Undurti N. Das, MD, FAMS
Undurti N. Das, MD, FAMS
UND Life Sciences
13800 Fairhill Road, #321
Shaker Heights, OH 44120
PROFESSIONAL GOALS:
To develop new anti-obesity, anti-cancer, anti-diabetic, anti-hypertensive, anti-infective, and antischizophrenia drugs; Investigate the role of long-chain polyunsaturated fatty acids in the prevention of adult
diseases including nephropathies that occur in diabetes, hypertension, collagen vascular diseases, depression,
and schizophrenia and to do clinical oriented research. To study the interactions between genes and
environment in these clinical conditions using microarrays and SiRNA techniques, and to develop newer
diagnostic markers for these clinical conditions.
RESEARCH:
 Over 25 years research experience
 Well versed with modern biological research techniques
 Extensive supervisory experience both at undergraduate and graduate level
 12 doctoral students obtained their Ph.D. in Biochemistry under my supervision
 Essential fatty acids, eicosanoids, cytokines, free radicals, nitric oxide, melatonin and their role in various
clinical conditions with special interest in angiogenesis and its role in cancer, free radicals and melatonin
in various disease processes including mutagenesis, carcinogenesis, cancer, diabetes mellitus, essential
hypertension, coronary heart disease, peptic ulcer disease and osteoporosis
CLINICAL SUMMARY:
 More than 20 years experience as a Professor of Internal Medicine, teaching graduates and specialist
candidates in Internal Medicine, Endocrinology, Rheumatology and Diabetology
 Extensive experience in patient care
 Management of diverse types of clinical conditions and clinical research and trials
 More than 20 years of clinical experience in the areas of Internal Medicine, Endocrinology, Diabetology
and Rheumatology, and oncology
HONORS AND AWARDS:
 Shakuntala Amirchand prize of ICMR in Experimental Medicine -1988
 Dr.Coelho Memorial Prize of Association Physicians of India in Experimental Medicine - 1992
 Regional Research Award of Japanese Society of Clinical chemists - 1992
 Elected as Fellow of the National Academy of Medical Sciences -1992
 Shanti Swaroop Bhatnagar prize in Medical Sciences -1992
 Elected as Fellow of the Indian College of Physicians (FICP) -1993
MEMBERSHIPS
Lifetime Member of:
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Association of Physicians of India
Indian Association for Cancer Research
Indian Society of Oncology
Indian Rheumatism Association
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National Council on Hypertension
International College of Nutrition
Diabetic Association of India
The Indian Society of Human Genetics
Indian Society of Critical Care Medicine
Association for the promotion of DNA fingerprinting and other DNA technologies
Indian Society of Parenteral and Enteral Nutrition
Society of Biological Chemists (India)
South Asian Society on Atherosclerosis and Thrombosis
Member of:
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New York Academy of Sciences, USA
American Association for the Advancement of Science
Society for Experimental Biology and Medicine, New York, USA
Member of the Editorial Board of the journals:
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Nutrition: published from N.Y., USA
Medical Science Monitor: published from Poland
Editor-in-Chief, Lipids in Health and Disease-published by BioMed Central, U.K.
XX vs XY: The International Journal of Sex Differences in the Study of Health, Disease and Agingpublished from Syracuse, NY, USA
Journal of the Association of Physicians of India
Current Nutrition and Food Science
The European Journal of General Medicine
Current Pharmaceutical Biotechnology
SELECTED PUBLICATIONS:
Over 300 publications in print.
1. Das UN. Pathophysiology of metabolic syndrome X and its links to the perinatal period.
Nutrition 2005; 21: 762-773.
2. Das UN. Long-chain polyunsaturated fatty acids, endothelial lipase, and atherosclerosis.
Prostaglandins Leukotrienes Essen Fatty Acids 2005; 72: 173-179.
3. Das UN. Is angiotensin II an endogenous pro-inflammatory molecule? Med Sci Monit
2005; 11: RA155-RA162.
4. Das UN. A defect in the activity of 6 and 5 desaturases may be a factor predisposing to
the development of insulin resistance syndrome. Prostaglandins Leukotrienes Essen Fatty
Acids 2005; 72: 343-350.
5. Das UN. COX-2 inhibitors and metabolism of essential fatty acids. Med Sci Monit 2005;
11: RA233-RA237.
6. Das UN. Essential fatty acids and acquired immunodeficiency syndrome. Med Sci Monit
2005; 11: RA 206-RA211.
7. Das UN. Angiotensin-II behaves as an endogenous pro-inflammatory molecule. J Assoc
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Physicians India 2005; 53: 472-476.
8. Das UN. Can COX-2 inhibitors-induced increase in cardiovascular disease risk be
modified by essential fatty acids? J Assoc Physicians India 2005; 53: 623-627.
