Institute for Engineering in Medicine Request for Proposals Exploratory Grant Proposals Fiscal Year 2014 Program Features: Highly innovative and transformative ideas to advance fundamental research or the translation of discoveries to significant clinical applications. The program should reflect new ideas of the proposing investigators or a new collaboration between one faculty each in AHC and CSE. Research Areas: Proposals can be in any area of engineering that is related to biomedicine and health, with the expectation that the research aims to strengthen University of Minnesota capabilities in addressing significant biomedical and health problems using engineering approaches. Proposals in Cardiovascular Engineering, Neuroengineering, Cellular and Molecular Bioengineering, Medical and Biological Imaging, and Medical Devices research are particularly encouraged. These programs should involve fundamental or translational science, and should be designed with a specific hypothesis or deliverable that can produce pilot data for seeking new external funding or for providing the basis for new and significant intellectual property. Preliminary data are not required but the applicants should demonstrate their ability and expertise to succeed with the proposed research. Research Proposal: The research proposal must have a well defined hypothesis or deliverable. Priority will be given to explore novel ideas with collaborative efforts by faculty from AHC and CSE, and to projects that are likely to lead to external funding. All PIs and Co-Is must be IEM members, or must have submitted an application for IEM membership at the time of the proposal submission. Applicants who received IEM seed grant funding in previous years may re-apply with justification of outstanding progress in terms of successful external funding. Project Period: The project period is for a full calendar year of 2014. Proposals will be evaluated on the following criteria: 1. 2. 3. 4. 5. Scientific Strength Novelty Potential to Generate New External Funding Expertise of Investigators Strength of Collaboration between AHC and CSE Deadline: Applications are due by October 16, 2013 at 5:00 pm Questions and application submissions regarding any IEM grant program may be directed to: Adam Klein (klei0115@umn.edu), 612-624-8483. 1 IEM Exploratory Grant Application FY14 ≤ 1 page PI: Co-Is: Project Title: Summary of proposed research (no more than 250 words): Proposed Amount: Mailing Address: Phone: Email: PI Signature: (the PI may type the name below and e-mail the proposal from his/her UMN account) This is to confirm that if an award is granted by IEM, staff/administrative support will be provided by PI’s home department. Department Head Signature: (An e-mail from the Dept Head maybe attached with the proposal to serve as signature) 2 Objectives 0.5-1 page Describe the goals of the proposed project, including the key hypothesis and specific aims. 3 Background and Significance 1 page Explain the background of the science or technology leading to the proposal, and describe why this project is important and the potential impact or significance of the results. 4 Research Plan <=2 pages Describe study design and planned activities. Describe novelty. Describe nature of collaboration. Describe milestones and timeline for external grant submission. 5 Prior Funding Please list any previous funding that the PI and Co-Is have received from IEM (If applicable) Please list any results that you have gained from this previous funding, specifically: External Funding (agency, total amount, grant title, dates, your role) Peer Reviewed Journal Publications (title, authors, publication, pages, year) Invention Disclosures to UMN Patent Applications (note if awarded) 6 Additional Materials to Submit 1. References (no more than 1 page) 2. Current NIH-formatted biosketches for investigators, including other support information. 3. Detailed budget with justification for supplies, equipment, or research assistants a. $15,000-$25,000 b. Acceptable items include: graduate student / postdoc / tech support, materials and supplies, scientific services (e.g., flow cytometry, histology, imaging and MSI), other costs (including animal purchase and housing) and other personnel. 4. Matching funds, if available. Include letter from matching entity. Instructions for Submition: E-mail to iem@umn.edu with a single pdf file of the entire proposal. 7