Psychotherapeutic treatment program for posttraumatic stress disorder: prospective study of 70 war veterans Dolores Britvić, M.D. Vesna Antičević, psychologist Ivan Urlić, M.D., Ph.D. Goran Dodig, M.D., Ph.D. Branka Lapenda, M.D. Vesna Kekez, psychologist Department of psychiatry, Clinical hospital Split, Split University School of Medicine, Split, Croatia Correspondence: Britvić Dolores Klinička bolnica Split Šoltanska 1 21 000 Split Tel. 00 385 21 557 411 00 385 21 220-586 Fax 00385 21 557 507 dbritvic@globalnet.hr Short title: Outpatient psychotherapeutic program for PTSD Key words (not in title). Combat, outcome, group psychotherapy, depression, quality of life. Abstract: Aim. To assess the effectiveness of psychotherapeutic model of treatment of war veterans with posttraumatic stress disorder (PTSD), by evaluating the symptoms of PTSD, associated neurotic symptoms, ways of coping with stress, and indicators of quality of life and depressiveness. Methods. Prospective cohort study included 77 war veterans who took part in a psychotherapeutic model of treatment lasting 40 weeks. On each visit, there were three types of group sessions: socio-therapeutic, psycho-educative, and traumafocused groups. Groups consisted of 10-12 veterans, and each session lasted 60 minutes. Mississippi scale for PTSD was used for assessing the intensity of PTSD, Crown-Crisp Index for neurotic symptoms, Inventory of dispositional and situational coping with stress for ways of coping with stress, Quality of Life Scale for indicators of quality of life, and Beck Depression Inventory for depression at the beginning and the end of psychotherapeutic program. Results. Seventy veterans finished the whole course of treatment. After the completed psychotherapeutic treatment program, there was an increase in problemoriented coping with stress (t=-2.073, p=0.042), and coping by avoidance (t=-2.803, p=0.007). BDI scores at the end of treatment were significantly lower than at the beginning (t=4.563, p=0.000). There were no significant changes in symptoms of PTSD (t=1.730, p=0.088), neurotic symptoms and scores on the QLS (t=-1.825, p=0.072). Conclusion. Revealing and working through the traumatic events facilitated gradual ending of the process of pathologic grief, which resulted in reduction of depression. Other therapeutic factors (altruism, giving hope, developing social skills) contributed to the achieved therapeutic effects. Introduction Ten years after the end of war in Croatia, there are still many patients showing a complex posttraumatic response to traumatic experiences (1, 2). Brutality and repetitive nature of traumatic battlefield experience profoundly changes motives, spiritual and existential views on life, as well as the individual feeling of meaning and purpose (3). An inner world of deeply repressed emotions reflects itself on the totality of intrapsychic and interpersonal layers of personality, causing changes in biological functions, strong anxiety, and often depression and changes in quality of life (4-7). Group psychotherapy, which goes deep into intrapsychic and interpersonal spheres, is a necessary part of integral approach to treatment of psychotrauma (8,9). Literature on group therapy of posttraumatic stress disorder (PTSD) gives descriptions of different therapeutic techniques, each of them mostly focusing on a particular psychological disturbance such as anxiety, fear or avoidance behavior (10, 11). The majority of recent studies suggests multidimensional approach using psychoeducation, support, anxiety relief, and life-style modification, all of which have a goal of normalizing the stress reactions and reducing the maladaptive psychobiological processes (8-10). Various models are recommended for this purpose, but there is still no common stand on how these integral techniques should be applied. The fact that only a few studies evaluated the effect of such treatment (12-15) contributes to the problem. Aiming towards the above mentioned in treatment of PTSP, we implemented a psychotherapeutic program consisting of socio-therapeutic, psycho-educative and dynamic-oriented group approach. The purpose of this study was to assess the effectiveness of such psychotherapeutic program by evaluating the symptoms of PTSD, neurotic symptoms, ways of coping with stress, depressiveness and indicators of quality of life. Patients and methods Participants The study included war veterans who came for treatment in the Regional Center for Psychotrauma at the Department of Psychiatry of the Clinical Hospital Split, from January 2003 to October 2005. Detailed screening procedure was performed prior to admission to identify the veterans with PTSD according to the International Classification of Diseases, 10th revision (16). For this purpose, we used clinical interview and patients’ medical records (findings of psychiatrist and psychologist, including intelligence test results). Inclusion criteria were age between 25 and 65 years and the diagnosis of PTSD as a consequence of traumatic experiences while serving in the Croatian Army units. Exclusion criteria were central nervous system disease, alcohol and drug addiction, acute psychosis, severe form of PTSP which precludes participation in the treatment program, and subnormal intelligence. Data on participants' intelligence were obtained from their psychological findings. Therapeutic technique Therapeutic program was carried out for 40 weeks. At each meeting, patients participated in three types of groups: 1) socio-therapeutic, 2) psycho-educative, and 3) dynamic-oriented group for working through