BRITISH SOCIETY OF GASTROENTEROLOGY
ANNUAL SCIENTIFIC MEETING
26-29 MARCH 2007 : GLASGOW
Monday 26 March
09.30-17.00
09.30
09.50
10.10
10.30
10.50
11.10
11.30
11.55
12.15
12.40
13.00
14.00
14.45
15.15
15.30
15.50
16.10
16.35
17.00
POSTGRADUATE COURSE : ‘Modern gastrointestinal
Endoscopy : Looking at and below the surface’ : Clyde Theatre :
Chair – Professor AI Morris and Professor FKL Chan (am); Dr A Cole
and Dr I Penman (pm)
Treatment of upper gastrointestinal bleeding (with video clips)
Modern endoscopic treatment of non-variceal upper gastrointestinal
bleeding (Dr KR Palmer, Edinburgh)
Modern treatment of variceal bleeding
(Professor AK Burroughs, London)
Discussion
Diagnosisis of gastrointestinal neoplasia and pre-neoplasia – new
endoscopic techniques
Magnification and chromo-endoscopy (Dr DP Hurlstone, Sheffield)
Narrow band, auto-fluorescence and confocal Endoscopy
(Dr ID Penman, Edinburgh)
Discussion
Coffee
Recently established methodologies (I)
Capsule Endoscopy : practical uses and complications
(Dr M McAlindon, Sheffield)
Enteroscopy – is double balloon an advantage?
(Dr AJ Morris, Glasgow)
Discussion
Lunch (+ launch of E-based Lesion Recognition System) – Professor
AI Morris
Debate : ‘This house supports the BSG Guidelines on surveillance of
Barrett’s oesophagus’
For :
Mr R Stuart, Glasgow
Against : Professor RJ Playford, London
Recently established methodologies (II)
Endoscopic ultrasound : what are its proven benefits
(Dr A Cole, Derby)
Discussion
Tea
Training and Service in the future
Training and certification for the new techniques – a new model
needed? (Dr JRB Green, Stoke on Trent)
Modern endoscopic services and standards (including implications of a
national colon cancer screening programme for endoscopy services)
(Dr R Valori, Gloucester)
The role/s of the gastrointestinal endoscopist in the future
(Professor AI Morris, Liverpool)
End
Monday 26 March
17.30-19.30
Trainees in Gastroenterology – ‘MMC : the end of
gastroenterology as we know it’ Clyde Theatre– Chair – Dr Robert
Logan
Introduction (Professor Roger Barton, JAG Chairman)
Debate : ‘this House believes that Modernising Medical Careers is the
end of gastroenterology as we know it’
For : Dr J Green, Llandough
Against : Dr A McIntyre, Manpower Co-Ordinator, RCP
Tigs AGM
This session is generously sponsored by Procter and Gamble
Pharmaceuticals
2
Tuesday 27 March
07:30 – 08.45
‘Question the Expert’ Breakfast Meeting – The Castle Suite of the Crowne Plaza Hotel
(adjacent to SECC)
‘Endoscopic mucosal resection; when I do, what I do and when I don’t’
(Dr BJ Rembacken, Leeds)
08.30-12.00
08.30-08.50
08.50-09.10
09.10-09.30
09.30-09.50
09.50-10.05
O-001
10.05-10.20
O-002
10.20-10.50
10.50-12.00
10.50-11.10
11.10-11.20
11.20-12.00
INFLAMMATORY BOWEL DISEASE : ‘Using
immunomodulation wisely’ : Clyde Theatre : Chair – Dr S Bloom and
Dr J Satsangi
Azathioprine – New perspectives (Professor M Neurath, Mainz)
Safety of biological therapies – trick or TREAT!
(Professor J-F Colombel, Lille)
Anti-TNF therapy – Lessons from rheumatology
(Dr D Isenberg, London)
An alternative perspective – defective innate immunity and the use of
GM-CSF (Dr S Bloom, London)
The use of adalimumab in refractory Crohn’s disease: a tertiary referral
centre experience (G Ho, L Smith, S Aitken, J Rose,
B Ruddell,P Bramley, K Palmer, I Arnott, A Shand, J Satsangi)
Infliximab as rescue therapy in acute severe UC: a survey of the
Scottish Society of Gastroenterology (SSG). (CW Lees, D Heys,
AG Shand, ID Penman, KR Palmer, C Mowat, H Jafferbhoy,
R Boulton-Jones, A Williams, H Gillett, C Evans, J Todd, N Church,
K Vaidya, J Rose, IDR Arnott, J Satsangi)
Coffee
Chair : Dr R Cowen and Dr J Satsangi
Update on National IBD Audit (Dr K Leiper, Liverpool)
Case presentation (Dr IDR Arnott, Edinburgh)
Debate : second-line medical therapy in acute severe ulcerative colitis
– saving colons, or risking lives?
Motion : Colectomy is the treatment of choice in acute severe colitis
resistant to first-line medical therapy.
For : Mr AI Windsor (London)
Against : Professor M Kamm (London)
12.05
Clyde Theatre : STATE-OF-ART LECTURE :
‘Optimising growth in early-onset inflammatory bowel disease’
(Professor Anne Griffiths, Toronto)
Chair : Dr S Bloom
09.00-12.00
LIVER FREE PAPERS : Lomond Theatre : Chair – Dr J Freeman
and Dr S Ryder
A comparison of scoring systems for organ allocation on the liver
transplant waiting list (MR Foxton, P Muiesan, N Heaton, J O'Grady,
M Heneghan)
1 year survival in Budd Chiari syndrome treated with TIPS – an
international study (M Heydtmann, S Raffa, S Olliff, A Plessier,
T Luong, F Fabris, A Luca, J Abraldes, G. Vizzini, M Primgnani,
S Murad, D Valla, E Elias, J Garcia)
09.00-09.15
O-003
09.15-09.30
O-004
3
09.30-09.45
O-005
09.45-10.00
O-006
10.00-10.15
O-007
10.15-10.45
10.45-11.00
O-008
11.00-11.15
O-009
11.15-11.30
O-010
11.30-11.45
O-011
11.45-12.00
O-012
Ischemia-reperfusion injury promotes hematopoietic stem cell
recruitment to the murine hepatic microcirculation in vivo
(DPJ Kavanagh, PF Lalor, DH Adams, J Frampton, N Kalia)
Reprioritisation of liver export protein synthesis in patients with
decompensated alcoholic liver disease (R Hamid, DC McMillan,
T Preston, C Slater, N Joshi, A Stanley)
Prognostic factors in biliary tract carcinoma: multivariate analysis of
259 patients (WR Matull, L Ayaru, A Dias, D Dhar, BR Davidson,
SP Pereira)
Coffee
Hepatitis E in Southwest England (HR Dalton, W Stableforth,
U Warshow, P Thurairajah, S Hazeldine, R Ramnarace,
C Sieberhagen, J Mitchell, M Banks, S Ijaz, R Bendall)
Are MUC4 and/or MUC5AC useful tumour markers for biliary tract
cancer (BTC)? (WR Matull, A Loh, F Andreola, Z Adiguzel,
M Deheragoda, U Qureshi, DM. Swallow, SP Pereira)
A novel simple noninvasive test for the prediction of cirrhosis in
chronic hepatitis C: a validation and comparison of 707 patients
(TJ Cross, P Rizzi, M Bruce, P Berry, B Portmann, PM Harrison)
TIPSS in treatment of refractory ascites – a single centre experience
(N Kochar, D Tripathi, H Ireland, DN Redhead, PC Hayes)
Histological predictors of oesophageal varices. a single blinded
retrospective analysis (T Thomas, S Menon, G Mortimer,
D Semeraro, V Lai, AS Austin, J Freeman)
GASTRODUODENAL/ENDOSCOPY SYMPOSIUM : ‘Acute
Upper GI Haemorrhage’ : Hall 1 : Chair – Professor EM El-Omar
and Dr JRB Green
Risk assessment in UGIT bleeding (Dr H Dalton, Truro)
Management of UGIT bleeding – Practical aspects
(a) It’s Friday afternoon and Mrs Good, a fit 86 year old on
NSAIDs for mild osteoarthritis has a haematemesis
(Professor F Chan, Hong Kong)
(b) Few days later she rebleeds … (Mr G Fullarton, Glasgow)
(c) Later that day Mr Bad, a 58 year old diabetic with an aortic valve
replacement, on warfarin, also has a haematemesis
(Professor AI Morris, Liverpool)
It’s Thursday night and Mr Ugly, a 76 year old presents with melaena
… (Dr M Allison, Newport)
Coffee
BSG audit on upper GI bleeding (Dr KR Palmer, Edinburgh)
Service provision for haematemesis – bleeding the NHS dry?
(Dr IG Barrison, St Albans)
09.00-12.00
09.00-09.30
09.30-10.30
09.30-09.45
09.45-10.00
10.00-10.15
10.15-10.30
10.30-11.00
11.00-11.30
11.30-12.00
09.00-10.15
09.00-09.15
O-013
09.15-09.30
O-014
PATHOLOGY FREE PAPERS : Dochart Theatre : Chair – Professor
M Pignatelli and Dr J Crabtree
A retrospective analysis of GIST mutation status in one UK reference
centre (B O'Sullivan, NS Deshmukh, GM Reynolds, I Geh,
P Taniere)
The characterisation of bacterial community diversity in cultures
4
09.30-09.45
O-015
09.45-10.00
O-016
10.00-10.15
O-017
10.15-10.45
10.45-12.00
10.45-11.00
O-018
11.00-11.15
O-019
11.15-11.30
O-020
11.30-11.45
O-021
11.45-12.00
O-022
INFORMATION TECHNOLOGY SYMPOSIUM : ‘What will the
billions spent on NHS IT do for me?’ : Leven Theatre : Chair – Dr T
Heymann
Introduction to NHS CfH (Dr Ian Scott, Ipswich)
CaB (how do patients get to us) (Dr Robert Logan, Nottingham)
NLH (how do we look after them) (Dr M Caplin, London)
PbR (how do we get paid for what we do) (Dr J Ramage, Basingstoke)
Panel Discussionand Q&A
10.30-12.00
10.30-10.45
10.45-11.00
11.00-11.15
11.15-11.00
11.30-12.00
09.00-12.00
09.00-09.15
derived from healthy and inflamed ileal pouches after restorative
procto-colectomy, using 16S ribosomal DNA terminal restriction
fragment length polymorphism (T-RFLP) profiling (MW Johnson,
GB Rogers, S Mclaughlin, KD Bruce, A Forbes, PJ Ciclitira,
JR Nicholls)
Stromal gene expression may be responsible for mantaining
morpholgical differences between small and large bowel (J Murphy,
S Khalaf, RE Hands, CLH Chan, SA Bustin, NS Williams)
The expression pattern of MCMs, geminin and their relationship to
tumour differentiation and patient survival differs between gastric and
small bowel adenocarcinoma (R Sekhon, J Knock, M Shah, K Maude,
G Williams, P Howdle, P Quirke, R Watkins, H Grabsch)
The Apc1310T/+ mouse: a novel murine model of intestinal
tumorigenesis analogous to the APC-1309 mutation causing severe
intestinal polyposis in humans (MG Deheragoda, P Pollard, E Nye,
P Seedhar, N Mandir, R Jeffery, NA Wright, I Tomlinson)
Coffee
ENDOSCOPY FREE PAPERS : Dochart Theatre :
Chair – Dr R Tighe and Dr H Shepherd
The impact of colorectal cancer family history clinic on yield of
colonoscopic screening (B Desouza, T Elliott, I Rowe, M Smith,
F Hibberts, C Coughland, A Sadoo, S Levene, G Scott, L Izatt,
J Sanderson)
Early experience of the multibander endosocpic mucosal resection
(EMR)- benefits and short comings. (SK Enaganti, S Sonwalkar,
L Smith, BJ Rembacken)
What are the sensitivity and specificity of endoscopic photographs in
documenting completion of colonoscopy? results from an online
questionnaire. (AI Thuraisingam, JL Brown, JT Anderson)
Botox predicts the outcome of endoscopic sphincterotomy in postcholecystectomy biliary pain due to sphincter of Oddi spasm
(SC Kong, ZCJ Higgs, WR Murray)
Determination of safety of drinking before gastroscopy (L Miller,
P Dey, D Lynch, G Banait, A Fergusson, H McMurtry, E Barnes,
P Carr)
O-023
OESOPHAGEAL FREE PAPERS : Alsh Theatre :
Chair – Mr T Dehn and Dr S Riley
Large-scale prospective study reveals novel risk factors for Barrett’s
oesophagus (A Wong, L Lovat, RW Burnham, A Hackshaw,
R Fitzgerald)
5
09.15-09.30
O-024
09.30-09.45
O-025
09.45-10.00
O-026
10.00-10.15
O-027
10.15-10.45
10.45-11.00
O-028
11.00-11.15
O-029
11.15-11.30
O-030
11.30-11.45
O-031
11.45-12.00
O-032
09.00-12.00
09.00-09.30
09.30-10.00
10.00-10.30
10.30-10.45
10.45-11.30
11.30-12.00
09.00-10.30
09.00-09.15
09.15-09.30
Mapping clonality in individual glands from human Barrett's
oesophagus (SJ Leedham, S Macdonald, D Poller, R Harrison,
J Jankowski, N Wright)
Low incidence of oesophageal adenocarcinoma following optimal
regimen of ALA PDT for high grade dysplasia in Barrett’s oesophagus
(GD Mackenzie, CR Selvasekar, N Jamieson, CA Mosse, SM Thorpe,
MR Novelli, SG Bown, LB Lovat)
Interobserver variation in the diagnosis of dysplasia in Barrett's
oesophagus (SA Sonwalkar, O Rotimi, N Scott, M Dixon, A Axon,
SM Everett)
Dynamics of unbuffered postprandial acid pocket and role in acidic
gastroesophageal reflux (AT Clarke, AA Wirz, JP Seenan,
JJ Manning, D Gillen, KEL McColl)
Coffee
The prevalence of laryngopharyngeal reflux in a population with
gastro-oesophageal reflux. (M Groome, JP Cotton, M Borland,
S McLeod, JF Dillon)
Laser and radical chemoradiotherapy for oesophageal carcinoma
(PM Irving, A Hart, S Thorpe, G Blackman, SG Bown, J Tobias,
LB Lovat)
Clinical outcome of cases with indefinite for dysplasia in Barrett's
oesophagus over a twenty year period (SA Sonwalkar, O Rotimi,
N Scott, M Dixon, A Axon, SM Everett)
The SAINT trial (stem cell analysis and identification by IUdR
labelling of neoplastic tissue); identification of Barrett’s stem cells
(L Harrison, AM Nicholson, R Harrison, S McDonald, G Wilson,
PA Atherfold, N Wright, JA Jankowski)
Elastic scattering spectroscopy to generate an image of patient risk in
Barrett’s oesophagus. (GD Mackenzie, M Yong, B Clark,
MR Novelli, SM Thorpe, SG Bown, LB Lovat)
SURGERY/NUTRITION/AUGIS SYMPOSIUM : ‘Nutrition in the
Surgical Patient’ : Boisdale Theatre : Chair – Mr KR Wedgwood and
Mr GM Fullarton
Pre-operative nutrition and assessment of needs
(Ms RF McKee, Glasgow)
Nutritional aspects of oesophago-gastric surgery
(Professor SM Griffin, Newcastle upon Tyne)
Nutrition management in Crohn’s disease (fistulae)
(Mr AI Windsor, London)
Coffee
Nutrition in pancreatic disease and enhanced recovery after surgery
(ERAS) (Professor K Fearn, Edinburgh)
Postoperative nutrition (Dr TE Bowling, Nottingham)
TEAM WORKING AND THE INDIVIDUALISTIC
COLLEAGUE ‘Maverick or Top Gun’: Carron Theatre: Chair –
Professor AI Morris and Dr R Valori
Overview of maverick behaviour (Professor AI Morris)
The challenges that face mavericks (Professor J Brown)
6
The good,the bad and the ugly (Dr R Valori)
How to get the best out of a maverick (Professor John Rhodes)
How to manage mavericks – dealing with difficult colleagues,
incompetence and whistle blowing (Dr M Lombard)
Discussion
09.30-09.45
09.45-10.00
10.00-10.15
10.15-10.30
BSG/BASL SYMPOSIUM : ‘Hepatocellular carcinoma and
cholangiocarcinoma update’ : Clyde Theatre : Chair –
Professor AK Burroughs and Professor J Neuberger
Epidemiology of liver tumours (Dr M Toledano, London)
Imaging and staging (Dr A Lim, London)
Tumour surveillance (Dr J Bates, Leeds)
Non-surgical therapy of cholangiocarcinoma (Dr S Pereira, London)
Tea
Pharmacological interventions in HCC
(Professor P Johnson, Birmingham)
Percutaneous ablation of HCC (Dr S Ryder, Nottingham)
Transarterial ablation of HCC (Dr N Davies, London)
Surgery for HCC (Professor B Davidson, London)
14.00-17.00
14.00-14.20
14.20-14.40
14.40-15.00
15.00-15.20
15.20-16.00
16.00-16.15
16.15-16.30
16.30-16.45
16.45-17.00
17.05
SHEILA SHERLOCK LECTURE : Clyde Theatre :
‘Primary biliary cirrhosis 2007’
Professor OFW James, Newcastle upon Tyne
14.00-14.30
ENDOSCOPY FOUNDATION LECTURE : Lomond Theatre :
‘Optimising safety in endoscopy’
Professor GD Bell, Norwich
14.30-17.00
ENDOSCOPY FREE PAPERS : Lomond Theatre :
Chair – Dr M Allison and Dr A Veitch
Randomised controlled trial of patient controlled sedation for
colonoscopy: Entonox versus patient maintained target controlled
Propofol (S Maslekar, P Balaji, A Suppiah, JE Hartley, B Culbert,
GS Duthie)
High proficiency reading of 3D virtual colonoscopy by experienced
optical endoscopists and endoscopy nurses; a new era in colonoscopy?
