Partners Research Studies Seeking Volunteers
Healthy Volunteer Studies
1. An fMRI Study of the Modulation of Cognition by Emotion
Have you never been diagnosed with a psychiatric disorder?
Do you not have any metal in your body (e.g., heart pacemakers, aneurysm clips, or other
metallic objects)?
In case you answered these questions with 'yes', you might be eligible to participate in a
study at the Massachusetts General Hospital (MGI-I)/Harvard Medical School. The entire
study will not take longer than 2.5 hours to complete, and you will receive $100 dollars
for the completion of the study. Specifically, the study will involve a brief interview,
filling out questionnaires, and completing some tasks while "pictures" of your brain are
taken using functional Magnetic Resonance Imaging (fMRI). Only individuals without
pacemakers, aneurysm clips, or other metallic objects in the head and upper body are
eligible for fMRI.
If you are interested in participating or would like to get further information, please call
Lindsay at 617-643-5129 at the Massachusetts General Hospital (MGH), Psychiatric
Neuroscience Program, or email her at lcarlson2@partners.org
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1750
2. Neural Correlates of Behavior Therapy in Tourette's Syndrome
Normal Control Subjects Wanted for A Study Of Brain Function in People Who Suffer
From Tourette's Syndrome
Dr. Thilo Deckersbach of the Psychiatry Department at the Massachusetts General
Hospital is conducting a research study to examine brain function in people who suffer
from Tourette's Syndrome, as compared with those who do not.
The entire study will consist of 2 study visits that will each take approximately 2 - 2 ½
hours and will involve a clinical evaluation, filling out questionnaires, and completing
cognitive tasks while "pictures" of your brain are taken using functional Magnetic
Resonance Imaging (MRI). Only individuals without pacemakers, aneurysm clips, or
other metallic objects in the head and upper body are eligible for MRI. Participants will
be paid $100 for each study visit and will be provided with a parking pass if they park at
the MGH-Charlestown Navy Yard parking garage.
If you are between the ages of 18-64, are without any psychiatric disorders, and are
interested in this study, please contact Lindsay at 617-643-5129 or email
lcarlson2@partners.org.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1749
Posted 9/17/08
3. Do you have ACNE ON YOUR BACK?
You may qualify for a research study of a birth control pill versus placebo (placebo
contains no active medication).
If you are Female and 18-45 years old
Desire birth control
6 study visits over 24 weeks
Must use other form of birth control during study
Up to $300 in compensation for time and travel
For more information, please e-mail harvardskinstudies@partners.org or call (617) 7265066
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000285
4. Do You Have Dandruff
Do You Have Dandruff
You may qualify for a research study of an approved foam medication in Seborrheic
Dermatitis
If you are 12 years or older
7 study visits over 52 weeks
Compensation Available
For more information please call (617) 726-5066 or e-mail
harvardskinstudies@partners.org
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000284
5. Laboratory Evaluation of Neuropathic Pain
Are you healthy and between 40 and 49 years old?
We seek men and women to participate as healthy controls (comparison group) for a
diabetes research study. You must have never had diabetes. This study involves a single
visit to the Mass General hospital during which you will have a glucose tolerance test to
screen for diabetes. Recent normal results of this test can be used instead. You will also
have two small punch skin biopsies removed from your lower leg under local anesthesia.
Payment for participation is offered. For more information, please contact Heather
Downs of the MGH Neurology Department at 617-726-0260 (HDowns@partners.org).
IRB#99-9042
Posted 9/17/08
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000302
6. Magnetic Resonance Spectroscopy in Children at Risk for Mood Disorders
We are looking for healthy families, with youth ages 6-24 years, and their parents who do
not have a history of mood disorders, to participate in a neuroimaging study. This study
looks at differences in brain chemicals among youth at higher and lower risk for bipolar
disorder. Both parental and youth involvement is necessary.
We are interested in making sure that we have balanced representation of African
American, Asian American and Latino families in our sample, so that our findings may
help us learn about the community at large.
The study offers:
. Two brain scans (an MRI and an MRS scan) at no cost
. An evaluation of emotional and behavioral functioning
. An evaluation of intellectual strengths and weaknesses
. Monetary compensation for each assessment
. No treatment is provided in this study
For more information, contact Caroline at (617) 503-1411.
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000299
7. Magnetic Resonance Spectroscopy in Children at Risk for Bipolar Disorder
Do you have frequent mood swings? Do you go through times when you feel "too good,"
overly excited or confident, overly active, or unusually irritable? Have you ever been
diagnosed with mania or bipolar disorder? Do you have a child age 6-17 years? If so, we
would welcome your participation in our neuroimaging research study. This study looks
at differences in brain chemicals among children who have a parent with bipolar disorder.
We are interested in making sure that we have balanced representation of African
American, Asian American and Latino families in our sample, so that our findings may
help us learn about the community at large.
The study offers:
. Two brain scans (an MRI and an MRS scan) of your child at no cost
. An evaluation of your and your child's emotional and behavioral functioning
. An evaluation of your child's intellectual strengths and weaknesses
. Monetary compensation for you or your child for each assessment
. No treatment is provided in this study
Participation involves 2-3 study visits, each lasting 2-5 hours.
For more information, contact Caroline at (617) 503-1411.
Posted 9/17/08
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000239
8. Subclinical Atherosclerosis in HIV Infected Men
Healthy Male Volunteers Wanted
.. 40-46 years old
You may be eligible for a research study examining heart disease risk at the
Massachusetts General Hospital (MGH).
Study involves:
.. 2 visits at the MGH Clinical Research Center
.. CT scan of the heart
Subjects receive a comprehensive evaluation and up to a $100 payment for two outpatient
visits.
Please contact Jeffrey Wei at (617) 724-8070.
MGH Program in Nutritional Metabolism
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000287
9. Risk Factors for Adverse Outcomes in Young Offspring of Bipolar Children
Do you have a child age 2-5 years?
If so, and if neither you nor your child's other parent has a history of depression or mood
disorder, we would welcome your participation in our research study at the
Massachusetts General Hospital, funded by the National Institutes of Health. We are
looking at whether childhood behavioral characteristics can predict later behavior.
