ABDULLAH A. ALANGARI P.O. BOX 89805, RIYADH 11629, SAUDI ARABIA MOBILE +966506287276 – EMAIL: ALANGARI100@GMAIL.COM EDUCATION 5/2007 – 12/2007 6/2008 – 8/2008 Visiting Scholar Division of Infection, Inflammation, and Repair School of Medicine, University of Southampton Southampton, UK 7/2000 – 6/2003 Fellow in Allergy & Immunology Children’s Hospital Harvard Medical School Boston, Massachusetts, USA 6/1997 – 6/2000 Pediatric Resident Massachusetts General Hospital Harvard Medical School Boston, Massachusetts, USA 10/1994 – 4/1997 Pediatric Resident King Fahad National Guard Hospital Department of Pediatrics Riyadh, Saudi Arabia 7/1993 – 7/1994 Intern King Khalid University Hospital King Saud University, College of Medicine Riyadh, Saudi Arabia 9/1987 – 6/1993 Medical Student King Saud University College of Medicine Riyadh, Saudi Arabia 1 CERTIFICATIONS 8/2003 American Board of Allergy and Immunolgoy 10/2000 American Board of Pediatrics 8/1995 MRCP (UK) Part 1 – Pediatrics 7/1993 MBBS with Honors 28/7/1999 The commonwealth of Massachuse tts – Board of Registration in Medicine (USA). Certificate No. 160993 13/1/2007 Saudi Commision for Health Specialties. Consultant Pediatrician. Consultant Allergist, and Immunologist. Registration ID No. 07-R-M-1150 LICENSURE WORK EXPERIENCE 1/2015 - present Professor of Pediatrics. College of Medicine, King Saud Univeristy 10/2010 – 12/2014 Associate Professor of Pediatrics. College of Medicine, King Saud University. 2005 – 9/2010 Assistant Professor of Pediatrics. College of Medicine, King Saud University. 2004 - present Consultant Pediatrician, Allergist, and Immunologis. King Khalid University Hospital. 5/2005 – 11/2008 Head of the Allergy and Immunology Unit at the department of Pediatrics, King Khalid University Hospital. 2009 – 2013 Member of the Pediatrics Allergy and Immunology Fellowship Program’s Supervising committee. 2009 – 2013 Member of the mortality and morbidity committee, Dep. Of Pediatrics, College of Medicine, King Saud University. 10/2009 – 8/2013 COMMITTEES 2 2005 – 2008 Chairman of the Undergraduate Teaching Program Committee, Dept. of Pediatrics, College of Medicine, King Saud University. ACADEMIES AND SOCIETIES AFFILIATION Fellow of the American Academy of Allergy and Immunology Member of the Saudi Scociety of Allergy and Immunology Member of the Saudi Pediatrics Association PUBLICATIONS Charbonnier L-M, Janssen E, Chou J, Ohsumi TK, Keles S, Hsu JT, Massaad MJ, Garcia-Lloret M, Hanna-Wakim R, Dbaibo G, Alangari AA, Alsultan A, AlZahrani D, Geha RS, Chatila TA. Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA. J Allergy Clin Immunol. 2015;135:217-227 Alangari AA, Riaz M, Mahjoub MO, Malhis N, Al-Tamimi S, Al-Modaihsh A. The Effect of Sand Stroms on Acute Asthma in Riyadh, Saudi Arabia. Ann Thorac Med.2015;10(1):29-33 Alangari AA. Characteristics of Patients Presenting to the Emergency Department with Anaphylaxis in Riyadh, Saudi Arabia. Journal of Taibah University Medical Sciences.2014;9(4):318-321 Alangari AA. Corticosteroids in the Treatment of Acute Asthma. Anna Thorac Med.2014;9(4):187-192 Al-Dosary K, Al-Qahtani A, Alangari AA. Anaphylaxis to Lidocain with Tolerance to Articain in a 12 years old girl. Saudi Pharmaceutical Journal.2014;22:280-282 Alangari AA, Malhis N, Mubashir M, Al-Ghamedi N, Al-Tannir M, Riaz M, Umetsu DT, Al-Tamimi S. Budesonide Nebulization Added to Systemic Prednisolone in The Treatment of Acute Asthma in Children: Doube-Blind, Randomized, Controlled Trial. Chest.2014; 145(4):772-778 Alangari AA. Normocomplementemic Urticarial Vasculitis in a Boy and his Response to Treatment. Curr Pediatr Res.2014;18(1):8-10 Alfares FA, Raddaui EM, El-Mozan MI, Alangari AA. Menetrier’s disease in a Saudi child. Saudi Med J.2013;34(11):1192-4 Alangari AA, Alsultan A, Osman M, Anazi S, Alkuraya F. A Novel Homozygous Mutation in G6PC3 Presenting as Cyclic Neutropenia and Severe Congenital 3 Neutropenia in the Same Family. J Clin Immunol.2013;33(8):1403-6 Prando C, Samarina A, Bustamante J, Boisson-Dupuis S, Cobat A, Picard C, et al. Inherited IL-12p40 Deficiency: Genetic, Immunologic, and Clinical Features of 49 Patients From 30 Kindreds. Medicine (Baltimore). 2013;92:109-122 [Erratum. Medicine (Baltimore). 2013;92:190] Book Chaper: Alangari AA. The Use of Glucocorticoids in the Treatment of Acute Asthma Exacerbations. In: Qian, X, eds. Glucocorticoids-new recognistion of our familiar friend. In tech; 2012.501-522 p. Al-Khayyat A, Al-Anazi M, Warsy A, Vazquez-Tello A, Alamri AM, Halwani R, Alangari AA, Al-Frayh A, Hamid Q, Al-Muhsen S. T1 and T2 ADAM33 single nucleotide polymorphisms and the risk of childhood asthma in a Saudi Arabian population: a pilot study. Ann Saudi Med.2012;32:479-486 Alangari AA, Alsultan A, Adly N, Massad M, Kiani IS, Aljebreen A, et al. LPSresponsive beige-like anchor (LRBA) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency. J Allergy Clin Immunol. 