(AB Patrick, L Jackson, S Edwards, J Bell, O Epstein)
Endoscopic mucosal resection for flat neoplasia in chronic ulcerative
colitis: can we change the endoscopic management paradigm?
(DP Hurlstone, DS Sanders, ME McAlindon, AJ Lobo, M Thomson,
R Atkinson, SS Cross)
Mortality following percutaneous endoscopic gastrostomy: results of
the national confidential enquiry into patient outcome and death
(SD Johnston, TCK Tham, M Mason)
Tea
Electronic chromoendoscopy in Barrett’s oesophagus using narrow
band imaging: a study to validate mucosal morphology findings and
inter /intra observer agreement. (R Singh, GK Anagnostopulos,
14.30-14.45
O-033
14.45-15.00
O-034
15.00-15.15
O-035
15.15-15.30
O-036
15.30-16.00
16.00-16.15
O-037
7
16.15-16.30
O-038
16.30-16.45
O-039
16.45-17.00
O-040
O-041
O-042
14.00-17.00
14.00-14.15
O-043
14.15-14.30
O-044
14.30-14.45
O-045
14.45-15.00
O-046
15.00-15.15
O-047
15.15-15.45
15.4516.00
O-048
16.00-16.15
O-049
16.15-16.30
O-050
16.30-16.45
O-051
16.45-17.00
O-052
K Yao, H Karageorgiou, P Fortun, A Shonde, K Garsed, P Kaye,
CJ Hawkey, K Ragunath)
Achieving R0 resection in the colorectum using endoscopic submucosal
dissection: first feasibility study in the United Kingdom.
(DP Hurlstone, R Atkinson, DS Sanders, SS Cross, SR Brown)
Randomised trial of narrow band imaging (NBI) for adenoma detection
at colonoscopy in high risk groups (JE East, N Suzuki,
M Stavrinidis, N Palmer, T Guenther, BP Saunders)
Study of serum electrolytes following sodium phosphate bowel
preparation and colonoscopy in patients with normal creatinine
(B Rameh, D Lamb, J Ramesh, S Balakrishnan, P Conlong, A Tawil)
Diagnosis of pancreaticobiliary malignancy by detection of
minichromosome maintenance 5 protein in bile aspirates (L Ayaru,
K Stoeber, GJ Webster, AR Hatfield, GH Williams, SP Pereira)
Narrow band imaging (NBI) for colonoscopic surveillance in hereditary
non-polyposis colorectal cancer (HNPCC) (JE East,
M Stavrinidis,N Suzuki, N Palmer, T Guenther, HJW Thomas,
BP Saunders)
SERVICE DEVELOPMENT FREE PAPERS : Hall 1 :
Chair – Dr R Valori
How to achieve an ‘A’ in timeliness: capacity and demand management
in endoscopy services (R Kasturi, E Said, S Pearson,
A Reddy, J Singh, A Saeed)
One week rapid improvement of quality and throughput in endoscopy
(L Hodgson, G Nicholson, H Gray, S More, J Stacey, C Jenkins,
K Oppong)
Global Rating Scale requirements for patient comfort in endoscopy – a
solution
(R Miskimmin, M Miskimmin, MD Rutter)
New Global Rating Scale shareware: endoscopy audit at a keystroke
(MS Smith, IP Crane, LM Atkin)
Effect of Helicobacter pylori eradication on dyspepsia, quality of life
and utilisation of healthcare resources in the Eastern England
Helicobacter pylori project: randomised controlled trial (C Osonnaya,
K Osonnaya, M Abdi, L Guo, S Smith)
Tea
Endoscopy 30 day mortality: a retrospective audit of diagnostic and
therapeutic endoscopy at a single unit (T Elliott, A Bales, T Wong,
J Sanderson, M McCarthy)
Colonoscopy waiting lists: revalidation by general practitioners is cost
effective and reduces unnecessary endoscopy commissioning
(PF Marden, A Newton, M Williamson, D Robertson)
An audit to understand outcomes of critcally ill gastroenterology
patients and the selection criteria used by critical care to improve
services (K Bowering, P Kelly, J McDonough, S Sarkar)
Towards a better outpatient service in IBD (A Malik, A Saeed,
S Bradbury, DW Bullimore)
Development of an endoscopic ultrasound (EUS)-guided fine needle
aspiration (FNA) cytology service – a review (SS Menon,
SA Kapadia, K Maleki, T Hollingsworth, NC Fisher)
8
RADIOLOGY/BSGAR SYMPOSIUM : ‘Current status of small
bowel investigation’ : Carron Theatre : Chair – Dr SH Lee
Small bowel barium studies (Professor C Bartram, London)
CT of the small bowel (Dr A Phillips, Bath)
Ultrasound of the small bowel (Dr A Higginson, Portsmouth)
Tea
MR of the small bowel (Professor T Fork, Malmo)
Capsule Endoscopy and small bowel entroscopy
(Dr D Sanders, Sheffield)
Discussion
14.00-16.30
14.00-14.20
14.20-14.40
14.40-15.00
15.00-15.15
15.15-15.45
15.45-16.15
16.15-16.30
14.00-17.00
14.00-14.15
O-053
14.15-14.30
O-054
14.30-14.45
O-055
14.45-15.00
O-056
15.00-15.15
O-057
15.15-15.45
14.00-17.00
14.00-14.30
14.30-15.00
15.00-15.30
15.30-15.45
15.45-16.15
16.15-17.00
14.00-17.00
14.00-14.30
NEUROGASTROENTEROLOGY/MOTILITY FREE PAPERS :
Dochart Theatre : Chair – Professor Q Aziz and Dr L Houghton
Isolation, characterisation and transplantation of human enteric nervous
system stem cells (C Caldwell, A Burns, N Thapar)
IBS shows an activated and effective immune system (EB Campbell,
K Garsed, M Richards, S Foley, M Hastings, P Whorwell,
Y Mahida, I Hall, K Neal, R Spiller)
Increased TRPV1 expressing nerve fibres in colonic biopsies from IBS
patients correlate with the degree of abdominal pain (A Akbar,
Y Yiangou, P Facer, P Anand, S Ghosh)
Functional evidence for hemispheric asymmetry in the cortical control
of human swallowing: a ‘virtual brain lesion’ study (S Mistry,
E Verin, S Singh, S Jefferson, J Rothwell, S Hamdy)
Normal rectal sensory function: evaluation using four different
modalities in healthy volunteers (SP Vasudevan, PJ Lunniss,
SM Scott)
Tea
PRIMARY CARE SOCIETY FOR GASTROENTEROLOGY :
Alsh Theatre : Chair – Dr R Stevens and Dr J Galloway
Dyspepsia in primary care : Interim report on a prospective study of
prognosis and outcome (Dr J Dalrymple, Secretary, PCSG, Norwich)
Bile acid malabsorption (BAM) (Professor KD Bardhan, Rotherham)
Caring for IBDE patients in the new NHS – Can shared care work? (Dr
S Bloom, London)
Tea
Bile and pepsin – How relevant in GORD
(Professor P Hungin, Durham)
How can primary and secondary care work together to tackle alcohol
abuse? (Professor I Gilmore, President, RCP London, and Liverpool)
GASTRODUODENAL SECTION SYMPOSIUM : ‘NSAIDs – the
Good, the Bad and the Ugly’ : Boisdale Theatre : Chair – Professor
EM El-Omar and Dr M Pritchard
Adverse effects of NSAIDs throughout the gut and elsewhere
(Professor I Bjarnasson, London)
9
14.30-15.00
15.00-15.30
15.30-16.00
16.00-16.30
16.30-17.00
14.00-17.00
14.00-14.15
14.15-14.45
14.45-15.30
15.30-16.00
16.00-16.30
16.30-16.45
16.45-17.00
Adverse effects of low dose aspirin and anti-thrombotic therapies
(Dr A Lanas , Spain)
Is Helicobacter pylori relevant in NSAIDs damage?
(Professor F Chan, Hong Kong)
Tea
Strategies for prevention of NSAIDs side effects
(Professor CJ Hawkey, Nottingham)
Do NSAIDs really prevent cancer?
(Professor RFA Logan, Nottingham)
NATIONAL INTEGRATED ACADEMIC TRAINING
PROGRAMME IN GASTROENTEROLOGY : Leven Theatre :
Chair – Professor DG Thompson
Chairman’s Introduction : Integrated academic training programme
update
Academic clinical fellows and lecturers : progress so far and plans for
the future (Dr Lisa Cotterill, DH Research Capacity Development
Program Leads for UKCRC Academic Career Development)
The Gastroenterology Training Curriculum and the academic trainee –
How the BSG can help? (Dr J Gibson, Chairman, SAC;
Dr M Lombard, Chairman, BSG Training Committee;
Professor H Hodgson, Member, Academic Advisory Committee
Tea
Integrated Academic Training Programme in action :
Views of an ACF : (Dr J Dowman, Birmingham)
and (Dr W Alazawi,London)
Views of a Walport Lecturer (Dr S Halder, Manchester)
The role of CORE in supporting integrated academic training for
clinicians (Dr W Alexander and Dr JR Bennett, CORE)
Presentation of CORE/Dr Falk Pharma Student Research Award – Mr
Riadh Jazrawi
10
Wednesday 28 March
07:30 – 08.45
‘Question the Expert’ Breakfast Meeting – The Castle Suite of the Crowne Plaza Hotel
(adjacent to SECC)
‘Using biologicals in paediatric practice – when I use them and for how long’
(Professor A Griffiths, Toronto)
ENDOSCOPY/OESOPHAGEAL SYMPOSIUM : ‘Frontiers in
early oesophageal cancer : Advances in diagnosis and
management‘ : Clyde Theatre : Chair – Dr S Cairns and Mr T Dehn
Standards and advanced endoscopic techniques :
Standard Endoscopy and high resolution chromoendoscopy
(Dr B Rembacken, Leeds)
Narrow band imaging and autofluorescence
(Dr K Ragunath, Nottingham)
Fluorescence spectroscopy (Professor H Barr, Gloucester)
What’s the natural history of dysplasia and early oesophageal cancer?
(Dr D Johnston, Dundee)
Coffee
Teatment options :
Should lesions be resected endscopically?