The study offers:
. Yearly diagnostic screenings at no cost
. A detailed behavioral and cognitive evaluation
of your child (and his/her older siblings) one year from
the initial assessment at 4, 5, or 6 years of age.
. Monetary compensation for you or your child for each assessment
For more information, contact Marisa at (617) 503-1409 or see our web site at
www.massgeneral.org/pediatricpsych. See the study "Risk Factors for Adverse Outcome
in Young Offspring of Bipolar Parents."
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000277
10. Developing a Workplace Laboratory for Adults with Attention Deficit
Hyperactivity Disorder
Posted 9/17/08
Volunteers (18-55 years old) with and without ADHD are invited to participate in a study
investigating how adults with ADHD function while performing tasks similar to those
encountered in the workplace. This study will take up to 16 hours. This time is divided
between the initial visit to obtain consent and complete up to 5 hours of testing, and one
work simulation day lasting from 8:30 am to 7:00 pm. Subjects may be compensated up
to $350. Please contact the study coordinator at (617) 724-8485 or kclaudat@partners.org
for more information.
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000275
11. Biochemical Changes Correlated with the Antidepressant Treatment of
Escitalopram
Have you been feeling depressed or down? Do you no longer enjoy the things you used
to? Have you been having trouble falling asleep or staying asleep?
If you've answered yes to any of these questions, you could be eligible for a research
study at Massachusetts General Hospital. This study is looking for participants between
the ages of 18 and 65 who are depressed and not currently taking any medication. If
eligible, participants would be put on the FDA approved antidepressant medication
Escitalopram (Lexapro). As part of this study there would be three Magnetic Resonance
Spectroscopy (MRS) scans over the course of 13 weeks. These brain imaging scans
measure the concentrations of several compounds in the brain. These scans would take
place at Mclean Hospital in Belmont, MA and participants will be offered $100
compensation for the first and last scan, $50 for the second, shorter scan, as well as $25
per scan to cover transportation costs to Mclean Hospital. At the end of the study
participants will be offered three months of follow up care at no cost.
For more information contact Vicki at 617-724-9458 or vameral@partners.org
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1725
12. Behavioral, Structural, and Functional Effects of Meditation
Healthy volunteers needed to participate in a neuro-imaging study on brain function.
Participate and receive a fMRI scanned picture of your brain!!!! (note: not a diagnostic
image but looks great on your refrigerator)
Study requires 4.5 to 5 hours of your time at the neuro-imaging lab at Mass-General
Hospital, Charlestown, in addition to on-line questionnaires.
Participants must:
be between the ages of 40 and 70
have no yoga or meditation experience
be a non-smoker
not be taking medication for a psychological/psychiatric condition
Posted 9/17/08
Participants will also be compensated $100 for their time
If interested, please contact: lazar-lab@nmr.mgh.harvard.edu, or call: 617-724-2256
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000273
13. Evaluation of Digital Subtraction Bowel Cleansing and Automated Polyp
Detection in CT Colonography (Virtual Colonoscopy)
Do you have a Colonoscopy appointment?
Seeking volunteers for a research study evaluating Virtual Colonoscopy
using a laxative-free bowel preparation
Description: CT colonography (Virtual Colonoscopy) consists of a low X-ray dose CAT
scan, which is performed after gently filling the colon with carbon dioxide. The images of
the colon are reconstructed into a computer model, which allows for a minimallyinvasive screening of the colon for abnormalities such as polyps and masses. Instead of
drinking a laxative to empty the bowel prior to the colon test, study participants drink a
contrast solution during the laxative-free bowel preparation. The contrast solution allows
for the computer model of the bowel to be cleansed electronically. Thus, the laxative-free
bowel preparation regimen is intended to be more comfortable for patients than current
bowel preparations.
You may be eligible to participate in the research study if you:
1. Are 50-80 years old
2. Have a Colonoscopy scheduled at Massachusetts General Hospital, Brigham and
Women's Hospital, Newton Wellesley Hospital, or North Shore Medical Center
3. Have a Colonoscopy scheduled either for routine colon screening or because of a
family history of colon cancer or a change in bowel habits.
4. Have not had a Colonoscopy or Sigmoidoscopy in the past 5 years
The standard colonoscopy is REQUIRED for inclusion in the study, as part of a reference
standard comparison.
Participants in this research study:
1. Must be available for two study visits at an MGH location: a 30 minute information
visit and a 30 minute CT Colonography test (total duration of second visit: 1hour).
2. Will be asked to follow a low fiber diet as well as drink a small amount of contrast
solution with meals and snacks for the two days prior to the second visit
(i.e., prior to the CT colonography).
3. Will receive study related laxative-free bowel prep and CT Colonography test at no
cost.
4. Must undergo Colonoscopy between 1-4 weeks after the CT Colonography test.
(The cost of the Colonoscopy is not covered by the study.)
Posted 9/17/08
Participants will receive free parking for the two study visits, plus a $70 payment for
participation upon completing all study requirements.
Interested individuals or their physicians should contact Dr. Michael Zalis
via phone 617-724-2628 or e-mail: mzalis@partners.org. Please state in your call that
you are responding to this letter.
Thank you for your time and interest in clinical research.
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000271
14. hCAP18 and Vitamin D deficiency in Healthy Subjects
RESEARCH STUDY NOTICE
Healthy Volunteers Wanted
For a research study on
Vitamin D Deficiency and Immune Defense
Vitamin D deficiency is a common problem in the Boston area. Most people with
Vitamin D deficiency do not know they have it.
We are looking for healthy volunteers, ages 18-80, to participate in a research study of
vitamin D and the immune system. We will check blood levels of vitamin D levels and a
protein involved in immune defense.
Participants found to be vitamin D deficient will be offered vitamin D supplements and
return in two weeks for repeat levels.
There will be no cost to anyone who participates. No investigational drugs will be used.
All individuals welcome. Women and minorities are encouraged to participate.
