1
CURRICULUM VITAE 2010
NAME: MICHAEL DAVIS
BORN: November 14, 1942 Bronxville, New York.
EDUCATION:
B.A., Northwestern University, Evanston, Illinois, 1965
Ph.D., Yale University, New Haven, Conn. 1969
CAREER:
1969-1970
Research Associate, Department of Psychiatry, Yale University School of
Medicine
1970-1975
Assistant Professor of Psychology in Psychiatry, Department of
Psychiatry, Yale University School of Medicine
1975-1980
Associate Professor of Psychology in Psychiatry, Department of
Psychiatry, Yale University School of Medicine
1980-1984 Associate Professor of Psychiatry and Psychology, Department of
Psychiatry, Yale University School of Medicine
1984-1998
Professor of Psychiatry and Psychology, Departments of Psychiatry and
Psychology, Yale University School of Medicine
1998-present Robert W. Woodruff Professor of Psychiatry and Behavioral Sciences,
Department of Psychiatry, Emory University School of Medicine
PROFESSIONAL HONORS:
Phi Beta Kappa, Northwestern University, 1965
Woodrow Wilson Fellow, Yale University, 1965-1966
National Science Foundation Fellow, Yale University, 1966-1969
Sterling Fellow, Yale University, 1968-1969 (Outstanding Graduate Student)
Public Health Service Research Scientist Development Award, Type I, 1975-1979
Public Health Service Research Scientist Development Award, Type II, 1980-1984
Public Health Service Research Scientist Award, Level V, 1985-1989
Public Health Service Research Scientist Award, Level V, 1990-1994
Public Health Service Research Scientist Award, Level V, 1995-1999
MERIT Award, National Institute of Mental Health, 1991-2001
MERIT Award, National Institute of Mental Health, 2002-2012
First Matthew Wayner-Noke Pharmaceuticals Award in Behavioral Neuroscience,
International Behavioral Neuroscience Society, 2005
APA Distinguished Scientific Contributions Award, American Psychological
Association, 2006
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Institute of Scientific Information: Named as one of the “Highly Cited Scientists”,
greater than 15,000 citations
The Pavlovian Research Award, Pavlovian Society, 2006.
2008 Ed Scolnick Award in Neuroscience, McGovern Institute, Massachusetts Institute
of Technology
2008 “Distinguished Friend to Behavior Therapy” Award. Association of Behavioral and
Cognitive Therapies
OTHER PROFESSIONAL ACTIVITIES:
American Psychological Association (Fellow)
American Psychological Society (Fellow)
American Association for the Advancement of Science (Fellow)
Academia, Medicinae & Psychiatriae Foundation (Fellow)
Society for Neuroscience
American College of Neuropsychopharmacology (Fellow)
Society for Psychophysiological Research
International Behavioral Neuroscience Society
Editorial Board - Journal of Experimental Psychology, 1975-1977
Editorial Board - Behavioral Neuroscience, 1991-present
Editorial Board - Behavioral and Neural Biology, 1992-present
Editorial Board - Psychonomic Bulletin and Review, 1993-present
Editorial Board - Learning and Memory, 1993-present
Editorial Board – Anxiety and Depression, 1993-2008
Editorial Board - Journal of Neuroscience, 1995-present
Editorial Board - Biological Psychology, 1998-present
Editorial Board - Neuropsychopharmacology, 2002-present
Member: Basic Psychopharmacology Initial Review Group, NIMH, 1982-1986
Human Capital Initiative Steering Committee, American Psychological Society, 19911993
Society of Neuroscience Representative to National Science Foundation regarding
formation of a new Behavioral Sciences Directorate - 1991
Principle Organizer of 1993 Meeting on Learning and Memory - Park City, Utah, 19921993
Consultant to National Institute of Mental Health on prospective joint venture with
NASA on the 1998 Neurolab Shuttle Mission, 1992
Consultant to National Institute of Mental Health on future of behavioral research at
NIMH, 1992
Traveling speaker for CURE (Connecticut United for Research Excellence), 1992 - 1998
Society for Neuroscience Committee on Animals in Research, 1995-1998
Organizing and Program Committee Member for Gordon Conferences on Neural
Plasticity 1992 - 1999
Scientific Advisory Board- Neurogen Corporation 1988-1998
Scientific Advisory Board- Helicon Corporation 1999-present
Vice President for Research – SyneurRx Corporation 2005-present
Program Committee - American College of Neuropsychopharmacology - 1996-1999
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Member: Initial Review Group on "Phenotyping the mouse nervous system and
behavior" 1999
Nominating Committee - American College of Neuropsychopharmacology – 2001
American Association for the Advancement of Science: Member at large – 2002Advisory Board, Anxiety Disorders Association of America– 2002-present
Member: American College of Neuropsychopharmacology Credentials Committee –
2003-2005
Member: NIMH Committee for Setting Priorities for Scientific Research – 2004
Council Member: American College of Neuropsychopharmacology – 2004-2007
Invited Guest Editor: Learning and Memory: Volume on Extinction Nov, 2004
Council Liason: Publications Committee, American College of
Neuropsychopharmacology – 2004-2007
Council Liason: Awards Committee, American College of Neuropsychopharmacology –
2004-2007
Member: Institute of Medicine Committee on Gulf War and Health: Physiologic,
Psychologic, and Psychosocial Effects of Deployment Related Stress, 2005-2008.
Member: Search committee for the Division of Neuroscience & Basic Behavioral
Science of the NIMH, 2006
Member: Grand Challenges of Mind and Brain, National Science Foundation panel to set
research priorities for NSF for the next 10 years, 2006
Support 2010
Active
R37 MH47840 (Davis, PI)
07/01/02 – 06/30/12
NIMH (MERIT Award)
$250,000
Anatomy and Pharmacology of Fear-Potentiated Startle.
This grant looks at the role of the amygdala in rodent models of fear and anxiety.
P50 MH072850 U of Florida (Lang, Davis, CoPI)
09/01/05 - 06/30/10
NIMH
$157,077 (Davis part)
Role of Medial Nucleus of the Amygdala in Fear Inhibition
This grant looks at the role of the medial nucleus of the amygdala in conditioned
fear.
R01 MH070880 (Rothbaum, Davis, CoPI)
09/30/05 - 08/31/11
NIMH
$12,669 (Davis part)
A Cognitive Enhancer May Facilitate Behavioral Exposure Therapy
This grant is testing whether D-cycloserine will facilitate psychotherapy in
soldiers returning from Iraq
1 R34MH083078 (Rothbaum, Davis, CoPI)
07/11/08 - 06/30/11
NIMH
$12,669 (Davis part)
Effects of Early Psychological Intervention to Prevent PTSD
This grant is testing whether intensive psychotherapy in the emergency room
shortly after a traumatic event with prevent the development of PTSD
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1U19 MH069056 (Mayberg, PI, Davis, CoPI)
09/4/09 – 05/31/14
Emory, GSK-NIMH
$150,000 (Davis part)
Emory-MSSM-GSK-NIMH Collaborative Mood and Anxiety Disorders
Initiative - Rat and Mouse Models of Depression and Anxiety
The goal is to evaluate how serotonin reuptake inhibitors and GSK compounds
will affect our measures of fear vs. anxiety and whether over expression of CRF
in CRF neurons in the amygdala will provide a novel model of anxiety.
1R21MH086947 (Davis, Bachevalier, MPIs)
07/01/09 - 06/30/11
NIMH
$207,875
Safety Signal Learning in Monkeys: Cortical Regulation and its Development
The goal is to investigate whether specific orbital frontal fields are involved in
the acquisition and/or expression of conditioned safety signal learning in male
and female adult monkeys (R21 phase) and follow monkeys longitudinally to
determine when orbital frontal regulation of conditioned inhibition emerges in
primates of both sexes.
1RC1 MH088985-01 (Davis, PI, Sanchez, CoPI)
09/30/09 - 09/29/11
NIMH
$223, 275
Safety signal learning in Rhesus monkeys following early life stress (Challenge
Grant)
The goal of this grant is to determine the role of early life stress in humans and
non-human primates in learning safety.
1R01MH080330 (Walker, PI, Davis, CoPI)
04/1/10 – 03/31/15
NIMH
$225,000
Neural Substrates of Phasic vs. Sustained fear
This grant looks at the role of the central nucleus of the amygdala vs. the bed
nucleus of the stria terminalis on fear vs. anxiety
BIBLIOGRAPHY:
Original Articles
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Davis, M., Nonneman, A., and Glickman, S.E. Chemical stimulation of the
midbrain reticular system. Psychological Reports, 1967, 20, 507-509.
Davis, M. and Wagner, A.R. Startle responsiveness after habituation to different
intensities of tone. Psychonomic Science, 1968, 12, 337-338.
Davis, M. and Wagner, A.R. Habituation of the startle response under an
incremental sequence of stimulus intensities. Journal of Comparative and
Physiological Psychology, 1969, 67, 489-492.
Davis, M. Effects of interstimulus interval length and variability on startleresponse habituation in the rat. Journal of Comparative and Physiological
Psychology, 1970, 72, 177-192.
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Davis, M. Interstimulus interval and startle response habituation with a
"control" for total time during training. Psychonomic Science, 1970, 20, 39-41.
Davis, M. and Sollberger, A. Twenty-four-hour periodicity of the startle
response in rats. Psychonomic Science, 1971, 25, 37-39.
Davis, M. Differential retention of sensitization and habituation on the startle
response in rats. Journal of Comparative and Physiological Psychology, 1972,
78, 260-267.
Davis, M. and Bear, H.D. Effects of N-N-Dimethyltryptamine on retention of
startle response habituation in the rat. Psychopharmacologia, 1972, 27, 24-44.
Davis, M. and Heninger, G.R. Comparison of response plasticity between the
eyeblink and vertex potential in humans. Electroencephalography and Clinical
Neurophysiology, 1972, 33, 283-293.
Davis, M. and Zolovick, A.J. Habituation of the startle response in
adrenalectomized rats. Physiology and Behavior, 1972, 8, 579-584.
Sollberger, A. and Davis, M. Diural rhythm of the startle response: A statistical
analysis. Journal of Interdisciplinary Cycle Research, 1972, 3, 313-325.
Davis, M. and Sheard, M.H. Habituation and sensitization of the rat startle
response: Effects of raphe lesions. Physiology and Behavior, 1974, 12, 425-431.
Davis, M. Signal-to-noise ratio as a predictor of startle amplitude and
habituation. Journal of Comparative and Physiological Psychology, 1974, 86,
812-825.
Davis, M. and Sheard, M.H. Effects of lysergic acid diethylamide (LSD) on
habituation and sensitization of the startle in rats. Pharmacology, Biochemistry,
and Behavior, 1974, 2, 675-683.
Davis, M. Sensitization of the startle response by noise. Journal of Comparative
and Physiological Psychology, 1974, 87, 571-581.