(Dr J Bergman, Amsterdam)
The role of ablative therapies (Dr L Lovat, London)
Is surgery the Gold Standard? (Mr N Maynard, Oxford)
Clinical Cases – Panel Discussion
09.00-12.00
09.00-10.20
09.00-09.20
09.20-09.40
09.40-10.00
10.00-10.20
10.20-10.40
10.40-11.40
10.40-11.00
11.00-11.20
11.20-11.40
11.40-12.00
09.00-12.00
09.00-09.15
O-058
09.15-09.30
O-059
09.30-09.45
O-060
09.45-10.00
O-061
10.00-10.15
O-062
10.15-10.45
INFLAMMATORY BOWEL DISEASE FREE PAPERS : Lomond
Theatre : Chair – Dr T Orchard, Dr C Mowat, Dr AF Muller and
Dr B McKaig
An investigation into the prevalence of osteoporosis and the relative
contribution of genetic and environmental factors in patients with
inflammatory bowel disease (CL Noble, J McCullough, WK Ho,
ER Nimmo, S Bear, CW Lees, J Hannan, C Millar, SH Ralston,
J Satsangi)
Adalimumab maintains clinical remission and response, induces and
maintains healing of draining fistulas in patients with active Crohn’s
disease (MA Kamm, J Colombel, WJ Sandborn, P Rutgeerts,
RA Enns, SB Hanauer, R Panaccione, S Schreiber, KG Lomax,
PF Pollack)
Pregnancy outcome and fertility in inflammatory bowel disease is
influenced by disease phenotype. (CW Lees RE Gailer, NC Johnston,
P Warner, HO Critchley, J Satsangi)
Identification of GLI-1 as an IBD2 susceptibility gene (CW Lees,
ER Nimmo, A Tenesa, CL Noble, J Loane, H Campbell,
SEM Howie, MG Dunlop, J Satsangi)
Natalizumab maintains corticosteroid-free remission for 2 years in
patients with moderately to severely active Crohn's disease and in those
with prior infliximab exposure: results from an open-label extension
study (S Ghosh, R Panaccione)
Coffee
11
10.45-11.00
O-063
11.00-11.15
O-064
11.15-11.30
O-065
11.30-11.45
O-066
11.45-12.00
O-067
09.00-12.00
Replication of Crohn’s disease mucosal E Coli isolates within
macrophages and their susceptibility to antibiotics (S Subramanian,
CL Roberts, CA Hart, SW Edwards, BJ Campbell, JM Rhodes)
Adalimumab maintains clinical remission in patients with Crohn’s
disease (CD) without continued steroid use and regardless of anti-TNF
history or concomitant immunosuppressant therapy (MA Kamm,
J Colombel, GR D’Haens, WJ Sandborn, P Rutgeerts, SB Hanauer,
JD Kent, PF Pollack)
Further experience with the use of 6-thioguanine as an alternative
immunosuppressant in patients with Crohn’s disease (T Elliott,
A Ansari, S Soon, F Fong, B Baburajan, M Arenas-Hernandez,
A Marinaki, J Sanderson)
Medium-term results of oral tacrolimus treatment in refractory
inflammatory bowel disease (SC Ng, N Arebi, MA Kamm)
Tolerability of 6-mercaptopurine in azathioprine intolerant patients
with inflammatory bowel disease (CW Lees, AK Maan, B Hansoti,
ID Penman, AG Shand, KR Palmer, IDR Arnott, J Satsangi)
NEUROGASTROENTEROLOGY/MOTILITY SYMPOSIUM :
‘Neurogastroenterological manifestations of systemic disorders’ :
Hall 1 : Chair – Professor DG Thompson and Professor M Kamm
Management options for gastrointestinal dysfunction in spinal injuries
(Dr A Emmanuel, London)
Neurogenic gut disorders following stroke (Dr S Hamdy, Manchester)
Challenges in managing gastrointestinal complications of connective
tissue disorders (Dr G Lindberg, Stockholm)
Coffee
Diabetic gastroenteropathy: diagnosis and management
(Dr J McLaughlin, Manchester)
Gastrointestinal involvement in paraneoplastic syndromes: An
overview (Professor R de Georgio, Bologna)
Visceral involvement in extrapyramidal and demyelination disorders :
the neurologist’s perspective (Professor C Fowler, London)
09.00-09.25
09.25-09.50
09.50-10.15
10.15-10.45
10.45-11.10
11.10-11.35
11.35-12.00
12.05
STATE OF ART LECTURE : Hall 1 : Chair – Professor RC Spiller
‘Psychoneuroimmunology : a novel approach to functional gut
disorders’
Professor F Shanahan, Cork
09.00-12.00
ENDOSCOPY ASSOCIATES GROUP : Free papers, National
awards, sharing good clinical practice, Irene Cooper Prize : Carron
Theatre : Chair – Ms M Baulf and Ms A Reilly
09.00-10.15
COLORECTAL FREE PAPERS : Dochart Theatre : Chair Polyposis families without mutations have a less severe phenotype
(KJ Monahan, HJ Thomas, AR Silver, IP Tomlinson, RK Phillips)
Determinants of compliance to a community colorectal cancer
screening program in Lecco province (Italy) (FR Parente, R Moretti,
E Invernizzi, B Marino, N Cattai, E Masala, A Brusadelli, G Rossi)
09.00-09.15
O-068
09.15-09.30
O-069
12
09.30-09.45
O-070
09.45-10.00
O-071
10.00-10.15
O-072
10.45-12.15
10.45-11.00
O-V73
11.00-11.15
O-V74
11.15-11.30
O-075
11.30-11.45
O-076
11.45-12.00
O-V77
12.00-12:15
O-V78
09.00-11.00
09.00-09.20
09.20-09.40
09.40-10.00
10.00-10.20
10.20-10.40
10.40-11.00
Mass screening of colorectal cancer with an immunochemical faecal
occult blood test in Italy. Preliminary results in a pilot province
(FR Parente, B Marino, A Armellino, L Redaelli, E Invernizzi,
R Moretti, G Rossi)
Expression of colonic stem cell markers in colorectal cancer correlates
with a poor prognosis (SF Rahman Casans, ND Willis,
TR Cox, KM Smits, SA Przyborski, PA van den Brandt,
M van Engeland,M Weijenberg, A de Bruine, CJ Hutchison,
RG Wilson)
Colorectal stenting in malignant large bowel obstruction using
combination fluoroscopy and direct endoscopic placement: a
prospective 5-year evaluation (DP Hurlstone, W Baraza, SR Brown, F
Lee)
ENDOSCOPY VIDEOS : Dochart Theatre : Chair – Dr JRB Green
and Dr R Tighe
Endoscopic mucosal resection techniques for upper GI neoplasms:
video review (RJ Mead, M Duku, S Toh, P Bhandari)
Endoscopic submucosal dissection (ESD) for early oesophageal cancer:
technical feasibility and clinical applicability (P Bhandari,
S Hosking, I Oda)
An emerging 'gold standard' for the colonoscopic assessment of
ulcerative colitis: high magnification chromoscopy provides a valid in
vivo optical biopsy and extent assessment tool (DP Hurlstone,
DS Sanders, ME McAlindon, AJ Lobo, M Thomson, SS Cross)
Does changes towards safer sedation practices really improve
endoscopic outcomes? A re-audit following implementation of GRS,
BSG and NCEPOD recommendations (K Bowering, W Azim,
P Spencer, J McPhillips, L Brown, K Jones, R Sturgess, K Bodger,
S Sarkar)
First reported case of direct jejunostomy using a double balloon
enteroscope (CA Wadsworth, CH Fraser, DC Bullas, SM Gabe)
The first UK case of endoluminal fundoplication using the esophyx
device (PL Youd, AV Emmanuel, S Gould, E Tripoli, S Preston,
K Koniezko, C Fraser)
SMALL BOWEL AND NUTRITION/BAPEN SYMPOSIUM :
‘Educating RITA – in Clinical Nutrition’ : Alsh Theatre : Chair – Dr
JM Woodward and Dr DS Sanders
Fighting for funding and feeding: lessons in nutrition support
(Dr J Nightingale, London)
The impact of NICE guidance on clinical nutrition practice and training
(Dr MA Stroud, Southampton)
The SpR perspective of training in clinical nutrition (Dr S Karanth…)
A curriculum in clinical nutrition (Dr IW Fellows, Norwich)
Can the nutrition curriculum be delivered ( Dr I Forgacs, London)
Panel discussion
13
09.00-12.00
ENDOSCOPY ASSOCIATES GROUP : Regulations and new
guidance : Boisdale Theatre : Chair – Ms W Pugh
VRQ (vocational learning) : what does it mean for endoscopy nurses
(Ms A Keen, London)
2005 disinfection regulations : what do they mean to practice (TBA)
Coffee
New antibiotic guidelines; what’s new about it!
(Dr MC Allison, Newport)
Anticoagulants and the endoscopic procedure
(Dr A Veitch, Wolverhampton)
09.00-09.30
09.30-10.00
10.30-11.00
11.00-11.30
11.30-12.00
09.00-10.30
THE EVIDENCE BASE OF GASTROINTESTINAL CANCER
PREVENTION (on behalf of the National Cancer Research
Institute) : Leven Theatre
Session 1 : Chair : Dr J de Caestecker and Dr D Morris
Introduction (Dr J de Caestecker, Leicester)
Overview of cancer prevention
(Professor J Jankowski, Oxford and Leicester)
Screening and surveillance using BOSS
(Professor H Barr, Gloucester)
Chemoprevention using AspECT (Dr P Watson, Belfast)
Discussion
Session 2 : Chair : Mr G Fullarton and Mr S Attwood
What are large GI RCTs and why so rare
(Dr M Anderson, Birmingham)
What trials can we do and how you can help
(Professor P Malfertheiner, Germany)
Discussion
09.00
09.01-09.13
09.13-09.25
09.23-09.35
09.35-09.45
09.45-10.05
10.05-10.25
10.25-10.30
14.00-17.40
14.00-14.30
14.30-14.45
O-079
14.45-15.00
O-080
15.00-15.15
O-081
15.15-15.45
PLENARY SESSION : Clyde Theatre : Chair – Professor AI Morris
and Dr J de Caestecker:
NEW PERSPECTIVES LECTURE :
‘Privatising the English NHS – will Scotland follow suit?
Professor Allyson Pollock, Edinburgh
Chromoscopic confocal laser scanning in vivo biopsy for the detection
and characterisation of neoplastic lesions in high-risk colorectal cancer
cohorts: entering the era of histoendoscopy in the UK
(DP Hurlstone,M Thomson, W Baraza, SS Cross)
Risk of cancer in inflammatory bowel disease treated with azathioprine:
a UK population-based case-control study
(RG Armstrong, J West,TR Card)
The place of minimal access surgery amongst people with gastrooesophageal reflux disease (GORD): the REFLUX trial (A Grant,
M Thursz, for the REFLUX Trial Group)
SIR FRANCIS AVERY JONES BSG RESEARCH MEDAL :
‘Barrett’s carcinogenesis as a model for unraveling the clinical
challenges and opportunities of intra-epithelial neoplasia.’
14
Dr Rebecca Fitzgerald, (Cambridge)
Posters
Tea
Presentation of President’s Medal
CORE Award
Induction of Professor Michael Farthing, President 2007-8
SIR ARTHUR HURST MEMORIAL LECTURE :
‘The integrative action of the gut hormones’
Professor Graham Dockray, FRS (Liverpool)
15.45-16.15
16.15-16.45
16.45-16.55
16.55-17.00
17.00-17.05
17.05-17.40
17.45
Annual Business Meeting (Members only)
14.00-16.50
ENDOSCOPY ASSOCIATES GROUP ‘IBD Joint Symposium :
RCN Gastro Forum/IBD Section & EAG : Lomond Theatre :
Chair – Sr J Burdon and Ms K Greveson
Introduction
Defining the role of the IBD Nurse : an RCP project (Ms C Pearson,
Bolton)
NACC – a systematic review of nursing roles in IBD (Ms J Nahal,
Walsall)
Providing telephone services for IBD patients (Ms K Holbrook,
Gloucester)
Surviving as an IBD nurse in the new NHS (Ms I Mason, London)
Tea
Interactive IBD nurses – our website (Ms A Fraser, Bristol)
Using capsule endoscopy to enhance IBD care (Dr M McAlindon,
Sheffield)
IBD biologics – the practice behind the science (Dr A Lobo, Sheffield)
14.00-14.10
14.10-14.30
14.30-14.50
14.50-15.10
15.10-15.30
15.30-15.50
15.50-16.10
16.10-16.30
16.30-16.50
14.00-16.30
ENDOSCOPY ASSOCIATES GROUP : ERCP and service
requirements : Hall 1 : Chair : Ms L Melleney and Ms L Doig
Radiation protection; law and training ussues (Dr D Martin,
Manchester)
Specialist endoscopy assistants for ERCP (Sr J Gregory)
Tea
Managing a busy ERCP service the Amsterdam way (TBA)
Managing complications (Dr H Smart, Liverpool)
14.00-14.30
14.30-15.00
15.00-15.30
15.30-16.00
16.00-16.30
14.00-17.00
14.00-14.15
O-082
14.15-14.30
O-083
14.30-15.15
15.15-15.30
GASTROINTESTINAL PHYSIOLOGY ASSOCIATES GROUP :
Carron Theatre : Chair – Mrs P Vales and Dr RC Heading
The effect of pelvic afferent nerve stimulation on rectal compliance
(EAL Chung, V Balasubramaniam, MD Craggs, AV Emmanuel)
Evaluation of gastric function and control of migration of oesophageal
reflux after laparoscopic Nissen fundoplication (PJ Byrne,
N Ravi,P Lawlor, T Moran, M Byrne, P Keeling, J Reynolds)
Keynote Lecture : ‘How does the psyche affect gastrointestinal disease’
– Professor F Creed (Manchester)
Tea
15
15.30-16.15
16.15-16.30
16.30-16.45
O-084
16.45-17.00
O-085
14.00-17.00
Keynote Lecture : ‘Pain management in gastrointestinal disease’ – Dr
A Emmanuel (London)
Invited speaker
Gut symptoms in diabetes correlate with autonomic activity and
components of the recto-anal inhibitory reflex, not pudendal nerve
latencies (K Thiruppathy, DR Chatoor, AJ Roy, CDR Murray,
AV Emmanuel)
Bile acid malabsorption (BAM) and ileal histology in diarrhoeapredominant irritable bowel syndrome (D-IBS) (M Srinivas,
P Basumani, B Dawson, MJ Smith, JA Lee, KD Bardhan)
PATHOLOGY EQA AND SLIDE SEMINAR (Dochart Theatre)
16
Thursday 29 March
08.30-12.00
08.30-09.30
08.30-08.40
08.40-08.50
08.50-09.00
09.00-09.30
09.30-10.00
09.30-09.38
09.38-09.48
09.48-09.55
09.55-10.05
10.05-10.30
10.30-12.00
10.30-10.40
10.40-10.50
10.50-11.00
11.00-11.10
11.10-11.20
11.20-12.00
09.00-12.00
09.00-09.25
09.25-09.50
09.50-10.15
10.15-10.45
10.45-11.10
11.10-11.35
11.35-12.00
12.05
ENDOSCOPY SYMPOSIUM : ‘Ensuring quality in endoscopy’ :
Clyde Theatre : Chair – Dr JRB Geen and Dr SR Cairns
Training
JAG – where next (Dr KR Palmer, Edinburgh)
Moving towards excellence as an endoscopy trainer
(Professor JR Barton, Newcastle upon Tyne)
Quality control in training – Future of training
(Dr JR Anderson, Cheltenham)
Discussion
Avoiding infection in Endoscopy
Revised antibiotic prophylaxis guidelines (Dr MC Allison, Newport)
Endoscope decontamination in practice – does it wash?
(Ms E Thompson, London)
vCJD containment – cleaning up our act (Dr MC Allison, Newport)
Discussion
Coffee
Service
The GRS in England – two years on
(Dr AM Veitch, Wolverhampton)
Tartanising the GRF – endoscopy quality improvement in Scotland (Dr
PS Phull, Aberdeen)
Bowel cancer screening one year on (Dr MR Tighe, Norwich)
Bowel cancer screening : Up, running and looking to the future
(Mrs J Patnick, Sheffield)
Sustaining a high quality endoscopy service (Dr R Valori, Gloucester)
Discussion
PATHOLOGY/SURGERY SYMPOSIUM : ‘Colorectal cancer’ :
Lomond Theatre : Chair –Mr K Wedgwood and Professor NA
Shepherd
Genetics of high risk colorectal cancer
(Professor DM Eccles, Southampton)
Surveillance of the adenoma patient – including extracolonic
surveillance of polyposis patients (Professor W Atkin, London)
Pathology of polyposis syndromes (Professor GT Williams, Cardiff)
Coffee
CT colonography for symptomatic patients (Dr C Kay, Bradford)
Local excision of colorectal cancer
(Professor NJM Mortensen and Dr BF Warren, Oxford)
Patient-targeted therapy in colorectal cancer
(Professor M Seymour, Leeds)
BASIL MORSON LECTURE :|
‘On the shoulders of giants – clinicopathological insights into
colorectal cancer’
Professor P Quirke, Leeds
(This lecture is generously sponsored by Blackwell Communications)
17
‘Question the Expert’ Breakfast Meeting – Hall 1
‘Endoscopy in Primary Care; is this a new niche for the nurse
endoscopist’
Andrea Nicholls
07.30-08.45
This session is open to Nurse Endoscopists only
ENDOSCOPY ASSOCIATES GROUP : ‘Obesity and nutrition
support through nursing services; : Hall 1 : Chair – Ms S Harnden
and Ms P Hutson
Behavioural approach to weight loss (TBA)
Stomach banding – nurse-led service (Ms P Hutson, Sheffield)
Coffee
The obesity epidemic. Is there a surgical solution?
