Club de Vaccinologie 2015 meeting Programme 21st-23rd of January 2015, Institut Pasteur - Paris 14-14h15 Welcome address C. Brechot, I. Pasteur 14h15-15h OPENING LECTURE Chair : Armelle Phalipon & Behazine Combadiere “Vaccines, new opportunities for a new society” R. Rappuoli, Novartis, Italy SESSION BASIC IMMUNOLOGY - JANUARY 21ST, 2015 AFTERNOON Chairs: Eric Tartour & Anne Hosmalin 15h Molecular and cellular strategies of development and diversification of B lymphocyte subsets 15h30 Boundaries of a Healthy Immune Response to Complex Stimuli. 16h00 Engineering immunity with “hitchhiking” vaccines C.-A. Reynaud, France M. Albert , France D. Irvine, USA coffee break 16h30-17h15 17h15 Human Antibody Response to HIV-1 17h45 BCG-induced trained innate immunity in monocytes and NK-cells; vaccination studies, experimental models and epigenetics 18h15 short talks 3-4 (10min/talk) H. Mouquet, France R. van Crevel, Netherlands social hour and poster session 19h-20h SESSION CUTTING EDGE - JANUARY 22ND, 2015 MORNING Chairs: Isabelle Schwartz & Claude Leclerc 9H 9h30 10h How transcriptomic study helps finding new concept for dengue vaccine development Tailoring vaccines by a profound knowledge of pathogenesis and immunity in veterinary medicine Targeting the Mutanome for Individualized Cancer Immunotherapy coffee break 10h30-11h15 11h15 skin vaccination by omics analysis 11h45 Hyper-parametric analysis of immune cells: the CYTOF approach 12h15 Prix Jacques Oudin (SFI, LSB) : Jérome Galon 12h30 short talks (10min/talk) Lunch 13h-14h30 1 A. Sakuntabhai, France H. Nauwynck, Belgium U. Sahin, Germany B. Combadière, France A. Cossarizza, Italy CLINICAL TRIALS - JANUARY 22ND, 2015 AFTERNOON Chairs: Odile Launay & Philippe Moigeon 14h30 Dynamical modeling in immunology and vaccination 15h Development of new vaccines against Enteric Fever 15h30 Phase III : Capita R. Thiebaut, France A. Podda, Novartis, Italy Heinz-J. SCHMITT, Pfizer, EU coffee break 16h-16h45 16h45 Dengue Vaccine: an update 17h15 Cancer immunotherapy - from off-the-shelf to actively personalized 17h45 The virtuous circle of preclinical model , clinical research, human trials.... and back 18h00 short talks 3 B. Guy, Sanofi-Pasteur, France S.Walter, Germany N. Garcon, Bioaster, France (10min/talk) social hour and poster session 18h45-19h30 Diner (invited speakers) FUTURE CHALLENGES - JANUARY 23RD, 2015 MORNING Chairs: Bertrand Dubois & Brigitte Autran 9H 9h30 10h Interplay between gut microbiota and APC: impact for vaccination strategies? Human immune memory of Staphylococcus aureus – insights for vaccine development Vaccines for elderly M. Rescigno, Italy B.M. Bröker, Germany B. Weinberger, Austria coffee break 10h30-11h15 11h15 The non-specific effects of live and inactivated vaccines P. Aaby, Denmark KEYNOTE LECTURE - JANUARY 23RD, 2015 Chair: Behazine Combadiere & Armelle Phalipon 11h45-12h45 Rafi Ahmed, Emory Vaccine Center, USA “On CD8 T Cell Memory” Closing and Award ceremony Anne Hosmalin ORGANIZING COMMITTEE: B. COMBADIÈRE & A. PHALIPON Scientific Committee : B. Autran, B. Combadière, B. Dubois, M. Girard, A Hosmalin, G. Inschaupé, G. 2 Kroemer, O. Launay, C. Leclerc, C. Locht , P. Moingeon, A. Phalipon, I. Schwartz, E. Tartour