Original Articles Reports of original investigations in refereed journals. 1. 2. 3. 4. 5. 6. Nielsen S, Miravalle A, Langer-Gould A, Cooper J, Edwards K, Kinkel P. B cell depletion and safety of low dose rituximab in patients with relapsing multiple sclerosis. Mult Scler 2012; 18: 377-378. Edwards K, Goodman W. Improvement of neuropsychological function in cognitively impaired multiple sclerosis treated with natalizumab. Int. J MS Care 2012; 14:100104 Edwards K, Rosenthal B, Farmer K et all. Evaluation of Sumatriptan-Naproxen in the treatment of acute migraine headache. Headache 2012; 53:656-664 Edwards K, Cadavid D, Ranger A et all. Feasibility study of the Use of Combinatorial Chemokine Arrays to study blood and CSF in MS. PLoS One 2013, 8:e81007 Fox E, Edwards K, Burch JG, Wynn D et al Outcomes of Switching Directly to Oral Fingolimod from Injectable Therapies: Results of the Evaluate Patient OutComes (EPOC) Study in Relapsing Multiple Sclerosis. In Press Mult Sclerosis and Related Disorders Edwards K, Cree B, Crayton H, Kantor D, et al. Change from baseline in PROs (TSQM, FSS, BDI-II) and CGI-I in previously treated Interferon and glatiramer patients switching to Gilenya vs staying on interferons or glatiramer. In preparation Calkwood J, Cree B, Edwards K et al Impact of a switch to fingolimod versus staying on glatiramer acetate or beta interferons on patient- and physician-reported outcomes in relapsing MS: post hoc analysis of the EPOC trial. In press Proceedings of Meetings Published full length articles of meeting presentations for which papers were selected and which contain new data. Poster and Platform Presentations, National and International Meetings: (2011Present) 1. 2. 3. 4. February 15-20, 2011 “The level of CXCL13 correlates with a B cell and plasma cell transcription signature in the cerebrospinal fluid of secondary progressive multiple sclerosis patients”. (Platform Presentation). Presented at the Keystone Symposia on Molecular and Cellular Biology in Taos, New Mexico. April 9-April 16, 2011 “Evaluation of Sumatriptan-Naproxen in the Treatment of Acute Migraine Headache: A Placebo Controlled, Double Blind, Crossover Study accessing Cognitive Function”. (Poster Presentation). Presented at the 63rd American Academy of Neurology (AAN) in Honolulu, Hawaii. April 9-April 16, 2011 “Capture of Patient-Perceived Negative Mood Traits to Omprove Treatment for Patients with Multiple Sclerosis”. (Poster Presentation). Presented at the 63rd American Academy of Neurology (AAN) in Honolulu, Hawaii April 9-April 16, 2011 “Decrease in Individual Multiple Sclerosis Severity scores during follow-up Period: Analysis of the New York State Multiple Sclerosis Consortium 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. Dataset”. (Poster Presentation). Presented at the 63rd American Academy of Neurology (AAN) in Honolulu, Hawaii April 9-April 16, 2011 “Pregnancy related to disability outcomes for women with progressive multiple sclerosis”. (Poster Presentation). Presented at the 63rd American Academy of Neurology (AAN) in Honolulu, Hawaii April 13, 2011 “CSF levels of secondary lymphoid organ chemokines are elevated in relapsing–remitting multiple sclerosis and secondary progressive multiple sclerosis and worsen during acute exacerbations” (Platform Presentation). Presented at the 63rd American Academy of Neurology (AAN) in Honolulu, Hawaii June 2-5, 2011 “Cognitive Dysfunction at Onset of Acute Migraine” Presented at the 53rd Annual Scientific Meeting for the American Headache Society Washington, DC. June 2-5, 2011 “An Evaluation of Sumatriptan-Naproxen (Treximet) in the treatment of Acute Migraine Headache: A Placebo controlled, double blind, crossover study accessing cognitive function.” Presented at the 53rd Annual Scientific Meeting for the American Headache Society Washington, DC. April 21-April 28, 2012 “Natalizumab use for neuropsychological deficits in relapsing multiple sclerosis”. (Poster Presentation). Presented at the 64th American Academy of Neurology (AAN) in New Orleans, LA. May 29 -June 1, 2013 “Treatment satisfaction and clinical improvement after switch to fingolimod”. (Poster Presentation). Presented at the 27th Annual Meeting of the CMSC and the 5 th Cooperative Meeting of CMSC-ACTRIMS, Orlando, Florida June 8-11, 2013 “Treatment satisfaction and clinical improvement after switch to fingolimod”. (Poster Presentation). Presented at the 23rd Meeting of the European Neurological Society in Barcelona, Spain October 2-5, 2013 “Patient- and physician-reported outcomes after therapy switch from interferon beta to fingolimod versus staying on interferon beta therapy” (Poster Presentation) - Accepted at the 29th congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and the 18th Annual Conference of rehabilitation in MS (RIMS), Copenhagen, Denmark April 26 – May 3, 2014 “ Safety of Using Disease-modifying Therapy Postalemtuzumab Treatment in Patients with Relapsing-remitting Multiple Sclerosis in the Core and Extension Phases of CAMMS223, CARE-MS I, and CARE-MS II studies” (Poster Session II) Accepted at the American Academy of Neurology 66th Annual Meeting in Philadelphia, PA April 26- May 3, 2014 “ Treatment Satisfaction after Switching to Fingolimod directly from an injectable therapy” (Poster Session VII) Accepted at the American Academy of Neurology 66th Annual Meeting in Philadelphia, PA May 28-June2, 2014 “Switching from Natalizumab to Teriflunomide in Multiple Sclerosis Patients Who Have Received Natalizumab for More Than 12 Months” (Poster session ) Accepted at the 6th Cooperative Meeting of CMSC-ACTRIMS, Dallas, Tx May 28-June 2, 2014 “Patient and Physician Reported Outcomes after Therapy Switch from Interferons or Glatiramer Acetate to Fingolimod” (Poster session ) Accepted at the 6th Cooperative Meeting of CMSC-ACTRIMS, Dallas, Tx September 10-13, 2014 “Teri-Pro: Study Design and US Patients Baseline Characteristics” - Accepted at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Boston, MA