2012;130:481-8 Shaffiq A, Haitchi H-M, Pang Y, Alangari AA, Jones M, Marshall B, Howarth P, O’Reilly K, Davies D. A Disintegrin And Metalloprotease (ADAM)33 Protein in Patients with Sarcoidosis. Respirology. 2012;17:342-349 Sancho-Shimizu V, de Diego RP, Lorenzo L, Halwani R, Alangari AA, et al. Herpes simplex encephalitis in patients with autosomal recessive and dominant TRIF deficiency. J Clin Invest. 2011;121:4889-4902 Alangari AA, Al-Zamil F, Al-Mazrou A, Al-Muhsen S, Boisson-Dupuis S, Awadallah S, Kambal A, Casanova J-L. Treatment of disseminated mycobacterial infectionwith high dose IFN- in a patient with IL-12R1 deficiency. Clin Dev Immunol.2011, doi:10.1155/2011/691956 Alangari AA. Genomic and non-genomic actions of glucocorticoids in asthma. Ann Thorac Med. 2010;5:133-39 de Beaucoudrey L, Samarina A, Bustamante J, Cobat A, Boisson-Dupuis S, Feinberg J, et al. Revisiting human IL-12Rb1 deficiency: a survey of 140 patients from 30 countries. Medicine (Baltimore). 2010;89:381-402 Cote M, Menager M, Burgess A, Mahlaoui N, Picard C, Schaffner C, Al-Manjomi F, Al-Harbi M, Alangari A, et al. Munc18-2 deficiency casuses familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells. J Clin Invest. 2009;119:3765-73 Alangari AA, Al-Harbi A, Al-Ghonaium A, Santisteban I, Hershfield M. Purine nucleoside phosphorylase deficiency in Two Unrelated Saudi Patients. Ann Saudi Med. 2009;29:309-312 4 Alangari AA. Students’ perception of the pediatrics course in a Saudi Medical School. J T U Med Sc. 2008;3(2):135-139 Alangari AA, Abutaleb M, Albarraq A, Al-Dhowailie. Immediate adverse reactions of intravenous immunoglobulins. Cur Pediatr Res. 2008;12:31-34 Alangari AA, Abutaleb M, Albarraq A, Al-Dhowailie. Intravenous immunoglobulin utilization in a tertiary care teaching hospital in Saudi Arabia. Saudi Med J. 2008;27:477-481 Alangari AA, Lau LC, Zhou XY, Mochizuki A, Salagean EM, Salib RJ, Howarth PH, Walls AF. Differential Release and Clearance of Mast Cell and Basophil Mediators in the Uper Airways of Patients with Allergic Rhinitis. J Allergy Clin Immunol. 2008;121(2):S152 Zhou XY, Lau LC, Tabares CM, Alangari AA, Summers C, Pumphrey RS, Wild G, Escribano L, Walls AF. Mast cell proteases as new clinical markers of anaphylaxis and mastocytosis. Abstract presented at the MRC meeting in Edinburgh, UK. September, 2007 Alangari AA, Abobaker A, Kanegane H, Miyawaki T. X-linked Lymphoproliferative Disease Associated with Hypogammaglobulinemia and Growth Hormone Deficiency. Eur J Pediatr. 2006;165:-165-167 Alangari AA, Twarog FJ, Shih M-C, Schneider LC. Clinical Features and Anaphylaxis in Children with Cold Urticaria. Pediatrics. 2004;113:e313-e317 Leung DYM, Sampson HA, Yunginger A, Burks AW, Schneider LC, Wortel CH, et al. Effect of Anti-IgE Therapy in Patients with Peanut Allergy. N Engl J Med. 2003; 13; 348:986-993 (among the TNX-901 peanut allergy study group) Alangari A, Schneider L, Geha R, Nurko S, Bonilla F. Primary Sclerosing Cholangitis in a Patient with Possible Hyper-IgE Syndrome. J Allergy Clin Immunol. 2002; 109(1):S192 RESEARCH GRANTS AWARDED 2013 Grant source: King Abdulaziz City for Science and Technology. Project number: 12-NAN2537-02. Title: Design, development and evaluation of a nano- transdermal (needle-free) allergy test for diagnosis of type-1 hypersensitivity. (Co-investigator) 2012 Grant source: Deanship for Scientific Research, King Saud University. Project number: RGP-VPP-190. Title: The immunomodulatory properties of honey. (Primary Investigator) 5 2010 Grant source: King Abdulaziz City for Science and Technology. Project number: 08-MED520-02. Title: The use of inhaled corticosteroids in the treatment of acute asthma in children in the emergency room. (Primary investigator) 2008 Grant source: King Abdulaziz City for Science and Technology – Summer grant. Project title: The Role of ADAM33 in Asthma. (Co-investigator) 2007 Grant source: British Council. Project Title: Investigation of the Potential for Differential Activation of Mast Cells and Basophils using new Assays for Biochemical Markers.(Co-investigator) 2006 Grant source: Research Center, College of Medicine, King Saud University. Project Number: 05-519. Title: The role of IFN- in the treatment of disseminated mycobacterial infection in patients with IL-12R1 deficiency.(Primary investigator) 2005 Grant source: King Abdulaziz City for Science and Technology. Project Number: 10-26-420. Title: Genotyping and phenotyping of Saudi patients with chronic granulomatous disease. (Co-investigator) 6