(Mr R Ackroyd , Sheffield )
Nutritional support; are the guidelines Nice?
(Ms L Colagiovannie, Birmingham )
Annual Business Meeting
09.30-12.30
09.30-10.00
10.00-10.30
10.30-11.00
11.00-11.30
11.30-12.00
12.00-12.30
09.00-12.00
ENDOSCOPY ASSOCIATES GROUP : Reports from the Regions
: Carron Theatre : Chair – Ms I Dunkley and Ms F Payton
North East Region (Ms L Hodgson)
Midlands Region (Ms L Mahachi)
East Anglia Region (Sr S Beesley)
Coffee
Northern Ireland Region (Ms J Cushley)
Regional groups meeting : question/answer session
09.00-09.30
09.30-10.00
10.00-10.30
10.30-11.00
11.00-11.30
11.30-12.00
09.00-12.00
09.00-09.15
O-086
09.15-09.30
O-087
09.30-09.45
O-088
09.45-10.00
O-089
10.00-10.15
O-090
10.15-10.45
09.00-12.00
09.00-09.30
GASTRODUODENAL FREE PAPERS : Dochart Theatre :
Chair – Professor E El-Omar and Professor KEL McColl)
Gender difference in gastric cancer is unrelated to gastric atrophy
(H Watabe, Y Yamaji, M Okamoto, T Kawabe, T Mitsushima,
M Omata, K McColl)
Inactivation of the second allele in patients with hereditary diffuse
gastric cancer harbouring germline E-cadherin mutations (ME Barber,
S Hyland, N Grehan, C Caldas, R Fitzgerald)
The clinical utility and diagnostic yield of routine gastric biopsies in
the investigation of iron deficiency anaemia (PV Kaye, K Garsed,
K Ragunath, A Jawhari, B Pick, J Atherton)
Administration of dimethyloxalylglycine (DMOG) as a novel
gastrointestinal repair strategy (A Mahmood, T Marchbank,
SK Harten, PH Maxwell, S Ghosh, RJ Playford)
Is mastic gum effective in the treatment of functional dyspepsia? A
randomized double-blind placebo controlled trial (KJ Dabos, E Sfika,
LJ Vlatta, D Frantzi, GI Amygdalos, G Giannikopoulos)
Coffee
PANCREATIC FREE PAPERS AND SYMPOSIUM :
‘Autoimmune pancreatitis’ : Alsh Theatre : Chair – Professor K
Conlon
Historical perspective, epidemiology and clinical presentation
18
09.30-10.00
10.00-10.30
10.30-10.40
10.40-11.00
11.00-11.15
O-091
11.15.-11.30
O-092
11.30-12.00
09.00-12.00
09.00-09.15
O-093
09.15-09.30
O-094
09.30-09.45
O-095
09.45-10.00
O-096
10.00-10.15
O-097
10.15-10.45
10.45-11.00
O-098
11.00-11.15
O-099
11.15-11.30
O-100
11.30-11.45
O-101
11.45-12.00
O-102
14.00-16.30
(Professor R Sutton, Liverpool)
Investigation and diagnostic criteria (Professor S Chari, Minnesota)
Treatment approaches and disease response
(Mr George Webster, London)
Panel Discussion
Coffee
Steroids in autoimmune pancreatitis (AIP) – do they preserve
pancreatic anatomy and function? (NS Sandanayake, NI Church,
R Dor, AR Hatfield, SP Pereira, GJ Webster)
Vitamin D in exocrine pancreatic insufficiency (EPI): a UK experience
(M Srinivas, P Basumani, RD Ellis, RC Lord,
KD. Bardhan)
Update on novel approaches to pancreatic cancer chemotherapy
(Professor W Steward, Leicester and Dr D Cunningham, London)
SMALL BOWEL/NUTRITION FREE PAPERS : Boisdale Theatre
: Chair – Dr DS Sanders and Dr P Watson
What are the best immunological tests for coeliac disease? – a
prospective assessment of 2000 biopsy verified results (AD Hopper,
DP Hurlstone, G Wild, DS Sanders)
What is the optimal site and number of endoscopic duodenal biopsies
required to diagnose coeliac disease? (AD Hopper, SS Cross,
DP Hurlstone, DS Sanders)
Prospective study of the prevalence of coeliac disease in adults with
Type 1 diabetes mellitus: effect upon glycaemic control and quality of
life (JS Leeds, AD Hopper, M Hadjivassiliou, S Tesfaye,
DS Sanders)
Long term followup of patients with malignant carcinoid syndrome
receiving Sandostatin LAR (JR Garland, C Bouvier, P Davies,
C Toumpanakis, J Buscombe, M Caplin)
Anti tissue transglutaminase antibody (TTG) quantification is useful in
the follow-up of coeliac disease patients (S Maitra, R Thomas,
A Mcleantooke, G Spickett, D Smith, R Ward, JC Mansfield)
Coffee
New introducer PEG-gastropexy without prophylactic antibiotics: a
prospective randomised double blind trial (YM Shastri, N Hoepffner,
A Tessmer, W Caspary, J Stein)
Incidence of refeeding syndrome in general medical inpatients on
enteral feeding. (N Sundar, A Green, R Taneja, M Williams, R Hill,
R Crimmins, J Green, G Swift)
Effect of microbial overgrowth on cytokine expression in the upper
gastrointestinal tract of patients receiving enteral nutrition (AR Smith,
GA O'May, E Furrie, B Bahrami, N Reynolds, GT Macfarlane)
Screening for malnutrition in outpatients (N Sundar, C Pride,
J Collins, A Clark, R Alcolado)
Training gastroenterologists in clinical nutrition (TR Smith,
AN Desilva, SA Wootton, AA Jackson, MA Stroud)
ENDOSCOPY ASSOCIATES GROUP : ‘Bowel screening and
service improvement’ : Lomond Theatre : Chair – Ms H Griffiths and
19
Ms L Coleman
Cancer screening service: where are we with it?
(Ms L Coleman , Sheffield )
Role of the specialist screening practitioner
(Wolverhampton Bowel Screening Team)
Tea
Global rating score and the new domains (Ms H Griffiths, Hereford)
Endoscopy: enhancing the nursing contribution (Ms R Hodson, Hull
and Ms D Johnston )
14.00-14.30
14.30-15.00
15.00-15.30
15.30-16.00
16.00-16.30
ENDOSCOPY ASSOCIATES GROUP : ‘Developments in GI
Disease : Hall 1 : Chair – Ms N Campbell
Double balloon enteroscopy (Dr C Fraser, London)
Capsule endoscopy : is it working? (TBA)
Tea
Hypnosis and its use in IBS (Dr G Smith, Edinburgh)
CT colonography (Dr D Burling, London)
14.00-16.30
14.00-14.30
14.30-15.00
15.00-15.30
15.30-16.00
16.00-16.30
Tuesday 27 to Thursday 29 March
Hall 5 – 12.30-14.00
CASE PRESENTATIONS COMPUTER WORKSHOP:
The following Case Presentations will be shown during the course of this session:
C-103
C-104
C-105
C-106
C-107
C-108
C-109
C-110
An unusual cause of acute lower gastrointestinal bleeding
(V Anumakonda, H Bu-Hayee, G Chung-Faye, S Diaz-Cano)
Relapsing, remitting obstructive liver function tests (JA Jupp,
S Bridger, CJ Hovell)
Watery diarrhoea, is it infective, iatrogenic or is there more to it?
(M Castelino, J Gasem, D Nazareth, B Hamid, TD Wardle)
From phlebolith to surgery (GW Moran, T Stone, A Wolinski,
R Patel, BJM Jones)
An unusual cause of gastric outlet obstruction (BJ Sebastian,
D Mittapalli, M Hussain, S Afzal, V Rudralingam, R Hammonds,
K Akhtar)
Cardiologists: beware of ulcers (J Mannath, R Polson)
Refractory pleural effusion from pancreato-pleural fistula: a rare
complication of chronic pancreatitis (GG Babu, VN Mahesh, M Patel)
An uncommon case of ascites (D Gupta, J Mannath, J Ostler, N Shah)
Tuesday 27 March
20
POSTER VIEWING SESSION: PLENARY, COLORECTAL/ANORECTAL,
GASTRODUODENAL, GASTROINTESTINAL PATHOLOGY,
NEUROGASTROENTEROLOGY/MOTILITY, OESOPHAGUS, PANCREAS,
RADIOLOGY, SERVICE DEVELOPMENT
(Posters will be on display from 0900-1700 daily and authors will be present for discussion
between1230-1400)
PLENARY
Poster round will be conducted by Professor AI Morris and
Dr A Harris
PP-111
PP-112
PP-113
PP-114
PP-115
PP-116
PP-117
PP-118
PP-119
PP-120
PP-121
PP-122
PP-123
PP-124
Lamin A/C status is a prognostic indicator in colorectal cancer
(TR Cox, KM Smits, S F Rahman-Casans, ND Willis,
PA van den Brandt, M van Engeland , MP Weijenberg, A de Bruine,
CJ Hutchison, RG Wilson, S Przyborski)
Increased biomarkers of colorectal carcinogenesis associated with
obesity and Roux-en-Y gastric bypass (RYGB) (A Sainsbury,
GG Robins, R Goodlad, S Pollard, MA Hull)
Diagnostic yield of endoscopic ultrasound (EUS)-guided Trucut biopsy
(TCB): experience from a tertiary referral centre
(HI Karageorgiou, PJ Fortun, K Ragunath, GP Aithal)
Endoscopic balloon dilatation and sequential stenting provides safe and
effective treatment of anastomotic strictures complicating orthotopic
liver transplantation (A Holt, M Silva, D Mirza,
D Thorburn, G Haydon)
Lauren subtyping of cardia cancer provides further evidence of two
distinct aetiologies (S Hansen, SE Vollset, MH Derakhshan,
V Fyfe, KJ Melby, S Aase, E Jellum, KEL McColl)
Myofibroblast Wnt-5A facilitates intestinal epithelial repair through a
non-canonical pathway (M Sebastian, A Mohamed, IR Sanderson,
L Kruidenier)
Drug delivery systems for treating inflammatory bowel diseases: the
extent to which gastrointestinal pH influences drug release from enteric
coated products (VC Ibekwe, HM Fadda, MK Khela,
DF Evans, GE Parsons, AW Basit)
Outcomes of corticosteroid and thiopurine use in a population-based
cohort of Crohn’s patients in Cardiff diagnosed 1996-2005
(SK Gunesh, BA Hawthorne, GA O’Thomas)
The long-term burden of inflammatory bowel disease: a large
epidemiological study of patients in Scotland (J Nicholls, D Clark,
L Kelso, A Knight, A Crowe)
Bone marrow transplantation induces remission in Crohn’s disease –
where do the cells go? (S Schier, M Brittan, N Direkze, R Jeffery,
MR Alison, NA Wright)
Haemophagocytic syndrome complicating liver transplant carries a
poor prognosis (AT Barnardo, W Bernal, N Heaton, M Heneghan,
J O'Grady, G Mufti, J Devlin)
Lymphocyte steroid sensitivity in severe alcoholic hepatitis
(SFW Kendrick, JM Palmer, DEJ Jones, CP Day)
Changes in portal blood flow and liver oxygenation following
intraportal injection of pancreatic islet-sized dextran beads (P Kooner,
M Juszczak, G Jones, B Mohammadi, A Kumar, S Powis, M Press)
Reproducibility of viscero-visceral and viscerosomatic sensitisation
21
PP-125
PP-126
PP-127
PP-128
PP-129
PP-130
induced by intra-duodenal capsaicin infusion (B Unsworth, Q Aziz
P Holzer, A Hobson)
The fermentable fibre substrate pectin can enhance tumour yield in the
ApcMin/+ mouse model of intestinal cancer (J Gruninger, N Mandir,
RA Goodlad)
Esomeprazole for treatment of unexplained chest pain in primary care:
a prospective randomised double-blind placebo-controlled multicentre
study (N Flook, P Moayyedi, J Dent, NJ Talley,
T Persson, B Karlson, M Ruth)
The new radiolabelled somatostatin analogue 90Yttrium-DOTAoctreotate for the treatment of metastatic neuroendocrine tumors :
initial results and tolerability in a series of 47 patients
(C Toumpanakis, A Quigley, R Srirajaskanthan, A Karpathakis,
A Krepska, A Davidson, T Meyer, J Buscombe, ME Caplin)
Is research within the British Society of Gastroenterology (BSG) in
decline? (RJ Atkinson, AD Hopper, A Razak, A Perera, A Rahim,
DS Sanders)
Making a mole hill out of a mountain; use of BSG guidelines and GRS
principles to regain waiting list control in endoscopy (P Jani,
K Safakish, K Yara, A Sabra, AU Jawhari)
Monoclonal antibodies to the coeliac immunodominant gliadin peptide
(HJ Ellis, S McLaughlin, D Dewar, T Suligoj, C O'Sullivan,
P Ciclitira)
COLORECTAL/ANORECTAL
Poster Round will be conducted by Mr K Wedgwood and
Dr S Riley
PT-131
PT-132
PT-133
PT-134
PT-135
PT-136
PT-137
PT-138
PT-139
Molecular analysis of bacterial diversity in healthy and cancerous
colonic mucosae (S Ahmed, GT Macfarlane, S Macfarlane)
Referral letters for 2 week wait for suspected colorectal cancer do not
allow a straight-to-test pathway (M Aljarabah, N Borley,
T Goodman, J Wheeler)
Preoperative cardiac assessment for elective pelvic colorectal cancer
surgery, do we need guidelines ? (M Aljarabah, J Wheeler,
T Goodman , N Borley)
A novel finding - global DNA hypomethylation in diverticular disease:
a pilot study (the BORICC study) (RP Arasaradnam,
D Commane, H Greetham, M Bradburn, IT Johnson, JC Mathers)
Novel preliminary findings of mitochondrial DNA (mtDNA) mutations
in colonic crypts of patients with diverticular disease
(The BORICC Study) (RP Arasaradnam, LC Greaves, D Commane,
H Greetham,M Bradburn, RW Taylor, DM Turnbull, JC Mathers)
Percutaneous endoscopic colostomy within
a tertiary referral
colorectal practice: evidence to support current NICE guidelines?
