Biology 122, Quiz 6, 2011 Name:______________________________ Directions: 1) Print your name LEGIBLY on BOTH the scantron form and this question sheet; 2) Fill in the scantron form. Turn both the scantron form and this answer sheet in. There are 10 questions, each worth 1 point. 1. Since both the strands of a DNA molecule are complimentary to each other, either one of the strands can be used as a _______ to reconstruct the other. A. B. C. D. copy basis compass template 2. The synthesis of the growing chain of DNA is carried out by adding nucleotides to the ______________ end. A. B. C. D. 8' 3' 5' 1' 3. The units of hereditary information that are represented by alleles is(are) called ______________. A. B. C. D. genes DNA RNA chromosomes 4. DNA consists of two antiparallel strands of nucleotide chains held together by… A. B. C. D. E. peptide bonds. polar covalent bonds. ionic bonds. hydrogen bonds. complementary base pairing bonds. 5. At the DNA replication fork, the primase enzyme… A. creates a short RNA primer complementary to the RNA template. B. creates a short DNA primer complementary to the RNA template. C. creates a short DNA primer complementary to the DNA template. D. creates a short RNA primer complementary to the DNA primer. E. creates a short RNA primer complementary to the DNA template. 6. As the two strands of DNA are unraveled at a replication fork, an enzyme relieves the strain on the two strands produced by the untwisting of the parental double helix. The enzyme is… A. DNA polymerase. B. DNA ligase. C. DNA gyrase (topoisomerase). D. DNA 5’ 3’ nuclease. E. DNA 3’ 5’ nuclease. 7. Griffith, a British microbiologist, used bacteria and mice to demonstrate transformation, a discovery that ultimately led to the conclusion that DNA was the molecule of heredity. Transformation is… A. the ability for bacterial homologous chromosomes to transform themselves into an exact copy, sometimes referred to as DNA replication. B. the ability of the nucleus of a cell to regenerate and repair itself when damaged by bacterial infections. C. the ability of the infected mice to transform the bacteria from pathogenic to nonpathogenic during the experiments. D. the ability to transfer genetic materials from one cell to another. E. the ability for the nucleus of a bacterial cell to bypass the process of DNA replication by transforming into a spore during unsuitable environmental conditions. 8. In which of the following cells might you expect to find the highest level of telomerase? A. intestinal stem cells that replenish the lining of the gut in mammals B. oocytes in the mammalian ovary that are arrested in prophase of Meiosis I C. neurons in the brain that function to process auditory input D. mammalian skeletal muscle cells 9. In DNA replication, a new nucleotide (NN) is joined to a growing strand by covalently linking the NN to the last added nucleotide (LAN) of a growing strand. Which of the following pairs of atoms are linked in this process? A. the oxygen in the ribose sugar ring of the LAN and the 3’ oxygen of the NN B. the oxygen in the ribose sugar ring of the LAN and the alpha phosphate of the NN C. the 3’ oxygen of the ribose sugar of the LAN and the alpha phosphate of the NN D. the 1st nitrogen of the nitrogenous base of the LAN and the 1st carbon of the ribose sugar of the NN 10. Which of the following statements about DNA replication is FALSE? A. DNA replication begins at a defined origin, and proceeds bi-directionally from that point. B. Eukaryotic chromosomes face an end replication problem, but bacterial chromosomes do not. C. DNA polymerase synthesizes new strands of DNA exclusively in the 3’ 5’ direction. D. the requirements of DNA polymerase include dNTPs (deoxyribonucleotides) and a primed template.