Hamari Chemicals, Ltd.
The CV of Hiroki Moriwaki
Page 1/4
Hiroki Moriwaki
Birth date:
03/04/1961
Nationality:
Japan
Resides:
1-18-27 Hanazonohigashi-machi, Higashiosaka-city, Osaka, Japan 578-0931
Mobile Phone Number: 090-2100-2496
Home Phone Number:
072-964-0621
Email: hiroki-moriwaki@hamari.co.jp

Education:
1985

Kyoto Pharmaceutical University
Qualifications:
Pharmacist

1985
Work Experience
1985 - Present
Hamari Chemicals, Ltd.
Director,
Osaka, Japan
Research & Development Department
April, 1985 – March, 1991
Technical section, Manufacturing Dep., Takathuki Plant
April, 1991 – March, 1992
Chemical section, Research & Development Dept
April, 1992 – March, 1994
Dispatch, Kyoto Pharmaceutical University
Prof. Yoshiaki Kiso , Medicinal Chemistry
I studied the process chemistry such as peptide synthesis and
HIV protease inhibitor.
April, 1994
return to work, Chemical section, Research & Development
Dept.

August,1997
Manager, Chemical section, Research & Development Dept.
August, 2000
Assistant Director, Research & Development Department
August, 2006
Director, Research & Development Department
Special field
Process Chemistry and Peptide Synthesis
Process Chemistry: More than 60 reactions on commercial scale such as Negishi and Suzuki
reaction, reductive amination using metal catalysts, and Indoles and Quinolines using Nitration
Peptide Synthesis: Expertise technology using solution phase synthesis such as ACE inhibitor,
intermediate of anti-cancer drugs and LH-RH-analogues.
This document contains confidential information. Please don’t distribute outside of your organization without consent of Hamari Chemicals.
Hamari Chemicals, Ltd.
1-4-29, Kunijima, Higashi-Yodogawa-ku, Osaka, Japan, 533-0024 TEL +81-6-6322-0191 FAX +81-6-6326-6744
Hamari Chemicals, Ltd.
The CV of Hiroki Moriwaki
Page 2/4
1.
Oral presentation
October, 1984
The Pharmaceutical Society of Japan
Kinki branch office general meeting
(Synthesis and application of imidazole derivatives)
July, 2004
The Japanese Society for Process Chemistry (JSPC)
Summer Symposium
2004
(Process developments of L-carnosine derivatives)
October, 2004
Osaka Industrial Research Association
Seminar
(Development and a process Chemistry for the peptide-based useful
material)
2.
Papers
Moriwaki, Hiroki; Nakagami, Yuichi.
High quality of alpha-lipoic acid. Process development and manufacturing.
Fragrance Journal (2005), 33(8), 68-74.
Kimura, Tooru; Ohtake, Jun; Nakata, Shingo; Enomoto, Hiroshi; Moriwaki, Hiroki; Akaji, Kenichi;
Kiso, Yoshiaki.
Synthesis of prodrugs of HIV protease inhibitors.
Peptide Chemistry (1995), Volume Date 1994, 32nd 157-60.
Ohta, Shunsaku; Hayakawa, Satoshi; Moriwaki, Hiroki; Harada, Suzumi; Okamoto, Masao.
Synthesis and application of imidazole derivatives.
Synthesis and acyl activation of 2-acyl-1-methyl-1H-imidazoles.
Chemical & Pharmaceutical Bulletin (1986), 34(12), 4916-26.
Ohta, Shunsaku; Hayakawa, Satoshi; Moriwaki, Hiroki; Tsuboi, Shinichi; Okamoto, Masao.