For more information, contact Dorrie Sullivan, RN at dsullivan18@partners.org or 617726-5382.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1719
15. Metabolic Alterations in Women with a History of Hypertensive Disorders of
Pregnancy
MOMS
MGH Obstetrical Maternal Research Study
Did you have a baby at MGH within the past three years?
Posted 9/17/08
If so, consider becoming a part of MOMS, the MGH Obstetrical Maternal Study. Being a
part of this research study will help the medical community understand why women who
develop high blood pressure or high blood sugar during pregnancy are at increased risk of
developing high blood pressure or high blood sugar later in life.
This research study involves one 3-4 hour visit to the Clinical Research Center at MIT,
and includes fasting blood and urine tests, an oral glucose tolerance test, and timed blood
tests. Your participation will help us reach our goal of understanding and treating this
condition. You will be paid $150 for participating in this research study.
For more information, or to schedule a visit, please contact Dorrie Sullivan, RN at 617726-5382
Or DSullivan18@partners.org
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1717
16. Electroencephalogram Studies of Induction and Recovery from Propofol
Induced General Anesthesia
The Mass General Hospital Department of Anesthesia and Critical Care is recruiting
healthy, non-smoking adults, ages 18-36 years for a research study to identify the sites of
action of propofol anesthesia in the brain. We will be using magnetic resonance imaging
(MRI) and electroencephalogram (EEG) to observe brain activity. Studies will be
conducted at the MGH General Clinical Research Center in the Charlestown Navy Yard,
and will consist of a physical exam and a 7-hour imaging/EEG/anesthesia session. Two
or three visits will be required to complete the study. Subjects will receive up to $200 for
completion of the study. For more information, please contact Dr. Emery N. Brown in the
MGH Department of Anesthesia and Critical Care at 617-724-9857 or at
mgh.anesthesia.study@gmail.com http://neurostat.mgh.harvard.edu/anesthesia_eeg.htm.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1704
17. General Pre-Trial Screening Protocol for Enrollment of Volunteers into Vaccine
Research Protocols.
Healthy Volunteers Wanted for HIV Vaccine Research Study
Brigham and Women's Hospital researchers are looking for healthy men and women to
participate in HIV Research Studies.
You may be eligible to participate in one of the investigational, preventive studies
currently being conducted, if you meet the following criteria:
- HIV negative adult
- 18-50 years in age
- In good health
All participants receive counseling and testing at no cost. Compensation is also provided.
Posted 9/17/08
FACT: You cannot get HIV from parcipating in an HIV Vaccine Research Study.
Call and volunteer today @ 617.525.7327, or email vaccines@partners.org.
For additional information please visit www.hvtn.org
IRB number: 2002 p 000343
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1701
18. Study to Understand the Genetics of the Acute Response to Metformin and
Glipizide in Humans (SUGAR MGH)
Do you think you might be at risk for diabetes?
Does anyone in your family have diabetes?
Are you overweight?
If you are interested in participating in a new research study.
We need your help!
The Center for Human Genetic Research at Massachusetts General Hospital seeks men
and women over the age of 18 who are not currently on diabetes medication for a
research study exploring the influence of genetic background on the response to
established type 2 diabetes treatments.
Participants will be asked to visit the hospital twice in seven days.
The total time commitment is five hours for the first visit and three hours for the second
visit.
Compensation will be provided up to $100 and a free meal.
Contact Rebecca at (617)643-5419 or email rfanelli@partners.org
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000264
19. Effects of Anorexia Nervosa on Peak Bone Mass
Anorexia nervosa can cause bone loss at an early age. We are examining the effect of
estrogen administration on bone density and bone metabolism. Eligible candidates will
stay in the Massachusetts General Hospital Clinical Research Center overnight four times
over the course of one and a half years, and will need to be seen in the outpatient unit of
the Clinical Research Center seven times. The research study will include bone density
and hormonal evaluations. Estrogen (a natural female hormone) may be administered to
girls with anorexia nervosa. Up to $1,050 compensation and parking is offered.
Eligibility Criteria:
Posted 9/17/08
We are seeking 12 to 18 year old adolescent girls with anorexia nervosa and 12 to 18 year
old healthy adolescent girls.
Please contact Jenna Stark at 617 726 8201 or jnstark@partners.org for more information
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1691
20. Exploratory Analysis of Stress Reduction
Have you ever considered implementing a daily stress reduction technique into your life
to relieve your stress?
If so, we may be able to help:
Researchers at Massachusetts General Hospital are conducting a study on the
effectiveness of a stress reduction program. Study participants will receive a FREE eight
week stress reduction course to be held at MGH (a $800 value). Classes are held one
evening a week on Tuesdays for 1.5 hours at MGH. The study does not require the use of
any medications. Study participants are required to attend 2 laboratory sessions and
regularly practice learned stress reduction exercises.
Compensation will be up to $100 for completing all testing.
For more information or to enroll in the study, please call 1-866-449-6779 or email the
address below.
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000261
21. Neurobiology of Depression in Women: fMRI, Psychophysiological, and
Hormonal Aspects
Caucasian women ages 30-44 with a history of depression who are no longer depressed
are needed for a research study on hormone and brain activity in depression. This
research study involves two 4 1/2 hour visits, two weeks apart, to our imaging center at
Brigham and Women's Hospital. Both visits will include an MRI scan, blood draws, and
some questionnaires and cognitive (thinking processes) testing. You will receive up to
$250 compensation for your participation in the two visits.
If you would like to learn more about the research study, please call our depression study
coordinator, Dr. Laura Holsen, at 617-525-8772.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1591
22. Dietary Salt Intake and Vascular Function
Can Salt Affect the Blood Vessels?
The Endocrinology, Diabetes, and Hypertension Division of Brigham and Women's
Hospital seeks healthy men 18-45 years old to take part in a research study. The purpose
Posted 9/17/08
of the research study is to test whether the amount of sodium in the diet has an effect on
the function of blood vessels. This research study involves a few overnight stays in the
hospital, blood sampling, meals, and blood vessel testing. The research study will last
about 3 weeks. Compensation up to $500.