traumatic experience. Groups consisted of 10-12 veterans, and each session lasted 60 minutes. On each occasion, participants would stay in the Center for a total of 5 hours. The socio-therapeutic group was led by a social worker, psycho-educative group by a psychiatrist or psychologist, and dynamic-oriented group by group therapists (psychiatrist or psychologist). The primary goal was to help war veterans establish a feeling of trust, security and reciprocity. The way of conducting the group sessions was active, supporting, facilitating and stimulating. Socio-therapeutic group. Supportive techniques were used to foster reciprocity, acceptance, altruism, universality and better communication. At the beginning of the program, the most recurring themes were reality's problems such as obtaining the status of military war invalid and the right to pension. Later on, focus was transferred on solving current problems at work, in family and society. The participants were encouraged to improve the communication with their family members, to take up their family duties more actively, and to strengthen their male roles. Positive transfers of the group members were crucial in facilitating acceptance of new patterns of behavior (3, 8- 10). Psycho-educative group. Participants were informed about the symptoms of PTSD, its consequences on the family, professional and social functioning, as well as the ways of coping with mental disturbances by using the techniques of conflict resolution and other social skills. Participants were able to recognize the symptoms and face the fact that their everyday problems in interpersonal relationships were the result of disorder caused by a traumatic experience. These insights were well received by the members of the group, and brought them a sense of relief. Mirroring with other group members who had the similar or same symptoms stimulated self-discovering and self-acceptance, and contributed to the feeling of unity, connection and acceptance by others (3, 10). Trauma focused group. Participants were stimulated to disclose their traumatic experiences and reconstruct them in detail, describing location, period of the day, fellow soldiers, enemies, as well as their emotional reactions at the time and after the traumatic event. Especially at the beginning of the program, but also during the whole course of treatment, there was a strong resistance to disclosure and working through traumatic experience. A valuable signpost in revealing the trauma was bringing up dreams of the traumatic event, dreams with content very similar to the traumatic event, or with strong emotions of fear and panic. Presentment of traumatic memories would provoke strong feelings in the whole group, and some of participants would be moved to open up, while others would react by acting out and leaving the session, becoming verbally aggressive towards the therapist, or missing the next session. Opening traumatic memories threatened intrapsychic balance, so we often heard complaints about intensified symptoms, sleep disturbances, isolation and withdrawal from family members. In the beginning phases, participants primarily revealed traumatic events associated with the fear for their own existence, grief for fellow soldiers who were killed, and the guilt of surviving. As confidence in the group and therapists increased, revealing expanded to the traumatic events associated with strong feelings of guilt (17, 18). At the very beginning of the program, the emphasis was on establishing basic security and trust in the group and the therapist. Here we often encountered issues related to distrust in the staff and group leaders. After approximately 15 meetings, cohesion and connections between the group members would develop, which helped to overcome the resistance and to disclose traumatic experiences as well as the problems in social relations and in family. With increased closeness and connections between the group members, the act of revealing traumatic memories was accompanied by feelings of sadness and grief. Group members would become very vulnerable due to the grief for killed fellow soldiers and due to the loss of ego idealizations because of what happened on the battlefield. Opening up of painful traumatic memories in some participants provoked worsening of the clinical picture, which in two cases required hospitalization. In this stage of group work, participants sometimes expressed suicidal phantasies, or described the attempts of suicide, either their own or of their friends and fellow combatants. The atmosphere was much more comfortable and easier in the last third of the program. Outcome measures Mental state of participants was evaluated by the following self-assessment instruments: A) Mississippi scale for assessing the symptoms of post-traumatic stress disorder (MPTSD), B) the Crown-Crisp Experiential Index, C) Inventory of dispositional and situational coping with stress, D) Quality of Life Questionnaire, E) Beck Depression Inventory. Evaluation was done in two time points: before the beginning of treatment, and at the end of the program. The study was approved by the Ethics Committee of the Split University School of Medicine and the Clinical Hospital Split. Patients were informed about the study and gave a written consent. Mississippi scale for assessing the symptoms of post-traumatic stress disorder (MPTSD) is considered one of the best instruments for assessing the intensity of PTSD in war veterans, and correlates highly with other measures for PTSD. It consists of 35 items with a series of 5-point Likert-type responses