(W Baraza, S Brown, M McAlindon, P Hurlstone)
Flexible sigmoidoscopy and biopsy for investigation of diarrhoea : high
rate of microscopic abnormality in macroscopically normal mucosa
(J Burdsall, C Lim, M Ahmed)
The association of proximal colorectal neoplasia and distal polyps in a
large district general hospital (AJ Cairns, M Hendrickse, N Shariff)
Functional symptoms and their psychological correlates in patients with
a rectocoele and evacuation difficulties (DR Chatoor,
22
PT-140
PT-141
PT-142
PT-143
PT-144
PT-145
PT-146
PT-147
PT-148
PT-149
PT-150
PT-151
PT-152
PT-153
PT-154
PT-155
PT-156
PT-157
PT-158
NM Thoua, AV Emmanuel)
Components of the recto-anal inhibitory reflex correlate with gut
symptoms in functional and neuropathic conditions (DR Chatoor,
K Thiruppathy, P Dhanjal, AJ Roy, AV Emmanuel)
What does MR proctography add in comparison to fluoroscopic
proctography in patients with evacuation difficulty? (DR Chatoor,
AV Emmanuel, S Elneil, R Cohen, AC Windsor, J Osborne,
S Halligan , SA Taylor)
Mucosal bacterial isolates from human colon cancer induce nuclear
localisation of ß-catenin in human colon cancer epithelial cells
(PD Collins, LYu, JM Rhodes)
What is the best method for assessing severity in functional
constipation; evaluation of symptoms by the clinician performing
invasive investigation or self-assessment of QOL by the patient?
(S Cowlam, A Mackie, I Minty, S Milburn, E McColl, Y Yiannakou)
Can enterocutaneous fistula be effectively managed in a regional unit?
(VK Datta, S Dann, A Engledow, A Privitera, R Cohen, A Forbes,
A Windsor)
Rectal administration of high dose vancomycin is successful in
inducing remission of Clostridium difficile associated diarrhoea
(CDAD) which has failed to respond to standard therapy (KK Desai,
Y Yiannakou, PH Moncur)
Failed colonoscopy: the radiological solution for achieving colorectal
cancer targets (K Flood, S Jaggar, R Lowe, L Juby, J Davies)
Clostridium difficile: experience of the highly-virulent epidemic strain
027 (IR Gooding, MC Ikwueke, G Bioh, MS Khan, SM Greenfield)
Derivation of a score for identifying colorectal cancer in primary care
(WT Hamilton)
Results of surgical excision of recurrent rectal cancer (SK Kumarage,
KKI Deen) Dr Kumarage has been awarded a BSG Travel Fellowship
Using somatic APC mutations as clonal markers in colonic polyps
(SJ Leedham, C Thirlwell, J Hoare, I Tomlinson, NA Wright)
Laparoscopic anterior rectopexy improves both obstructed defaecation
and faecal incontinence in patients with rectal intussusception
(R Collinson, P Boons, P van Duijvendijk, T Ahmed, H Decosta,
C Cunningham, I Lindsey)
Side population characteristics and role of ß1 integrin in adhesion of
isolated human colonic crypt epithelial cells (S Samuel, A Robins,
J Webb, YR Mahida)
Assessment of macrophage function within the stroma of sporadic
colorectal polyps (MH Mclean, GI Murray, N Fyfe, GL Hold,
AG Mowat, EM El-Omar)
Assessment of inflammatory cell phenotype in sporadic hyperplastic
polyps (MH Mclean, GI Murray, N Fyfe, GL Hold, AG Mowat,
EM El-Omar)
Surveillance colonoscopy for adenomatous polyps - are we
compromising the patient care? (D Mittapalli, B Sebastian, K Akhtar)
Colorectal screening: what would you choose? (G Morrison,
A Varghese)
Colonic anatomical variations as seen by virtual colonoscopy scout
images why colonoscopy is technically challenging (AB Patrick,
G Erian, L Jackson, O Epstein)
Potassium channel blockade prevents increased colonic permeability
23
PT-159
PT-160
PT-161
PT-162
PT-163
during ischaemia: a novel therapeutic strategy to reduce sepsis
associated with liver surgery (A Loganathan, JE Linley, S Kopanati,
P Lodge, M Hunter, GI Sandle)
Streptococcus bovis bacteraemia - a marker for colonic and liver
disease (B Saravanan, N Abdullah, LR Jenkinson)
Comparison of high resolution magnification endoscopy, narrow band
imaging with magnification and chromoendoscopy with magnification
in the assessment of neoplastic and non neoplastic colorectal lesions
(R Singh, A Shonde, P Kaye, CJ Hawkey, K Ragunath)
Adenomatous polyps are uncommon in patients with ulcerative colitis
but increase the risk of developing colorectal cancer (V Subramanian,
A Banerjee, R Pollok)
Iron deficiency anaemia and thrombocytosis: predictors of mortality in
colorectal cancer (IJ Tanswell, R Desai, J Burdsall, M Hall,
R Ransford)
Colorectal cancer: mapping expression studies: from murine models
onto human disease (F Song, J Jenkins, A Jorgensen, A Clarke,
AJ Watson)
GASTRODUODENAL
Poster Round will be conducted by Dr M Pritchard and Dr D
Gillen
PT-164
PT165
PT-166
PT-167
PT-168
PT-169
PT-170
PT-171
PT172
PT173
PT-174
Mucosal associated bacterial diversity in the stomach and duodenum
(S Ahmed, GT Macfarlane, S Macfarlane)
Helicobacter pylori dupA is not associated with duodenal ulcers in
populations from South Africa, Scotland, China and USA
(RH Argent,JC Atherton)
ComH: isolation purification and characterisation of a unique H pylori
protein (K Kostidis, P Thackray, KD Bardhan, CW Potter, JR Sayers)
How robust is data collection in upper gastrointestinal cancer referrals
at local and national levels? (A Jamil, S Zaro, S Mukherjee,
M Guinane, V Kulhalli N U Beejay)
Gastric phenotype and GORD symptoms indicate two distinct
aetiologies of cardia cancer (MH Derakhshan, R Malekzadeh,
V Fyfe, A Yazdanbod, A Kazemi, N Rakhshani, R Didehvar,
M Sotoudeh, KEL McColl)
Evaluation of risk stratification in the co-prescription of
gastroprotectants in patients admitted to hospital (GA Doherty,
GC Harewood, SE Patchett, FE Murray)
To biopsy or not to biopsy?.. is coeliac serology the answer… the
guidelines say so…(AD Farmer, G Sadler, BT Cooper)
A cross-sectional survey to assess the usefulness of the Rome III
dyspepsia symptom subgroups in a large community sample
(AC Ford, AG Bailey, D Forman, ATR Axon, P Moayyedi)
Outpatient management of minor upper gastrointestinal haemorrhage
(NC Hare, U Warshow, J Stephens, N Hamad, LM Jackson,
P Thatcher, IA Murray, SH Hussaini, NP Michell, HR Dalton)
A comparison between Iraqi and Iranian Helicobacter pylori strains
(N Hussein, R Argent, D Letley, M Mohammadi, J Atherton)
Investigation and management of patients referred with non-responsive
coeliac disease; results of 110 cases (SD Mclaughlin,
DH Dewar, MW Johnson, HJ Ellis, PJ Ciclitira)
24
PT-175
PT-176
PT-177
PT-178
Investigating the relationship of social deprivation and rates of
Helicobacter pylori infection using stool antigen testing –analysis of
2368 cases (J Parr, A Saeed, K Collins)
Discrepancies between serology and histology for the diagnosis of
coeliac disease in a district general hospital. is this an unrecognised yet
common problem in hospitals throughout the UK? (RR Sweis,
L Pee, G Smith-Laing)
Upper gastrointestinal bleeding and the changing use of COX-2
specific non-steroidal anti-inflammatory drugs (AS Taha, J Angerson,
R Prasad, C McCloskey, RP Knill-Jones, O Blatchford)
Changing epidemiology of peptic ulcer bleeding - a prospective 10 year
whole community study (JM Thomson, U Basavaraju,
D Armour, AG Mowat, A Fraser)
GASTROINTESTINAL PATHOLOGY
Poster Round will be conducted by Dr A Bateman
PT-179
PT-180
PT-181
PT-182
PT-183
PT-184
PT-185
PT-186
The putative stem cell marker CD24 is present as variably glycosylated
isoforms in colorectal cancer (SJ Crook, D Jackson,
A Akinleye, J Kim, R Seth, N Watson, L Durrant, J Scholefield,
M Ilyas)
Novel and concomitant mutations of KRAS and BRAF in colorectal
cancer cell lines (SJ Crook, R Seth, D Jackson, I Tomlinson, M Ilyas)
Investigating epigenetic pathways in colorectal cancer (SJ Crook,
R Seth, D Jackson, M Ilyas)
Iron induced upper GI erosions: a common pathological finding
(PV Kaye, J Wood, K Abdulla, PD James, JC Atherton)
A blinded comparison of capsule endoscopy and histology in the
evaluation of non-responsive coeliac disease (L Maiden, T Elliott,
D Dewar, P Ciclitira)
Natural polymorphism in the Helicobacter pylori vacuolating cytotoxin
signal sequence affects toxin production (CG Masters,
DP Letley, JC Atherton)
Vitamin D controls CDX-1 and 2 tumour suppressor function in
colorectal cancer (J Murphy, S Khalaf, RE Hands, S Dorudi,
CLH Chan, NS Williams, SA Bustin)
HOX gene gradients which pattern the embryonic gut are also present
in the adult human gut (J Murphy, S Khalaf, RE Hands, CLH Chan
SA Bustin, NS Williams)
NEUROGASTROENTEROLOGY/MOTILITY
Poster Round will be conducted by Dr A Emmanuel and Dr S
Hamdy
PT-187
PT-188
PT-189
Abdominal distension is related to delayed gastrointestinal transit in
irritable bowel syndrome with constipation (IBS-C) (A Agrawal,
PJ Whorwell, B Reilly, LA Houghton)
Is visceral hyposensitivity associated with abdominal distension in the
irritable bowel syndrome (IBS)? (A Agrawal, R Lea, PJ Whorwell,
LA Houghton)
Irritable bowel syndrome in the elderly: an overlooked problem?
(A Agrawal, MH Khan, PJ Whorwell)
25
PT-190
PT-191
PT-192
PT-193
PT194
PT-195
PT-196
PT-197
PT-198
PT-199
PT-200
PT-201
PT-202
PT-203
What is the optimal duration of oesophageal pH measurement and
symptom assessment? a prospective study using 96hr Bravo™
recordings (R Canavan, M Fox, A Anggiansah, T Wong)
Is targeting locus of control a desirable outcome of biofeedback in
functional constipation? (AV Emmanuel, JB Storrie, L Butcher,
J Duncan, C Norton, MA Kamm)
Using the gut response to acute stress to study the pathophysiology of
irritable bowel syndrome (IBS) (AV Emmanuel, NM Thoua,
W Wincester, CDR Murray)
Poor quality of life predicts the new onset of irritable bowel syndrome:
a longitudinal 10-year follow-up study (AC Ford,
AG Bailey, D Forman, ATR Axon, P Moayyedi)
Who consults with irritable bowel syndrome? a longitudinal 10-year
follow-up study (AC Ford, AG Bailey, D Forman, ATR Axon,
P Moayyedi)
Group 1 voltage-gated potassium channels in the gastrointestinal tract:
distribution and potential mediators of motility dysfunction
(AW Hubball, R Patel, M Baker, A Chambers, J Powell-Tuck,
C Knowles, J Martin)
Gastrointestinal symptoms in patients with Marfan syndrome
(BBN Scoones, AH Child, JY Kang)
The relationship between exocrine pancreatic hypofunction and
patients fulfilling the Rome II criteria for irritable bowel syndrome
(diarrhoea predominant, D-IBS): a prevalence study with controls and
therapeutic outcomes (JS Leeds, AD Hopper, A Simmonette,
N Azadbakht, S Morley, DP Hurlstone, DS Sanders)
Rectal endocrine cells: no post-inflammatory hyperplasia in colitis
(SE Levison, DA Levison, R Hammonds, J McLaughlin)
Abnormalities of small bowel and colonic water content in diarrhoeapredominant irritable bowel syndrome (IBS-D): novel insights from
magnetic resonance imaging (L Marciani, S Foley, CL Hoad,
E Campbell, JJ Totman, E Cox, PA Gowland, RC Spiller)
Factors determining the perception of the reflux events in GORD
patients (UR Marreddy, E Yazaki, DDF Evans, KK Mannur,
AA Jenkinson)
Exploring psychophysiological phenotypes for visceral pain
(PA Paine, SF Worthen, Q Aziz)
Blood pressure responses to distal oesophageal acidification and their
relationship to sensitisation in a human model of visceral pain
hypersensitivity (A Sharma, P Paine, B Unsworth, K Parvez,
J Spibey, Q Aziz)
Functional heartburn patients with somatisation trait demonstrate
generalised visceral hypersensitivity (NM Thoua, C Kalantzis,
A J Roy, AV Emmanuel)
OESOPHAGUS
Poster Round will be conducted by Dr M Dakkak, Dr K Kapur, Dr
J-Y Kang and Dr M Thomson
PT-204
The effects of obesity on oesophageal function and acid exposure in
patients with reflux symptoms (R Anggiansah, A Anggiansah, M Fox,
T Wong)
26
PT-205
PT-206
PT-207
PT-208
PT-209
PT-210
PT-211
PT-212
PT-213
PT-214
PT-215
PT-216
PT-217
PT-218
PT-219
PT-220
PT-221
PT-222
Inflammation and Barrett's metaplasia; the role of TNFɑ in clonal
expansion (AM Nicholson, PA Atherfold, A Cerbinskaite,
JA Jankowski)
A role for nitric oxide in the invasive process in oesophageal
adenocarcinoma (NJ Clemons, R Abeyratne, N Shannon,
RC Fitzgerald)
Risk of mortality and cancer incidence in Barrett’s oesophagus
(MB Cook, CP Wild, SM Everett, LJ Hardie, D Forman)
Oesophageal carcinoma in the West Midlands: changing incidence and
the influence of socio-economic status and ethnicity (SC Cooper,
R Day, C Brooks, C Livings, NJ Trudgill)
Chronic atrophic gastritis is a major risk factor for oesophageal
squamous cell carcinoma (MH Derakhshan, R Malekzadeh, V Fyfe,
A Yazdanbod, A Kazemi, N Rakhshani, R Didehvar, M Sotoudeh,
KEL McColl)
Acid-related oesophageal sensitivity not dysmotility differentiates
subgroups of patients with non-erosive reflux disease (D Khoo,
NM Thoua, C Kalantzis, CDR Murray, AV Emmanuel)
COX-2 and INOS gene polymorphisms in the reflux oesophagitisBarrett’s oesophagus - oesophageal adenocarcinoma sequence
(HR Ferguson, HR Ferguson, LJ Murray, BT Johnston,
LA Anderson,SJ Murphy, P Watson, J McGuigan, JV Reynolds,
H Comber, CP Wild, LJ Hardie)
Polymorphisms in DNA repair genes and their associations with risk of
reflux oesophagitis, Barrett’s oesophagus and oesophageal
adenocarcinoma (HR Ferguson, HR Ferguson, LJ Murray,
BT Johnston, LA Anderson, SJ Murphy, P Watson, J McGuigan,
JV Reynolds, H Comber, CP Wild, LJ Hardie)
Ornithine decarboxylase as a marker of dysplasia in Barrett’s
oesophagus (M Fullard, P Neild, A Poullis, JD Maxwell, JY Kang)