Davis, M. and Sheard, M.H. Biphasic dose-response effects of N,Ndimethyltryptamine on the rat startle reflex. Pharmacology, Biochemistry and
Behavior, 1974, 2, 827-829.
Aghajanian, G.K. and Davis, M. A new method of direct chemical brain
stimulation using microiontophoresis. Pharmacology, Biochemistry, and
Behavior, 1975, 3, 127-131.
Davis, M., Svensson, T., and Aghajanian, G.K. The effects of d- vs lamphetamine on habituation and sensitization of the startle response.
Psychopharmacologia, 1975, 43, 1-11.
Sheard, M.H., Astrachan, D.I., and Davis, M. Effect of noise on shock-elicited
fighting in rats. Nature, 1975, 257, 43-44.
Sorenson, C.A. and Davis, M. Effects of 6-hydroxydopamine and alphamethylparatyrosine on the acoustic startle response in rats. Pharmacology,
Biochemistry and Behavior, 1975, 3, 325-329.
Davis, M. and Sheard, M.H. Parachloroamphetamine (PCA): Acute and chronic
effects on habituation and sensitization of the startle response in rats. European
Journal of Pharmacology, 1976, 35, 261-273.
Davis, M. and D'Aquila, R. Acute intravenous infusion in freely moving rats
through the sagittal and transverse sinuses. Pharmacology, Biochemistry, and
Behavior, 1976, 4, 469-472.
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23. Davis, M. and Aghajanian, G.K. Effects of apomorphine and haloperidol on the
acoustic startle response in rats. Psychopharmacology, 1976, 47, 217-233.
24. Weiss, G.T. and Davis, M. An automated system for acquisition and reduction
of startle data. Pharmacology, Biochemistry and Behavior, 1976, 4, 713-720.
25. Sheard, M.H. and Davis, M. Shock-elicited fighting in rats: Importance of
intershock interval in the effects of parachlorophenylalanine. Brain Research,
1976, 111, 433-437.
26. Davis, M. and Gendelman, P.M. Plasticity of the acoustic startle reflex in
acutely decerebrate rats. Journal of Comparative and Physiological Psychology,
1977, 91, 549-563.
27. Sheard, M.H. and Davis, M. p-Chloroamphetamine: Acute and chronic effects
on shock-elicited aggression in rats. European Journal of Pharmacology, 1976,
40, 295-302.
28. Davis, M., Cedarbaum, J.M., Aghajanian, G.K., and Gendelman, D.S. Effects
of clonidine on habituation and sensitization of the acoustic startle response in
normal, acutely decerebrate and locus coeruleus lesioned rats.
Psychopharmacology, 1977, 51, 243-253.
29. Sheard, M.H., Astrachan, D.I., and Davis, M. Effects of d-lysergic acid
diethylamide (LSD) upon shock elicited fighting in rats. Life Sciences, 1977,
20, 427-430.
30. Davis, M. and Walters, J.K. Psilocybin: Biphasic dose-response effects on
acoustic startle reflex in the rat. Pharmacology, Biochemistry, and Behavior,
1977, 6, 427-431.
31. Davis, M., Gallager, D.W., and Aghajanian, G.K. Tricyclic antidepressant
drugs: Attenuation of the excitatory effects of d-lysergic acid diethylamide on
the acoustic startle reflex. Life Sciences, 1977, 20, 1249-1258.
32. Sheard, M.H., Astrachan, D.I., and Davis, M. Tricyclic antidepressant drugs:
Antagonism of effect of d-lysergic acid diethylamide on shock-elicited
aggression. Psychopharmacology Communications, 1977, 1, 167-173.
33. Davis, M. and Astrachan, D.I. Conditioned fear and startle magnitude: Effects
of different footshock or backshock intensities used in training. Journal of
Experimental Psychology: Animal Behavior Processes, 1978, 4, 95-103.
34. Walters, J.K., Sheard, M.H., and Davis, M. Effects of N,N-dimethyltryptamine
(DMT) and 5-methoxy-N,N-dimethyltryptamine (5-MeODMT) on shock
elicited fighting in rats. Pharmacology, Biochemistry, and Behavior, 1978, 9,
87-90.
35. Walters, J.K., Davis, M., and Sheard, M.H. Tryptophan free diets: Effects on
the acoustic startle response in rats. Psychopharmacology, 1979, 62, 103-109.
36. Davis, M. Diazepam and flurazepam: Effects on conditioned fear as measured
with the potentiated startle paradigm. Psychopharmacology, 1979, 62, 1-7.
37. Davis, M. Morphine: Effects on conditioned fear as measured with the
potentiated startle paradigm. European Journal of Pharmacology, 1979, 54, 341347.
38. Davis, M., Redmond, D.E. Jr., and Baraban, J.M. Noradrenergic agonists and
antagonists: Effects on conditioned fear as measured by the potentiated startle
paradigm. Psychopharmacology, 1979, 65, 111-118.
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39. Davis, M., Astrachan, D.I., and Kass, E. Excitatory and inhibitory effects of
serotonin on stimulus reactivity measured with acoustic startle. Science, 1980,
209, 521-523.
40. Davis, M., Astrachan, D.I., Gendelman, P.M., and Gendelman, D.S. 5Methoxy-N,N-dimethyltryptamine: spinal cord and brainstem mediation of
excitatory effects on the acoustic startle reflex. Psychopharmacology, 1980, 70,
123-130.
41. Astrachan, D.I. and Davis, M. Spinal modulation of the acoustic startle
response: The role of norepinephrine, serotonin, and dopamine. Brain Research,
1980, 206, 223-228.
42. Davis, M. Habituation and sensitization of a startle-like response elicited by
electrical stimulation at different points in the acoustic startle circuit. Advances
in Physiological Sciences, 1981, 16, 67-78.
43. Davis, M. and Astrachan, D.I. Spinal modulation of acoustic startle: Opposite
effects of clonidine and d-amphetamine. Psychopharmacology, 1981, 75, 219225.
44. Davis, M. Neurochemical modulation of the acoustic startle reflex.
Psychopharmacology Bulletin, 1981, 17, 33-34.
45. Kehne, J.H., Gallager, D.W., and Davis, M. Strychnine: Brainstem and spinal
mediation of excitatory effects on acoustic startle. European Journal of
Pharmacology, 1981, 76, 177-186.
46. Davis, M., Gendelman, D.S., Tischler, M.D., and Gendelman, P.M. A primary
acoustic startle circuit: Lesion and stimulation studies. Journal of Neuroscience,
1982, 2, 791-805.
47. Davis, M., Parisi, T., Gendelman, D.S., Tischler, M.D., and Kehne, J.H.
Habituation and sensitization of electrically elicited 'startle' reflexes. Science,
1982, 218, 688-689.
48. Davis, M. Agonist induced changes in behavior as a measure of functional
changes in receptor sensitivity following chronic antidepressant drugs.
Psychopharmacology Bulletin, 1982, 18, 137-147.
49. Davis, M. and Menkes, D.B. Tricyclic antidepressants vary in decreasing alpha2-adrenergic sensitivity with chronic treatment: Assessment with clonidine
inhibition of acoustic startle. British Journal of Pharmacology, 1982, 77, 217222.
50. Commissaris, R.L. and Davis, M. Opposite effects of N,N-dimethyltryptamine
(DMT) and 5-methoxy-N,N-dimethyltryptamine (5-MeODMT) on acoustic
startle: spinal vs. brain sites of action. Neuroscience Biobehavioral Reviews,
1982, 6, 515-520.
51. Astrachan, D.I., Davis, M., and Gallager, D.W. Behavior and binding:
Correlations between alpha-1-adrenergic stimulation of acoustic startle and
alpha-1-adrenergic occupancy and number in lumbar spinal cord. Brain
Research, 1983, 260, 81-90.
52. Gallager, D.W., Kehne, J.H., Wakeman, E.A., and Davis, M. Developmental
changes in pharmacological responsivity of the acoustic startle reflex: Effects of
picrotoxin. Psychopharmacology, 1983, 79, 87-94.
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53. Tischler, M.D. and Davis, M. A visual pathway that mediates fear-conditioned
enhancement of acoustic startle. Brain Research, 1983, 276, 55-71.
54. Menkes, D.B., Kehne, J.H., Gallager, D.W., Aghajanian, G.K., and Davis, M.
Functional supersensitivity of CNS alpha-1-adrenoceptors following chronic
antidepressant treatment. Life Sciences, 1983, 33, 181-188.
55. Commissaris, R.L. and Davis, M. Excitatory effects of the vasodilator
hydralazine on acoustic startle in the rat. Pharmacology, Biochemistry and
Behavior, 1983, 19, 891-894.
56. Davis, M. Potentiation of startle behavior by anxiety: neural localization and
attenuation by diazepam. Psychopharmacology Bulletin, 1983, 19, 457-465.
57. Marwaha, J., Kehne, J.H., Commissaris, R.L., Lakoski, J.M., Shaw, W., and
Davis, M. Spinal clonidine inhibits neural firing in locus coeruleus. Brain
Research, 1983, 276, 379-382.
58. Astrachan, D.I., Gallager, D.W., and Davis, M. Behavior and binding:
Desensitization to alpha-1-adrenergic stimulation of acoustic startle is
associated with a decrease in alpha-1-adrenoceptor binding sites. Brain
Research, 1983, 276, 183-187.
59. Berg, W.K. and Davis, M. Diazepam blocks fear-enhanced startle elicited
electrically from the brainstem. Physiology and Behavior, 1984, 32, 333-336.
60. Kehne, J.H. and Davis, M. Strychnine increases acoustic startle amplitude but
does not alter short-term or long-term habituation. Behavioral Neuroscience,
1984, 98, 955-968.
61. Berg, W.K. and Davis, M. Associative learning modifies startle reflexes at the
lateral lemniscus. Behavioral Neuroscience, 1985, 99, 191-199.
62. Kehne, J.H. and Davis, M. Central noradrenergic involvement in yohimbine
excitation of acoustic startle: Effects of 6-OHDA and DSP4. Brain Research,
1985, 330, 31-41.
63. Davis, M., Kehne, J.H., and Commissaris, R.L. Antagonism of apomorphine
enhanced startle by alpha-1-adrenergic antagonist. European Journal of
Pharmacology, 1985, 108, 233-241.
64. Davis, M. Cocaine: Excitatory effects on sensorimotor reactivity measured with
acoustic startle. Psychopharmacology, 1985, 86, 31-36.
65. Kehne, J.H., Gallager, D.W., and Davis, M. Spinalization unmask's clonidine
alpha-1-adrenoceptor mediated excitation of the flexor reflex in rats. Journal of
Neuroscience. 1985, 5, 1583-1590.
66. Cassella, J.V. and Davis, M. Fear-enhanced acoustic startle is not attenuated by
acute or chronic imipramine treatment in rats. Psychopharmacology, 1985, 87,
278-282.
67. Harty, T.P. and Davis, M. Cocaine: Effects on acoustic startle and startle
elicited electrically from the cochlear nucleus, Psychopharmacology, 1985, 87,
396-399.
