Varicose Veins in the legs: NICE podcast transcript Hello and welcome to this podcast on the NICE clinical guideline on varicose veins in the legs. This podcast is aimed at commissioners and summarises the main changes in practice outlined in the guideline and the cost benefits of implementing these changes. I’m at Charing Cross Hospital with Professor Alun Davies, Professor of Vascular Surgery at Imperial College London and Honorary Consultant Surgeon at Imperial College NHS Trust, Charing Cross and St Mary’s Hospitals. Professor Davies was also chair of the group that helped develop the guideline. Q1: “Professor Davies, among the guideline’s recommendations are the circumstances when patients should be referred to a vascular service. What does NICE recommend and what change in practice will this lead to?” AD: “NICE recommends that all patients with symptomatic varicose veins, be they primary or secondary, should be referred to a vascular service. The classic symptoms are of aching, itching, swelling in the legs. The guideline also recommend that those patients suffering from complications, be that bleeding, thrombophlebitis and venous leg ulceration should be referred for a vascular service for evaluation and then advice with respect to subsequent treatment. A group of patients who have skin changes ought to be referred also to a vascular service.” Q2: “And what are the clinical benefits of this recommendation?” AD: “Clinical benefits are that a large number of patients at present are not being offered intervention for their symptoms of varicose veins. Patients with the varicose veins, as I’ve highlighted, have symptoms of aching, itching, pain, discomfort and swelling. It is also known that patients have a significantly worse quality of life compared to their age related rest of the population. And it has been shown that various interventions on patients’ varicose veins will enable their quality of life to return to normal.” Q3: “And what are the likely cost benefits of implementing this recommendation?” AD: “Compared to the amount spent on varicose veins in 2013 the estimate is that there will have to be an increase in expenditure of approximately 25 per cent of budget. However, it should be noted that in the preceding four years, secondary to a postcode lottery and restrictions, we have seen a reduction in the number of patients having intervention by at least 30 per cent. So that compared to figures in 2004/2005 we will be returning to that level of offering intervention. The overall cost impact is thought to be around about £9,000 per 100,000 of the population.” Q4: “The guideline recommends a sequence of interventional procedures for people with confirmed cases of varicose veins. What is the sequence and why is it ordered as such?” AD: “The sequence for the interventional treatment for varicose veins has been predicated on the cost effectiveness of the intervention and has been based on a cost effective model. There is a large heterogeneity in patients who present with varicose veins but for a ”standard patient” who has great saphenous vein incompetence with tributaries the hierarchy for intervention is endothermal ablation. If this is not suitable or declined then it is foam sclerotherapy with surgery being the third option. There is the other recommendation that compression hosiery should only be offered to patients in whom the other interventional treatments are not suitable or are actually declined by the patient.” Q5: “And are there any particular clinical benefits of endothermal ablation?” AD: “The overall clinical benefit is that the patient in this instance does not need to have a general anaesthetic and can usually return to work within a day or two.” Q6: “And what does NICE say the cost benefits are of this sequence?” AD: “Well, undoubtedly if you look at the economic modelling there is significant benefit in offering endothermal ablation before foam and foam before surgery. Overall it is cheaper to offer endothermal ablation than surgery. And with the change in the availability of endothermal ablation around the country this should actually result in an overall reduction in the overall cost. And with an increase of endothermal ablation up to about 70 per cent there will be probably an overall £8,400 saving per annum per 100,000 of the population. Therefore looking at the previous figure it would suggest that overall this would only be a cost pressure of £600 per 100,000 of the population per year. Q7: “Compression hosiery is widely used as a first line treatment for varicose veins yet the guideline says that this should only be offered if interventional treatment is suitable. Why does NICE say this?” AD: “NICE has come up with this recommendation as many patients were being denied interventional therapy because it was thought that compression hosiery was sufficient to treat their symptoms and this was being delivered in primary care. The NICE guideline have shown very clearly that the interventional treatments, such as endothermal ablation, foam sclerotherapy and surgery, actually improve patients’ quality of life significantly more than offering the compression hosiery. And the recommendation is such to ensure that all patients are assessed properly and are evaluated for what is the best and most cost effective intervention. It should be noted that if you are recommending somebody wears compression hosiery you are giving them that as a recommendation for the rest of their life and that has an annual cost of at least £182 per annum. So overall you can see that there is undoubtedly a cost benefit and also there is a much more effective treatment by offering them more interventional therapies.” Q8: “What would you say is the current level of care of varicose veins in this country?” AD: “There is undoubtedly a postcode lottery. And in 2012 this was identified using HES data to be at least a tenfold difference depending on your location. Furthermore, there was also a significant difference in the treatment options made available in the NHS. In some areas only surgery was available or foam sclerotherapy. And it is hoped that this guideline will ensure that all patients are offered the most suitable modality for treatment of their varicose veins, and, as you have heard previously, most people should be offered endothermal ablation. It is also hoped that having worked with the commissioning groups at the Royal College of Surgeons that the commissioners will be informed by the NICE guideline so that they will purchase care at an appropriate level to ensure that all patients in this country get an equal chance of having the appropriate treatment for their varicose veins. Professor Davies, thank you very much. 20 February 2014