ranging from „totally incorrect“ to „completely correct“. The sum of individual responses gives a continuous result as a measure of the intensity of PTSD symptoms. The scale has a good reliability and validity, as well as the sensitivity and specificity (19). Crown Crisp Experiential Index (CCEI) is used to assess neurotic symptoms and measure changes before and after an intervention (20). Index is objective and satisfactorily meets two basic psychometric criteria: reliability and validity (20,21). Inventory of dispositional and situational coping with stress (COPE) consists of 17 theoretically derived scales which describe three factors of the higher order: problemoriented coping, emotions-oriented coping, and coping by avoidance. The inventory is a Croatian version of original COPE questionnaire, from which 15 scales were taken, and two more were added to include the answers specific for this area (22, 23). Quality of Life Scale consists of 21 items which measure various aspects of quality of life. The scale is used: 1) as a synthetical, global indicator of the state of an individual, 2) for assessing effects of various medical or psychotherapeutic interventions on the quality of life of individual, and 3) for assessing the quality of life as a dependant variable in scientific research (24). Beck Depression Inventory (BDI) consists of 21 items by which the intensity and structure of the symptoms of depression is evaluated. Symptoms are defined according to the criteria in the Diagnostic and Statistical Manual of Mental Disorders (DSM IV). The questionnaire is sensitive to the changes which are the result of psychotherapy or pharmacotherapy. It well discriminates mild, medium and severe depression. The reliability coefficient is 0.80 (25). Statistics The variables are evaluated descriptively (mean and standard deviation), and analyzed with T-test for dependant samples. Software program SPSS 12.0 for Windows (Chicago, IL: SPSS Inc., 2003) was used for data analysis; significance level was set at 0.05. Results A total of 151 war veterans were examined (Figure 1). Forty-four veterans did not meet inclusion criteria: diagnosis of PTSD was not confirmed in 30 veterans, 2 were addicted to psychoactive drugs, 3 were diagnosed with acute psychosis, 4 were of subnormal intelligence, and 5 had a severe disorder that required hospital rather than outpatient treatment. Sixteen veterans refused to participate in the study and 14 did not answer the invitation for group psychotherapy. Seventy-seven patients began the psychotherapy, and 70 completed the whole course of treatment. All patients were men. In the group of veterans who completed the psychotherapy, more than a half (n=37) were in the 30-40 age group, and 24 were in the 40-50 age group. Mean age was 39.5±6.09 years. Most of the participants (n=57) had high school education (10-12 years of school). The majority (n=54) was married, 14 were single, and no one was divorced. Most of the participants (n=60) spent less than 3 years on the battlefield (Table 1). Out of 7 patients who quit therapy, 4 did it at the very beginning. They stated complexity and long duration of the program as the reasons for quitting. Two patients got jobs after three months and decided to stop coming to the therapy. One quit without explanation. Total score of symptoms of PTSD as measured by the MPTSD were lower at the end than at the beginning of the program, but the difference was not significant (t=1.730, p=0.088). On the CCI scales of anxiety, phobia, obsession, somatization, depression and hysteria, there were no significant differences between the results at the beginning and end of the program (Table 2.) Results of Inventory of dispositional and situational coping with stress showed significant differences in two out of three categories: problem-oriented coping and coping by avoidance. Problem-oriented coping significantly increased from the beginning (M=45.9917.85) to the end (M=49.5315.95) of the program (t=-2.073, p=0.042). Emotions-oriented coping also increased, but not significantly (t=-0.833, p=0.408). Coping by avoidance increased from the beginning (M=79.7726.22) to the end (M=88.5426.52) of program, and the difference was significant (t=-2.803, p=0.007). Results of the Quality of Life Scale at the beginning of the program (M=57.6111.39) were lower than at the end (M=59.9110.37), but the difference was not significant (t=-1.825, p=0.072). Significant difference was observed on the results of Beck's Depression Inventory (t=4.563, p=0.000). Depressiveness decreased from the beginning of the program (M=38.4110.23) to the end of it (M=29.198.49) (Table 2). Discussion The results of this study show that the psychotherapeutic treatment program leads to changes in ways of coping with stress and reduces depressiveness, but it does not bring significant changes in symptoms of PTSD, neurotic symptoms and scores on QLS. Guidelines for treatment of PTSD recommend the combined use of therapeutic techniques, but the results of available studies are varying. Hence there is a need for evaluation of the multidimensional approach also on the population of Croatian war veterans suffering from the chronic PTSD. In such an evaluation, it is not possible to assess the effect of each individual technique. The limitation of the study is a relatively small number of participants, which is resulting from the very nature of therapeutic process. In assessing the effect of treatment, the problem of control group arises. The use of control group in psychotherapy is questionable, because it is very difficult