68. Hitchcock, J.M. and Davis, M. Lesions of the amygdala, but not the cerebellum
or red nucleus block fear-enhancement of acoustic startle. Behavioral
Neuroscience, 1986, 100, 11-22.
69. Cassella, J.V. and Davis, M. The design and calibration of a startle
measurement system, Physiology and Behavior, 1986, 36, 377-383
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70. Davis, M., Commissaris, R.L., Cassella, J.V., Yang, S., Dember, L., and Harty,
T.P. Differential effects of dopamine agonists on acoustically and electricallyelicited startle responses, Brain Research, 1986, 371, 58-69.
71. Cassella, J.V. and Davis, M. Habituation, pre-pulse inhibition, fear conditioning
and drug modulation of the acoustically-elicited pinna reflex in rats, Behavioral
Neuroscience, 1986, 100, 39-44.
72. Cassella, J.V., Harty, T.P. and Davis, M. Fear conditioning, pre-pulse inhibition
and drug modulation of a short latency startle response measured
electromyographically from neck muscles in the rat. Physiology and Behavior,
1986, 36, 1187-1191.
73. Davis, M., Cassella, J.V., Wrean, W.H. and Kehne, J.H. Serotonin receptor
subtype agonists: Differential effects on sensorimotor reactivity measured with
acoustic startle. Psychopharmacology Bulletin, 1986, 22, 837-843.
74. Davis, M. Pharmacological and anatomical analysis of fear conditioning using
the potentiated startle paradigm. Behavioral Neuroscience, 1986, 100, 814-824.
75. Kehne, J.H., Astrachan, D.I., Astrachan, E., Tallman, J.F. and Davis, M. The
role of spinal cord cyclic AMP in the acoustic startle response in rats. Journal of
Neuroscience, 1986, 6, 3250-3257.
76. Kehne, J.H., Cassella, J.V., Aghajanian, G.K., Tallman, J.F. and Davis, M.
Pertussis toxin or 8-bromo-cAMP block inhibition of the acoustic startle
response by the a2-adrenergic agonist ST-91. Brain Research, 1987, 406, 87-92.
77. Cassella, J.V. and Davis, M. A technique to restrain awake rats for recording
single-unit activity with glass micropipettes and conventional microdrives. J.
Neuroscience Methods, 1987, 19, 105-113.
78. Hitchcock, J. and Davis, M. Fear-enhanced startle using a tone conditioned
stimulus: effect of amygdala lesions. Physiology and Behavior, 1987, 39, 403408.
79. Davis, M. Mescaline: Excitatory effects on acoustic startle are blocked by
serotonin-2 antagonists. Psychopharmacology, 1987, 93, 286-291.
80. Kehne, J.H., Cassella, J.V. and Davis, M. Anxiolytic effects of buspirone and
gepirone in the fear-potentiated startle paradigm. Psychopharmacology, 1988,
94, 8-13.
81. Davis, M., Cassella, and Kehne, J.H. Serotonin does not mediate anxiolytic
effects of buspirone in the fear-potentiated startle paradigm: comparison with 8OH-DPAT and ipsapirone. Psychopharmacology, 1988, 94, 14-20.
82. Spiera, R.F. and Davis, M. Excitatory amino acid antagonists depress acoustic
startle after infusion into the ventral nucleus of the lateral lemniscus or
paralemniscal zone. Brain Research, 1988, 445, 130-136.
83. Rosen, J.B. and Davis, M. Enhancement of acoustic startle by electrical
stimulation of the amygdala. Behavioral Neuroscience, 102: 195-202, 1988.
84. Davis, M. Apomorphine, d-amphetamine, strychnine and yohimbine do not alter
prepulse inhibition of the acoustic startle reflex. Psychopharmacology, 1988,
95, 151-156.
85. Davis, M. and Gallager, D.W. Continuous slow release of low levels of
diazepam produces tolerance to its depressant and anxiolytic effects on the
startle reflex. European Journal of Pharmacology, 1988, 150, 23-33.
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86. Rosen, J.B. and Davis, M. Temporal characteristics of enhancement of startle
by stimulation of the amygdala. Physiology and Behavior, 1988, 44, 117-123.
87. Yeomans, J.S., Rosen, J.B., Barbeau, J. and Davis, M. Double-pulse stimulation
of startle-like responses in rats: Refractory periods and temporal summation.
Brain Research, 1989, 486, 147-158.
88. Davis, M. Sensitization of the startle reflex by footshock. Behavioral
Neuroscience, 1989, 103, 495-503.
89. Boulis, N.M. and Davis, M. Sensitization by footshock of startle responses
elicited electrically from different points along the acoustic startle pathway.
Behavioral Neuroscience, 1989, 103, 504-508.
90. Hitchcock, J.M., Sananes, C.B. and Davis, M. Sensitization of the startle reflex
by footshock: Blockade by lesions of the central nucleus of the amygdala or its
efferent pathway to the brainstem. Behavioral Neuroscience, 1989, 103, 509518.
91. Davis, M., Commissaris, R.L., Wagner, K.R., Yang, S., Kehne, J.H., Cassella,
J.V., and Boulis, N.M. Spinal vs. supraspinal sites of action of the a2 agonists
clonidine and ST-91 on the acoustic startle reflex. Pharmacology, Biochemistry
& Behavior, 1989, 33, 233-240.
92. Davis, M., Schlesinger, L.S., and Sorenson, C.A. Temporal specificity of fear
conditioning: Effects of different CS-US intervals on the fear-potentiated startle
effect. Journal of Experimental Psychology: Animal Behavioral Processes,
1989, 15, 295-310.
93. Campeau, S. and Davis, M. Reversible neural inactivation by cryogenic
blockade in anesthetized and freely behaving rats. Journal of Neuroscience
Methods, 1990, 32, 25-35.
94. Miserendino, M.J. D., Sananes, C.A., Melia, K.R., and Davis, M. Blocking of
acquisition but not expression of conditioned fear-potentiated startle by NMDA
antagonists in the amygdala. Nature, 1990, 345, 716-718.
95. Davis, M., Mansbach, R.S., Swerdlow, N.R., Campeau, S., Braff, D.L., and
Geyer, M. Apomorphine disrupts the inhibition of acoustic startle induced by
weak prepulses in rats. Psychopharmacology, 1990, 102, 1-4.
96. Boulis, N.M. and Davis, M. Blockade of the spinal excitatory effect of cAMP
on the startle reflex by intrathecal administration of the isoquinoline
sulfonamide H-8: Comparison to the C-kinase inhibitor H-7, Brain Research,
1990, 525, 198-204.
97. Boulis, N.M., Kehne, J.H., Miserendino, M.J.D. and Davis, M. Differential
blockade of early and later components of acoustic startle following intrathecal
infusion of 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) or DL-2-amino-5phosphonovaleric acid (AP5). Brain Research, 1990, 520, 240-246.
98. Rosen, J.B. and Davis, M. Enhancement of electrically elicited startle by
amygdaloid stimulation. Physiology and Behavior, 1990, 48, 343-349.
99. Campeau, S., Liang, K.C., and Davis, M. Long-term retention of fearpotentiated startle following a short training session. Animal Learning and
Behavior, 1990, 18, 462-468.
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100. Melia, K.M. & Davis, M. Effects of septal lesions on fear-potentiated startle
and the anxiolytic effects of buspirone and diazepam. Physiology and Behavior,
1991, 49, 603-612.
101. Rosen, J.B., Hitchcock, J.M., Sananes, C.B., Miserendino, M.J.D. and Davis, M.
A direct projection from the central nucleus of the amygdala to the acoustic
startle pathway: Anterograde and retrograde tracing studies. Behavioral
Neuroscience, 1991, 105, 817-825.
102. Hitchcock, J.M. and Davis, M. Efferent pathway of the amygdala involved in
fear conditioning using the fear-potentiated startle paradigm. Behavioral
Neuroscience, 1991, 105, 826-842.
103. Campeau, S., Hayward, M.D., Hope,B.T., Rosen, J.B., Nestler, E.J. and Davis,
M. Induction of the c-fos proto-oncogene in rat amygdala during unconditioned
and conditioned fear. Brain Research, 1991, 565, 349-352.
104. Grillon, C, Ameli, R., Woods, S., Merikangas, K. and Davis, M. Fearpotentiated startle in humans: Effect of anticipatory anxiety on the acoustic blink
reflex. Psychophysiology, 1991, 28, 588-595.
105. Kehne, J.H., Boulis, N.M. and Davis, M. Effects of the phosphodiesterase
inhibitor rolipram on the acoustic startle reflex. Psychopharmacology, 1991,
105, 27-36.
106. Sananes, C.B. and Davis, M. NMDA lesions of the lateral and basolateral nuclei
of the amygdala block fear-potentiated startle and shock sensitization of startle.
Behavioral Neuroscience, 1992, 106, 72-80.
107. Melia, K. R., Sananes, C.B. and Davis, M. Lesions of the central nucleus of the
amygdala block the excitatory effects of septal ablation on the acoustic startle
reflex. Physiology & Behavior, 1991, 51, 175-180.
108. Falls, W.A., Miserendino, M.J.D., and Davis, M. Extinction of fear-potentiated
startle: Blockade by infusion of an NMDA antagonist into the amygdala.
Journal of Neuroscience, 1992, 12, 854-863.
109. Campeau, S. and Davis, M. Fear potentiation of the acoustic startle reflex using
noises of various spectral frequencies as conditioned stimuli. Animal Behavioral
and Learning, 1992, 20, 177-186.
110. Campeau, S., Miserendino, M.J.D. and Davis, M. Intra-amygdala infusion of
the N-methyl-D-aspartate receptor antagonist AP5 blocks acquisition but not
expression of fear-potentiated startle to an auditory conditioned stimulus.
Behavioral Neuroscience, 1992, 106, 569-574.
111. Liang, K.C., Melia, K.R., Miserendino, M.J.D., Falls, W. A ., Campeau, S. and
Davis, M. Corticotropin-Releasing Factor: Long-lasting facilitation of the
acoustic startle reflex. Journal of Neuroscience, 1992, 12, 2303-2312.
112. Liang, K.C., Melia, K.R., Campeau, S., Falls, W. A ., Miserendino, M.J.D., and
Davis, M. Lesions of the central nucleus of the amygdala, but not the
paraventricular nucleus of the hypothalamus block the excitatory effects of
corticotropin-releasing factor on the acoustic startle reflex. Journal of
Neuroscience,1992, 12, 2313-2320
113. Melia, K.R., Falls, W.A., & Davis, M. Involvement of pertussis toxin sensitivie
G-proteins in conditioned fear-potentiated startle: Possible involvement of the
amygdala. Brain Research,1992, 584, 141-148.
