KLE UIVERSITY’S Dr. Prabhakar Kore Basic Science Research Center [BSRC], Belagavi. Record of Major Activities held at BSRC during the Month of May-2015 Sr. No. Particulars Status Dr. NehaDhaded 1. Antimicrobial efficiency of ozone, photo activated disinfection & Ongoing conventional irrigation with 3% sodium hypochlorite during root [Short-Study] canal treatment an In Vivo comparative study. Dr. Vanashree 2. Evaluation of biofilm on fixed functional appliance “Twin Block” Ongoing [Dissertation] Dr. Harshita Mishra 3. Comparison of effectiveness of Zanthoxylumnitidum Extract Ongoing &Chlorehexidine mouth rinse on salivary streptococcus mutans, [Dissertation] plaque & gingival scores among 12-15 year old children in Belgaum city-a randomized controlled field trial. Dr. VidhiKevadia 4. A clinical & microbiological study to evaluate the efficacy of Ongoing locally delivered benzyl isothiocyanate as an adjunct to scaling & [Dissertation- Pilot root planning in chronic periodontitis. Study] Dr. Mahesh Kamate[Clinical Collaborator] 5. Consultant Paediatric Neurologist, KLE Hospital, Belgaum. Ongoing Research Project entitled “ Screening of ATP7 B Gene Mutations in Indian Patients with Wilson Diseases” Dr. Triveni Mohan Nalawade Ex-vivo evaluation of the antimicrobial activity of various 6. Ongoing combinations of intracanal medicaments and vehicles on selected pathogens from deciduous molars with necrotic pulp. Mr. Bhanwase Anil Subhash 7. Cytotoxic activity of plant extract. Ongoing 8. Mrs. Shruti Kulkarni Ongoing Anticancer Potential of unifloral honey samples from Western Ghats of India on selected Cell Lines-An invitro study. Mr. Avinash A K Math 9. Ongoing Molecular Characterization and Anticancer Potential of Antibacterial Peptides Isolated from Royal Jelly. Dr. AmbikaDhiman 10. Ongoing Preparation of cauliflower acetone extract by rotavapour procedure. 11. Ms. Shubhangi D. Jabade Ongoing Cell lines pertaining to Skin Cancer. Mr. Vivek Kulkarni 12. ‘Phenotypic and Molecular Characterization of Methicillin Resistant Staphylococcus aureus from Clinical Samples and Ongoing Hospital Environment of North Karnataka’. Mr. M. G. Hogade 13. Evaluating the antimicrobial & antibacterial activity & Ongoing biochemical parameters of the given sample. 14. Mr. Amit kumarMaisale ‘Investigate activities on Antibacterial and antifungal’. Ongoing Dr. ShilpaGunjal ‘Comparison of effectiveness of Morus alba and 15. chlorehexidine gels on moderate periodontitis among 35 to 55 Ongoing year old subjects- A hospital based randomized controlled trial’. Mr. MukundMarutiGade 16. ‘Formulation and development of antiobese agents from natural origin’. 17. Dr. Madhav Prabhu Conduct of biochemical tests Initiated Initiated Mr. M. Vinyas 18. ‘Pharmacological Evaluation of Agents Altering Insulin Initiated Metabolism In Experimentally Induced Diabetes in Rats’. 19. Ms. Archana S. Patil ‘Standard Calibration Curve of Oraliplatin by HPLC’ Initiated Dr. NirajGodbole 20. ‘Determination of minimum instrumentation size using Initiated protaper file system’. Dr. Ramya R.M 21. ‘Estimation and Correlation of Human rat vary Greffoct Ongoing Factor 3 levels in Health and chrome percodonhtin’. Dr. SingbalReshaUday ‘Evaluation and comparison of anti-Candida effect, surface 22. porosities and flexural strength of heart cure polymethylmethacrylate resin enforced with silver Ongoing nanoparticles and conventional heat cure resins: An in vitro study’ Dr. Supriya S. Vyarahare 23. ‘Comparison of two caries risk assessment tools in deaf Ongoing &deembAchol children in Belgaum City.’ 24. Mrs. Netra R. Hiremath, ARAR Short study on Immuno Modulatory Activity. Ongoing Ms. SummyKumari 25. “Formulation &evaluation of Polymeric Nanoparticles of Initiated Acycloner for Ocular delivery. Ms. TanujaBisht 26. “Comparative Preparation and Evaluation of methods of Initiated Preparation of Candesartan cilexetil nanoparticles”. Mr. RavindraDashrathBendgude 27. “Synthesis Anticancer AMD Anti TB studies of Completed Disubstituted-1H-Imidazole Derivatives”. Mr. P. Karunakar 28. ‘Prepare and evaluate transdermal patches using ethanolic Ongoing vesicle carries loaded with Linagliptin and Capsaicin’. Ms. DipikaSawant 29. “Formulation and evaluation of thermosensitive In- Initiated Situemulsomal Gel of Sparfloxacin”. Dr. Niyati S. Balse 30. “Evaluation of wound healing and bone regeneration using autologous platelet rich plasma and platelet rich fibrin post Initiated extractions-A comparative study”. Dr. Prabhanjan V. Mulasavalgi “To evaluate effect of Alfa-Tocoferol, Zinc and Combination 31. of Alfa Tocoferol-Zinc on periodontal Ligment Fibroblast Cell proliferation, Migration and Differentiation: An in Vitro Ongoing study”. 