Synthesis of 2-acyl-1-methyl-1H-imidazoles and reactivity of the acyl group.
Heterocycles (1985), 23(7), 1759-64.
This document contains confidential information. Please don’t distribute outside of your organization without consent of Hamari Chemicals.
Hamari Chemicals, Ltd.
1-4-29, Kunijima, Higashi-Yodogawa-ku, Osaka, Japan, 533-0024 TEL +81-6-6322-0191 FAX +81-6-6326-6744
Hamari Chemicals, Ltd.
The CV of Hiroki Moriwaki
Page 3/4
3. Patent
Ando, Kazuo; Shishido, Masahiko; Moriwaki, Hiroki.
Method for preparing 2E,6E-isomer-enriched farnesal via alkali metal bisulfite adducts.
Jpn. Kokai Tokkyo Koho (2008), JP 2008201736
Shishido, Masahiko; Ueno, Koichi; Nakagami, Yuichi; Moriwaki, Hiroki.
Preparation of high-purity  -lipoic acid L-ornithine salt.
Jpn. Kokai Tokkyo Koho (2008), JP 2008156282
Terasawa, Michio; Kanetani, Eiko; Moriwaki, Hiroki.
Degranulation inhibitors containing histidine-containing dipeptide.
Jpn. Kokai Tokkyo Koho (2008), JP 2008031066
Shishido, Masahiko; Ueno, Koichi; Nakagami, Yuichi; Moriwaki, Hiroki.
Method for preparation of  -lipoic acid L-lysine salt crystal.
Jpn. Kokai Tokkyo Koho (2008), JP 2008156281
Shishido, Masahiko; Nakagami, Yuichi; Moriwaki, Hiroki; Ishino, Yoshio; Mizuno, Takumi; Iwai,
Toshiyuki.
Preparation of crystalline  -lipoic acid L-lysine salt.
Jpn. Kokai Tokkyo Koho (2007), JP 2007070238
Moriwaki, Hiroki; Nakagami, Yuichi; Nakayama, Keiso; Sawamura, Yoshihito; Takami, Tokio.
Preparation of water-soluble  -lipoic acid amino acid salts.
Jpn. Kokai Tokkyo Koho (2006), JP 2006265202
Yamaoka, Nagatoshi; Egawa, Hiroshi; Takenaka, Shigekazu; Moriwaki, Hiroki.
Preparation of carnosine.
Jpn. Kokai Tokkyo Koho (2005), JP 2005306782
Hiraoka, Katsuyuki; Moriwaki, Hiroki.
Preparation of L-anserine from phthalyl-L-carnosine.
Jpn. Kokai Tokkyo Koho (2005), JP 2005082571
Takahashi, Motohiro; Watanabe, Teruo; Murayama, Shuichi; Moriwaki, Hiroki.
Preparation of optically active phenylpropionic acids.
Jpn. Kokai Tokkyo Koho (2000), JP 2000309557
This document contains confidential information. Please don’t distribute outside of your organization without consent of Hamari Chemicals.
Hamari Chemicals, Ltd.
1-4-29, Kunijima, Higashi-Yodogawa-ku, Osaka, Japan, 533-0024 TEL +81-6-6322-0191 FAX +81-6-6326-6744
Hamari Chemicals, Ltd.
The CV of Hiroki Moriwaki
Page 4/4
Kimura, Tooru; Moriwaki, Hiroki; Kiso, Yoshiaki.
Preparation of tripeptides with improved water solubility as prodrugs for HIV protease inhibitors.
Jpn. Kokai Tokkyo Koho (1996),
JP 08109180
Maeda, Sadayuki; Moriwaki, Hiroki; Mitsumoto, Tsutomu; Kisanuki, Junji; Kato, Ryohei; Maeda, Hiroshi;
Takahashi, Osamu; Kiso, Yoshiaki.
preparation of peptides derivatives as intermediates for HIV protease inhibitors.
Jpn. Kokai Tokkyo Koho (1994),
JP 06220031
This document contains confidential information. Please don’t distribute outside of your organization without consent of Hamari Chemicals.
Hamari Chemicals, Ltd.
1-4-29, Kunijima, Higashi-Yodogawa-ku, Osaka, Japan, 533-0024 TEL +81-6-6322-0191 FAX +81-6-6326-6744