Principal Investigator: Rhonda Bentley-Lewis, MD, MBA, MMSc
If you are interested, please call Ffyona at 617-278-0672 or e-mail at
fpatel1@partners.org.
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000228
23. MEG Investigation of Brain Activity During Speech Processing
Are you 60 or older? A native speaker of English? Right-handed?
We need your help!
We are seeking research participants for a non-invasive study of brain
activity
during language tasks
Compensation $15 per hour
Participation takes ~3 hours
Email zipse@mit.edu or call 617-306-4791
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000203
24. A Psychological Study of Fear Conditioning and Extinction in Schizophrenia
We are looking for healthy volunteers, 18-65 years old, to participate in a research study
of emotional learning and memory at the Massachusetts General Hospital, East Campus,
in the Charlestown Navy Yard. You will be paid $100 for your participation. There are
two sessions on two consecutive days. The session on day 1 lasts 2-3 hours, and the
session on day 2 of the study lasts about 2 hours. During both sessions, you will undergo
an emotional learning procedure involving the application of a mild, non-painful, halfsecond electric current to the fingers. You will also fill out a few short questionnaires.
Eligibility criteria: 18-65 years old, male or female, without a history of a neurologic,
psychiatric, or substance abuse disorder.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1408
25. Breathing Device for Hypertension
Posted 9/17/08
Brigham and Women's Hospital in Boston seeks 20 to 75 year old healthy males and
females with high blood pressure (at least 135/85) to participate in a research study
investigating a new treatment for high blood pressure. You may be asked to use a
breathing device at home every day OR listen to music at home for 8 weeks. You may
continue to take your blood pressure medicines during the study. You will have your
blood pressure measured for 24 hours every 4 weeks. You will receive $250.00 payment
for participation. For more information on the "Hy-PAP study" please call (617) 877476-6732x2 or e-mail at hypap@partners.org.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1364
Disease-Specific Studies
26. Improve Depression Screening among Ethnically Diverse Older Adults with
Cardiovascular Disease
Do you have high blood pressure? Do you suffer from heart problems?
We are looking for a diverse, English-speaking population of adults aged 65 or older who
suffer from one or more cardiovascular diseases or risk factors. The purpose of this study
is to develop questions that can identify early signs of depression in older adults more
effectively than current models. Participants will be asked to answer questions relating to
mood, view of life, alcohol-use, heart problems, cultural background, and physical
changes in an interview and through questionnaires. The study will take one visit for 3090 minutes.
Compensation is $25 for participating and $25 for related transportation costs.
For more information, please contact Eileen Crehan at 508 446-7248 or Frances Yang,
Ph. D. at 617-525-6125. IRB # 2007-P-002554; BWH
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1754
27. Reduced Phosphate Intake in "Normo-Phosphatemic" Chronic Kidney Disease
Patients
We would like to study the role of phosphorous metabolism in the development of certain
hormonal problems in people with Chronic Kidney Disease. More specifically, the goals
of the research are (1) to understand the cause of hyperparathyroidism - a hormone
problem that often develops in patients who have kidney disease and (2) to test whether
decreasing phosphorus intake could help improve or prevent hyperparathyroidism.
Eligible subjects will be people with reduced kidney function who are 18 years of age or
older. Subjects will have nine visits over approximately one month. For two weeks
during this time, subjects will consume a controlled phosphorus diet provided by the
clinical research center. Some subjects will be prescribed a phosphorus binding tablet to
limit the absorption of phosphorus in the gut. Subjects will be compensated for
completing the protocol.
Posted 9/17/08
Please contact Mike at (617) 724-3416 for more information.
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000305
28. Clinical Management of Neuropathic Pain with Ramelteon
Do you have nerve pain?
If so, we welcome you to participate in our research study at the Massachusetts General
Hospital Center for Translational Pain Research. We are evaluating the effectiveness of a
FDA-approved sleep medication on nerve pain. If you are 18-65 years old and have been
diagnosed with a nerve pain condition for at least 3 months you may be eligible to
participate.
The study consists of:
four study visits;
two phone interviews;
keeping sleep and pain diaries;
completing questionnaires;
a urine test;
a brief office physical exam
taking study medication.
Compensation will be provided.
For further information, please contact:
Charlene Malarick, RN, BSN at
617 724-6102 or toll-free at 1-888-No-2-Ouch
cmalarick@partners.org
www.massgeneral.org/painresearch
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1752
29. Safety and therapeutic efficacy of cerebellar repetitive transcranial magnetic
stimulation in patients with schizophrenia
SEEKING PATIENTS WITH SCHIZOPHRENIA
Study using a new technique of noninvasive brain stimulation is recruiting participants
with schizophrenia.
- If you are between 18 and 65 years old and have not fully responded to medications
- Have no prior neurosurgical procedures, previous head injury or history of seizure
- And do not have an implanted pacemaker or any metallic hardware in the head
Posted 9/17/08
You might be eligible to participate in an inpatient study investigating the effects of a
new non-invasive technique of brain stimulation on cognitive functions.
Up to $200 compensation will be provided.
For more information, please contact Dr. Asli Demirtas Tatlidede at 617- 667- 0383 or
ademirta@bidmc.harvard.edu
IRB Protocol #: 2007-P-000395/2; BIDMC
[This is a collaborative study between the MGH Ataxia Unit / Cognitive Behavioral
Neurology Unit, and the BIDMC Behavioral Neurology Unit.]
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1751
30. Do you have HIDRADENITIS SUPPURATIVA (Boil-like lesions, abscesses and
scars on the armpits and groin)?
You may qualify for a research study of an investigational oral medication
Females - 14-45 years of age
9 study visits over 6 months
Compensation up to $360 for time and travel
For more information, please e-mail harvardskinstudies@partners.org
or call (617) 726-5066
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000304
31. Memory Reconsolidation Blockade as a Novel Intervention for Nicotine
Dependence
Have you quit in the past but resumed smoking?
Have you been smoking 10 or more cigarettes a day for the past 6 months?
Are you between the ages of 18 and 65?
We are conducting a 12-week smoking cessation and relapse prevention research study.