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114. Rosen, J.B., Hitchcock, J.M., Miserendino, M.J.D., Falls, W A., Campeau, S.
and Davis, M. Lesions of the perirhinal cortex, but not of the frontal, medial
pre-frontal, visual or insular cortex block fear-potentiated startle using a visual
conditioned stimulus. Journal of Neuroscience, 1992, 12, 4624-4633.
115. Morgan, C.A., Southwick, S.M., Grillon, C., Davis, M., Krystal, J.H. and
Charney, D.S. Yohimbine facilitated acoustic startle reflex in humans.
Psychopharmacology, 1993, 110, 342-346.
116. Kim, M., Campeau, S,. Falls, W.A., and Davis, M. Intra-amygdala infusions of
the non-NMDA receptor antagonist CNQX blocks the expression of fearpotentiated startle. Behavioral and Neural Biology, 1993, 59, 5-8.
117. Grillon, C., Ameli, R,. Foot, M. & Davis, M. Fear-potentiated startle:
Relationship to the level of state/trait anxiety in healthy subjects. Biological
Psychiatry, 1993, 33, 566-574.
118. Kim, M. & Davis, M. Electrolytic lesions of the amygdala block acquisition and
expression of fear-potentiated startle even with extensive training, but do not
prevent re-acquisition. Behavioral Neuroscience, 1993, 107, 580-595.
119. Grillon, C., Ameli, R., Woods, S.W. and Davis, M. Measuring the time course
of anticipatory anxiety using the fear-potentiated startle reflex.
Psychophysiology, 1993, 30, 430-346.
120. Falls, W.A. and Davis, M. Visual cortex ablations do not prevent extinction of
fear-potentiated startle using a visual conditioned stimulus. Behavioral and
Neural Biology, 1993, 60, 259-270.
121. Miserendino, M.J.D and Davis, M. NMDA and non-NMDA antagonists infused
into the nucleus reticularis pontis caudalis depress the acoustic startle reflex.
Brain Research, 1993, 623, 215-222.
122. Kim, M. and Davis, M. Lack of a temporal gradient of retrograde amnesia in
rats with amygdala lesions assessed with the fear-potentiated startle paradigm.
Behavioral Neuroscience, 1993, 107, 1088-1092.
123. Grillon, C., Falls, W.A., Rezvan, A., and Davis, M. Safety signals and human
anxiety: A Fear-potentiated startle study. Anxiety, 1994, 1, 13-21.
124. Grillon, C., Ameli, R,. Goddard, A., Woods, S.W.and Davis, M. Baseline and
fear-potentiated startle in panic disorder patients. Journal of Biological
Psychiatry, 1994, 35, 431-439.
125. Liang, K.C., Hon, W., and Davis, M. Pre- and post-training intra-amygdala
infusions of N-methyl-d-aspartate receptor antagonists impair memory in an
inhibitory avoidance task. Behavioral Neuroscience, 1994, 108, 241-253.
126. Davis, M., Hitchcock, J.M., Bowers, M.B., Berridge, C.W., Melia, K.R., and
Roth, R. H. Stress induced activation of prefrontal cortex dopamine turnover:
Blockade by lesions of the amygdala. Brain Research, 1994, 664, 207-210.
127. Falls, W. A. and Davis, M. Fear-potentiated startle using three conditioned
stimulus modalities. Animal Learning and Behavior, 1994, 22, 379-383.
128. Lee, Y., Schulkin, J. and Davis, M. Effect of corticosterone on the enhancement
of the acoustic startle reflex by corticotropin releasing factor. Brain Research,
1994, 666, 93-98.
129. Grillon, C. and Davis, M. Effect of anticipatory anxiety induced by the threat of
shock on prepulse inhibition. Psychophysiology, 1994, 31, 53-55.
13
130. Campeau, S. and Davis, M. Involvement of the central nucleus and basolateral
complex of the amygdala in fear conditioning measured with fear-potentiated
startle in rats trained concurrently with auditory and visual conditioned stimuli.
Journal of Neuroscience, 1995, 15, 2301-2311.
131. Campeau, S. and Davis, M. Involvement of subcortical and cortical lateral
amygdala afferents in fear conditioning measured with fear-potentiated startle in
rats trained concurrently with auditory and visual conditioned stimuli. Journal
of Neuroscience, 1995, 15, 2312-2327.
132. Campeau, S. and Davis, M. Prepulse inhibition of the acoustic startle reflex
using visual and auditory prepulses: Disruption by apomorphine.
Psychopharmacology, 1995, 117, 267-274.
133. Falls, W. A. and Davis, M. Lesions of the central nucleus of the amygdala block
conditioned excitation, but not conditioned inhibition of fear as measured with
the fear-potentiated startle effect Behavioral Neuroscience, 1995, 109, 379-387.
134. Gewirtz, J.C. and Davis, M. Habituation of prepulse inhibition of the startle
reflex using a weak auditory prepulse. Behavioral Neuroscience, 1995, 109,
388-395
135. deLima, T. C. M. and Davis, M. Involvement of cyclic AMP at the level of the
nucleus reticularis pontis caudalis in the acoustic startle reflex. Brain Research,
1995, 700, 59-69
136. Morgan, C. A., Grillon, C., Southwick, S. M., Davis, M., and Charney, D.S.
Fear-potentiated startle in posttraumatic stress disorder, Biological Psychiatry,
1995, 38, 378-385.
137. Morgan, C. A., Grillon, C., Southwick, S. M.,Nagy, L.M., Davis, M., Krystal, J.
H. and Charney, D.S. Yohimbine facilitated acoustic startle in combat veterans
with posttraumatic stress disorder, Psychopharmacology, 1995, 117, 466-471.
138. Grillon, C. and Davis, M. Acoustic startle and anticipatory anxiety in humans:
Effects of monaural right and left ear stimulation, Psychophysiology, 1995, 32,
155-161
139. Lee, Y., Lopez, D.E., Meloni, E.G. and Davis, M. A primary acoustic startle
pathway: Obligatory role of cochlear root neurons and the nucleus reticularis
pontis caudalis. Journal of Neuroscience, 1996, 16, 3777-3789
140. Lee, Y., Walker, D. and Davis, M. Lack of a temporal gradient of retrograde
amnesia following NMDA-induced lesions of the basolateral amygdala assessed
with the fear-potentiated paradigm. Behavioral Neuroscience, 1996, 110, 836839.
141. Grillon, C., Morgan, C.A., Southwick, S.M., Davis, M., and Charney, D.S.
Baseline startle amplitude and prepulse inhibition in Vietnam veterans with
PTSD. Psychiatry Research , 1996, 64, 169-178.
142. McNish, K. and Davis, M. The effects of olfactory bulbectomy on the acoustic
startle reflex and its modulation by stress. Behavioral Neuroscience, 1997, 111,
80-91.
143. Falls, W. A. and Davis, M. Inhibition of fear-potentiated startle can be detected
after the offset of a feature trained in a serial feature negative discrimination.
Journal of Experimental Psychology: Animal Behavioral Processes, 1997, 23, 314.
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144. Campeau, S., Falls, W.A., Cullinan, W.E., Helmreich, D.L., Davis, M. and
Watson, S.J. Elicitation and reduction of fear: Behavioral and neuroendocrine
indices and brain induction of the immediate-early gene c-fos. Neuroscience ,
1997, 78, 1087-1104.
145. Morgan, C. A., Grillon, C., Southwick, S. M., Davis, M., and Charney, D.S.
Exaggerated acoustic startle in gulf war veterans with post traumatic stress
disorder. American Journal of Psychiatry, 1996, 153, 64-68.
146. Gewirtz, J. C. and Davis, M. Second order fear conditioning prevented by
blocking NMDA receptors in the amygdala. Nature, 1997, 388, 471-474.
147. Lee, Y. and Davis, M. Role of the septum in the excitatory effect of
corticotropin releasing (CRH) hormone on the acoustic startle reflex. Journal of
Neuroscience, 1997, 17, 6424-6433.
148. Lee, Y. and Davis, M. Role of the hippocampus, bed nucleus of the stria
terminalis and amygdala in the excitatory effect of corticotropin releasing
(CRH) hormone on the acoustic startle reflex. Journal of Neuroscience, 1997,
17, 6434-6446.
149. Gewirtz, J. C. Falls, W.A., and Davis, M. Normal conditioned inhibition and
extinction of freezing and fear-potentiated startle following electrolytic lesions
of the medial frontal cortex. Behavioral Neuroscience, 1997, 111, 712-726.
150. Walker, D. L. and Davis, M. Involvement of the dorsal periacqueductal gray in
the loss of fear-potentiated startle accompanying high footshock training.
Behavioral Neuroscience, 1997, 111, 692-702.
151. Grillon, C. and Davis, M. Fear-potentiated startle conditioning in humans:
Effects of explicit and contextual cue conditioning following paired vs. unpaired
training Psychophysiology, 1997, 34, 451-458.
152. Walker, D. L. and Davis, M. Anxiogenic effects of high illumination levels
assessed with the acoustic startle response. Biological Psychiatry, 1997, 42,
461-471.
153. Grillon, C., Pellowski, M., Merikangas, K.R. and Davis, M. Darkness facilitates
the acoustic startle reflex in humans. Biological Psychiatry, 1997, 42, 453-460.
154. Krystal, J.H., Webb, E., Grillon, C., Cooney, N., Casal, L., Morgan, C.A.,
Southwick, S.M., Davis, M., Charney, D.S. Evidence of acoustic startle
hyperreflexia in recently detoxified alcoholics early onset male alcoholics:
modulation by yohimbine and m-chlorophenylpiperazine (mCPP).
Psychopharmacology, 1997, 131, 207-215.
155. Walker, D. L. and Davis, M. Double dissociation between the involvement of
the bed nucleus of the stria terminalis and the central nucleus of the amygdala in
light-enhanced versus fear-potentiated startle. Journal of Neuroscience, 1997,
17, 9375-9383.
156. McNish, K.A., Gewirtz, J.C. and Davis, M. Evidence of contextual fear
conditioning following lesions of the hippocampus: A disruption of freezing but
not fear-potentiated startle. Journal of Neuroscience, 1997, 17, 9353-9360
157. Pelton, G.H., Lee, Y., and Davis, M. Repeated stress, like vasopressin,
sensitizes the excitatory effects of corticotropin releasing factor on the acoustic
startle reflex. Brain Research, 1997, 778, 381-387.
15
158. Birnbaum, S. and Davis, M. Modulation of the acoustic startle reflex by
infusion of corticotropin releasing hormone into the nucleus reticularis pontis
caudalis. Brain Research, 1998, 782, 318-323.
159. Gewirtz, J.C., McNish, K.A. and Davis, M. Lesions of the bed nucleus of the
stria terminalis block sensitization of the acoustic startle reflex produced by
repeated stress, but not fear-potentiated startle. Progress in NeuroPsychopharmacology and Biological Psychiatry, 1998, 22, 625-648.
160. Gewirtz, J.C. and Davis, M. Application of Pavlovian higher-order conditioning
to the analysis of the neural substrates of learning and memory.
