City College of San Francisco Biology Seminar Series Fall 2010 Seminars are held at the Ocean campus and are co-sponsored by the City College Concert and Lecture Series. The lectures are free and open to the public. Seating is limited. For this reason we recommend contacting the seminar organizers listed below to check on seating. Confessions of a Cuttlefish Breeder. Speaker: Richard Ross, Aquatic Biologist, Steinhart Aquarium California Academy of Sciences Date: Friday, September 10th Location: S300 Time: Noon-1 p.m. Synopsis: Cuttlefish are one of the most amazing cephalopods. Related to their more famous cousins octopus, squid and clams (really, clams), cuttlefish maneuver around like hummingbirds, vertically, horizontally, their fins appearing blurred like wings. As they fly about they flash amazing color changes, creating patterns that pulse and shift and shimmer on the canvas of their skin. They are master predators, stalking their prey with cunning and attacking with accuracy, speed, camouflage and skill. I am fortunate to see this wonder of evolution every day at the CAS. This talk will include discussion of cuttle physiology, behavior and husbandry as well as some details of the CAS cuttle breeding efforts (including some exciting new breakthroughs) through photos and video. I will also discuss how and why I am in involved with these animals, and my not so traditional career path. 1 Some Observations on Immunizations for VaccinePreventable Diseases: Speaker: Clark D. Hinderleider, M.D., Ph.D. Treasurer, Marin Immunization Coalition Chair, Health Care Legislation and Comparative Effectiveness Research Task Force; Health Council of Marin. Member, Advocacy Committee; California Immunization Coalition Date: Friday, September 17th Location: S300 Time: Noon-1 p.m. Synopsis: Dr Hinderleider shall speak about the need for immunizations for Vaccine Preventable Diseases (VPD) and the concept of herd immunity. The talk will include discussion of the pertussis outbreak in Marin and the rise of “personal-belief exemptions” for vaccines. The history of the antivaccine movement will be addressed, including the Wakefield story, the "celebrity" and public story, the vast amount of misinformation, the science denialists, and the special masters' ruling. The talk will cover some of the more common myths regarding vaccines and their safety such as autism, preservatives and thimerosal. The Owls of California Speaker: Craig Nikitas; is an urban planner who has a life-long fascination with birds including a particular interest in raptors, or birds of prey. He has been an animal care volunteer at the Randall Museum, working with captive hawks, owls and ravens, and at Steinhart Aquarium, He has banded birds of prey with the Golden Gate Raptor Observatory. He has lectured about hawks, owls, and corvids at many venues in an around San Francisco. Date: Friday, October 15th Location: S300 Time: Noon-1 p.m. 2 Synopsis: We will discuss the natural history of owls, including amazing adaptations which enable them to be silent, effective, and frequently nocturnal hunters. An overview of 16 species, with a particular focus on eight whose range includes the Bay Area, plus one recent invader, will be provided. The presentation will examine where these birds live, what they eat, how to identify them, and what they sound like. Deep Water Horizon Oil Spill - Intrinsic Bioremediaiton or Mother Natures's Abilities to Cleanup Our Messes. Speaker, Terry C. Hazen, Ph. D. DOE BER Distinguished, Scientist Head, Ecology Department.Head, Center for Environmental Biotechnology, Director, Microbial Communities, Joint BioEnergy Institute, Co-Director, Virtual Institute Microbial Stress and Survival,Earth Sciences Division, UC Lawrence Berkeley National Laboratory Date: Friday October 22nd Location: S300 Time: Noon-1 p.m. Synopsis: The biological effects and expected fate of the vast amount of oil in the Gulf of Mexico from the Deepwater Horizon blowout are unknown due to the extreme depth and magnitude of this event, but also the unprecedented quantity of oil dispersant released and injected directly at the wellhead (1,544 m). We found that the dispersed hydrocarbon plume stimulated deep-sea indigenous bacteria that are closely related to known petroleum-degraders. Hydrocarbondegrading genes coincided with the concentration of various oil contaminants. Changes in hydrocarbon composition with distance from the source, environmental isolates, and microcosms demonstrate faster then expected hydrocarbon biodegradation rates even at 5°C. This explains why intrinsic bioremediation of the oil plume in the deep-water column without substantial oxygen 3 drawdown occurred after only 2-3 weeks of capping the leak. Antibodies: An important new class of therapeutics; From discovery to development Speaker: James D. Marks, M.D., Ph.D. Professor of Anesthesia and Pharmaceutical Chemistry. Chief of Anesthesia, San Francisco General Hospital, Vice Chairman, Dept. of Anesthesia and Perioperative Care UCSF. Date: Friday, October 29th Location: S300 Time: Noon-1 p.m. Synopsis: Antibody-based therapeutics currently enjoy unprecedented success, growth in research and revenues, and recognition of their therapeutic potential. There are currently more than 20 monoclonal antibodies (mAbs) approved by the United States Food and Drug Administration (FDA) for clinical use and many more are in clinical trials for treatment of various diseases including cancers, immune disorders and infections. These therapeutic successes reflect the major advances in antibody engineering which have resulted in the generation of safe, specific, high affinity, and non-immunogenic antibodies during the last three decades. In this seminar we will review how mAbs became an important therapeutic class, the developments in antibody engineering that made this possible, and speculate on where the antibody therapeutic field is heading. Information about the seminars is available at: http://www.ccsf.edu/Departments/Biology Contact the seminar coordinators: Carole Toebe, PhD Biology Department, CCSF Tel: 415-239-3475 email: ctoebe@ccsf.edu 4 Stephanie Lyons Coordinator: CCSF Concert Lecture Series Tel: 415-239-3580 email: slyons@ccsf.edu 5