to find a group which would be similar to the treated group in all relevant characteristics. This study did not include follow-up data collected a year after the end of treatment. This, together with a comparison with war veterans on the waiting list, will be analyzed in the continuation of this study. Several studies evaluated treatment programs consisting of psychoeducative groups, thematic groups, and in some instances groups for working through traumatic experience (26,27). Described programs were very diverse, conducted in-hospital or out-of-hospital, lasting for 90 days, 12 weeks and up to 4 months. Such a diversity does not allow appropriate comparing with the results of our study. Furthermore, the results of previous studies are unequal. Some reported reduction in the intensity of the PTSD symptoms, while others found no change (12-15, 26, 27). Most studies showed improvement in interpersonal relationships and family functioning, and some observed an attenuation in feelings of guilt, shame and loneliness (13, 14, 28). Our study did not find a significant reduction of the PTSD symptoms measured by the MPTSD and neurotic symptoms, and no increase in the QLS scores, which is in accordance with the results of some previous studies (13,29,30). An earlier study by this group found that a long-term dynamic-oriented group psychotherapy reduces the symptoms of PTSD in war veterans, which is an indication that such a method is more effective than a combined psychotherapeutic treatment program lasting only 40 weeks. These findings confirm the conclusions by this group about the need of longterm group psychotherapy of chronic PTSD to reduce the symptoms of this disorder (10, 31). Results of the Inventory of coping with stress (COPE), conducted at the end of treatment, showed an increase in problem-oriented coping, but also in coping by avoidance. The increase in problem-oriented coping indicate an improvement in communication with environment, more active taking of roles within the family and work place, and less difficulties in controlling aggression, all of which is consistent with the findings of previous studies (14). Beside the more frequent use of this positive way of coping with stress, there is also an increase in coping by avoidance. This finding can be a sign of a tendency to avoid conflicts, which results from the therapeutic efforts to acquire these skills. The results demonstrate the importance of psychoeducational and sociotherapeutic aspect of treatment, which includes receiving information about the PTSD symptoms, understanding the reasons behind the intrapsychic and interpersonal problems, but also acquiring the new communication skills and conflict resolution skills in an atmosphere of trust, universality and connection with others (8,9,10). Data on depression were obtained by two tests. Results of the CCI depression scale showed no change in depression when compared with the level from the beginning of treatment. A reduction of depression was observed when measured by the BDI. This discrepancy can be explained by different sensitivity of two tests, out of which CCI evaluates depression as a personality trait, and BDI the present emotional state. Observed improvement can be explained from the viewpoint of resolving the process of pathologic grief, but also the positive effects of other therapeutic factors during the group treatment (32,33). In the dynamic-oriented group trauma-focused group, patients are able to reveal and work through long-suppressed, emotionally invested memories of traumatic experiences. Psychotherapeutic interventions enabled patients to re-live the emotions of guilt and shame in a new context of group setting (18, 33, 34). Revealing and working through the traumatic events facilitated gradual ending of the process of pathologic grief, which resulted in reduction of depression. 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Demographic characteristics of 70 war veterans who participated in the psychotherapeutic treatment program in the day hospital of the Regional Center for Psychotrauma Split. n = 70 Characteristic s Years 30 0 30-39 37 40-49 24 50-59 9 > 60 0 Education Elementary 7 school High school 57 College and 6 university Marital status 54 Married Single 14 Divorced 0 Time spent on the battlefield < 3 years 60 3 - 4 years 7 > 4 years 3 Table 2. Results of assessment of 70 war veterans who participated in the psychotherapeutic treatment program in the day hospital of the Regional Center for Psychotrauma Split. Admission Discharge MPTSD* 134.4816.328 132.0416.377 Anxiety 12.632.240 Phobia T P 1.730 0.088 13.01.985 - 1.564 0.122 7.87 2.718 8.403.246 - 1.637 0.106 Obsession 8.092.653 8.703.085 - 1.875 0.065 Somatization 12.163.300 12.912.739 - 1.968 0.053 Depression 11.833.026 11.812.666 0.049 0.961 Hysteria 3.092.339 3.272.359 - 0.714 0.478 Problem- 45.9917.858 49.5315.958 - 2.073 0.042† 18.5610.459) 19.378.131 - 0.833 0.408 88.5426.524 - 2.803 0.007† oriented coping Emotionsoriented coping Coping by 79.7726.224 avoidance Quality of life 57.6111.398 59.9110.374 - 1.825 0.072 Becks 38.4110.231 29.198.496 4.563 0.000† Depression Inventory * Mississippi scale for assessing the symptoms of post-traumatic stress disorder. † Statistically significant difference between two time points (p<0.005). Figure 1. Flow of patients through the study. 151 war veterans examined 44 did not meet inclusion criteria 16 refused to participate in the study 14 did not answer the invitation for group psychotherapy 77 began the treatment program 7 quit the program 70 completed the treatment program