This Project Has Been Developed By Following Of IX STD from St.Joseph’s Higher Secondary School. 1.SATHISH KUMAR.T 2.PRAVEEN KUMAR.S 3.DAYANITHI.S 4.DEVARAJ.S 5.MANIKANDAN.R students Introduction Life Sciences in the 21st Century: Biotechnology What is biotechnology? The use of technologies based on living systems (plants, animals, or microbes) to develop commercial processes and products or improve existing species Biotechnology for the 21st Century SCIENCE INSTRUMENTS is a leading supplier of training equipment in a number of areas and is one of our newest suppliers. They developed an innovative new instructional series for medical and biotech training. Science Instrument was founded by Mr. Morris Tischler, the inventor of the solid-state pacemaker. He has used his outstanding experience in the medical industry to develop these courses of study for K-12. In this issue we are reviewing the High School Programs. The Challenge of Biotechnology The age of biotechnology has arrived. For the first time in human history it is possible to completely redesign existing organisms, including man, and to direct the genetic and reproductive constitution of every living thing. Scientists are no longer limited to breeding and cross-pollination. Powerful genetic tools allow us to change genetic structure at the microscopic level and bypass the normal processes of reproduction http://www.fortune.com/sitelets/sections/fortune/tech/2001_04biotech.html Technology Technology Biotechnology Innovative companies shaping the 21st century Usually, historical eras are defined by accomplishments analyzed with the benefit of contextual hindsight. But the first 100 years of our new millennium will most certainly be a notable exception. This period is being defined as the Biotech Century, based on the prospect of extraordinary improvements in human health and well-being. http://www.bioweb.ne.jp/jsbba/pic/kouken_e.jpg Crop Research Challenges Agricultural researchers and farmers worldwide face the challenge during the next 25 years of developing and applying technology that can increase the Global cereal yields by 50-75 percent, and to do so in ways that are economically and environmentally sustainable. Much of the yield gains will come from applying technology "already on the shelf" but yet to be fully utilized. But there will also be new research breakthrough, especially in plant breeding to improve yield stability and hopefully maximum Genetic yield potential. Biotechnology is a set of powerful tools that employ living organisms (or parts of organisms) to make or modify products, improve plants or animals, or develop microorganisms for specific uses. Examples of the "new biotechnology" include the industrial use of recombinant DNA, cell fusion, novel bioprocessing techniques, and bioremediation. http://www.bioweb.ne.jp/jsbba/pic/kouken_e.jpg Disadvantages of biotechnology Bio technology can do good, but it also has the potential to do great harm. In the wrong hands, genetic engineering could be used to create an increasingly complex set of pathogens targeted at humans, Plants or animals. The popular press is full of such stories and Richard Preston's The Cobra Event is particularly compelling. Although we cannot predict the exact course that biotechnology will take, we can predict that some people will try to use any future advances malevolently. Thus, an unceasing effort has been mandated to develop defensive tools or preventative measures against the use of biotechnology in the making of weapons. In the USA, this issue is already the target of a major research program, 'Unconventional Pathogen Countermeasures', which is funded by the Defense Advanced Research Projects Agency http://www.genethik.de/biotechnology.htm Advanced Research Projects Agency Technology inventor J. Dean Barry J. Dean Barry is the Chief Executive Officer of 21st Century Medicine, . He manages the strategic focus of the company’s highly specialized research projects and is responsible for business development. Mr. Barry brings to the company more than 25 years of successful biotechnology management experience with a history of team building and creating cooperative strategic alliances. Most recently the President and CEO of VRL, Inc. & Viratest International, Inc. in San Antonio, Texas, Mr. Barry maximized assets, leveraged the companies’ strengths and created value from scarce resources while preparing these companies for strategic acquisition. Previously, Mr. Barry was the General Manager of Southwest Bio-Clinical Laboratories, Inc. He began his career at Medinco, Inc., initially as a Laboratory Manager, then moved up to Regional Director and eventually became Director of Diagnostic Services. A native of Pennsylvania, Mr. Barry holds dual Bachelor’s degrees in Microbiology and Social Psychology and a Master’s degree in Medical Microbiology from the Penn State University. Mr. Barry is a published author and has several U.S. patents. (http://www.darpa.mil/dso/rd.upc) Genetic modification Genetic Modification of Food, the alteration of the genome of plants grown for food in order to produce crops with specific advantages such as resistance to pests. Genetic Modification in crops In genetic modification, scientists use restriction enzymes to isolate a segment of DNA that contains a particular gene of interest (1). In this instance, it is a human gene. A plasmid extracted from its bacteria and treated with the same restriction enzyme can hybridize with this fragment’s “sticky” ends of complementary DNA (2). The hybrid plasmid is reincorporated into the bacterial cell, where it replicates as part of the cell’s DNA (3). A large number of daughter cells can be cultured and their gene products extracted Advantages of genetic modification There are potential advantages of genetically modified crops for three groups of people: (i) Growers, who will benefit from the resistance of crops to insect pests and fungi, by the introduction of natural insecticides or fungicides from other species, so reducing the need for application of agricultural chemicals, hence also an environmental gain; resistance to herbicides, (ii) Food processors and manufacturers, who will benefit from produce with a longer shelf-life, and better properties for processing, manufacture, and so on. . iii) Consumers, who will have cheaper and more plentiful food as a result of the advantages to growers and processors. Future impacts: Biopharmaceutical Products Similarly, transfer or substitution of genes from one species to another offers the opportunity to create species capable of producing desired biopharmaceutical products in greater amounts or at substantially lower cost, eg pharmaceuticals manufactured by bacteria or plants, human protein products from the milk of animals. Effects of Biotechnology on Agricultural Chemical Use Biotechnology has the potential to reduce the application of agricultural chemicals for pest control and fertilization through the utilization of genetically modified micro organisms, plants, and animals. Insecticidalplantproteins Through the use of biotechnology, scientists have developed plants that produce a naturally occurring protein that is toxic to certain cropdamaging insects. The most common examples are the "Bt" plants, which include corn, cotton, and potatoes. These genetically engineered plants produce a protein normally found in the soil bacterium, Bacillus thuringiensis (Bt). Commercial sprays that contain Bacillus thuringiensis have been available for decades as an alternative to chemical insecticides. The Bt protein is toxic to certain crop-damaging insects, but is harmless to humans. Researchers are also searching for other insecticidal and antimicrobial proteins that are appropriate for use in crops. http://www.ext.vt.edu/pubs/biotech/443-005/443-005.html THANKS FOR VIEWING OUR PROJECT