Neuropharmacology, 1998, 37, 453-460.
161. Grillon, C. and Davis, M. Effects of stress and shock anticipation on prepulse
inhibition of the startle reflex. Psychophysiology, 1997, 34, 511-517.
162. Grillon, C., Morgan, C.A., Davis, M., and Southwick, S.M. Effect of darkness
on acoustic startle in Vietnam Veterans with PTSD. American Journal of
Psychiatry, 1998, 155, 812-817.
163. Meloni, E.G. and Davis, M. The dorsal cochlear nucleus contributes to a high
intensity component of acoustically elicited startle but is not involved in
background noise facilitation, habituation, prepulse inhibition or facilitation or
fear potentiated startle in rats. Hearing Research, 1998, 119, 69-80.
164. Shi, C.-J., & Davis, M. Pain pathways involved in fear conditioning measured
with fear-potentiated startle: lesion studies. Journal of Neuroscience, 1999, 19,
420-430.
165. Grillon, C. Morgan, C.A., Davis, M. and Southwick, S.M. Effects of
experimental context and explicit threat cues on acoustic startle in Vietnam
Veterans with posttraumatic stress disorder. American Journal of Psychiatry,
1998, 44, 1027-1036
166. Meloni, E. and Davis, M. Enhancement of the acoustic startle reflex in rats by
the dopamine D1 agonists SKF 82958. Psychopharmacology, 1999, 144, 373380.
167. Meloni, E. G. and Davis, M. Muscimol in the deep layers of the superior
colliculus/mesencephalic reticular formation blocks expression but not
acquisition of fear-potentiated startle in rats. Behavioral Neuroscience, 1999,
113, 1152-1160
168. Gewirtz, J. C., McNish, K.A. and Davis, M. Disruption of contextual freezing,
but not contextual "blocking" of fear-potentiated startle after lesions of dorsal
hippocampus. Behavioral Neuroscience, 2000, 114, 64-76.
169. Meloni, E. G Davis, M. GABA in the deep layers of the superior colliculus
mediates the enhancement of startle by the dopamine D1 receptor agonist SKF
82958. Journal of Neuroscience, 2000, 20: 5374-5381.
170. Meloni EG, Davis M. Synergistic enhancement of the acoustic startle reflex by
dopamine D1 and 5-HT1A agonists and corresponding changes in c-Fos
expression in the dorsal raphe of rats. Psychopharmacology, 2000, 151, 359-367
171. Meloni EG, Davis M. Enhancement of the acoustic startle response by
dopamine agonists after 6-hydroxydopamine lesions of the substantia nigra pars
compacta: corresponding changes in c-Fos expression in the caudate-putamen.
Brain Research, 2000, 879, 93-104.
16
172. Walker, D.L. and Davis, M. Involvement of N-methyl-D-aspartate (NMDA)
receptors within the amygdala in short- versus long-term memory for fear
conditioning as assessed with fear-potentiated startle. Behavioral Neuroscience,
2000, 114, 1019-1033
173. Josselyn, S.A., Carlezon Jr., W.A., Shi, C-J., Neve, R.L., Nestler, E.J., Davis, M.
Memory Facilitation by CREB: Overexpression in the amygdala increases fear
conditioning. Journal of Neuroscience, 2001 21, 2404-2412
174. Phelps, E. A., O’Connor, K J., Grillon, C.,. Gatenby, J. C, Gore, J.C., and
Davis, M. Activation of the human amygdala to a cognitive representation of
fear. Nature Neuroscience, 2001, 4, 437-441.
175. Funayama, E.S., Grillon, C., Davis, M. and Phelps, E.A. A. A double
dissociation in the affective modulation of startle in humans: Effects of
unilateral temporal lobectomy Cognitive Neuroscience, 2001,13, 1-10.
176. Lu, K-T., Walker, D.L. and Davis, M. Mitogen-activated protein kinase cascade
in the basolateral nucleus of amygdala is essential for the extinction of fearpotentiated startle. Journal of Neuroscience, 2001, 21, RC 162
177. Shi, C-J. and Davis, M. Visual pathways involved in fear conditioning
measured with fear-potentiated startle: Behavior and anatomic studies. Journal
of Neuroscience. 2001, 21, 9844-9855
178. Paschall, G.Y. and Davis, M. Olfactory mediated fear potentiated startle.
Behavioral Neuroscience, 2002, 116, 4-12.
179. Walker, D.L. and Davis, M. Light enhanced startle: Further pharmacological
and behavioral evaluation. Psychopharmacology, 2002, 159, 303-310
180. Walker, D. L. and Davis, M. The role of glutamate receptors within the
amygdala in fear learning, fear-potentiated startle, and extinction.
Pharmacology, Biochemistry and Behavior, 2002, 71, 379-392
181. Walker, D. L., Ressler, J.K., Lu, K.-T., & Davis, M. Facilitation of conditioned
fear extinction by systemic administration or intra amygdala infusions of dcycloserine as assessed with fear-potentiated startle in rats. Journal of
Neuroscience, 2002, 22, 2343-2351
182. Winslow, J. T., Parr, L. A., & Davis, M. Acoustic startle, prepulse inhibition and
fear-potentiated startle measured in rhesus monkeys. 2002, Biological
Psychiatry, 51, 859-866.
183. Parr, L. A., Winslow, J. T., & Davis, M. Rearing experience differentially
affects somatic and cardiac startle responses in rhesus monkeys (Macaca
mulatta). 2002, Behavioral Neuroscience, 116, 378-86.
184. Ressler, K. J., Paschall, G. Y., Zhao, X. L., & Davis, M. Induction of synaptic
plasticity genes in a distributed neural circuit during consolidation of
conditioned fear learning. Journal of Neuroscience, 2002, 22, 7892-7903.
185. Paschall, G. and Davis, M. Second-order olfactory-mediated fear-potentiated
startle. Learning and Memory, 2002, 9, 395-401.
186. Walker, D.L, Rattiner, L. and Davis, M. Group II metabotropic glutamate
receptors within the amygdala regulate anxiety in rats as assessed with fearpotentiated startle. Behavioral Neuroscience, 2002, 116, 1075-1083.
17
187. Walker, D.L. and Davis, M. Quantifying fear potentiated startle using absolute
versus percent increase scoring methods: Implications for the neurocircuitry of
fear and anxiety. Psychopharmacology, 2002 164, 318-28.
188. Southwick S.M., Davis M., Horner B., Cahill L., Morgan C.A., 3rd, Gold P.E.,
Bremner J.D., and Charney D.C. Relationship of enhanced norepinephrine
activity during memory consolidation to enhanced long-term memory in
humans. American Journal of Psychiatry 2002, 159:1420-1422.
189. Meloni E.G., Davis M. The substantia nigra pars reticulata mediates the
enhancement of startle by the dopamine D1 receptor agonist SKF 82958.
Psychopharmacology, 2004, 174, 228-236.
190. Myers, K., Goulet, M., Rusche, J., Boismenu, R. and Davis, M., Inhibition of
fear potentiated startle in rats following peripheral administration of secretin,
2004, Psychopharmacology (Berl), 172 94-9.
191. Grillon, C., Cordova, J., Morgan, C.A., 3rd, Charney, D.S. and Davis, M.,
Effects of the beta-blocker propranolol on cued and contextual fear conditioning
in humans, Psychopharmacology (Berl), 2004, 175, 342-52.
192. Rattiner, L.M., Davis, M. Ressler, K.J. BDNF and TrkB receptor involvement in
amygdala dependent fear conditioning. Journal of Neuroscience, 2004, 24:
4796-4806.
193. Myers, K.M. and Davis, M. AX+, BX- discrimination learning in the fearpotentiated startle paradigm: Possible relevance to inhibitory fear learning in
extinction. Learning and Memory, 2004, 11, 464-75.
194. Levita, L. Hammack, S.E., Mania, I., Li, X-Y, Davis, M. Rainnie, D.G. 5HT1A-like Receptor activation in the bed nucleus of the stria terminalis:
electrophysiological and acoustic startle effects, Neuroscience, 2004, 128, 583596.
195. Jasnow, A. M., Davis, M., & Huhman, K. L. Involvement of central amygdalar
and bed nucleus of the stria terminalis corticotropin-releasing factor in
behavioral responses to social defeat. Behavioral Neuroscience, 2004, 118,
1052-61.
196. Toufexis, D. J., Davis, C., Hammond, A., & Davis, M. Progesterone attenuates
corticotropin-releasing factor-enhanced but not fear-potentiated startle via the
activity of its neuroactive metabolite, allopregnanolone. Journal of
Neuroscience, 2004, 24, 10280-7.
197. Zhao, Z., & Davis, M. Fear-potentiated startle in rats is mediated by
neurons in the deep layers of the superior colliculus/deep
mesencephalic nucleus of the rostral midbrain through the glutamate
non-NMDA receptors. Journal of Neuroscience, 2004, 24, 10326-34.
198. Ressler, K. J., Rothbaum, B. O., Tannenbaum, L., Anderson, P.,
Zimand, E., Hodges, L., & Davis, M. Cognitive enhancers as adjuncts
to psychotherapy: Use of D-cycloserine in phobics to facilitate
extinction of fear. Archives of General Psychiatry, 2004, 61, 11361144.
199. Josselyn, S.A., Falls, W.A., Gewirtz, J.C. Pistell, P. and Davis, M.
The nucleus accumbens is not critically involved in conditioned
18
inhibition of fear-potentiated startle. Neuropsychopharmacology,
2005, 30, 17-26.
200. Chhatwal, J.P., Myers, K.M., Ressler, K.J., Davis, M. Regulation of gephyrin
and GABAA receptor binding within the amygdala after fear acquisition and
extinction. Journal of Neuroscience, 2005, 25:502-506.
201. Chhatwal, J.P., Davis, M, Maguschak, K.A, Ressler, K.J (2005)
Enhancing cannabinoid neurotransmission augments the extinction of
conditioned fear. Neuropsychopharmacology 2005, 30:516-524.
202. Jones, S.V., Heldt, S.A., Davis, M, and Ressler, K.J. Olfactory-cued fear
conditioning in mice, measured simultaneously with fear-potentiated startle and
freezing. Behavioral Neuroscience. 2005, 119:329-335.
203. Rattiner, L., Davis, M. and Ressler, K.J. Differential regulation of brain-derived
neurotrophic factor transcripts following fear learning. Learning and Memory,
2005,11:727-731.
204. Sanchez MM, Noble PM, Lyon CK, Plotsky PM, Davis M, Nemeroff CB,
Winslow JT. Alterations in diurnal cortisol rhythm and acoustic startle response
in nonhuman primates with adverse rearing. Biological Psychiatry 2005, 57:373381.
205. Walker DL, Paschall GY, Davis M. Glutamate receptor antagonist infusions into
the basolateral and medial amygdala reveal differential contributions to
olfactory vs. context fear conditioning and expression. Learning and Memory,
2005, 12:120-129.
