B81402 – HISTOLOGY and EMBRYOLOGY 1,2 B81134 – Oral Histology and Embryology week LECTURES Teacher: Ass. Prof. MUDr. Jirsová PRACTICAL LESSON 2. Nervous system. Brain cortex, cerebellum, and spinal cord. Structure and function of the skin Sensory epithelium – structure and function. Sensory organs 3. Introduction to embryology. Fertilization, cleavage and blastocyst formation. Implantation of the blastocyst;. Ectopic pregnancy 4. Development of the yolk sac, amnion, chorion, and embryonic disc 5. Formation of germ layers. Development of mesoderm and its differentiation. Development of the notochord. Development of the cardiovascular system. Primitive blood circulation. Heart development 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. Aortic arches and their derivatives. Fetal blood circulation, circulatory changes after birth Development of the digestive system. Development of foregut. Development of the liver and pancreas Development of midgut and hindgut. Fixation of intestines. Cloaca and its differentiation Development of the respiratory system. Body cavities, formation of the diaphragm Development of the urinary system Development of gonads. Differentiation of the genital ducts in both sexes Neuroectoderm and its differentiation. Histogenesis of the neural tube. Neural crest and its derivatives Development of spinal cord and brain vesicles. Critical periods in development Development of the eye and ear Teacher: RNDr. Lantová, Ph.D. Tuesday 9,15 – 10,45 Tuesday 8,00-9,00 1. summer semester Microscopy of the nervous system and skin slides: H1,2 and L2,3,4,5,8 Structure of the eye and eyelid. Microscopy: S1,4 Oral cavity and its content. Structural specialization of the oral mucosa. Microscopy of the lip and tongue: B1,3,4 Tonsils – structure and function. Waldeyer´s ring. Microscopy of the palatine and lingual tonsils: B4,5. Taste buds, their distribution, chemical sensation Salivary glands. Serous and mucous cells, duct system. Saliva. Microscopy of the parotid, submandibular and sublingual glands: B6,7,8 Teeth and associated structures. Microscopy of teeth slides: B2 Tooth development. Enamel organ, differentiation of odontoblasts. Amelogenesis and dentinogenesis. Development of the tooth root, cementum and periodontal ligament. Microscopy: X5 Tooth eruption. Development of permanent tooth buds. Anomalies of teeth Development of the face. Development of the oral and nasal cavities. Cleft lip, jaw, and palate. Development of the tongue Development of primitive pharynx – pharyngeal clefts, pouches, arches. Development of endocrine glands derived from stomodeum and from the primitive pharynx. Birth defects involving the pharyngeal region Development of axial skeleton Development of muscles and limbs Development of body form and umbilical cord. Fetal membranes Placenta, structure and function. Anomalies of placenta and umbilical cord Microscopy : X3,4 Intrauterine growth. Parturition. Twins and other types of multiple pregnancies Credits Recommended Literature: Sadler T.W.: Langman´s Medical Embryology, Lippincot Wiliiams and Wilkins, 2006, 2011, 2012 Moore,K.L. – Persaud, P.V.N.: Before We Were Born: Essentials of Embryology and Birth Defects, 8th Ed., Saunders Elsevier, 2008, 2013 Additional Literature: Berkovitz B.K.B., Holland G.R., Moxham B.J.: Oral Anatomy, Histology and Embryology, Mosby, 2009 Nanci,A.: Ten Cate´s Oral Histology. Development, Structure and Function, Mosby, 2008