The relevance of low-grade dysplasia in columnar-lined oesophagus
(P Gatenby, JR Ramus, CPJ Caygill, A Watson)
Effectiveness of two week rule referral system for patients with
symptoms of dysphagia (AR Khan, B Khan, M Ali, Z Mahmood)
Non-endoscopic immunocytological screening test for Barrett’s
oesophagus (P Lao-Sirieix, B Rous, M O'Donovan, S Gardiner,
I Debiram, RH Hardwick, R Fitzgerald)
Elastic scattering spectroscopy for the detection of aneuploidy in
Barrett’s oesophagus (GD Mackenzie, D Oukrif, S Green,
MR Novelli, SG Bown, LB Lovat)
The presence of aneuploidy following photodynamic therapy predicts
late relapse to high-grade dysplasia or adenocarcinoma
(GD Mackenzie, D Oukrif, MR Novelli, S Green, SG Bown, LB Lovat)
Prospective trial of laparoscopic Nissen fundoplication versus proton
pump inhibitor therapy for gastro-oesophageal reflux disease: sevenyear follow-up (S Mehta, J Bennett, D Mahon, M Rhodes)
The effects of oral supplementation with n-3 fatty acids on Barrett's
epithelium in humans (S Mehta, AP Boddy, J Cook, EK Lund,
V Sams, IT Johnson, M Rhodes)
Oesophageal metal stents - not exactly 'fire and forget'
(EM Melleney, P Willoughby)
HB-EGF and TGF-ɑ mediate leptin-induced epidermal growth factor
transactivation and proliferation in oesophageal adenocarcinoma cells
27
PT-223
PT-224
PT-225
PT-226
PT-227
PT-228
PT-229
(OO Ogunwobi, IL Beales)
Globular adiponectin inhibits leptin-induced proliferation of
oesophageal adenocarcinoma cells via activation of adiponectin
receptor-1 (OO Ogunwobi, IL Beales)
Audit on Barrett’s columnar-lined oesophagus surveillance in a district
general hospital: the implications of BSG guidelines (J Ong,
D Gopalkrishnan, L Thomas)
Interventions for chronic cough associated with gastro-oesophageal
reflux: systematic review and meta-analysis of randomised controlled
trials (C Osonnaya, K Osonnaya, S Smith, L Guo, M Abdi)
Novel genomic aberrations in oesophagogastric cancer (JR Rees,
S Chin, JC Marioni, C Caldas, V Save, B Ylstra, D Alderdson,
RH Hardwick, RC Fitzgerald)
The utility of endoscopic tri-modal imaging for the detection of
dysplastic lesions in Barrett's oesophagus (K Ragunath, R Singh,
WL Curvers, P Fockens, JJ Bergman)
Risk factors for Barrett’s oesophagus among middle-aged men with
reflux disease: a case-control study (N Stern, K Bodger)
Development of a new scoring system to predict endoscopic diagnosis
in patients with dysphagia (I Tyrmpas, L Meekison, C Scott,
K Trimble, ID Penman, G MacDougall, JN Plevris)
PANCREAS
Poster round will be conducted by
PT-230
PT-231
PT-232
PT-233
PT-234
PT-235
Evaluation of the use of CA 19-9 in the setting of a district general
hospital (T Dickel, A Gera, M Lancaster-Smith, H Curtis)
Vascular endothelial growth factor and calprotectin in blood and bile
for diagnosis of pancreatobiliary carcinoma: a pilot study
(JE East, S Troup, J Mawdsley, L Jiao, N Habib, D Westaby,
D Bansi, B Muller, AV Thillainayagam)
Pancreatic function tests from patient point of view: a questionnaire
survey (SK Enaganti, S Shah, AC Wicks)
Clinical impact of symptomatic recurrent chronic pancreatitis in
patients with cystic fibrosis (J Puleston, C Groves, IR Gooding,
P Vlavianos, KM Gyi, M Hodson, D Westaby)
Are the BSG guidelines on pancreatic cancer achievable? (V Mitra,
M Kurmani, B Chaudhury, C Berthou, J Vasani)
Endoscopic ultrasound guided tissue sampling by combined fine needle
aspiration and trucut needle biopsy for the diagnosis of pancreatic
neuroendocrine tumors (SN Sgouros, M Caplin,
SP Pereira)
RADIOLOGY
Poster round will be conducted by Dr S Lee
PT-236
PT-237
PT-238
Wide angle 3D endoluminal CT colonography: impact on missed areas
and polyp conspicuity (JE East, BP Saunders, D Boone,
S Halligan, SA Taylor)
Small bowel imaging: comparison of small bowel magnetic resonance
imaging with small bowel follow through (D Subedi, S Glancy)
Determining the proximal extent of ulcerative colitis: white cell scan
28
correlates well with histological assessment (V Subramanian,
A Banerjee, N Beharry, M Farthing, R Pollok)
SERVICE DEVELOPMENT
Poster round to be conducted by Dr R Valori and Dr N Haslam
PT-239
PT-240
PT-241
PT-242
PT-243
PT-244
PT-245
PT-246
PT-247
PT-248
PT-249
PT-250
PT-251
PT-252
PT-253
PT-254
PT-255
PT-256
Blood count monitoring of azathioprine is improved by inflammatory
bowel disease nurse supervision (S Abusin, H Thompson-Jones,
B Hawthorne)
Feasibility of using an electronic HRQOL questionnaire routinely in
patients attending a busy gastrointestinal outpatients department – time
involvement and symptom reporting (F Ali, J Williams, D Russell,
I Russell)
Is outsourcing of dictation cheaper than medical secretaries?
(R Haidry, NU Beejay)
Copy letters to patients use and impact on workload (A Saeed,
S Bradbury, DW Bullimore)
An “endoscopy outcomes sheet” improves patient experience after
endoscopic procedures: results of a pilot study at a district general
hospital (K Pinder, A Allan, A Wilson, A Dhar)
The investigation of iron deficiency with or without anaemia
(R Mason, A J Dimambro, J Sufflebotham, CS Probert)
Informed consent: do subjects understand the information sheets?
(P J Fortun, L Chalkley, A Shonde, J West, C Hawkey)
The changing pattern of referrals for upper gastrointestinal cancer
2001-2005
(A Gera, R Evans, RJ Ede)
The impact of a 24-hour telephone helpline on the management of
patients with inflammatory bowel disease (IBD) (S Gethins,
T Duckett, J Mayberry, J de Caestecker, R Robinson)
Outcome of a nurse-led outreach service for prison inmates with
chronic Hepatitis C infection (EB Hills, M Allen, R Kitchen,
PL Collins, A McCune, FH Gordon)
A web-based endoscopy referral and triage system for quality assurance
(R Kasturi, E Said, G Clifford, J Singh, A Saeed)
A prospective audit of a nurse-led iron deficiency anaemia service in
compliance with the BSG guidlines (K Kemp, JM Hebden, AJ Makin)
Red cell distribution width - another useful index for iron deficiency (A
Koulaouzidis, E Said, S Bhat, J Moschos, I Shahzad,
AA Saeed)
The development of a county wide long-term follow-up service for
patients with gastrostomy tubes results in significant benefits for
patients and carers the local primary care trusts and the district general
hospital (M Scott, IA Murray)
Validating the planned colonoscopy waiting list: worth the effort?
(IA Murray, H Hussaini)
Dysphagia hotline: the first 600 patients (M Prince, R Abbott,
C Waters, HR Dalton, IA Murray)
Gastrointestinal tract pathology in patients with asymptomatic anaemia
and chronic kidney disease (N Powell, A McNair)
Improving colonoscopy services using action audit (JW Rademaker,
JM Morris)
29
PT-257
PT-258
PT-259
PT-260
PT-261
PT-262
PT-263
PT-264
The gender imbalance in academic medicine: have we bridged the gap
over 35 years, a UK perspective? (R Sidhu, A Key,
SE Erskine, J Walmsley, DS Sanders)
Capsule endoscopy:is formal training necessary for specialist registrars
in gastroenterology ? (R Sidhu, PV Sakellariou,
ME McAlindon, AD Hopper, BS Höeroldt, JS Leeds, M Karmo,
DS Sanders)
Patient access times and survival before and after introduction of a
rapid access upper gastrointestinal cancer service
(N Stern, N Kapoor, R Sturgess, K Bodger)
Evaluation of efficacy of an endoscope storage and drying chamber in
an endoscopy unit and its impact on working practice (S Thomas,
S Watts, E Saum, AP Chilton)
Usefulness of a dedicated nurse specialist-led clinic for familial
colorectal cancer (T Thomas, JR Bebb, W Chorley, AT Cole)
A multidisciplinary approach to percutaneous endoscopic gastrostomy
reduces the number of inappropriate procedures and decreases
mortality (DG Walker, AV Haycock, J Hoare, RPM Negus)
Nurse specialist iron deficiency anaemia service arising from audit
findings (C Dipper, S Hope, MR Welfare, M Hayat, C Tiplady)
Improving outcome in upper gastrointestina haemorrhage by service
development: a prospective audit in a district general hospital
(S West, L Wentworth, E Donaldson, C Pearson, GR Lipscomb)
Wednesday 28 March
POSTER VIEWING SESSION: PLENARY, ENDOSCOPY, GI PHYSIOLOGY
INFLAMMATORY BOWEL DISEASE, LIVER, NUTRITION, SMALL BOWEL
(Posters will be on display from 0900-1700 daily and authors will be present for discussion
between1230-1400)
PLENARY
Poster round will be conducted by Professor MJG Farthing and
Professor CU Nwokolo
PP-111
PP-112
PP-113
PP-114
PP-115
Lamin A/C status is a prognostic indicator in colorectal cancer
(TR Cox, KM Smits, SF Rahman-Casans, ND Willis, PA van den
Brandt, M van Engeland, MP Weijenberg, A de Bruine,
CJ Hutchison, RG Wilson, S Przyborski)
Increased biomarkers of colorectal carcinogenesis associated with
obesity and Roux-en-Y gastric bypass (RYGB) (A Sainsbury,
GG Robins, R Goodlad, S Pollard, MA Hull)
Diagnostic yield of endoscopic ultrasound (EUS)-guided Trucut biopsy
(TCB): experience from a tertiary referral centre
(HI Karageorgiou, PJ Fortun, K Ragunath, GP Aithal)
Endoscopic balloon dilatation and sequential stenting provides safe and
effective treatment of anastomotic strictures complicating orthotopic
liver transplantation (A Holt, M Silva, D Mirza,
D Thorburn,G Haydon)
Lauren subtyping of cardia cancer provides further evidence of two
distinct aetiologies (S Hansen, SE Vollset, MH Derakhshan,
V Fyfe, KJ Melby, S Aase, E Jellum, KEL McColl)
30
PP-116
PP-117
PP-118
PP-119
PP-120
PP-121
PP-122
PP-123
PP-124
PP-125
PP-126
PP-127
PP-128
PP-129
PP-130
Myofibroblast Wnt-5A facilitates intestinal epithelial repair through a
non-canonical pathway (M Sebastian, A Mohamed, IR Sanderson,
L Kruidenier)
Drug delivery systems for treating inflammatory bowel diseases: the
extent to which gastrointestinal pH influences drug release from enteric
coated products (VC Ibekwe, HM Fadda, MK Khela,
DF Evans,GE Parsons, AW Basit)
Outcomes of corticosteroid and thiopurine use in a population-based
cohort of Crohn’s patients in Cardiff diagnosed 1996-2005
(SK Gunesh, BA Hawthorne, GA O’ Thomas)
The long-term burden of inflammatory bowel disease: a large
epidemiological study of patients in Scotland (J Nicholls, D Clark,
L Kelso, A Knight, A Crowe)
Bone marrow transplantation induces remission in Crohn’s disease –
where do the cells go? (S Schier, M Brittan, N Direkze, R Jeffery,
MR Alison, NA Wright)
Haemophagocytic syndrome complicating liver transplant carries a
poor prognosis (AT Barnardo, W Bernal, N Heaton, M Heneghan,
J O'Grady, G Mufti, J Devlin)
Lymphocyte steroid sensitivity in severe alcoholic hepatitis
(SFW Kendrick, JM Palmer, DEJ Jones, CP Day)
Changes in portal blood flow and liver oxygenation following
intraportal injection of pancreatic islet-sized dextran beads (P Kooner,
M Juszczak, G Jones, B Mohammadi, A Kumar, S Powis, M Press)
Reproducibility of viscero-visceral and viscerosomatic sensitisation
induced by intra-duodenal capsaicin infusion (B Unsworth, Q Aziz
P Holzer, A Hobson)
The fermentable fibre substrate pectin can enhance tumour yield in the
ApcMin/+ mouse model of intestinal cancer (J Gruninger, N Mandir,
RA Goodlad)
Esomeprazole for treatment of unexplained chest pain in primary care:
a prospective randomised double-blind placebo-controlled multicentre
study (N Flook, P Moayyedi, J Dent, NJ Talley,
T Persson, B Karlson, M Ruth)
The new radiolabelled somatostatin analogue 90Yttrium-DOTAoctreotate for the treatment of metastatic neuroendocrine tumors :
initial results and tolerability in a series of 47 patients
(C Toumpanakis, A Quigley, R Srirajaskanthan, A Karpathakis,
A Krepska, A Davidson, T Meyer, J Buscombe, ME Caplin)
Is research within the British Society of Gastroenterology (BSG) in
decline? (RJ Atkinson, AD Hopper, A Razak, A Perera, A Rahim,
DS Sanders)
Making a mole hill out of a mountain; use of BSG guidelines and GRS
principles to regain waiting list control in endoscopy (P Jani,
K Safakish, K Yara, A Sabra, AU Jawhari)
Monoclonal antibodies to the coeliac immunodominant gliadin peptide
(HJ Ellis, S McLaughlin, D Dewar, T Suligoj, C O'Sullivan,
P Ciclitira)
ENDOSCOPY
Poster round will be conducted by Dr D Westaby, Dr H Smart, Dr
H Shepherd and Dr M Denyer
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Self appraisal and assessment of technical skills in endoscopic
procedures (TF Albrani, F Zaman, B Patel, S Sarker)
Endoscopy in people at risk of vCJD: from scope quarantined to access
denied (MC Allison, G Dolan)
Colonoscopic surveillance for ulcerative colitis in a large district
general hospital- is the juice worth the squeeze? (JR Bebb, L Coppel, T
Thomas, AF Goddard)
Is fluid deprivation required prior to endoscopy (DW Bowen,
M Webberley, N Cross, M Hurley, P Neville)
The need for nurse-led pre-assessment in a community based
endoscopy clinic (JP Bridges, AF Horgan, E Stoker)
Success of repeat ERCP following initial therapeutic failure
(NI Church, EW Seward, SP Pereira, AR Hatfield, GJ Webster)
Do UC what i see? Impact of endoscopy scoring on the outcome of a
clinical trial (R Cooney, M Lukas, E Butruk, I Kotzev, BF Warren,
P Krzeski, D Schnell, B Yacyshyn, C Bernhardt, M Abreu, S Travis)
Management of benign biliary strictures: endoscopy vs surgery
institutional experience (OM Damrah, A Lauretta, A Thillinianagram,
D Bansi, L Jiao, R Canelo, N Habib)
Is there evidence for myocardial damage in patients undergoing ERCP?