The purpose of this study is to find out whether a medication called propranolol can help
to prevent people from having a smoking relapse by reducing cravings to smoke.
The study involves a smoking cessation phase, where you will be given nicotine patches
at no cost to help you quit smoking, and a relapse prevention phase where you will be
assigned to receive either propranolol or placebo (contains no active medication) once a
week for 6 weeks.
Posted 9/17/08
Study participation involves weekly visits to our clinic at Massachusetts General
Hospital. You may be eligible to participate in the study at no cost to you. Compensation
up to $300 and free parking will be provided.
If interested, please call 617-643-4691 or email Dr Pachas at gpachas1@partners.org.
All inquiries are completely confidential.
IRB #2007-P-001903
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1747
32. A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multicenter
Study to Evaluate the Efficacy and Safety of Ad5FGF-4 in Female Patients With
Stable Angina Pectoris Who are Not Candidates for Revascularization.
Researchers at Massachusetts General Hospital in Boston, MA are currently enrolling
women who suffer from chest pain due to heart disease. If you have had a prior bypass
graft or stent procedure but still have chest pain, and can take an exercise treadmill test,
you may be eligible to enroll in this research study. The study includes 2-3 screening
visits, 6 study visits, and yearly phone follow-up for four years. The study will reimburse
out-of-pocket expenses. If you are interested in participating or would like more
information please contact Voula Christopoulos, the research coordinator, at 617-6432890 or by e-mail at vchristopoulos1@partners.org
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1744
33. Reducing High Risk Behaviors Among Bipolar Patients Transitioning to
Adulthood
Do you have frequent mood swings? Do you go through times when you feel "too good,"
overly excited or confident, overly active, or unusually irritable? Have you ever been
diagnosed with mania or bipolar disorder? Are you between the ages of 18 and 24 years?
If so, we would welcome your participation in our study of cognitive behavioral therapy
(CBT) for bipolar disorder in young adults. This study uses CBT strategies for:
1) Learning to manage symptoms of bipolar disorder
2) Improving problem-solving and daily functioning skills
3) Enhancing health-promoting behaviors
The intervention consists of 14 60-minute individuals sessions.
The intervention is provided is at no cost.
For more information, please contact Caroline at 617-503-1411.
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000301
34. Behavioral modifications and Lorcaserin for Overweight and Obesity
Management in Diabetes Mellitus A 52-Week, Double-blind, Placebo-controlled,
Posted 9/17/08
Parallel-group Study to Assess the Safety and Efficacy of Lorcaserin Hydrochloride
in Overweight and Obese Patients with Type 2 Diabetes Mellitus Managed with
Oral Hypoglycemic Agent(s)
The MGH Weight Center is now enrolling for a new clinical trial for the treatment of
diabetes and obesity!
You may be eligible to take part in a clinical research study with an experimental drug for
the treatment of diabetes and obesity. This medication has shown to help short-term (12week) weight loss in previous studies and will be tested to determine effectiveness for
long-term weight loss.
The study will run for 64 weeks. Study related exams and drug as well as periodic
nutritional counseling will be provided free of charge for those who qualify.
Remuneration of up to $700 will also be provided.
The study will consist of:
. taking a study drug or placebo (sugar pill - no active medicine or drug ) for 1 year
If you take part in this study, you may not get the study drug
. individual nutritional counseling
. monthly visits to the MGH Weight Center to meet with the study team and dietitian
Eligible subjects must:
. be between the ages of 18 and 65
. have Type-II diabetes
. be overweight
. willing and able to commit to the study and taking the medication (or placebo) for 1
year
Institution - Massachusetts General Hospital, Boston, MA
Principal Investigator - Lee M. Kaplan, MD, PhD
Enrollment Information
For further information about enrolling a patient in this trial, contact the person below.
Name - Anna Moseman, Study Coordinator
Email - amoseman@partners.org
Phone - 617-724-9616
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000296
35. Brain Function, Structure and Genes in Obsessive Compulsive Disorder
Children Ages 10-17 Wanted for a Study of Brain Function, Structure and Genes in
Obsessive Compulsive Disorder (OCD)
Posted 9/17/08
Is there a 10-17 year old child in your family who suffers from unwanted thoughts,
worries and behaviors that they can't stop or who has been diagnosed with obsessive
compulsive disorder (OCD)?
If so, this child could participate in a research study at the Massachusetts General
Hospital (MGH) and McLean Hospital.
The purpose of this study is to learn more about OCD. We are interested in learning more
about how the brain functions and how certain genes affect the brain in people with OCD
compared to people who do not have OCD.
Participants will be interviewed by a study doctor and will undergo structural and
functional magnetic resonance imaging (MRI) to take pictures of their brains. We will
also collect a saliva sample from participants to look at their genes.
This study will require two study visits, each lasting approximately 1.5-2 hours.
Participants must be right-handed.
Children will receive up to $125 in gift certificates for their participation.
Note: MRI uses strong magnets and people with metal in their body may not be able to
participate.
For more information on how to participate, please call the study coordinator at (617)
855-2239 or email lmanning@mclean.harvard.edu.
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000293
36. Omega 3-Fatty Acids for Treatment of Major Depression: Differential Effects of
EPA and DHA, and Associated Biochemical and Immune Parameters
Omega-3 EPA vs. DHA Fatty-Acid Depression Study
Do you feel sad, blue, or down in the dumps?
Do you no longer enjoy the things you used to?
Do you have trouble falling asleep, staying asleep?
Do you feel tired all the time, even after a good night's sleep?
These might be the symptoms of what researchers refer to as major depression. It is
believed that a deficiency of Omega-3 fatty acids can lead to the development of major
depression. Omega-3 fatty acids such as EPA and DHA are commonly found in fish oils,
for instance Salmon, Mackerel, and Tuna. If untreated, depression can affect a person's
daily functioning and quality of life. If you are at least 18 years old and have symptoms
of depression, you may be eligible to participate at no cost in a Massachusetts General
Posted 9/17/08
Hospital research study that evaluates the two natural supplements, EPA and DHA
Omega-3 fatty acid, as a treatment for depression.