206. Jovanovic, T., Keyer, M., Fiallos, A., Myers, K.M., Davis, M., Duncan, E.J.
Fear potentiation and fear inhibition in a human fear-potentiated startle
paradigm. Biological Psychiatry, 2005, 57, 1559-1564.
207. Toufexis, D. Davis, C. Hammond, A. and Davis. M. Sex-differences in
hormonal modulation of anxiety measured with light enhanced startle: Possible
role for arginine vasopressin in the male (2005). Journal of Neuroscience, 25,
9010-9016.
208. Jasnow, A.M., Shi, C-J, Israel, J.E., Davis, M., Huhman, K.L. Memory of social
defeat is facilitated by cAMP response element-binding protein overexpression
in the amygdala (2005). Behavioral Neuroscience, 119, 1125-1130.
209. Nair, H.P., Gutman, A., Davis, M. and Young, L. (2005) Central oxytocin, vasopressin and
corticotropin releasing factor receptor densities in the basal forebrain predict coping with social
stress. Journal of Neuroscience, 25, 11479-11488.
210. Zhao Z, Krishnaney A, Teng Q, Yang J, Garrity-Moses M, Liu JK,
Venkiteswaran, K, Subramanian, T, Davis, M and NM Boulis, NM. (2006):
Anatomically discrete functional effects of adenoviral clostridial light chain
gene-based synaptic inhibition in the midbrain. Gene Therapy, 1-11.
211. Chhatwal, J. P., Stanek-Rattiner, L., Davis, M., & Ressler, K. J. (2006). Amygdala
BDNF signaling is required for consolidation but not encoding of extinction. Nature
Neuroscience, 9(7), 870-872.
212. Winslow, J. T., Noble, P. L., & Davis, M. (2006). Modulation of Fear-Potentiated
Startle and Vocalizations in Juvenile Rhesus Monkeys by Morphine, Diazepam, and
Buspirone. Biological Psychiatry, 61, 389-395.
213. Myers, K. M., Ressler, K. J., & Davis, M. (2006). Different mechanisms of fear
19
214.
215.
216.
217.
218.
219.
220.
221.
222.
223.
224.
225.
226.
extinction dependent on length of time since fear acquisition. Learning and Memory,
13, 216-223.
Norrholm, S. D., Jovanovic, T., Vervliet, B., Myers, K. M., Davis, M., Rothbaum, B.
O., & Duncan, E. J. (2006). Conditioned fear extinction and reinstatement in a human
fear-potentiated startle paradigm. Learning and Memory, 13, 681-685.
Antoniadis, E.A., Winslow, J.W., Davis, M. and Amaral, D.G. (2007). Role of
the primate amygdala in fear-potentiated startle: effects of chronic lesions in the
rhesus monkey. Journal of Neuroscience, 27, 7386-7396.
Toufexis, D.J., Myers, K.M., Bowser, M.E. and Davis, M. (2007). Estrogen
disrupts the inhibition of fear in female rats, possibly through the antagonistic
effects of estrogen receptor (ER) and ERß. Journal of Neuroscience, 27, 97299735.
Jovanovic, T, Norrholm S.D., Keyes M., Fiallos A., Jovanovic S., Myers K.M.,
Davis M., Duncan E.J. (2006) Contingency awareness and fear inhibition in a
human fear-potentiated startle paradigm. Behavioral Neuroscience 120,9951004.
Jones, S.V., Stanek-Rattiner, L., Davis, M. and Ressler, K.J. (2007) Differential
regional expression of brain-derived neurotrophic factor following olfactory fear
learning. Learning and Memory, 14, 816-820.
Winslow, J.T., Noble, P.L. and Davis, M. (2008). AX+/BX- discrimination
learning in the fear-potentiated startle paradigm in monkeys. Learning and
Memory, 15, 63-66.
Walker, D.L. and Davis, M. (2008). Amygdala infusions of an NR2B-selective
or an NR2A-preferring NMDA receptor antagonist differentially influence fear
conditioning and expression in the fear-potentiated startle test. Learning and
Memory, 15, 67-77.
Glover, E. M. and Davis, M. (2008) Anxiolytic effects of morphine and buprenorphine
the fear-potentiated startle: Tolerance, cross tolerance and blockade by naloxone.
Psychopharmacology (Berl) 198:167-180.
Norrholm, S.D., Bram Vervliet, B. Jovanovic, T. Boshoven. W., Myers, K.M.,
Davis, M. Barbara O. Rothbaum, B.O, and Duncan, E. J. (2008) Timing of
extinction relative to acquisition: A parametric analysis of fear extinction in
humans. Behavioral Neuroscience, 122, 1016-30.
Jones, S.V., Davis, M., Ressler, K.J. (2008) Learning dependent structural plasticity in
the adult olfactory sensory neuron projection. Journal of Neuroscience, 28: 1310613111.
Gutman AR, Yang Y, Ressler KJ, Davis M (2008) The role of neuropeptide Y in the
expression and extinction of fear-potentiated startle. Journal of Neuroscience 28:1268212690.
Zhao Z, Yang Y, Walker DL, Davis M (2009) Effects of substance p in the amygdala,
ventromedial hypothalamus, and periaqueductal gray on fear-potentiated startle.
Neuropsychopharmacology 34:331-340.
Chhatwal, J.P. Gutman, A.R. Maguschak, K.A. Davis, M. and Ressler, K.J
(2009) Functional interactions between the endocannabinoid and CCKergic
neurotransmitter systems may be critical for extinction learning.
Neuropsychopharmacology, 34, 509-21.
20
227. Keen-Rhinehart E, Michopoulos V, Toufexis DJ, Martin EI, Nair H, Ressler KJ, Davis
M, Owens MJ, Nemeroff CB, Wilson ME (2009) Continuous expression of
corticotropin-releasing factor in the central nucleus of the amygdala emulates the
dysregulation of the stress and reproductive axes. Molecular Psychiatry 14:37-50.
228. Jovanovic, T., Norrholm, S.D.,, Fennell, J.E.. Keyes, M., Fiallos, A.M.,, Myers,
K.M., Davis, M.,, Duncan, E.J. (2009) Posttraumatic stress disorder may be
associated with impaired fear inhibition: relation to symptom severity.
Psychiatry Research, 167, 151-60
229. Antoniadis, E.A., Winslow, J.W., Davis, M. and Amaral, D.G. (2009) The nonhuman primate amygdala is necessary for the acquisition but not the retention of
fear-potentiated startle: Effects of chronic amygdala lesions in the rhesus
monkey. Biological Psychiatry 65: 241-8
230. Walker, D. L., Yang, Y., Ratti, E., Corsi, M.,Trist, and Davis, M. (2009). Oral
administration of the CRF-R1 antagonist GSK008 disrupts bed nucleus of the
stria terminalis dependent light-enhanced startle, but spares central nucleus of
the amygdala dependent fear-potentiated startle. Neuropsychopharmacology,
34, 1533-42
231. Henry, K. P., Davis, M., & Howell, L. L. (2009). Effects of cocaine selfadministration history under limited and extended access conditions on in vivo
striatal dopamine neurochemistry and acoustic startle in rhesus monkeys.
Psychopharmacology (Berl), 205, 237-247
232. Jovanovic, T., Norrholm, S.D., Blanding, N.Q., Davis, M., Duncan, E.,
Bradley,B., Ressler, K. (2010). Impaired fear inhibition is a biomarker of PTSD
but not depression. Depression and Anxiety, 27, 244-251
233. Jovanovic, T., Norrholm, S. D., Blanding, N. Q., Phifer, J. E., Weiss, T., Davis, M.,
Duncan, E., Bradley, B., & Ressler, K. (2010). Fear potentiation is associated with
hypothalamic-pituitary-adrenal axis function in PTSD. Psychoneuroendocrinology, 35,
846-857.
234. Heldt, S.A., Davis, M., Ratti, E, Corsi, M.,Trist, and Ressler, K.J. (2009)
Anxiolytic-like effects of the neurokinin 1 receptor antagonist GR-205171in the
elevated plus maze and contextual fear potentiated startle model of anxiety.
Behavioral Pharmacology, 20, 584-595
235.
Reviews and Chapters
1. Heninger, G.R. and Davis, M. Delayed effects of lithium on somatosensory
evoked response and acoustic startle reflexes in cats and monkeys. In: Lithium
Current Controversies and Unresolved Issues. S. Gerson, M. Schou, and N.S.
Kline (Eds), Excerpta Medica: Amsterdam, 1979, pp. 841-853.
2. Davis, M. Neurochemical modulation of sensory-motor reactivity: Acoustic and
tactile startle reflexes. Neuroscience Biobehavioral Reviews, 1980, 4, 241-263.
3. Davis, M. and File, S.E. Intrinsic and extrinsic habituation and sensitization:
implications for the design and interpretation of experiments. In: Habituation in
21
the Behaving Organism. H.V.S. Peeke and L. Petrinovich (Eds), Academic Press:
New York, 1984, pp.287-323.
4. Davis, M., Kehne, J.H., Commissaris, R.L., and Geyer, M.A. Effects of
hallucinogens on unconditioned behaviors in animals. In: Hallucinogens:
Neurochemical, Behavioral and Clinical Perspectives. Raven Press: New York,
1984, pp.35-75.
5. Davis, M., Astrachan, D.I., Kehne, J.H., Commissaris, R.L., and Gallager, D.W.
Catecholamine modulation of sensorimotor reactivity measured with acoustic
startle. In: Catecholamines: Neuropharmacology and Central Nervous System Theoretical Aspects. Alan R. Liss, Inc.: New York, 1984, pp. 245-258.
6. Davis, M. The mammalian startle response. In: Neural Mechanisms of Startle
Behavior. R.C. Eaton (Ed), Plenum Publishing Corporation: New York, 1984,
pp.287-351.
7. Davis, M., Kehne, J.H., Cassella, J.V. and Commissaris, R.L. a1- and a2adrenergic modulation of sensorimotor reactivity measured with the acoustic
startle reflex. In: Epinephrine in the Central Nervous System, J. Stolk (Ed),
Oxford University Press, New York, 1988, pp.270-281.
8. Davis, M., Hitchcock, J.M., and Rosen, J.B. Anxiety and the amygdala:
Pharmacological and anatomical analysis of the fear-potentiated startle paradigm.
In: The Psychology of Learning and Motivation: Advances in Research and
Theory, G.H. Bower (Ed.), Academic Press Inc., San Diego, 1987, pp.263-305.
9. Davis, M. The potentiated startle response as a measure of conditioned fear and
its relevance to the neurobiology of anxiety. In: Selected Models of Anxiety,
Depression and Psychosis, (Eds.) P. Simon, P. Soubrie & D. Widlocher, Karger
AG, Basel, Switzerland, 1988, pp.61-89.
