B81131 – HISTOLOGY and EMBRYOLOGY 1,2
week
LECTURES
Teacher: Ass. Prof. MUDr. Jirsová
Wednesday 10,30 – 12,00
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PRACTICAL LESSON
winter semester
Teacher: RNDr. Lantová, Ph.D.
Wednesday 13,00 – 15,15
Cell – morphological and functional unit of the organisms. Plasma
membrane, membranous organelles – structure and function
Non-membranous organelles. Cell inclusions. Cell cycle. Mitosis
and meiosis
Tissues – classification, general structure and function.
Epithelial tissue – cell adhesion and intercellular junctions, cell
surfaces modifications
Connective tissues. Extracellular matrix – ground substance and
fibres. Types of the connective tissue and their function
Muscle tissue. Structure of skeletal, cardiac, and smooth muscles.
Myofibrils and myofilaments, contractile mechanism
Nerve tissue. Neuron – structure and function. Synapses. Glial
cells and their function. Nerve fibers and their sheaths
Composition of the blood. Erythrocytes, leukocytes and
thrombocytes. Hemopoiesis
Cardiovascular system. General structure of the blood vessels.
Heart – structure of the wall. Lymphatic vascular system
Immune system. Lymphoid organs. Mononuclear phagocyte
system
Endocrine system. Hypothalamus and pituitary gland. Structure
and function of the endocrine glands
Digestive system. General structure of the wall of the alimentary
canal. Structural specialization of the tunica mucosa of stomach,
small and large intestines
Respiratory system. Tunica mucosa of the respiratory ways.
Lung – structure, respiratory portion, air-blood barrier
Urinary system. Structure and function of the kidney
Male genital system. Testis, spermatogenesis
Uptake and processing of tissue samples for microscopic examination.
Light microscope. Microscopy
Basic staining methods, histochemistry and immunohistochemistry.
Microscopy: T1,2,3,4,5,7,8
Epithelial tissue. Classification of epithelia, basic types – their structure and
function. Microscopy: T1,2,4,7,8
Female genital system. Ovary, follicle development.
Uterus, cyclic changes of the endometrium during menstrual cycle
Microscopy of the ovary, uterine tube, uterus, and vagina: C11,13,14,16
Credits
Connective tissue fibers and their staining. Loose and dense connective tissue,
adipose tissue. Hyaline, and elastic cartilages. Microscopy: A1,4,5,6,8,10
Lamellar compact and spongy bones. Intramembranous and endochondral
ossification. Microscopy: A12,14,15,16
Smooth, cardiac, and skeletal muscles. Types of neurons. Structure of the
peripheral nerve. Microscopy: A17,18,20 and L2,3,4,8
Preparation and evaluation of the blood smear. Microscopy of the peripheral blood
smear. Morphology of the peripheral blood elements
Aorta. Neurovascular bundle – muscular artery, vein, peripheral nerve. Inferior vena
cava. Microscopy: F1,2,3,5,6
Lymph node, spleen, and thymus.
Microscopy: G1,2,4
Pituitary gland, thyroid, and adrenal glands. Islets of Langerhans.
Microscopy: E1,2,4,5
Liver and pancreas.
Microscopy of digestive system slides: B9,10,12,15,16,17,18
Larynx, trachea, lung. Microscopy: D1,2,3,4
Urinary passages. Microscopy: U1,3,4
Excretory genital ducts, accessory genital glands. Microscopy: C6,7,10
Recommended Literature:
Mescher, A.L.: Junqueira´s Basic Histology, Lange, 2010
Ross,M.H. - Pawlina,W.: Histology: Text and Atlas , Williams and Wilkins, 2006, 2011
Junqueira,L.C. - Carneiro,J.: Basic Histology: A Text and Atlas, Lange, 2005
Kuehnel,W.: Pocket Atlas of Cytology, Histology and Microscopic Anatomy, Thieme Publishing Group, 2003 – also available at http://uvi.lf1.cuni.cz/en/thiemeelectronic-book-library