For more information about this and other studies, please contact 1-877-55-BLUES or
email Soo at syoun@partners.org.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1739
37. A Double-Blind, Placebo Controlled Study of Maca Root for the Treatment of
Sexual Dysfunction Associated with the Treatment Regimen for Bipolar Disorder in
Females
Are you taking medication for bipolar disorder and experiencing sexual side effects?
If you are a female, aged 18-80 and experiencing sexual dysfunction due to psychotropic
medications for bipolar disorder, you may be eligible to participate at no cost to you in a
12-week research study of a natural compound called Maca Root. Maca Root has been
used for centuries in South America for nutritional and medicinal purposes. This study is
designed to determine whether Maca Root is effective in the treatment of sexual
dysfunction associated with the treatment regimen for bipolar disorder.
If interested, please call Lara Sinicropi-Yao @ 617-726-3129 or LSinicropiYao@partners.org. All inquiries will be completely confidential.
This study is being conducted by the Depression Clinical and Research Program at The
Massachusetts General Hospital.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1737
38. A Double-Blind, Placebo Controlled Study of Maca Root for the Treatment of
Antidepressant Induced Sexual Dysfunction in Females
Are you taking antidepressants and experiencing sexual side effects?
If you are a female, aged 18-80 and experiencing sexual dysfunction due to
antidepressant medication, you may be eligible to participate at no cost to you in a 12week research study of a natural compound called Maca Root. Maca Root has been used
for centuries in South America for nutritional and medicinal purposes. This study is
designed to determine whether Maca Root is effective in the treatment of antidepressant
induced sexual dysfunction.
If interested, please call ]Lara Sinicropi-Yao @ 617-726-3129 or LSinicropiYao@partners.org. All inquiries will be completely confidential.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1736
39. Does Memantine Improve Verbal Memory Task Performance in Subjects with
Left Temporal Lobe Epilepsy and Memory Dysfunction? A Randomized, DoubleBlind, Placebo-Controlled Trial.
Posted 9/17/08
Does memantine improve verbal memory task performance in patients with left temporal
lobe epilepsy and memory dysfunction? A randomized, double-blind, placebo-controlled
trial.
Many patients with epilepsy have memory deficits. Unfortunately, the treatment options
for memory dysfunction in patients with epilepsy are limited. We are conducting a study
to evaluate the effects of memantine, a medication used for the treatment of Alzheimer's
Disease, for the treatment of verbal memory dysfunction in subjects with left temporal
lobe seizures. The study involves randomization to memantine therapy or placebo, with
cognitive testing and EEG pre- and post-treatment.
All subjects must:
. Be 18-55 years of age
. Have left temporal lobe seizures
. Be native English-speaking
. Be able to give consent
. Have self-reported memory dysfunction
Participation will require two study visits over the 13-week duration of the trial. Each
subject will be offered $100 dollars for participation, parking and meal vouchers, as well
as free study medication during the trial.
If you or your doctor feel that you might be a candidate for this study, or if you wish to
obtain more information, please contact:
Beth Leeman, M.D.
Phone: 617-726-3311
E-mail: baleeman@partners.org
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000292
40. Cognitive Effects of Treatment of Interictal Discharges
Cognitive effects of treatment of interictal discharges
Many patients with epilepsy have subtle or transient cognitive deficits in the setting of
otherwise normal intelligence. It is thought that frequent interictal discharges may
contribute to this phenomenon. It is unknown, however, whether treatment of the
discharges will improve cognitive performance. We are conducting a study to evaluate
the effects of treatment of focal or generalized interictal discharges with levetiracetam or
lamotrigine, respectively. We will be assessing whether these drugs do in fact reduce
abnormal interictal activity, and whether this reduction correlates with improved
cognitive task performance. The study involves patients diagnosed with seizures, who
will be placed on levetiracetam monotherapy for focal seizure prevention or lamotrigine
monotherapy for generalized seizure prevention. The study will include subjects with and
without frequent interictal epileptiform discharges. Subjects will undergo repeated EEG
Posted 9/17/08
and cognitive testing pre- and post-treatment. The trial duration is 11 weeks for those
taking levetiractam, and 15 weeks for those taking lamotrigine.
Subjects with epilepsy must meet criteria which include:
● 18-55 years of age
● The subject's treating physician is planning to prescribe levetiracetam for focal
seizure or lamotrigine for generalized seizure prevention
● Untreated with antiepileptic medications at the time of enrollment
We are also recruiting healthy adult control subjects, aged 18-55 years, to undergo EEG
and cognitive testing without taking medication. Healthy controls will participate in three
testing sessions over 15 weeks.
If you or your doctor feel that you might be a candidate for this study, or if you wish to
obtain more information, please contact:
Beth Leeman, M.D.
Phone: 617-726-3311
E-mail: baleeman@partners.org
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000291
41. Cognitive-Behavior Therapy for Depression in Bipolar Disorder
The MGH Bipolar Clinic and Research Program is currently seeking volunteers to
participate in a research study evaluating a psychosocial therapy for the treatment of
depressive symptoms in patients with bipolar disorder. In this study, patients will receive
18 sessions of therapy for bipolar depression and a brain scan at no cost.
Bipolar patients above the age of 18, who are currently in a depressive episode, please
contact Rebecca Ametrano at rametrano@partners.org or call (617)-724-6545 for more
information. IRB#2006P001521
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000289
42. A three-phase study designed to test the efficacy, tolerability and safety of the
combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI)
Escitalopram for patients with Major Depressive Disorder (MDD) that do not
sufficiently respond to treatment with Escitalopram
The current research study is looking for participants between the ages of 18-65, who are
depressed and are not currently taking any medication. If eligible, participants will
receive the FDA approved antidepressant medication Escitalopram (Lexapro) for at least
10 weeks. At the end of 10 weeks, subjects who have improved on the medication will be
offered 3 months of follow up care at no cost. For those subjects who have NOT
improved on the medication, they may be eligible to continue on Lexapro and receive, in
addition, either Ziprasidone or placebo. Placebo is sometimes called a sugar pill, and it
Posted 9/17/08
looks like a study drug but it doesn't contain any active medication. At the end of the
study, all participants will be offered 3 months of follow up care at no cost.
