UNIVERSITY OF TORONTO AT MISSISSAUGA DEPARTMENT OF PSYCHOLOGY SPRING 2007 PSY393H5 – Cognitive Neurology TUE 9am-12pm RM NE 172 Course Details Instructor Gary Turner Office Hours After class or by appointment Teaching Assistant Vedran Lovic Reading Materials Course Description: Evaluation: gary@psych.utoronto.ca vedran@psych.utoronto.ca Banich, M.T. (2004). Cognitive Neuroscience and Neuropsychology, 2nd edition. New York: Houghton Mifflin Company. This course will review major topics in cognitive neuroscience and neuropsychology with an emphasis on human cognitive function and dysfunction. Initial lectures will consist of a general introduction to neuroanatomy, cortical organization and methods used by cognitive neuroscientists. These will be followed by lectures focusing on specific areas of cognitive functioning and related disorders (e.g., attention and neglect; memory and amnesia; language and aphasia etc). Case reports will be used to illustrate key points and students will be required to examine the relationships between brain, behaviour and cognitive function using a case-based approach. Term Test 40% (February 13, 2007) Term Paper 20% (Due: March 20, 2007) Final Exam 40% (To be scheduled) Departmental Policies Missed Tests / Extensions Academic Guidelines Plagiarism Make-up tests will not be given in this course under any circumstance. All requests for adjusting the grading scheme for missed tests and for extended time to submit term work beyond the last day of classes must be completed on a special form obtained from the Psychology Office and submitted to the Undergraduate Assistant (RM2037B) within one week. If you submit medical documentation make sure it contains the statement "This student was unable to write the test (or submit term work by the last day of classes, if applicable) on (date) for medical reasons". You MUST see your physician on the day of the missed test or the day after the test or your request will be denied. For further information on this process visit http://www.utm.utoronto.ca/3104.0.html It is your responsibility to ensure that you have met all prerequisites listed in the UTM College Calendar for this course. If you lack any prerequisites for this course, the Department many cancel your registration at anytime. Further information about academic regulations, course withdrawal dates and credits can be found in the University of Toronto at Mississauga Calendar http://www.erin.utoronto.ca/regcal/ . You are encouraged to read this material. If you run into trouble and need information about studying, preparing for exams, note taking or time management, free workshops and advice are available from the Academic Skills Centre, which can be reached at 905-828-5406. Plagiarism is a serious offense. Students are expected to use the APA style for referencing, 5th edition. While you are encouraged to study with other students for exams that will be taken independently in class, the written work that you hand in for this class is expected to be your own. From the Code of Behaviour on Academic Matters: “It shall be an offence for a student to knowingly: represent as one's own any idea or expression of an idea or work of another in any academic examination or term test or in connection with any other form of academic work, i.e. to commit plagiarism. Wherever in the Code an offence is described as depending on "knowing," the offence shall likewise be deemed to have been committed if the person ought reasonably to have known” (http://www.utoronto.ca/writing/plagsep.html#100). All students must refer to this website to obtain information on what constitutes plagiarism. If questions arise after reading the material on the website, consult your instructor. Plagiarism will not be tolerated. Course Outline DATE January 09 January 16 TOPIC NOTES Introduction toCognitive Neuroscience & Neuropsychology (Approaches & Methods) Reading: - Chapter 3 pp.61-111 Brain Structure & Function – Cortical Specialization & Behavioural Neuroanatomy Term-Paper Tutorial January 23 January 30 The Agnosias (Disorders of Sensory Functioning) The Apraxias (Disorders of Motor Control) Readings: - Chapter 1: 3-39; Chapter 4: 112-123 - Mesulam, M.M. (1997). Anatomic Principles in Behavioral Neurology and Neuropsychology. In: M.J. Farah & Feinberg T.E. (Eds.) Behavioral Neurology and Neuropsychology. NY: McGraw-Hill pp. 55-68 Readings: - Chapter 6 pp. 184-220 - Ungerleider, L. G., & Haxby, J. V. (1994). ‘What and where’ in the human brain. Current Opinion in Neurobiology, 4(2), 157-165. Readings: - Chapter 5 pp. 145-183 - Heilman, K.M.; Watson, R.T.; Gonzalez-Rothi, L.J. (2006). Disorders of Skilled Movements: Limb Apraxia. In Farah, M.J. (Ed); Feinberg, T.E. (Ed). Patient-based approaches to cognitive neuroscience (2nd ed.). (pp. 341-348). Readings: - Chapter 10 pp. 322-364 - Rosenbaum, R.S., Kohler, S., Schacter, D.L., Moscovitch, M., Westmacott, R., Black, S.E., Cao, F., Tulving, E. (2005). The case of K.C.: contributions of a memory-impaired person to memory theory. Neuropsychologia, 43(7): 9891021. February 06 Amnesic Syndromes (Memory Disorders) February 13 (MID-TERM EXAM) Mid-Term Exam (2 hours) No readings February 20 (NO LECTURE) Reading Week No readings February 27 Aphasic Syndromes (Language Disorders) Readings: - Chapter 9 pp. 285-321 - Saygin AP, Dick F, W Wilson S, F Dronkers N, Bates E. (2003). Neural resources for processing language and environmental sounds: Evidence from aphasia. Brain 126 (4), pp. 928-45. March 06 March 13 March 20 (TERM PAPER DUE) March 27 Neglect Syndromes (Attention-based Disorders) Frontal Lobe Syndromes I (Goal Direction & Self Regulation) Frontal Lobe Syndromes II (Executive Cognition & Awareness) Affective Disorders (Depression & Neuropsychiatric Syndromes) April 02 Neuropathology and Neuroplasticity April 09 The Syndrome “Quiz” (Uncommon neurological syndromes) (PRE-EXAM REVIEW) Course Wrap-up & Pre-exam Review Readings: - Chapters 8 pp. 252-284. - Posner, M., & Petersen, S. (1990). The attention system of the human brain. Annual Review of Neuroscience, 13, 2542. Readings: - Chapter 11 pp. 365-392. - Mesulam, M. (2002). Human Frontal Lobes: Transcending the Default Mode Through Contingent Encoding. In: D.T. Stuss & R.T. Knight (Eds), Principles of Frontal Lobe Function. pp. 8-30. Readings: - Stuss, D. T., & Alexander, M. P. (2000). Executive functions and the frontal lobes: a conceptual view. Psychological Research, 63(3-4), 289-298. - D'Esposito, M., Cooney, J. W., Gazzaley, A., Gibbs, S. E., & Postle, B. R. (2006). Is the prefrontal cortex necessary for delay task performance? Evidence from lesion and FMRI data. Journal of the International Neuropsychological Society, 12(2), 248260. Readings: - Chapter 12 pp. 393-428. - Mayberg, H., Keightley, M., Mahurin, R. K., & Brannon, S.K. (2004). Neuropsychiatric Aspects of Mood and Affective Disorders. In Yudofsky, S.C.; Hales, R.E. (2004). Essentials of neuropsychiatry and clinical neurosciences. pp. 489-517. Readings: - Chapter 14 pp. 477-517. - Kolb, B. & Whishaw, I. Q. (2003). Fundamentals of Human Neuropsychology. 5th Edition. New York: Worth Publishers. Chapter 25, pp. 670696. Course Review. No readings assigned