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MAKE YOUR STUDIES COUNT
Pearls for Effective Lab/Imaging Consults
James L. Fanelli, OD, FAAO
Introduction
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Why Order Imaging Test
Co-Management vs. Direct Involvement
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Clinical Confirmation
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refer vs. orchestrate
confirmatory diagnosis
Adjunct to Thorough Examination

covering the bases
What is the Right Radiology Test?
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Plain Film X-Ray
Computed Tomography (CT)
Magnetic Resonance Imaging (MRI)
Magnetic Resonance Angiography (MRA)
Other?
Clinical Indications for CT over MRI

Assessment of Bony Abnormalities
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Detection of Lesion Calcification
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i.e.. Retinoblastoma; Chronic Sinusitis
Detection of Bony Destruction
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i.e.. Fractures
i.e.. Metastatic Disease
Assessment of Sinuses
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i.e.. Blowout Orbital Emphysema
Clinical Indications for CT over MRI

Assessment of Hyperacute Hemorrhage
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Orbital or Intracranial
Orbital Lesions unless Surface Coil Technology is used
Where MRI is Contraindicated
MRI Contraindications
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Ferromagnetic Ocular or Orbital Foreign Body
Pacemakers
Metallic Cardiac Valves
Non-MRI Compatible Intracranial Aneurysm Clips
Patient Limitations
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time of testing and postural demands
size of the patient
Common Errors in Neuro-Imaging
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The Wrong Scan for the Problem
The Wrong Area Imaged
The Wrong Technique Requested (or the correct technique
not requested)
Poor Communication between Clinician and Radiologist
Lack of recognition of Clinical Situations not Requiring
Imaging
When NOT to Order Imaging
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Typical Migraine Headache
Patient with Typical Microvascular Cranial
Mononeuropathy (i.e.. VI N Palsy with Diabetes)
Patient with Clear Evidence of MG
Hysterical or Malingering Patients
Include Contrast Material in MRI???
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Always Include Gadolinium Contrast with MRI of Brain
and Orbits EXCEPT:
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Trauma where CT is better choice
Known vascular malformations
Stroke (Infarction or Hemorrhage)
Previous Hypersensitivity to Gad or other Contrast Media
Has MRA Replaced Conventional
Angiography?
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MRA is Safe and Non-Invasive
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can screen for arterial stenosis, venous occlusions, AV
malformations, and aneurysms
MRA Fails to Demonstrate 20% of Cerebral Aneurysms
Conventional Angiography remains the “Gold
Standard” for:
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Exclusion of Aneurysms
Surgical Planning
Accurate Diagnosis
Are All MRI Scanners Equal?
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Quality Determined By:
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strength of magnetic field
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size of the magnet
gradient coil strength and technology
surface coil technology
software
Are All MRI Scanners Equal?

Open MRI Scanners are Not as Good as Conventional
Scanners
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low field strength therefore lower spatial resolution
image capture time increased therefore more susceptible to
motion
do not allow orbital coils
Still Better than CT for Soft Tissue Analysis
What About Fat Suppression?
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Structures that are Hyper-Intense (blood, contrast
material) can be hidden when juxtaposed to orbital fat
Used in conjunction with gadolinium
Mandatory on any MRI study of the optic nerves
Clinical Case:
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SUSPECTED PATHOLOGY
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Optic Neuritis
PREFERRED SCAN
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MRI Brain and Orbits
Pearls...
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MRI of Brain and Orbits with and w/o Gadolinium, with
fat suppression. 2 mm sections
DX: Left Optic Neuritis
R/O: Optic Nerve Mass or Compression
R/O: Demyelination
Clinical Case:
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SUSPECTED PATHOLOGY
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Orbital Tumor

PREFERRED SCAN
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MRI/CT Orbits
Pearls...
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MRI of Orbits, with gadolinium, with fat suppression, 2
mm sections
R/O Tumor/Mass
CT in lieu of MRI if mass is believed to be of bony origin
Clinical Case:

SUSPECTED PATHOLOGY

Orbital Trauma

PREFERRED SCAN
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CT Orbits
Pearls...
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CT Orbits, axial and coronal views, without contrast
DX: left orbital trauma
RO: orbital floor (or medial wall) Fx.
Clinical Case:
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SUSPECTED PATHOLOGY
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Pituitary Tumor

PREFERRRED SCAN
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MRI Brain
Pearls...
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MRI of Brain, with attention to sella, with and w/o
gadolinium
DX: bitemporal visual field defects
RO: Pituitary abnormality
Clinical Case
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SUSPECTED PATHOLOGY
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III N. Palsy
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PREFERRED SCANS
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MRI & MRA Brain
Pearls...
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MRI/MRA Brain with gadolinium
DX: Left Third Nerve Palsy
RO: aneurysm at junction of Posterior Communicating A.
and Internal Carotid A.
Clinical Case:

SUSPECTED PATHOLOGY
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Homonymous Hemianopsia (asymptomatic)
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PREFERRED SCAN
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MRI Brain
Pearls...
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MRI of Brain with and w/o gadolinium
DX: Left Homonymous Hemianopia
RO: Lesion in Right Post-Chiasmal Visual Pathways
Clinical Case:
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SUSPECTED PATHOLOGY
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Homonymous Hemianopsia (acute and in distress)
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PREFERRED SCAN
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CT Brain
Pearls...
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CT Brain with and w/o enhancement
DX: Left Homonymous Hemianopia
RO: Right Post-Chiasmal Visual Pathway Lesion, Acute
Infarction Suspected
Clinical Case:
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SUSPECTED PATHOLOGY
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IV or VI N. Palsy (non-traumatic)
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PREFERRED SCAN
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MRI Brain
Pearls...
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MRI of Brain with and w/o gadolinium, with emphasis on
midbrain and Ventricular System
DX: Isolated IV or VI Palsy
RO: Posterior Fossa Mass or Mass Effect
Clinical Case:
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SUSPECTED PATHOLOGY
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Bilateral Optic Atrophy (Progressive Pallor)
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PREFERRED SCAN
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CT Brain
Pearls...
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CT Brain with and w/o contrast, 5 mm axial and coronal
sections
DX: Progressive Optic Atrophy
RO: Organic Brain Syndrome
(don’t forget the heavy metal screening)
Clinical Case:
 Suspected Pathologies:
Multiple Diagnostic Lab Studies Required
Anemia
Hyperlipidemia
Wegener’s
Collagen Vascular
Pearls
 Pearls for each lab study discussed
Concluding Pearls
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Communicate Clinical History
Communicate Suspected Pathology
Ask for Attention to Specific Anatomical Areas
Specify Preferred Views (eg. 2mm coronal views)
Specify Preferred Technique (eg. Fat suppression)
Concluding Pearls
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Don’t Be Afraid to Ask
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Don’t Be Afraid to Tell
 Questions?
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