapoli M.R., Torroella-Kouri M., Perry G., and Lopez D.M. Diminished PKC activity
and decreased binding of transcription factors are involved in the impaired production of
nitric oxide by macrophages from tumor-bearing mice. Int J Molecular Med 15:503-11
(2005).
85.
Torroella-Kouri M, Ma X, Perry G, Ivanova M, Cejas PJ and Lopez DM. Altered NFκB
and C/EBP signaling pathways underline dysregulation of cytokine and their receptor
gene expression in macrophages of mammary tumor-bearing mice, submitted to Cancer
Research 65: 10578-10584. (2005)
86.
Owen, J.L., D.M. Lopez, Grosso, J.F., Guthrie, K-M., Herbert, L.M., Torroella-Kouri, M.,
and and Iragavarapu-Charyulu, V. The expression of CCL2 by T lymphocytes of
mammary tumor bearers: role of tumor-derived factors. Cellular Immunology 235 -122135. (2005)
BOOK CHAPTERS AND SYMPOSIA CONTRIBUTIONS
1.
Sigel, M.M., D.M. Lopez, A.R. Beasley, and L.S. Dietrich. Virus-cell interaction in
lymphocystis disease of fish. In Viruses Affecting Man and Animals, Ed. M. Sanders.
Warren H. Green, Inc., St. Louis, pp. 124-135 (1971).
2.
Sigel, M.M., P. Meyers, H.T. Holden and D.M. Lopez. Humoral and cellular immunity in
Rous sarcoma In Virus Tumorigenesis and Immunogenesis, Eds. W.S. Ceglowski and
H. Friedman. Academic Press, pp. 289-320 (1973).
3.
Sigel, M.M., G. Ortiz-Muniz, J.C. Lee, and D.M. Lopez. Immunobiological reactivities at
the cellular level in the nurse shark. In Colloques de Institut National de la Sante et de la
Recherche Medicale - Paris. pp. 113-119 (1973).
4.
Lichter, W., M.M. Sigel, D.M. Lopez, and L.L. Wellham. Inhibition of DNA Synthesis by
Ecteinascidia turbinata extracts (ETE). 1974 Food-Drugs from the Sea Proceedings,
Eds. H.H. Webber and G.D. Ruggieri, pp. 395-401, Marine Technology Society (1976).
5.
Sigel, M.M., W. Lichter, L.L. Wellham, and D.M. Lopez. Cytotoxic and antiproliferative
substances in invertebrates and poikilothermic vertebrates. Proc. In Invertebrate Tissue
Culture, Eds. E. Kurstak and K. Maramorosch, Academic Press, Inc., N.Y., pp. 309-314
(1976).
6.
McKinney, E.C., G. Ortiz-Muniz, J.C. Lee, M.M. Sigel, D.M. Lopez, R.S. Epstein, and
T.F. McLeod. Lymphocytes of fish: Multipotential or specialized? In Phylogeny of
Thymus and Bone Marrow-Bursa Cells .Eds. R.K. Wright and E.L. Cooper,
Elsevier/North Holland Biomedical Press, Amsterdam, pp. 73-82 (1976).
7.
McKinney, E.C., C.L. Pettey, D.M. Lopez, and M.M. Sigel. Cytotoxicity of nurse shark
(Ginglymostoma cirratum) leukocytes. In Developmental Immunobiology, Eds. J.B.
Solomon and J.D. Horton, Elsevier/North Holland Biomedical Press, Amsterdam, pp.
217-224 (1977).
8.
Lopez, D.M., M.M. Sigel, V. Charyulu, G. Ortiz-Muniz, J. Schlom, and B. Lozzio. Cellmediated immunity to MMTV antigen(s): its relevance to host defenses against
mammary tumors. In Breast Cancer: New Concepts in Etiology and Control. Eds. M.J.
Brennan, C.M. McGrath, and M.S. Rich. Academic Press, Inc., N.Y., pp. 387-406, 1980.
9.