For more information about this and other depression studies, please call 1-877-55BLUES or contact Soo directly at 617-724-2936 or syoun@partners.org
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000288
43. Laboratory Evaluation of Neuropathic Pain
Are you healthy and 70 years or older?
We seek men and women to participate as healthy controls (comparison group) for a
diabetes research study. You must have never had diabetes. This study involves a single
visit to the Mass General hospital during which you will have a glucose tolerance test to
screen for diabetes. Recent normal results of this test can be used instead. You will also
have two small punch skin biopsies removed from your lower leg under local anesthesia.
Payment for participation is offered. For more information, please contact Heather
Downs of the MGH Neurology Department at 617-726-0260 (HDowns@partners.org).
IRB#99-9042
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=333
44. Do you have ASTHMA?
You may be able to participate in a research study.
You MUST be taking an inhaled steroid AND :
- Be 18 - 55 years old
- Have allergic asthma
- Be a lifelong non-smoker
- If female, be post-menopausal or surgically sterile
This study is looking at a new medication for asthma. All study medications and visits are
provided at no cost. Compensation provided.
For more information please contact:
617-726-6376 or mstier@partners.org
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1729
45. A Double-Blind, Placebo-Controlled Trial of the NMDA Glycine Site
Antagonist, GW468816 for Prevention of Relapse to Smoking
Smoking Cessation and Relapse Prevention Research Study
Do you want to quit smoking once and for all?
Posted 9/17/08
Have you been smoking 10 or more cigarettes a day for the past 6 months?
If you are a female between the ages of 18 and 65, you may be eligible to participate in
our research study at no cost to you. The study involves an 8-week smoking cessation
phase, where you will be given free nicotine patches to help you quit smoking. If you are
able to successfully quit smoking after 7 weeks of nicotine replacement therapy (i.e. the
patch), you will enter into the 5-week relapse prevention phase of the study where you
will stop using the patch, and you will be randomly assigned to receive an investigational
drug that may be an effective treatment in helping prevent recently quit smokers from
relapsing or placebo (i.e. inactive medication).
Study participation involves weekly or biweekly visits to our clinic at Massachusetts
General Hospital and the completion of computerized and behavioral tasks at three points
throughout the 15-week study. Additional compensation will be provided.
If interested, please call 617-724-8472 or email quitforgood@partners.org. All inquiries
are completely confidential.
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000272
46. Comparison of LANTUS and NPH in The DAWN PHENOMENON
Subject: Comparison of Lantus and NPH Insulin in the Dawn Phenomenon
Massachusetts General Hospital, Diabetes Research Center, seeks individuals with Type
1 diabetes for a research study to better understand how two different types of long-acting
insulin affect blood sugar control during the early morning hours. Study involves: 1.
Three daytime outpatient visits at the Diabetes Research Center, including nutritional
counseling, teaching of the Continuous Glucose Monitoring System(CGMS). 2. Two
overnight inpatient hospital stays during which blood samples will be obtained through
an intravenous (in the vein) line. Study requirements: Candidates must have Type 1
diabetes for 5 or more years, be between the ages of 18-60, and must use either glargine
(lantus) or NPH insulin. Compensation: Up to $220. All tests and alternate insulins
provided at no cost. For more info :Christine Stevens RN, study coordinator at 617-6430915. IRB#2005-p-002515
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1713
47. Determination of Dosing and Frequency of BCG Administration to Alter TLymphocyte Profiles in Type I Diabetics
People with Type 1 diabetes have abnormal white blood cells in their body. These
abnormal cells - also called "autoreactive cells" - help destroy the cells in the pancreas
that make insulin. When this happens, people develop Type 1 diabetes.
In this study, we will use a vaccine called BCG, which is commonly used to protect
people against tuberculosis, to try to reduce the number of abnormal autoreactive cells.
Researchers have used this vaccine in mice with Type 1 diabetes and it reduced the
Posted 9/17/08
number of autoreactive cells and helped cure their diabetes. Now we want to find out if
BCG can reduce the number of these abnormal cells in people with type 1 diabetes.
The study is being conducted at the Diabetes Research Center of Massachusetts General
Hospital.
You may be eligible if you:
Have used insulin continuously since being diagnosed with diabetes
Are aged 18-55
Have an A1C of 8.0 or less
Can come to morning visits starting between 8:00am to 9:30am.
The study involves 17 visits over a 6 month period.
Travel and parking expenses will be reimbursed.
To see if you qualify for the study, or for more information, please contact:
Richard Pompei, RN at rpompei@partners.org or 617-726-2141
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1712
48. Closed Loop Glucose Control for Automated Management of Type 1 Diabetes
Do you have type 1 diabetes and use an insulin pump? Volunteers wanted for a study of
an automated, closed-loop blood glucose control device.
The MGH Diabetes Center is performing a research study on a device for automated,
closed-loop blood glucose control (sometimes called an "artificial pancreas") in people
with type 1 diabetes. You may be eligible for this study if you are more than 18 years old,
have type 1 diabetes diagnosed at least 5 years ago, use an insulin pump, and have a
hemoglobin A1c of 8.5% or less.
There will be four study visits. The first visit will determine whether you meet all of the
requirements for participation. This visit will take about two hours and involves a
physical exam, a mixed-meal tolerance test, timed blood tests, and an EKG. If you
qualify, we will schedule two 29-hour overnight stays in the General Clinical Research
Center at MGH. Both of these admissions involve insertion of two IV catheters for
frequent blood sampling. During one of the visits you will use your own insulin pump to
control your blood sugar. During the other, your own insulin pump will be removed,
three new infusion sets will be placed, and the closed-loop device will control your blood
sugar by infusion of insulin and glucagon. Two days before the closed-loop visit, there
will be a brief visit to place a small sensor in the skin for continuous glucose monitoring
by the Abbott Navigator. You will need to check your blood sugar three times over the
next two days using the Navigator's built-in meter. During the closed-loop visit you will
also wear two other continuous glucose monitors, the MiniMed Guardian RT and the
Posted 9/17/08
Dexcom Seven System. Compensation will be $750 for completion of all four visits. You
may be offered the option to do one more closed-loop visit, in which case the
compensation will be $1050.