10. Davis, M. Cassella, J.V. and Kehne, J.H. Serotonergic modulation of
sensorimotor reactivity and conditioned fear as measured with the acoustic startle
reflex. In: 5-HT Agonists and Psychoactive Drugs, R.H. Rech and G.A.
Gudelsky (Eds), 1988, NPP Books, Ann Arbor, pp. 163-184.
11. Davis, M. The role of the amygdala and its efferent projections in fear and
anxiety. In: Psychopharmacology of Anxiety, Oxford University Press, Oxford,
1989, pp.52-79.
12. Davis, M. Neural systems involved in fear-potentiated startle. In "Modulation of
Defined Vertebrate Neural Circuits, M. Davis, B.L. Jacobs, R.I. Schoenfeld (Eds),
Annals of the New York Academy of Sciences, 563, 1989, pp.165-183.
13. Davis, M. Pharmacological and anatomical analysis of fear conditioning. In:
"Neurobiology of Drug Abuse: Learning and Memory". National Institute on
Drug Abuse Research Monograph 97, 1990, pp.126-165.
14. Davis, M. Animal models of anxiety based on classical conditioning: The
conditioned emotional response (CER) and the fear-potentiated startle effect.
Pharmacology and Therapeutics, 1990, 47, 147-165.
15. Davis, M. Animal models of anxiety based on classical conditioning: The
conditioned emotional response (CER) and the fear-potentiated startle effect. In:
The International Encyclopedia of Pharmacology and Therapeutics, S.E. File
(Ed), Pergamon Press, New York, 1991, pp.187-212.
22
16. Davis, M., Hitchcock, J.M., and Rosen, J.B. Neural mechanisms of fear
conditioning measured with the acoustic startle reflex. In: Neurobiology of
Learning, Emotion, and Affect, J. Madden IV, (Ed), Raven Press, Ltd.: New
York, 1991, pp.67-95.
17. Davis, M. The role of the amygdala in fear and anxiety. In: The Annual Review
of Neuroscience, 15, 1992, 353-375.
18. Davis, M. The role of the amygdala in conditioned fear. In: The Amygdala:
Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction (John
Aggleton, Ed), Wiley-Liss, Inc.: New York, 1992, pp.255-305.
19. Davis, M. The role of the amygdala in fear-potentiated startle: Implications for
animal models of anxiety. Trends in Pharmacological Sciences, 1992, 13, 35-41.
20. Davis, M., Hitchcock, J.M., and Rosen, J.B. A neural analysis of fear
conditioning. In: Learning and memory: The behavioral and biological substrates.
I. Gormezano and E.A. Wasserman (Eds). Erlbaum Press: Hillsdale, N.J., 1992,
pp 153-182.
21. Davis, M. Analysis of aversive memories using the fear-potentiated startle
paradigm. In: Neuropsychology of Memory N. Butters & L. Squire (Eds),
Guilford Press: New York, 1992, pp. 470-484.
22. Davis, M. A Neural Systems Approach to the Study of the Amygdala, Fear and
Anxiety In: Experimental Approaches to Anxiety and Depression, M. Elliott
(Ed), John Wiley & Son, Inc.: New York, 1992, pp. 43-71.
23. Davis, M. Neural substrates of classical conditioning: The fear-potentiated
paradigm. In: The Encyclopedia of Learning and Memory (Larry Squire, Ed.).
MacMillan publishing Co.: New York, 1992, pp. 480-483.
24. Davis, M. and Egger, M.D. Habituation and sensitization in vertebrates:
Behavioral properties and neural substrates. In: The Encyclopedia of Learning
and Memory (Larry Squire, Ed.). MacMillan publishing Co.: New York, 1992,
pp. 237-241
25. Charney, D.S., Deutch, A Y., Krystal, J.H., Southwick, S.M. and Davis, M.
Psychobiological mechanisms of post-traumatic stress disorder. Archives of
General Psychiatry, 1993, 50, 294-305.
26. Davis, M. Pharmacological analysis of fear-potentiated startle. Brazilian Journal
of Medical and Biological Research, 1993, 26, 235-260.
27. Davis, M., Falls, W.A., Campeau, S. and Kim, M. Fear-potentiated startle: A
neural and pharmacological analysis. Behavioural Brain Research, 1993, 58, 175178.
28. Bremner, J.D., Davis, M., Southwick, S.M., Krystal, J.H., and Charney, D.S.
Neurobiology of posttraumatic stress disorder. In: Posttraumatic stress disorder:
A clinical review. R.S. Pynoos (Ed), Sidran Press: Lutherville, Md., 1994, pp.
43-64.
29. Davis, M. The role of the amygdala in emotional learning. In: International
Review of Neurobiology, 34, Academic Press: New York, 1994, pp. 255-266.
30. Davis, M. Rainnie, D. and Cassell, M. Neurotransmission in the rat amygdala
related to fear and anxiety. Trends in Neuroscience, 1994, 17, 208-214.
31. Davis, M., Campeau, S., Kim, M. and Falls, W.A. Neural systems of emotion:
The amygdala's role in fear and anxiety. In: Brain and Memory: Modulation and
23
Mediation of Neuroplasticity , (J. McGaugh,N.M. Weinberger, and G. Lynch,
Eds), Oxford University Press: New York, 1995, pp. 3-40.
32. Morris, R. G. M. and Davis, M. The role of NMDA receptors in learning and
memory, (Second Edition). In: The NMDA Receptor, (J.C. Watkins and G.L.
Collingridge, Eds), Oxford University Press: Oxford, 1994, pp. 340-375.
33. Davis, M. Fear-potentiated startle in the study of animal and human emotion. In:
Emotion: Interdisciplinary Perspectives, (R. Kavanaugh, B. Zimmerberg, B. Fein,
S. Eds), Lawrence Erlbaum Associates Inc.: Hillsdale, N.J., 1996, pp.61-90.
34. Falls, W.A. and Davis, M. Behavioral and physiological analysis of fear
inhibition: Extinction and conditioned inhibition. In: Neurobiological and
Clinical Consequences of Stress: From Normal Adaptation to PTSD. (M.J.
Friedman, D.S. Charney & A.Y. Deutch, Eds), Lippincott-Raven Publishers:
Philadelphia, 1995, p. 177-202.
35. Davis, M. Differential roles of the amygdala and bed nucleus of the stria
terminalis in conditioned fear and startle enhanced by corticotropin releasing
hormone. In: Perception, Memory and Emotion: Frontiers in Neuroscience, T.
Ono, B.L. McNaughton, S. Molotchnikoff, E.T. Rolls and H. Nishijo (Eds), 1996,
Elsevier, Ltd.: Oxford.p. 525-548.
36. Davis M, Walker DL, Lee Y: Roles of the amygdala and bed nucleus of the stria
terminalis in fear and anxiety measured with the acoustic startle reflex: Possible
relevance to PTSD. Annals of the New York Academy of Sciences.,
Psychobiology of Posttraumatic Stress Disorder, Vol. 821, The New York
Academy of Sciences, New York, New York, 1997, PP. 305-331.
37. Davis, M. The neurophysiological basis of acoustic startle modulation: Research
on fear motivation and sensory gating. In: Attention and Orienting; Sensory and
Motivational Processes, (P.J. Lang, R.F. Simons & M. T. Balaban, Eds.),
Lawrence Erlbaum, Associates: Hillsdale, N.J., 1997, pp. 69-96.
38. Davis, M. Neurobiology of fear responses: The role of the amygdala. Journal of
Neuropsychiatry and Clinical Neurosciences. 1997, 9. 382-402.
39. Walker, D.L., Cassella, J.V. Lee, Y., deLima, T.C.M., and Davis, M. Opposing
roles of the amygdala and dorsolateral periaqueductal gray in fear-potentiated
startle. Neuroscience and Biobehavioral Reviews, 1997, 21, 743-753.
40. Davis, M., Walker, D. L.and Lee, Y. Amygdala and bed nucleus of the stria
terminalis: Differential roles in fear and anxiety measured with the acoustic
startle reflex. Philosophical Transactions of The Royal Society, London:
Biological Sciences, 1997, 352, 1675-1687.
41. McNish, K.A., Gewirtz, J.C. and Davis, M. Reply to “The startled seahorse: is
the hippocampus necessary for contextual fear conditioning?”. Trends in
Cognitive Sciences, 1998, 2, 42-43.
42. Davis, M. Are different parts of the extended amygdala involved in fear versus
anxiety. Biological Psychiatry, 44, 1998, 1239-1247.
43. Fox, K., Bienenstock, E., Bonhoeffer, T., Byrne, J.H. Davis, M., Fregnac, Y.,
Gierer, A., Hubener, M., Mauk, M.D., Shatz, C.J. and Stryker, M. P. To what
extent are activity-dependent processes common to development and learning?
In: Mechanistic Relationships Between Development and Learning. T.J. Carew,
24
R. Menzel and C.J. Shatz (Eds). Dahlem Workshop Reports, John Wiley and
Sons, Chicester, England, 1998, p. 163-188.
44. Davis, M. and Lee, Y. Fear and anxiety: Possible roles of the amygdala and bed
nucleus of the stria terminalis. In: Cognition and Emotion, R. Davidson (ed),
Psychology Press, 1997, 11, pp. 277-306.
45. Davis, M. Anatomic and physiologic substrates of emotion in a animal model, J.
Clin. Neurophysiol. 15, 1998, 378-87.
46. Davis, M. and Lee, Y. Neurophysiology and neuropharmacology of startle and its
affective modification. In: Startle modification: Implication for Neuroscience,
cognitive science, and clinical science. M. Dawson, A. Schell and A. Bohmelt
(Eds). Cambridge University Press, 1999, pp. 95-113.
47. Gewirtz, J. C., and Davis, M. Beyond attention: The role of amygdala NMDA
receptors in fear conditioning (A commentary on Shors and Matzel). Behavioral
Brain Sciences, 1997, 20, 618-619.
48. Davis, M. and Shi, C-J. The extended amygdala: Are the central nucleus of the amygdala and
the bed nucleus of the stria terminalis differentially involved in fear vs. anxiety? In J. F. McGinty
(Ed.), Annals of the New York Academy of Sciences. 1999, 877, pp. 281-291.
49. Davis, M. Are different parts of the extended amygdala involved in fear versus anxiety.
Biological Psychiatry, 44, 1998, 1239-1247.
50. McDonald, A. J., Shamman-Lagnado, S. J., Shi, C. J., & Davis, M. Cortical afferents to the
extended amygdala. In J. F. McGinty (Ed.), Annals of the New York Academy of Sciences. 877,
New York: Annals of the New York Academy of Sciences, 1999, pp. 309-338.
51. Davis, M. and Shi, C-J. The amygdala. Current Biology, 2000, 10, R131.
52. Gewirtz, J. C., McNish, K.A. and Davis, M. Is the hippocampus necessary for
contextual fear conditioning? Behavioral Brain Research, 2000, 110, 83-95
53. Davis, M. Neural circuits of anxiety and fear (1999).. In: Neurobiological
foundation of mental illness. D. Charney, E. Nestler and B. Bunney (Eds).