(AN De Silva, K Smith, L Bowman, PR McCrudden,
J Begley)
Open access endoscopy – are patients being appropriately referred and
prioritised according to national guidelines? (CR Dipper, D Elliott,
MD Warren)
Refining the indications for usage of wireless oesophageal video
capsule endoscopy in the investigation of the upper digestive tract
(S Douglas, JF Pendlebury, JN Plevris)
Trends in upper gastrointestina bleeding: a single centre experience of
over 1200 patients (P Eadala, R Crimmins, S Dolwani, GL Swift,
JT Green)
Polyp detection rate is improved with position changes during
colonoscope withdrawal: a randomised crossover trial mid-point
analysis (JE East, M Stavrinidis, N Arebi, N Palmer, P Bassett,
BP Saunders)
Facial response to anaesthetic spray is a predictor of patient tolerance
for gastroscopy (A Evans, S Papathomas, SD Mann)
Leeds discomfort score in colonoscopy patients and nurses disagree
(A Ghanbari, T Cuming, A Ballinger, H Pardoe)
Paediatric endoscopy performed by general gastroenterologists
(JO Hayat, R Sirohi, DA Gorard)
Lack of alarm symptoms at first presentation is common in patients
subsequently found to have gastric or oesophageal carcinoma
(M Hegde, RAJ Ransford, MJ Hall)
JAG colonoscopy training guidelines are not being met by trainees
following a one-to-one hands-on colonoscopy training course
(AV Haycock, P Youd, N Suzuki, S Thomas-Gibson, BP Saunders)
Have changes to sedation practice in endoscopy affected the incidence
of sedation overdose (A Humphries, A Thillainayagam, J Mawsdley,
N Bhuva, T Shepherd, D Bansi)
Dextrose solution is as effective as sodium hyaluronate for the
resection of colorectal Paris type I and 0-II lesions: a randomised
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blinded study (DP Hurlstone, DS Sanders, R Atkinson,
ME McAlindon, AJ Lobo, M Thomson, SS Cross)
Magnetocolonoscopy (A Jaganathan)
Dr Jaganathan has been awarded a BSG Travel Fellowship
Interobserver agreement in capsule endoscopy reporting between
trainee and consultant gastroenterologists (S John, D Kejariwal,
C Jamieson)
Does management of an acute upper gastrointestina haemorrhage
warrant the need for a 24-hour endoscopy service? (AM Karim,
P Ellul, D Moothoo,A Sewart, HM Pratt, BA Teague, R Sekhar,
C Brown, JJ Keating)
Is poor endoscopic technique leading to missed cancer diagnoses?
(AJ Kent, AM Milestone, J Hoare)
Diagnostic yield of colonoscopy in chronic diarrhoea (AR Khan,
M Riazuddin, K Hafeez, M Ali, B Javaid)
Long term five year prospective follow up of Endocinch© therapy for
gastro-oesophageal reflux disease (GORD): retention of plications are
essential to control GORD (Z Mahmood, R Messersmith, A Zaheer,
N Mahmud)
A study to assess expertise and training in Sengstaken-Blakemore tube
placement amongst trainee gastroenterologists (PF Marden,
B Colleypriest, D Gavin, M Farrant)
Abdominal pressure during colonoscopy - a survey to assess attitudes
and training amongst endoscopy nurses (PF Marden, V Cambridge,
B Colleypriest)
Audit of 30D mortality following PEG insertion at a district general
hospital, The Kent and Sussex Hospital, Tunbridge Wells, Kent:
compared with NCEPOD results (S D McLaughlin, AW Harris)
Long-term five year follow-up of patients with iron deficiency anaemia
after a negative gastrointestinal evaluation
(MT McLoughlin, TCK Tham)
Sedation for endoscopic procedures- are we safe enough?
(M McMahon, P Dunne, GR Lipscomb)
Five-year experience with endoclips in the management of
gastrointestinal bleeding
(F Mohammed, K Peddi, C Babbs)
Direct percutaneous endoscopic jejunostomy – technique and a
five-year review (GW Moran, NC Fisher)
Preoperative staging of pancreaticobiliary tumours - the role of
endoscopic ultrasound with EUS fine needle aspiration when computed
topography is inconclusive (C Mountford, M Nayar,
B Jacques, J Scott, D Manas, R Charnley, V Wadhera, K Oppong)
Sensitivity and specificity of ERCP brushings of suspected malignant
biliary strictures (WP Murphy, TC Tham, P Kelly, GR Caddy)
Role of repeat endoscopic ultrasound guided fine needle aspiration in
obtaining tissue diagnosis in solid pancreatic lesions – is it worthwhile?
(MK Nayar, V Wadehra, M Egan, KN Oppong)
Flexible sigmoidoscopy in the community: is medical supervision
necessary? (PM O’Loughlin, E Stoker, AF Horgan, K Chalam)
Perception of the malignant potential of gastric ulcers is influenced by
acid suppressing medication (SJ Panter, M Bramble, P Hungin,
R Jones)
Inadequate numbers of biopsies results in delayed diagnosis of upper
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GI adenocarcinoma (SJ Panter, M Bramble, P Hungin, R Jones,
H O'Flanagan)
Size doesn't matter: safety and efficacy of ERCP in a small district
general hospital (TA Mehta, K Ofuafor, KA Roberts, DR Parker)
Do variable stiffness colonoscopes improve examination completion
rates? analysis of 4463 cases (J Parr, A Saeed, J Singh)
Exploring the utility of the given patency capsule in patients at risk of
capsule retention (AJ Postgate, A Fitzpatrick, C Fraser)
A single-blinded randomised controlled trial assessing the optimal
bowel preparation for the capsule endoscopy test (AJ Postgate,
A Fitzpatrick, N Patterson, C Fraser)
Common bile duct width, as measured by endoscopic ultrasound
increases with age and post- cholecystectomy (SL Preston, V Kwan,
ID Norton, DB Jones)
The additional value of Cusum charts for colonoscopy training
(G Bowler, G Waddup, S Masson, MD Rutter)
Diagnostic yield of investigations in patients with hepatic metastasis
(SS Salunke, A Badar, N Jamieson, A Cahill)
Percutaneous endoscopic gastrostomy: improved patient selection and
30-day mortality rates after a change in clinical practice
(M Shariff, A Milestone, L McEvoy, C Collins, I Beveridge,
K Sundaram, S Kane)
Single-centre, single-operator ERCP experience in a district general
hospital (RG Shidrawi, NCZ Chua)
Fibred confocal endmicroscopy: a feasibility study to enhance routine
endoscopy (A Shonde, R Singh, P Kaye, CJ Hawkey, K Ragunath)
The safety, efficacy and clinical outcomes of endoscopic mucosal
resection: experience from a tertiary referral centre (R Singh, K Yao,
A Shonde, P Kaye, K Ragunath)
Benefits of pre-assessment in PEG patients (LC Skitt, AJ Green,
K Cracknell, JT Green, GL Swift)
Change in bowel habit to constipation: is flexible sigmoidoscopy
indicated? (MJ Sproat, S Kanagalingam, ZH Khan, J Gotto)
Gastrointestinal bleeding and coagulopathy: worth getting out of bed
for? (S Taslaq, M Vinayaga-Pavan, G Mehta, B Ancock, K Patel,
D Bansi, A Thillainayagam)
Acute oesophageal necrosis or just another black oesophagus?
(S Thomas-Gibson, GT Kingston, AS Mee)
What are the key components of hands-on colonoscopy training?
(A I Thuraisingam, AH Shenoy, JT Anderson)
Trainee colonoscopy audit: North East Thames
(E Wood, JO Lindsay)
A randomised, single-blind comparison between a low volume
polyethylene glycol and ascorbic acid bowel preparation (Moviprep®)
and Picolax® in gut cleansing prior to colonoscopy
(J Worthington, M Thyssen, R Chapman)
GI PHYSIOLOGY
Poster round will be conducted by
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JNK MAPK and cPLA2 regulate chloride secretion in T84 colonic
epithelial cells (F Donnellan, BJ Harvey, FE Murray, SJ Keely)
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Diagnostic value of oesophageal physiology studies - an eight year
prospective study (S Mehta, R Lowndes, M Rhodes)
Assessment of rectal sensory and motor function using two different
barostat systems (SP Vasudevan, N Zarate, PJ Lunniss, SM Scott)
INFLAMMATORY BOWEL DISEASE
Poster round will be conducted by Dr SR Bloom and Dr C Mowat
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MTHFR polymorphisms are of pharmacogenetic value in azathioprine
treatment in inflammatory bowel disease (AR Ansari, M Arenas,
A Marinaki, J Duley, S Greenfield, C Lewis, J Sanderson)
Genomic DNA hypermethylation in colorectal mucosa of patients with
ulcerative colitis (The BORICC study) (RP Arasaradnam, K Khoo,
D Commane, M Bradburn, S Kelly, IT Johnson, JC Mathers)
Use and safety of infliximab for inflammatory bowel disease in South
East England (2):
predictors of response, safety and use of
immunosuppression in clinical practice (B Baburajan, M Parkes,
J Sanderson)
The pharmacogenetics of folate and purine metabolic pathways in
methotrexate therapy of inflammatory bowel disease (B Baburajan,
M Arenas, N Prescott, K Herrlinger, F Cummings, M Tremelling,
M Parkes, D Jewell, C Mathew, A Marinaki, J Sanderson)
HLA-G 14bp insertion-deletion polymorphism influences response to
methotrexate in inflammatory bowel disease (B Baburajan,
N Prescott,K Herrlinger, F Cummings, M Arenas, M Smith,
M Tremelling, A Ansari, M Parkes, D Jewell, C Mathew,
A Marinaki, J Sanderson)
Use and safety of infliximab for inflammatory bowel disease in South
East England (1) - adherence to recommended guidelines
(B Baburajan, G Bird, J Hunt, A McNair, A Ireland, I Bjarnson,
M Parkes,J Sanderson)
Polymorphisms in the peroxisome proliferator-activated receptor
gamma (PPAR-) gene are associated with ileal Crohn’s disease
(JB Beckly, L Hancock, A Geremia, DP Jewell)
Effect of anti-TNF antibodies on T lymphocyte cell cycle and
relationship to apoptosis (R Chaudhary, M Butler, S Ghosh)
Recent-onset Crohn’s disease shows higher remission rates and
durability of response to treatment with subcutaneous monthly
certolizumab pegol: results from an analysis of the PRECiSE 2 phase
III study (S Schreiber, JF Colombel, J Panes, J Scholmerich,
J McColm,W Sandborn)
Certolizumab pegol administered subcutaneously is effective in antiTNF naïve patients and in patients previously treated with infliximab
(S Hanauer, JF Colombel, W Sandborn, J Panes, J McColm,
S Schreiber)
Rapid induction of remission and clinical response with adalimumab in
patients with moderate to severe Crohn’s disease and secondary failure
to infliximab therapy: results of the GAIN study (J Columbel,
P Rutgeerts, WJ Sandborn, R Enns, SB Hanauer, JD Kent,
PF Pollack)
Leukocytapheresis for ulcerative colitis: correlation of clinical response
with immune regulation (F Cummings, BS Singh,
S Aryasingha, P Trzonkowski, SPL Travis, F Powrie, DP Jewell)
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Development validation and testing of a new social quality of life
measure for patients with inflammatory bowel disease (P Das,
S Gabe, JJ Smith, PP Tekkis, RJ Nicholls)
Effects of anti-TNF antibodies in vitro on dendritic cell apoptosis and
function (V Patel, M Butler, S Ghosh)
Poster round will be conducted by Dr J Satsangi and
Mr A Windsor
Incidence of Crohn's disease still rising in Cardiff: 1931-2005
(SK Gunesh, BA Hawthorne, GAO Thomas, GT Williams,
A Roberts)
Standard and alternative therapies for inflammatory bowel disease:– the
patient’s perspective (NC Hare, S Northey, C Pritchard,
LM Jackson, N P Michell)
The human ATP-binding cassete transporters superfamily and
xenobiotic-transcription regulators: analysis of intestinal epithelial gene
expression in inflammatory bowel disease (G Ho, C Noble,
J Cornelius, I Penman, I Arnott, L Diehl, J Satsangi)
The role of diet in the aetiology of ulcerative colitis - a European
prospective cohort study ( IBD in EPIC study investigators)
Infliximab for the treatment of ulcerative colitis: outcomes in Oxford
over a six year period (SL Jakobovits, T Ahmad, DP Jewell, SPL
Travis)
Validation of the new “PhiCal” faecal calprotectin test as a diagnostic
tool for pouchitis (MW Johnson, S Maestranzi, DH Dewar,
S McLaughlin, A Forbes, I Bjarnason, R Sherwood, PJ Ciclitira,
JR Nicholls)
Azathioprine induced hepatotoxicity in inflammatory bowel disease: is
it as rare as we think? (HE Johnson, TR Smith, SA Weaver)
MMX mesalazine is well tolerated during 12 months maintenance
treatment of mild-to-moderate ulcerative colitis (MA Kamm,
GR Lichtenstein, WJ Sandborn, K Barrett, RE Joseph)
Different definitions of remission for ulcerative colitis result in large
variations of clinical outcome scores (S Katz, S Kane, P Higgins,
B Yacyshyn, C Yeh)
The 7-nAChR receptor mediates inhibition by nictoine of TNF-
induced IL-8 production by HT29 colonic epithelial cells
(KM Khatab, W Dhaliwal, L Kruidenier, DS Rampton)
Randomised placebo-controlled trial of clarithromycin in active
Crohn’s disease (K Leiper, K Martin, A Ellis, AI Morris,
AJM Watson, JM Rhodes)
An assessment of bacterial dysbiosis in ileal pouch inflammation using
terminal restriction fragment length polymorphism
(MK Lim, J Adams, W Hutchinson, F Mzali, M Wilcox, S Gonsalves,
P Finan, P Sagar, D Burke)
A rapid non-invasive test for the qualitative detection of elevated faecal
lactoferrin in ileal pouch patients with inflammation (MK Lim,
S Gonsalves, D Thekkinkattil, P Sagar, P Finan, D Burke)
A comparative study of luminal and mucosal associated flora in
patients with ileal pouches (MK Lim, S Seedat, F Mzali, H Schuster,
M Wilcox , P Finan, P Sagar, D Burke)
Poster round will be conducted by Dr R Cowan and Dr F Muller
Satisfaction with healthcare in inflammatory bowel disease: influence
of patient characteristics (C Luces, E Brown, K Bodger)
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Alterations in the expression of human defensin-5 in ileostomy fluid of
patients with Crohn’s disease (DA Elphick, YR Mahida)
Effects of certolizumab pegol etanercept, adalimumab and infliximab
on lipopolysaccharide-induced cytokine production by human
peripheral blood monocytes (G Fossati, DT Brown, AM Nesbitt)
Antibodies to infliximab in patients with Crohn’s disease do not crossreact with certolizumab pegol (O Vetterlein, TM Kopotsha,
AM Nesbitt, DT Brown, S Stephens)
Accumulation of plasmacytoid dendritic cells in the intestine of acute