For additional information, please contact the study coordinator, Robert Sutherlin, R.N. at
617-724-6237 or email rsutherlin@partners.org. IRB Protocol: 2007p-000101
Version 1, 05-01-08
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1709
49. Bipolar Disorder in Pregnancy and the Postpartum Period: Predictors of
Morbidity
Bipolar Disorder In Pregnancy
Are you an expectant mother? Do you have questions about bipolar disorder and
antidepressants or mood-stabilizers during pregnancy? The Center for Women's Mental
Health at Massachusetts General Hospital is conducting a research study on Bipolar
Disorder in pregnancy. If you are pregnant and diagnosed with bipolar disorder (or manic
depression) you may be eligible for this research study. Participants meet with research
coordinators and psychiatrists who specialize in bipolar illness during pregnancy. For
more information contact Rachel at (617) 726-2912.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1707
50. COCOA, POLYPHENOLS, AND THE KIDNEY IN HEALTHY SUBJECTS
AND IN SUBJECTS WITH HYPERTENSION AND DIABETES MELLITUS
Healthy subjects and subjects with diabetes mellitus, 18 to 85 years old, are needed for a
14-day research study including two inpatient admissions (over the course of 2 separate
admissions) to the General Clinical Research Center at Brigham and Women's Hospital.
Subjects will be kept on a constant diet, while drinking 2 cups of cocoa each day. We are
studying blood vessel response to cocoa.
Eligibility criteria:
· Male or female, ages 18-85
· Diagnosed with Type I or II Diabetes Mellitus
· No heart attack or stroke in the last six months
$300 compensation upon completion of the study
For more information, please contact Heather or Tina at (617)732-6901 or e-mail
hhassett@partners.org or esampong@partners.org
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1703
51. Treatment of Preclinical Hypertrophic Cardiomyopathy with Diltiazem
Researchers at Brigham and Women's Hospital in Boston, MA are currently enrolling
participants for a research study of Hypertrophic Cardiomyopathy (HCM). HCM is an
Posted 9/17/08
inherited heart disorder affecting 1 in 1000 individuals. People with HCM have
unexplained thickening of the heart wall called left ventricular hypertrophy (LVH). HCM
is caused by mutations in genes involved in the heart's ability to contract and relax. You
qualify for this research study if you are known to carry a gene mutation that puts you at
risk for developing HCM but do not currently have any clinical signs of HCM. The study
is interested in learning whether a medication called diltiazem can be used to treat and
prevent the progression of HCM. Diltiazem is FDA approved to treat hypertension but its
use for HCM is experimental. The study will last for five years and includes taking a pill
(Diltiazem or inactive sugar pill) once a day for the first four years. Participants will be
asked to come to the hospital for up to 12 study visits in five years (four years while
taking the study drug and one year after for follow-up).
To learn more about the study, please contact Allison L. Cirino, MS, CGC at 617-7327921 or acirino@partners.org.
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1698
52. Renin Inhibition and the Kidney
42 subjects with Type II Diabetes Mellitus, 18-75 years old, are needed for a 14-day
research study including 3 inpatient days (over the course of 2 separate admissions), to
the General Clinical Research Center at Brigham and Women's Hospital. Subjects will
receive intravenous (in the vein) infusions on 3 different mornings in order to study the
kidney's response to the renin inhibitor, aliskiren (a drug, which blocks renin, a protein
made by the kidney). There is a possibility that aliskiren may be useful in preventing
injury to the kidneys of people with Hypertension and Diabetes. $1,000 compensation
upon completion of the study.
Eligibility criteria:
· Male or female, ages 18-75
· Diagnosed with Type II Diabetes Mellitus AND Hypertension (high blood pressure)
· No heart attack or stroke in last six months
· No history of ECG abnormalities
· No history of gastrointestinal issues
· Women must be either post-menopausal or surgically sterilized
For more information, please contact Heather or Tina at (617)732-6901 or e-mail
hhassett@partners.org or esampong@partners.org
More information can be found at : http://clinicaltrials.partners.org/trials.aspx?tId=1694
53. A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging
Study to Assess the Efficacy and Safety of TZP-101 when Administered as a 30
Minute I.V. Infusion to Subjects with Severe Gastroparesis due to Diabetes Mellitus
(TZP-101-CL-G004)
Do You Have Type 1 or Type 2 Diabetes and have been diagnosed with Gastroparesis?
Posted 9/17/08
Massachusetts General Hospital is seeking volunteers to participate in a Clinical
Research Study using an investigational medication.
To qualify you must be:
. 18-80 years of age
. Diagnosed with Type 1 or Type 2 Diabetes Mellitus
. Diagnosed with gastroparesis
. Male or Female must be willing to use contraceptives (birth control) to prevent
pregnancy
. Able and willing to participate up to 35 days from screening through follow-up,
including 5 consecutive overnight stays
Do you have any of the following conditions:
. vomiting of undigested food-sometimes several hours after a meal
. early feeling of fullness after only a few bites of food
. abdominal bloating
. nausea
. pain in the upper abdomen
Qualified participants will receive research study related:
. Lab Assessments
. EKG's
. Investigational Medication
Monetary compensation is available for eligible subjects.
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000266
54. Mitral Valve Prolapse genetic study
The Center for Human Genetic Research and the Cardiac Ultrasound Lab at MGH are
looking for subjects and or their family members with Mitral Valve Prolapse. Subjects
will be enrolled into a genetic study that will involve an echo-diagnosis of MVP and a
one time blood draw of approximately 8 teaspoons. All participants that come to MGH
will be reimbursed for parking. Time commitment will be no longer than 1 hour. If you
are interested please contact Leah Rastiello at 617-821-0495 or by email:
lrastiello@chgr.mgh.harvard.edu
More information can be found at :
http://clinicaltrials.partners.org/trials.aspx?tId=100000263
Posted 9/17/08