Lopez, D.M., R. Paul, L. Herbert, L. Wellham, and W. Lichter. Selective effects of
cyclophosphamide on different parameters of the immune response. In Current
Chemotherapy and Infectious Disease, Eds. J.D. Nelson and C. Grassi. American
Society for Microbiology Publications, Washington, D.C., pp. 1726-1728 (1980).
10.
Buessow, S., D.M. Lopez and A.M. Miller. The use of diffusion chambers in the study of
tumor immunobiology and lymphokines. In Diffusion Chamber, Springer-Verlag, Berlin
Heidelberg, New York, pp. 234-241 (1980).
11.
Lopez, D.M., R.J. Pauley and R.D. Paul. Mammary tumor virus infections and immunity.
In Viruses, Immunity and Immunodeficiency, Eds. A. Szentivanyi and H. Friedman.
Plenum Press, pp. 109-122 (1986).
12.
Lopez, D.M. New developments in breast cancer immunology. Dev. Oncol. 43:112-130
(1986).
13.
Pauley, RJ. and D.M. Lopez. Mammary tumor virus RNA expression in splenic B
lymphocytes from MMTV-negative Balb/c mice. In ICSU Short Reports. Eds. David Puett
et al, Cambridge University Press, New York, Vol. 4, pp. 138-139 (1986).
14.
Lopez, D.M. Immunologic monitoring and immunotherapeutic reagents: new approaches
to the management of breast cancer. In Proceedings of the Breast Diseases IVth
International Congress on Senology, Paris, France, Imprimerie Louis-Jean, Ed. J. Gest,
pp. 195-201 (1986).
15.
Lopez, D.M., R.R. Padmanabhan, L.M. Rivera, R.D. Paul, L. Herbert, C. Cray, and G.A.
Watson. Cytotoxic effector mechanisms involved in the immunity against mammary
tumors. In Breast Cancer: Scientific and Clinical Progress. Eds. M.A. Rich, J.C. Hager
and D.M. Lopez. Kluwer Acad. Publ., Boston, pp. 185-205 (1988).
16.
Rivera, L.M., R. Hamelik, J.F. Wood, and D.M. Lopez. Expansion in tumor-bearing mice
of a NK population with high levels of ADCC and increased expression of Fc receptors.
In Natural Killer Cells and Host Defense. Eds. E.W. Ades and C. Lopez. S. Karger
Publishers, Basel pp. 262-269 (1989).
17.
Lopez, D.M., R.D. Paul, and R.J. Pauley. Phenotypic expression of endogenous
retroviral antigens in B lymphocytes. In Cellular Basis of Immune Modulation. Eds. J.G.
Kaplan and D.R. Green. Alan R. Liss Inc., New York pp.491-494 (1989).
18.
Rivera, L. and D.M. Lopez. NK cells from tumor-bearing mice are effective at post
binding events critical for efficient secretion of granule-associated factors. In Natural
Killer Cells: Biology and Clinical Application, Ed. R.E. Schmidt. S. Kargen Publishers,
Basel pp. 139-145 (1990).
19.
Lopez-Cepero, M., Y. Wang, R. Riley, and D.M. Lopez. Expression of mouse mammary
tumor virus antigen(s) on pre-B cells of Balb/c mice. In: Lymphatic Tissues and In vivo
Immune Response. Eds. B.A. Imhof, S. Berrih-Aknin, and S. Ezine, Marcel Dekker, Inc.
New York, pp. 385-389 (1991).
20.
Lopez, D.M., D. Cideciyan, K. Rao, and Y.H. Chin. Lymphocyte homing in mammary
neoplasia. In Lymphatic Tissues and In vivo Immune Response. (B.A. Imhof, S. BerrihAknin, S. Ezine. Marcell Dekker, Inc. New York, pp. 947-951 (1991).
21.
Lopez, D.M.
Immunosuppression from breast tumor derived factors and its
consequences for the cancer patient. In: Proc. First Int. Congress Hell. Soc. Breast
Cancer Res. (N.J. Agnantis, ed) pp. 87-89 (1993).