32. Ms. Annie Pereira Initiated Ms. Laxmi Pattanashetti 33. ‘Neuroprotectective effect of Quercetine with Donepezil on Initiated Scopolarune induced amnesia in rats’. 34. 35. Mr. T. Madhusudhan HPLC analysis Initiated Mr. Gururaja K. Anti cancer studies by using plant extracts. Initiated Ms. GuttaSrividhya 36. ‘Estamation of Antibacterial Activity-Methanol Extract of Initiated TinosporaCordifolia’. Dr. Manisha Singh 37. ‘Prevalence of Various Oral Candidal Species in Pateints with Initiated Oral Mucosal Lesions’. Dr. ManjulaVagarali 38. Molecular Characterisation of Helicobacter pylori in Acid Ongoing Peptic Disease. 39. Mr. Narendra Kulkarni Biosynthesis of Nanoparticles and their Food Application. Ongoing Mr. Sreyash S. Kalangutkar 40. “Formulation and evaluation of Linagliptin loaded Ongoing ultradeformable vesicles for improved transdermal delivery.” Dr. Santosh Y. Nelogi 41. Proliferation, Differentiation and matrix mineralization of osteoblast like cell on titanium disc by C.Quadrangularis. An Initiated in vitro study 42. Dr. DipikaBangera “Estimation of salivary Interleukin-10 levels in healthy Initiated individuals and patients with recurrent minor aphthous ulcers in active phase and remission phase.-A prospective study.” Mr. Vivek Prakash Kadam 43. Mr. Babar Chandrashekhar V. Ongoing Dr.PoojaWalia 44. “To evaluate the effect of photodynamic therapy as an adjunct to scaling and root planning in Patients with chronic Ongoing periodontitis – A Randomised controlled clinical trial. Mr. Kunal Ganesh Raut. Mr. Vikrant VijaykumarNawale 45. “Development of Antitubercular Agents Using Pharmacophore Optimization By Molecular Modeling Ongoing Studies”. Mrs. GeetPawankumarAsnani 46. 47. “Formulation and Evaluation of Colan targeted drug delivery system using natural polysaccharides”. Ongoing Veena N. Chavan Ongoing Kirandeep Kaur 48. Evaluation of Osseo Induction by Chitosan Coated Iron Ongoing Nanoparticles Dr. Vaibhav Kumar 49. Assessing the anticancer activity of vacciniummacrocarpon extract and its antimicrobial action on predominant pathogens Ongoing of the oral cavity – An In- Vitro Analysis. 50. Mrs. Gouri Krishna Vhanamani Biodiesel from non-edible oil plants Ongoing Dr. Neelamma A Shetti 51. Prevalence of Chronic Periodontitis in Dyspeptic Patients and Determining the Association Between Gastric H Pylori Ongoing Infection and Periodontal Disease. 52. Mr. Mahendra Kumar Chouhan Ongoing 53. Mr. KummaraSivaiah Ongoing STUDENT PROJECTS COMPLETED Sr. No. Particulars Miss. MeghaRokhade; Miss. Sharon Noronha; Mr. UdayHeddurshetti 1 2 Synthesis of TiO2 Nanoparticle and their evaluation for anti-acne and anti-cancer activity Gourav Soni, M. Pharma Student [Dissertation to be Submitted] Study of current guidelines policies &evalution of selected biological products Dr. PareshLotlekar; MD Student [Dissertation to be Submitted] 3 Detection & quantitative estimation of aggregatibacteractinomycetemcomitans levels in periodontal healthy adults & chronic periodontitis patients by polymerase chain reaction: a cross sectional study. 