ulcerative colitis (SC Ng, S Plamondon, SC Knight, MA Kamm,
AJ Stagg)
Management of post-operative Crohn's disease in a specialist unit need for a defined strategy (SC Ng, N Arebi, MA Kamm)
Analysis of distinct genome wide expression proflies in the terminal
ileum of patients with Crohn’s disease (CL Noble, A Abbas,
J Cornelius, ID Penman, ID Arnott, Z Modrusan, K Toy, L Diehl,
J Satsangi)
Serum and salivary IgA responses to a 200kd saccharomyces cerevisiae
antigen in orofacial granulomatosis and Crohn’s disease
(C Nunes,P Shirlaw, M Mistry, D Rahman, M Escudier, JD
Sanderson,S J Challacombe)
The dietary management of orofacial granulomatosis (C Nunes,
MC Lomer, M Escudier, P Shirlaw, SJ Challacombe, JD Sanderson)
B-cell infiltrates in orofacial-granulomatosis (C Nunes, J Spencer,
M Escudier, P Shirlaw, G Parkes, L Petrovska, C Chinyama,
N Rayment, B Hudspith, MC Lomer, J Brostoff, E Odell,
SJ Challacombe, JD Sanderson)
High throughput 16S ribosomal RNA sequence analysis of the
intestinal microbiota in Crohn’s disease (L Petrovska, A Walker, C
Churcher, BN Hudspith, NB Rayment, GC Parkes, C Nunes,
J Brostoff, J Parkhill, G Dougan, JD Sanderson)
Molecular characterization of mucosal enterobactereriaceae isolated
from patients with inflammatory bowel disease (L Petrovska,
BN Hudspith, I Okeke, NB Rayment, GC Parkes, C Nunes,
J Brostoff, G Dougan, J Wain, DS Rampton, JD Sanderson)
Thalidomide in luminal and fistulising Crohn’s disease resistant to
standard therapies (S Plamondon, SC Ng, MA Kamm)
A non-synonymous SNP in an autophagy-related gene is associated
with Crohn’s disease (NJ Prescott, SA Fisher, A Franke, CM Onnie,
J Hampe, CE Todhunter, D Soars, J Sanderson, A Forbes,
J Mansfield, CM Lewis, S Schreiber, CG Mathew)
Poster round will be conducted by Dr T Orchard and
Dr B McKaig
A glycomic approach to the identification of disease biomarkers in
inflammatory bowel disease (P Roy, A Alavi, O Fraser, E Tarelli,
J Axford, D Kumar)
Endoscopically measured mucosal healing correlated with response to
therapy in moderately active ulcerative colitis (DT Rubin, BYacyshyn,
C Yeh, G Lichtenstein)
Diabetic control is not disturbed by an oral corticosteroid (prednisolone
metasulfobenzoate) designed to treat colitis (R Shah,
H Henderson, L Cartwright-Taylor, SR Gould)
Cyclosporine in acute ulcerative colitis: a retrospective review of a
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teaching hospital caseload over an eight-year period (G Singh,
D Greer,DM Chalmers, SM Everett, AT Axon, PJ Hamlin)
Myelotoxicity is a late event in azathioprine treated TPMT
heterozygotes: (MA Smith, AM Marinaki, M Arenas, S Greenfield,
A Ansari, JD Sanderson)
Serum protein signatures determined by mass spectrometry
(SELDI-TOF) accurately distinguishes Crohn’s disease from ulcerative
colitis (V Subramanian, D Subramanian, S Krishna,
M Farthing, R Pollok)
Infliximab therapy in Crohn's disease: current practice for future
guidelines (A Tewari, K Wise, M O'Connor, L Younge, N Arebi)
In situ hybridization for human defensins lysozyme, SPLA2 and
TNF- in Crohn's disease and controls (CE Todhunter, S Lala,
CG Mathew, JC Mansfield, S Keshav)
Confirmation of association between TNFSF15 and Crohn’s disease in
East Anglia panel (M Tremelling, S John, F Bredin, C Price,
M Parkes)
Germline variation of NOD1/CARD4 does not determine susceptibility
to inflammatory bowel disease: results of a detailed haplotype-tagging
investigation (JE Van Limbergen, ER Nimmo,
RK Russell, HE Drummond, NH Anderson, A Tenesa, CW Lees,
ID Arnott, DC Wilson, J Satsangi)
Azathioprine tolerance in inflammatory bowel disease: assess TPMT
status by phenotype or genotype? (JW Winter, D Gaffney, D Shapiro,
G Naismith, S Barclay, M Priest, S Dover, RJ Spooner, PR Mills)
LIVER
Poster round will be conducted by Dr R Jones and Dr M Hudson
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Recovery of liver function following decompensated alcoholic liver
disease: relation to subsequent drinking behaviour (A Ali,
E McFarlane, V Sakellariou, J Jones, D Gleeson)
Lactate alone is not an accurate predictor of poor prognosis in
paracetamol- induced fulminant liver failure (CM Bates, N Kochar,
JS Davidson, PC Hayes, KJ Simpson)
13C-methacetin breath test compared to non invasive biochemical
blood tests in predicting hepatic fibrosis and cirrhosis (C Sarrazin,
WF Caspary, C Dietrich, B Braden)
Haemochromatosis: rising hospital admission rates but stable mortality
1989/90 to 2002/03 (ML Cowan, S Westlake, A Majeed,
TM Rahman, JD Maxwell, J Kang)
Hepatitis E IGG seroprevalence in South West England
(HR Dalton, W Stableforth, E Cole, N Hamad, J Stephens, V Ellis,
H Hussaini, R Bendall)
Indigenous Hepatitis E – the Southampton experience (AN De Silva,
A Muddu, E Pelosi, N Sheron, J Iredale, S Khakoo)
Ultrasound guided versus ‘blind’ day case liver biopsy: what would you
choose? (KM Forrest, C Welch, D Mallon, H Smart,
I Gilmore, M Lombard)
Hepatitis C patients - the myth about poor DNA rates (M Rahman,
C Helmer, DA Gorard)
Long-term outcome of a cohort with autoimmune hepatitis at a single
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centre (B Höeroldt, D Gleeson, P Basumani, E McFarlane,
J Underwood)
Risks of mortality malignancy and myocardial infarction in people with
primary biliary cirrhosis: a population-based cohort study
(HR Jackson, M Solaymani-Dodaran, TR Card, GP Aithal, R Logan, J
West)
The risk of hepatocellular carcinoma and decompensation following
Hepatitis C treatment with interferon-based therapy (KM Jamil,
W Cheng, L Tarquinio, L Adams, L Mollison, G Macquillan,
J Flexman, B Deboer, N Kontorinis)
Management of depression in pateints treated with pegylated interferon
and ribavirin for Hepatitis C (KM Jamil, W Cheng,
L Tarquinio, L Allet, J Flexman, N Kontorinis)
Interferon induced thyroid dysfunction in chronic Hepatitis C
(KM Jamil, P Leedman, N Kontorinis, L Tarquinio, J Flexman,
V Burke, W Cheng)
Management of treatment failures in chronic Hepatitis C: does
retreatment succeed? (KM Jamil, W Cheng, L Tarquinio, J Flexman,
N Kontorinis)
Advanced fibrosis due to Hepatitis C: is antiviral treatment effective?
(KM Jamil, N Kontorinis, W Cheng, L Tarquinio, J Flexman)
Abnormal liver function tests and diabetes mellitus- a prevalence study
(D Kejariwal, L Scovell, K Freeman, K Dhatariya, M Phillips)
TIPSS in treatment of bleeding gastric varices – a large single centre
experience (N Kochar, D Tripathi, H Ireland, DN Redhead,
PC Hayes)
Chronic renal failure post liver transplant; prevalence and rate of
decline (JA Leithead, JW Ferguson, PC Hayes)
Minimal hepatic encephaopathy after TIPS insertion is associated with
a reduced quality of life (S Masson, HA Mardini, JD Rose,
CO Record)
Correlation of coronary artery calcification scores with features of the
metabolic syndrome in patients undergoing assessment for orthotopic
liver transplantation (NC McAvoy, PC Hayes, G McKillop)
Liver disease and Khat chewing in young Somalian men
(CA McCune, M Moorghen, FH Gordon, PL Collins)
The long-term prognosis of bleeding oesophageal varices – a 14 year
follow up study (LJ McLeman, J Thomson, D Armour, A Mowat,
A Fraser)
Non-transplant surgery for dominant stricture in primary sclerosing
cholangitis: revisited (MK Nayar, M Hudson, D Manas)
Portal biliopathy: a multidisciplinary approach to management
(YH Oo, S Olliff, G Haydon, D Thorburn)
Linear endoscopic ultrasound assessment and EUS-fine needle
aspiration of hilar lesions (M Nayar, D Manas, V Wadehra,
KN Oppong)
Prediction of outcome and complications after liver transplantation
using early non-invasive indocyanine green clearance: comparison with
conventional markers of graft function (AJ Portal, P Berry,
M Austin, JD Nolan, J Wendon, W Bernal)
Preliminary data of the role of chemoembolisation followed by
radiofrequency ablation in the treatment of multiple or large
hepatocellular carcinoma (N Rajoriya, J Crichton, M Neilson,
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E Leen, J Morris, E Forrest, A Stanley)
Bedside diagnosis of spontaneous bacterial peritonitis using urine
dipsticks (KA Rye, JG Freeman, AS Austin)
Acute renal failure in cirrhosis - is it as bad as we think? (KA Rye,
N Taylor, K Li, G Mortimore, M Johnson, AS Austin, JG Freeman)
Hospital readmission with decompensated alcoholic liver disease:
determinants, early outcome and accuracy of prognostic scores
(P Sakellariou, KL Bagguley, R Ferguson, J Kerss, E McFarlane,
D Gleeson)
An audit of the management of osteoporosis associated with chronic
liver disease (DA Sheridan, CE Macdonald)
Haematological malignancies presenting with acute liver failure: a
single centre experience (S Shetty, A Holt, W Syn, B Gunson,
G Haydon)
The role of small intestinal bacteria in disease initiation and
progression of non-alcoholic and alcoholic steatohepatitis (AR Smith,
JCM Paterson, JF Dillon)
Extraction of RNA from formalin-fixed, parraffin-embedded archival
hepatocellular carcinoma (PB Southern, F Lewis, P Quirke,
S Bennett, J Wyatt, CE Millson)
Alcohol awareness in medical undergraduates (N Sundar, E Colley,
N Blundell, R Alcolado)
Minimally-elevated liver function tests (LFTS) – are we seeing or
doing enough? (RC Thomas, D McClure, R Peaston, M Hudson)
Single nucleotide polymorphism of the SRB1 gene and susceptibility to
HCV infection (PH Thurairajah, D Hegazy, E Kaminski,
A Demaine, ME Cramp)
Percutaneous liver biopsies - does size matter? (CM Welch,
K Forrest, D Mallon, F Campbell, M Lombard)
Treatment of autoimmune hepatitis with mycophenolate moefitil
(MMP) (RH Westbrook, EE McFarlane, M Karajeh, D Gleeson)
NUTRITION
Poster round will be conducted by Dr I Fellows and
Dr J Woodward
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Acid-base problems during home parenteral nutrition
(P Chopra, J Groning, BJM Jones)
Clinical outcomes can be improved by increasing patient knowledge
with an information booklet (A Culkin, SM Gabe, A Madden)
Assessing the screening tests for malnutrition (C Somesundum,
X Andreou, CA Sabin, K Besherdas, N van Someren,
N Rajakumaraswamy, J Jocca, R D’Souza)
The nasal bridle – its place within an integrated nutrition service: a
prospective audit of one year’s data (E Donaldson, T Earley,
PL Shields)
“Pexact®" direct-puncture PEG placement: our first 12 months’
experience (H Gupta, R Manikandan, A Byrne, R Nicholson,
PA O'Toole)
MRSA in gastrostomy sites – prevalence, route of transmission and
relation to clinical infection and symptoms (BM Hall, M Ardenaso,
PJ Neild)
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Vitamin D levels in patients presenting to a gastroenterology clinic
(B Höeroldt, A Ali, M Shrinivas, P Basumani, P Willemse, R Ellis,
K Bardhan)
Referral for intestinal transplantation: an audit of intestinal failure
patients (D Lloyd, A Zabron, S Ralphs, J Woodward, N Jamieson,
S Middleton, S Gabe)
Fall in PEG insertion rate in Northern England following NCEPOD
(S Maitra, S White, A Torrance, K Matthewson)
A one-year retrospective audit of naso-jejunal tube placement
comparing endoscopically-placed versus radiologically-placed tubes:
do those placed with imaging at the time of insertion last longer?
(M McCarthy, A Ansari, A de Jabrun, M Small, R Salter,
T Sabharwal, J Sanderson)
PEG assessment team improves continuity of care for patients requiring
enteral nutrition in a district general hospital (K McKeown, VE Sayer,
AF Muller)
Experience from the nutritional support team at Belfast City Hospital
(GP Rafferty, S Lowry, K Robinson, D Kean, C Loughrey)
Gastrostomies in patients with dementia: kill or cure? (J Tharakan,
S Kaushik)
SMALL BOWEL
Poster round will be conducted by Dr M McAlindon and
Dr J Walters
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Specialist follow-up for people with coeliac disease - a questionnaire
study (EK Bridcut)
Adapting to life without gluten (EK Bridcut)
Response of reduced bone mineral density in coeliac disease to
treatment (D Comer, W Dickey)
Identification of patients with idiopathic bile acid malabsorption
presenting with chronic diarrhoea (RR Desai, IJ Tanswell,
A Sriharan, J Burdsall, R Ransford, MJ Hall)
Nutrient supplements prevent downregulation of intestinal defensin
expression during diarrhoeal disease (P Kelly, M Khanam, S Shawa,
I Zulu, A Tomkins, C Bevins, W Dhaliwal)
The changing presentation of coeliac disease in the North East of
England: an epidemiological analysis of four years (V Verma,
C Bloxham, A Dhar)
‘Hidden’ lactose in drugs may contribute to symptoms in patients with
gastrointestinal conditions and co-existing lactose sensitivity
(P Eadala, JP Waud, SB Matthews, JT Green, AK Campbell)
Monoclonal antibodies raised against high molecular weight glutenins
(HJ Ellis, S McLaughlin, DH Dewar, N Gonzalea-cinca,
I Van der Meer, H van den Broeck, H Wieser, C O'Sullivan
P Ciclitira)
Does tissue transglutaminase sensitivity increase with the severity of
villous atrophy in coeliac disease? (AD Hopper, DP Hulrstone, G Wild,
DS Sanders)
Malignancy and mortality in people with dermatitis herpetiformis: a
population-based cohort study (NR Lewis, RFA Logan, J West)
Fracture risk in people with dermatitis herpetiformis: a population-
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based cohort study (NR Lewis, RFA Logan, J West)
Capsule endoscopy for obscure gastrointestinal bleeding- analysis of
factors for a positive yield (R Sidhu, DS Sanders, K Kapur,
DP Hurlstone, JS Leeds, ME McAlindon)
Anaemia and osteoporosis in adult coeliac disease (IJ Tanswell,
R Desai, H Griffiths, E Horne, M Hall, R Ransford)
Persistent diarrhoea due to bacterial overgrowth in patients with midgut
carcinoid tumours (C Toumpanakis, K Jones, ME Caplin)
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