SAMPLE QUESTIONS FOR CELLULAR NEUROSCIENCE NSC4352 Q1. List FIVE distinct roles played by Glia Q2. For two similar sensory Neurons-Neuron A and Neuron B- if the input signal ( a receptor potential) has a longer duration for Neuron B, pick the most appropriate answer: a) Each action potential for Neuron A is smaller in amplitude relative to the action potential for Neuron B b) Each action potential of Neuron A is lesser in duration relative to the action potential of Neuron B c) The action potentials for Neuron A are lesser in number relative to the action potentials for Neuron B d) The action potentials for Neuron A exhibit less plasticity than the action potentials for Neuron B Q3. TRUE or FALSE . The Golgi complex extends into the axons but not into the dendrites. Q4. For K+, Na+, Cl- if their permeabilities are respectively 30:2:5 , and the concentrations of each ion in mM are as given below (values given may not be physiological values) find out the resting membrane potential in mV. Show your calculation in the space provided below: Intracellular Extracellular Potassium 600 30 Sodium 100 400 Chloride 60 360 Q5. At the peak of the action potential, the electrochemical driving force is the least for: a) Na+ b) K+ c) Cld) Ca++ Q6. If the equilibrium potential of a univalent cation is 116mV, a possible extracellular and intracellular concentration would be: a) intracellular 10mM and extracellular 200mM b) intracellular 24mM and extracellular 2400mM c) intracellular 260mM and extracellular 26mM d) intracellular 1400mM and extracellular 14mM e) intracellular 400 mM and extracellular 40mM Q7. Describe temporal summation of synaptic inputs. Q8. The following graph shows the response of the membrane potential (∆Vm) to a step current pulse. Line X shows a response that has the properties of : a) a purely resistive element b) a purely capacitive element c) a combination of both a resistive and a capacitive element Q9. For a spherical neuron having a radius of 0.1cm, a specific membrane resistance (Rm) of 3.14Ω.cm2 calculate the total input resistance in ohms(Ω). Show your calculation in the space provided below. Q10.Describe the voltage clamp technique