4 Ms. Hyma Formulation and evaluation of fast dissolving tablets and films of Lornoxicam. Dr. Neha Saini, MD Student [Dissertation to be Submitted] 5 Comparative evaluation of the antifungal efficiency of resin based, MTA based &bioceramic based sealer against Candida albicans. Dr. RohiniSarnaik, MD Student [Dissertation to be Submitted] 6 To assess the correlation between serum cotinine levels and Bone mineral density among male tobacco users Dr. AkankshaTiwari, MD Student [Dissertation to be Submitted] Assessment of bacterial contamination in mobile communication devices among dental 7 practitioners in Belgaum city – a cross sectional study. [Received First Best Oral Paper Presentation award at 16th Scientific Convention, 16/17th August 2013] Dr. ShikhaRastogi; Dr. AnubhaRathi, MD Student [Dissertation to be Submitted] 8 Submitted research project entitled “Assessment of microbial contamination of as received and clinic exposed orthodontic materials: an in vitro microbiology investigation” Dr. PreetiMaste, MD Student [Dissertation to be Submitted] 9 Research Project entitled “Detection and Confirmation of Brucellosis by Polymerase Chain Reaction” Dr. SheetalKubasad 10 Determination of antibacterial effectiveness of root canal irrigants against selected single species biofilm by direct contact test-an in vitro study. Ms. AkshataBadiger 11 Project work related Water quality & Environmental microbiology. Dr. LadusinghRajpurohit 12 Evaluation of the antimicrobial activity on various concentration of wheat grass (Tritium aestivum) extract against gram positive & gram negative bacteria: An in vitro study. Ms. Mugdha Joshi 13 ‘Formulation and evaluation of Cefuroxime Axetil sol gel for periodontitis’. Dr. SachinJavali 14 Experimental evaluation of Hypoglycemic effect of Aragwadha [Cassia Fistula Linn.] in streptozotocin induced diabetic rats Dr. Rayanna. Naikar 15 Experimental evaluation of Atisaraghna [anti diarrhoeal] effect of Lodhra [SymplocosRacemosaRoxb.] Dr. Anand B. Khannaikar 16 Experimental evaluation of Shothahara [anti-inflammatory] karma of Gokshura [TribilusTerristerisLinn.] Ms. EshaPaikar 17 Formulation & Evaluation of misoprostol sublingual tablets Mr. AnilkumarChinchole 18 Method development & validation of anticancer drug formulation by using HPLC &invitroanticancer on selected cell lines. Ms.SharadaKamshette 19 Method development & validation of antipsychotic drug formulation by using HPLC. Mrs.DeeparaniUralogin 20 To perform the antimicrobial activity of selected plant extract. Ms. Liza Pyngrope 21 Ms. ShifaKakkar In-vitro cytotoxicity of test samples. Ms. NibhaPhalgaonkar 22 To assist in microbiological studies on devised formulations. Ms. Mugdha Joshi 23 Formulation and Evaluation of Cefuroxime axetil sol gel for periodontitis Ms. AkshataBadiger 24 Project work related Water quality & Environmental microbiology Dr. Smita Kore 25 Effect of various concentrations of platelet rich plasma on periodontal ligament fibroblast cell migration, proliferation & differentiations: an In Vitro study. 26 Mr. TammannaBajantri ‘Antimicribial activity of antibiotics against Aeromonashydrophila’ Dr. Malini Shankar 27 Comparative evaluation of the antifungal properties of MTA, CEM &Biodentine cement by modified direct contact test –an invitro study. Ms. Ashwini 28 Project work related Water quality & Environmental microbiology Ms. SupriyaKapali 29 Project work related Water quality & Environmental microbiology. Dr. RoopaliSankeshwari 30 ‘Effectiveness of Licorice varish, Fluoride varnish and Combination of Both, on Incipient Lesions of Early Childhood Caries in 4 year old preschool children of Belgaum city-A randomized controlled trial.’ Dr. Shavina S. Patil 31 ‘Photon induced photo acoustic streaming in disinfection of root canals-an in vitro study’. Mr. B. M. Dinnimath 32 ‘Method Development and validation of Quercetin’. Mr. S. Abhay 33 ‘Antimicrobial activity of selective extract’. Mr. SatishAlate 34 Mr. Amol Jadhav Ms. Archana Rajmane Preparation of Niosome formulations. Dr. Nikhil Jambagi 35 Antimicrobial efficiency of a diode laser, ultrasonic activated & conventional irrigation with 2.5% sodium hypo chloride during root canal treatment, an In vivo comparative study. Dr. Amrita Rathore 36 “Evaluation of P Gingiovalisand F Nucleatum and periodontal status in mothers with low birth weight and normal birth weight” Miss Anifa Xavier 37 Use of Rotavapour for experimental work Mr. Amit Patel 38 39 40 Using HPLC. Ms. BhaghyalaxmiGondhali Using HPLC. Ms. Asmita Singh Using HPLC. Mr. Prince Agarwal 41 ‘Stress induced charges in insulin and thyroid level in seriously ill patient in intensive care unit and their influence in final outcome’. Dr. SagarJogur 42 Detection and assessment of human herpes viruses [EBV, HCMV, HSV-1 and HSV-2] in varying pocket depths in generalized aggressive periodontitis patients. Dr. HarshaGopeAssudani 43 “Comparative evaluation of the Antibacterial activity of type II GIC, type IX GIC and Amalgomer CR bymodified direct contract test”-An in vitro study. Dr. VishwajitRampratapChaurasia 44 MIC of samples Mr.AmolkumarKempawade 45 Formulation & evaluation of flexible liposome enriched In-situ thermo reversible intranasal gel of Rizatriptan benzoate. Dr. Sneha Patil 46 Comparative evaluation of cytotoxicity of herbal irrigants on cultured human periodontal ligament fibroblasts. Mr. Aadit R. Pandhya 47 ‘Method development and validation of Lafutidine and Rabeprazole sodium in bulk and dosage form on UPLC’. Ms. DipikshaSawant 48 49 Use of ultrasonicator and Rotary evaporator for dissertation work Mr. S.V. Vijay Kumar ‘Formation and evaluation of Tizanidine Nanoparticles’. Dr. MadhurimaHazra 50 Effect of α- tocopherol& selenium on periodontal ligament fibroblast proliferation & migration. Dr. SphurtiUpadhaya 51 ‘Pharmaceutico analytical study of Vajragomutra Yoga and its cell line anti-tumor activity’. Mr. NitinAmbhore 52 HPLC analysis of drug samples. Dr. Sreeshma P 53 Molecular typing of Pseudomonas aeroginosa by RAPD Mr. Ravindra D Hiremath [Reg. No. DOUN12018] Mr. Shriram R. Pethakar [Reg. No. DOUN12017] 54 Ms. T. Uraih [Reg. No. DOUN12020] Research activities for Ph.D. Dissertation work Mr. Prashant R. Chavan 55 Cytotoxicity studies were done on DAL cells by tryphan blue exclusion method. Ms. CharuPundir 56 ‘Screening of Quinolone derivatives as possible anticancer agent in Dalton’s ascites lymphoma in mice’. Dr. RuchikaGarg 57 ‘To assess and compare the level of Total Human Survivin Salivary Biomarker in leukoplakia, lichen planus and oral cancer-A Comparative Study’. Dr. RohiniPurohit 58 “Pharmacokinetics of Madhutailikabastiw.s.r. absorption-an exploratory study”. Ms. Poorvi Kulkarni, 59 Ms. MahalaxmiHumbarwadi, Mr. Sabir Khan Testing of antimicrobial activity using different combinations of essential oils. Ms. ShivikaMathur 60 ‘Method development and validation of Linaglitin by UPLC’. Mr. Dinesh Dhamecha 61 ‘Syntheses of gold nanoparticles and its applications’. Mr. KummaraSivaiah 62 ‘Comparative Toxicity Profiling of Silver Nanoparticles from Prepared Synthetic and Green Methods’. Mr. Royden Rodrigues 63 Analytical Method development and validation of Dicyclomine Hydrochlorides and Diclofenac Sodium in Pharmaceutical Dosage Form by UPLC. Dr. Wali 64 DNA isolation from blood sample (Qiagen kit) Mr. TanaviHegadi 65 Ms. Tanisha Nesarikar “Testing of antimicrobial activity”. Mr. Akshay S. Bhope 66 Ms. Alisha Shiledar “Testing of antimicrobial activity”. Ms. NehaAinapure 67 Mr. Jayanth C.S. “Testing of antimicrobial activity”. Ms. VaidehiDhopavkar 68 “Qualitative Evaluation of Apically Extruded Debris and Instrumentation Time using Protaper Next, K3Xf and Hyflex Rotary Systems-An In Vitro Study. Dr. Neha Arora 69 “Effect of Glide path preparation on Apical Debris Extrusion of ProTaper Next”. Dr. Manisha Singh 70 Prevalence of Various Oral Candidal Species in Pateints with Oral Mucosal Lesions Ms. PoojaMangavati. Ms. Maria Rochelle Rego 71 Optimization and comparision of Banana peel extract with TinosporaCordifoliafor antioxidant activity Ms. Ch.SahithiPrabha 72 “To analyse the antimicrobial effect of plauntrex gel against E.faecalis in human root dentin by comparing with most commonly used medicaments.” Dr. Sweta V. Sagare 73 An in vitro evaluation of Ocimum sanctum and morindacitrifolia as a potential storage media to maintain cell viability for avulsed teeth using collagenase- Dispase assay. Dr. PriyaSapra 74 ‘Evaluation of the antimicrobial efficacy of Calcium Hydroxide with Imipenem,Calcium Hydroxide with OctenidineDihydrochloride and Calcium Hydroxide against Enterococcus faecalis. 75 Dr. SupriyaShetye ‘Biological Interactions of Recasted Alloys and Its Influence on Oral Tissues’. Dr. Rakesh Sharma 76 Evalution of effectiveness of satranidazole chitosan inserts as an adjunct to non-surgical therapy in chronic periodontitis- A clinical and microbiological study. Mr. Iranna 77 Patient. Ms. Anju 78 Patient.