9. Das UN. Long-chain polyunsaturated fatty acids and metabolic syndrome X. In:
Nutrients, Stress and Medical Disorders, Eds. Yehuda S and Mostofsky DI, Humana
Press Inc., Totowa, NJ, USA, 2005, pp. 315-322.
10. Das UN. Nutritional factors in the prevention and treatment of cardiovascular diseases.
In: Functional Foods for Cardiovascular Diseases, Ed. Danik M. Martirosyan, D & A
Inc., Richardson, TX, USA, 2005, pp. 31-45.
11. Das UN. A radical view of hypertension. In: Biomedical significance of nitric oxide, Ed
Stefano GB, Medical Science International Co. Ltd., Warsaw-New York, 2003, pp. 243263.
12. Das UN. Can free radicals induce coronary vasospasm and acute myocardial infarction?
Med Hypotheses 1992; 39: 90-94.
13. Das UN. Clinical laboratory tools to diagnose inflammation. Adv Clin Chemistry 2006;
41: 189-229.
14. Sailaja MMS, Das UN. Effect of prostaglandins against alloxan-induced diabetes
mellitus. Prostaglandins Leukot Essen Fatty Acids 2006; 74: 39-60.
15. Das UN. Lipids in cancer with particular reference to gamma-linolenic acid. In: Frontiers
16. in Functional Lipids, eds. Sato K, Yanagita T, Wada S, 2004.
17. Das UN. Can critical illness and sepsis be predicted or prognosticated? Adv Sepsis 2006;
5: 52–59.
18. Das UN. Do unsaturated fatty acids function as endogenous anti-bacterial and anti-viral
molecules? Am J Clin Nutr 2006; 83: 390-391.
19. Das UN. A perinatal strategy to prevent adult diseases. 2nd International Symposium on
Functional Foods for the Prevention and Treatment of Chronic Diseases. November 1516, 2005, Dallas, Texas, USA.
20. Das UN. Gamma-linolenic acid and its derivatives as potential tumoricidal and antiangiogenic drugs for cancer. APICON-2006, Patna, India.
21. Suresh Y and Das UN. Differential effect of saturated, monounsaturated, and
polyunsaturated fatty acids on alloxan-induced diabetes mellitus. Prostaglandins Leukot
Essen Fatty Acids 2006; 74:199-213.
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22. Das UN, Rao KP. Effect of γ-linolenic acid and prostaglandins E1 on gamma-radiation
and chemical-induced genetic damage to the bone marrow cells of mice. Prostaglandins
Leukot Essen Fatty Acids 2006; 74:165-173.
23. Das UN. Exercise and inflammation. Eur Heart J 2006; 27: 1385-1386.
24. Das UN. Hypertension as a low-grade systemic inflammatory condition that has its
origins in the perinatal period. J Assoc Physicians India 2006; 54: 133-142.
25. Das UN. Essential fatty acids: Biochemistry, physiology, and pathology. Biotechnology J
26. 2006; 1: 420-439.
27. Das UN. Pyruvate is an endogenous anti-inflammatory and anti-oxidant molecule. Med
Sci Monit 2006; 12: RA79-RA84.
28. Das UN. Biological significance of essential fatty acids. J Assoc Physicians India 2006;
54: 309-319.
29. Das UN. Can perinatal supplementation of long-chain polyunsaturated fatty acids prevent
atopy, bronchial asthma and other inflammatory conditions? Med Sci Monit 2006; 12:
RA99-RA111.
30. Das UN. Is pyruvate an endogenous anti-inflammatory molecule? Nutrition 2006; 22:
965-972.
31. Das UN. Aberrant expression of perilipins and 11-β-HSD-1 as molecular signatures of
metabolic syndrome X in South East Asians. J Assoc Physicians India 2006; 54: 637649.
32. Das UN. Glucose, insulin, and coronary heart disease. Eur Heart J 2006; 27: 2141-2142.
33. Das UN. Fetal alcohol syndrome and essential fatty acids PLoS Med 2006; 3: e247.
34. Das UN. Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu
(erbB-2) oncogene. J Natl Cancer Inst 2006; 98: 718.
35. Zampelas A, Panagiotakos DB, Pitsavos C, Das UN, Chrysohoou C, Skoumas Y,
Stefanadis C. Fish consumption among healthy adults is associated with decreased levels
of inflammatory markers related to cardiovascular disease: the ATTICA study. J Am
Coll Cardiol 2005; 46:120-124.
BOOKS:
1. Das UN. A Perinatal Strategy for Preventing Adult Diseases: The Role of Long-chain
Polyunsaturated Fatty Acids. Kluwer Academic Publishers, Boston, 2002.
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