22.
Dewanjee, M.K., J. Glick, M. Abrams, A.K. Ghafouripour, M. Khuddus, M.
Kapadvanjwala, S. Dewanjee, A. Koppolu, W. Lichter, A.N. Serafini, S. Ezuddin, W.
Ganz, W. Mallin, A.G. Krishan, D.M. Lopez, and G.N. Sfakianakis. Labelling
oligonucleotide specific for targeting messenger-RNA of amplified oncogene (C-MYC)
with Tc-99m and noninvasive imaging of breast tumor in mouse model. In Chemistry and
Nuclear Medicine (M. Nicolini, G. Bandoli, U. Mazzi, eds), pp. 577-580 (1995).
23.
Lopez, D.M. Recent advances on immunology of breast cancer. Proc. HSBCR Second
International Congress (N.J. Agnantis, ed), pp. 96-99 (1995).
24.
Lopez, D.M., Cheng, X., and Handel-Fernandez, M.E. Interferon γ-downregulation in
mammary tumor bearing hosts: Implications for Tumor Progression and Immunotherapy.
In Proceedings of the 22nd Congress of the International Association for Breast Cancer
Research (Ioannidou-Mouzaka, L., Agnantis, N.J., and Lopez, D.M. eds), Monduzzi
Editore, Bologna, Italy, pp. 11-15 (1999).
25.
Handel-Fernandez, M.E. and Lopez, D.M. Isolation of macrophages from tissues, fluids,
and immune response sites. In: Macrophage Methodology: A practical approach (D.M.
Paulnock, ed) Oxford University Press, Oxford. Chapter 1, pp. 1-30 (2000).
26.
Lopez, D.M. Alterations of macrophage functions during mammary tumor development.
In: Mechanisms of Tumor Escape from Immune Recognition (A. Ochoa, ed) Harwood
Academic Publishers GMBH, Switzerland, Chapter 7, pp. 142-160 (2002).
27.
Owen, J.L., V. Iragavarapu-Charyulu, and D.M. Lopez. T cell-derived matrix
metalloproteinase-9 in breast cancer: friend or foe? In: Breast Disease. IOS Press,
Amsterdam, the Netherlands 20:145-153 (2004).
EDITED BOOKS
1.
2.
3.
4.
5.
Puett, D., F. Ahmad, S. Black, D.M. Lopez, M.H. Melner, W.A. Scott and W.J. Whelan
(eds). Advances in Gene Technology: Molecular Biology of thc Endocrine System, ICSU
Short Reports, Vol. 4, Cambridge University Press, New York, 402 pp. (1986).
Rich, M.A., J.C. Hager, and D.M. Lopez (eds). Breast Cancer Scientific and Clinical
Progress. Kluwa Acad. Publ., Boston (1988).
Streilein, J.W., F. Ahmad, H. Bialy, S. Black, B. Blomberg, Y.H. Chin, D.M. Lopez, T.
Malek, E.R. Podack, M.B. Rabin, J. Stein-Streilein, J. Van Brunt, and W.J. Whelan (eds).
Advances in Gene Technology: The Molecular Biology of Immune Diseases and the
Immune Response. ICSU Short Reports, Vol. 10, Oxford Press, (1990).
Ioannidou-Mouzaka, L., Agnantis, N.J., and Lopez, D.M. (eds). Proceedings of the 22nd
Congress of the International Association for Breast Cancer Research. Monduzzi
Editore, Bologna, Italy, (1999).
Wei, W.Z. and Lopez, D.M. (eds). Immunology of Breast Cancer, Breast Disease. IOS
Press, Amsterdam, the Netherlands (2004).
BOOK REVIEWS
1.
Lopez, D.M. (Reviewer) The Human Oncogenic Viruses: Molecular Analysis and
Diagnosis. (eds. Luderer, A.A. and Weetall, H.H.) FASEB J. 2: (1988).