Oxford University Press, 1999, 463-474
54. Davis, M. The role of the amygdala in conditioned and unconditioned fear and
anxiety. In J. P. Aggleton (Ed.), The Amygdala, Volume 2, Oxford, United
Kingdom: Oxford University Press, 2000, p. 213-288
55. Lang, P. J., Davis, M., & Ohman, A. Fear and anxiety: animal models and
human cognitive psychophysiology. Journal of Affective Disorders, 2001, 61, 137
- 159.
56. Davis, M. Falls, W. A. Gewirtz, J. Neural systems involved in fear inhibition:
Extinction and conditioned inhibition. In: Contemporary Issues in Modeling
Psychopathology, M. Myslobodsky and I. Weiner (Eds), Kluwer Academic
Publishers: London. 2000, p. 113-142.
57. Gewirtz, J.C. and Davis, M. Using Pavlovian “higher-order” conditioning
paradigms to investigate the neural substrates of emotional learning and memory.
Learning and Memory, 2000, 7, 257-266.
58. Ladd, C.O., Plotsky P.M., and Davis M. 2000, Startle response. In: Encyclopedia
of Stress (Fink , G. - Ed) , vol. 3. Academic Press, San Diego, pp. 486-495.
59. Davis, M. and Whalen, P. The amygdala: Vigilance and Emotion. Molecular
Psychiatry, 2001, 6, 13-34
25
60. Davis, M. Fear potentiated startle. In: Current Protocols in Neuroscience. 2001,
John Wiley and Sons, 8-11A, 1-11
61. Walker, D. L., & Davis, M. (2001). The role of glutamate receptors within the
amygdala in fear learning and fear-potentiated startle. In : D. D. S. a. E. A. C. E.
L. Turski (Ed.), Excitatory Amino Acids: Ten Years Later (pp. 109-127).
Amsterdam: IOS Press.
62. Shekhar, A., McCann, U.D., Meaney, M.J., Blanchard, D.C., Davis, M., Frey,
K.A., Liberzon, I., Overall, K.L., Shear, M.K., Tecott, L.H., Winsky, L.:
Summary of a National Institute of Mental Health workshop: developing animal
models of anxiety disorders. 2001, Psychopharmacology, 157, 327-339
63. Davis, M. Fear: Potentiation of startle. In: Encyclopedia of the Social &
Behavioral Sciences. N. J. Smelser and Paul B. Baltes (editors) 2001
International Pergamon, Oxford, pp. 5524-5528.
64. Davis, M. Startle, fear potentiation. In: Encyclopedia of Psychology and
Neuroscience, W.E. Craighead and C.B. Nemeroff (Eds). (2001) John Wiley and
Sons,
65. Davis, M. Neural Circuitry of Anxiety and Stress Disorders. In Generation of
Progress, Vol., 5. Philadelphia: Lippincott, Williams & Wilkins, (2002) pp. 931952.
66. Davis, M. Role of NMDA receptors and MAP kinase in the amygdala in extinction of fear:
clinical implications for exposure therapy. European Journal of Neuroscience, 2002, 16,
395-399.
67. Myers, K.M. and Davis, M. Behavioral and Neural Analysis of Extinction: A
Review. Neuron, 2002, 36, 567-584.
68. Myers, K.M. and Davis, M. Systems-level reconsolidation: Re-engagement of the
hippocampus with memory reactivation. Neuron (Preview), 2002, 36, 340-343.
69. Davis, M. and Myers, K.M. The role of glutamate and gamma-aminobutyric acid
in fear extinction: clinical implications for exposure therapy, Biological
Psychiatry, 2002, 52, 998-1007.
70. Davis, M. Neural Substrates of Classical Conditioning: Fear-Potentiated Startle.
Encyclopedia of Learning and Memory, Second Edition (J. Byrne, Ed). New
York: MacMillian: Thompson& Gale, 2002, pp. 463-466.
71. Ressler K and Davis M (2003) Genetics of Childhood Disorders: L. Learning
and Memory, Part 3: Fear Conditioning. J. Am. Acad. Child Adolesc. Psych. 42,
612-615.
72. Davis M, Walker DL, Myers KM (2003) The role of the amygdala in fear
extinction measured with potentiated startle. In: The amygdala in brain function:
Basic and Clinical Approaches (Shinnick-Gallacher P, Pitkanen A, Skekhar A,
Cahill L, eds), pp 218-232. New York: New York Academy of Sciences.
73. Davis, M. (2002) Role of NMDA receptors and MAP kinase in the amygdala in
extinction of fear: Clinical implications for exposure therapy. European Journal
of Neuroscience. 16. 395-398.,
74. Walker, D. L., Toufexis, D. J., & Davis, M. (2003). Role of the bed nucleus of the
stria terminalis versus the amygdala in fear, stress, and anxiety. European Journal
of Pharmacology, 463, 199-216
26
75. Rothbaum, B.O. and Davis, M. (2003) Applying learning principles to the
treatment of post-trauma reactions. New York Academy of Science, 1008, 112121.
76. Davis, M. (2003). Neural Substrates of Classical Conditioning: Fear-Potentiated
Startle. Learning and Memory, second edition, John H. Byrne, editor, Macmillian
, New York, pp 463-466.
77. Davis, M. and Lang, P.J. (2003) Emotion: Integration of animal and human data
and theory. In: Handbook of Psychology: Biological Psychology, Vol. 3 Wiley
Publishers, pp. 405-441.
78. Davis, M. Neural circuits of anxiety and fear. In: Neurobiology of mental illness.
(2004). D. Charney, E. Nestler (Eds). Oxford University Press, pp. 584-604.
79. Walker DL, M Davis (2004). Are fear memories made and maintained by the
same NMDA receptor-dependent mechanisms? Neuron, 41:680-682.
80. Rattiner, L., Davis, M. and Ressler, K. (2005) Brain-derived neurotrophic factor
in amygdala dependent learning. The Neuroscientist, 11, 323-333.
81. Davis, M., Myers, K.M., Ressler, K. J., Rothbaum, B.0 (2005). Facilitation of
Extinction by D-cycloserine: Implications for Psychotherapy. Current Directions
in Psychological Science, 14, 214-219
82. Davis, M. D-cycloserine as an adjunct to psychotherapy: Rational and
preliminary clinical results (2005). Cerebrum, 7, 47-58.
83. Davis, M., Myers, K. M., Chhatwal, J. and Ressler, K.J. (2006). Pharmacological treatments that
facilitate extinction of fear: Relevance to psychotherapy NeuroRx. 3, 82–96
84. Davis, M., Ressler, K.J., Rothbaum, B.O. and Richardson, R (2006). Effects of Dcycloserine on extinction: Translation from preclinical to clinical work.
Biological Psychiatry, 60:369–375
85. Toufexis, D., Myers, K.M. and Davis, M. (2006). The effect of gonadal
hormones and gender on anxiety and emotional learning, Hormones and
Behavior, 50, 539-549.
86. Davis, M., Barad, M., Otto, M., and Southwick, S. (2006). Combining
pharmacotherapy with cognitive behavioral therapy: Traditional and new
approaches. Journal of Traumatic Stress, 19, 571-582.
87. Davis, M. (2006). Neural systems involved in fear and anxiety based on the fear-potentiated
startle test. American Psychologist, 61, 741-756
88. Lang, P. and Davis, M. (2006) Emotion, motivation, and the brain: Reflex
foundations in animal and human research. Progress in Brain Research,
2006,156, 3-29.
89. Ressler KJ, Davis M, and Rothbaum (2006). Pharmacological enhancement of learning in
exposure therapy. In: The Comprehensive Handbook of Exposure Therapies. Richard DCS,
Lauterbach D (Eds.), Elsevier Academic Press, Burlington, MA, pp. 335-346, 2006.
90. Toufexis, D. J., Myers, K. M., & Davis, M. (2006). The effect of gonadal hormones and
gender on anxiety and emotional learning. Hormones and Behavior, 50, 539-549.
91. Myers, K. M., & Davis, M. (2007). Mechanisms of fear extinction. Mol Psychiatry. 12,
120-50
92. Davis, M. (2007) Forgetting: Once again it all about representations. In Science of Memory:
Concepts. H.L. Roediger III, Y. Dudai, S.M. Fitzpatrick (Eds); Oxford University Press,
New York, New York. pp. 317-319.
27
93. Davis, M. (2007) Neural systems involved in fear and anxiety based on the fear-potentiated
startle test. In: Neurobiology of Learning and Memory, Second Edition, R. P. Kesner and J.
L. Martinez (Eds); Elsevier, Ltd. Oxford, pp. 381-418.
94. Davis, M., Antoniadis, E.A., Amaral, D.G., Winslow, J.T. (2008) Acoustic startle
reflex in rhesus monkeys: A review. Neuroscience Reviews, 19, 71-186.
95. Walker, D.L. and Davis, M. (2008) Role of the extended amygdala in shortduration versus sustainedfear: a tribute to Dr. Lennart Heimer. Brain Structure
and Function 213, 29-42.
96. Davis M and Myers K M (2009) Pharmacology of Fear Extinction. In: Squire LR
(ed.) New Encyclopedia of Neuroscience, volume 7, pp. 595-600. Oxford:
Academic Press.
97. Myers, K.M., Toufexis, D.J., Winslow, J.T., Jovanovic, T., Norrholm, S.D., .
Duncan, E.J., and Davis, M. (2009) Measurement of fear inhibition in rats,
monkeys, and humans with or without PTSD using the AX+, BX- paradigm. In:
The Human Amygdala: P.Whalen & E. Phelps, (Eds.), pp. 61-81. Guildford Press,
New York, NY
98. Davis, M., Walker, D. L., Miles, L., & Grillon, C. (2009) Phasic vs
Sustained Fear in Rats and Humans: Role of the Extended Amygdala
in Fear vs Anxiety. Neuropsychopharmacology, 35, 105-35
99. Walker, D. L., Miles, L., and Davis, M. (2009) Selective participation
of the bed nucleus of the stria terminalis and CRF in sustained anxietylike versus phasic fear-like responses. Progress in NeuroPsychopharmacology and Biological Psychiatry, 33, 1291-1308.
100.
Publications in Press
1. Myers, K.M. and Davis, M. Extinction of fear: Animal studies to clinical
interventions. In: Encyclopedia of Fear and Anxiety, Blanchard, R. and
Blanchard, C. (Ed)
2. Norrholm, S.D., Jovanovic, T., Rothbaum, B.O. Davis, M.,
Hasenkamp, W., Crowe, C. Duncan, E., Leimbach, L., Skelton, K.,
Bradley, B (2010). The optimization of research and clinical
applications for combat-related posttraumatic stress disorder (PTSD):
Progress through modern translational methodologies. In. Military
Psychiatry: New Developments. Nova Science Publishers, Hauppage,
NY
3. Davis, M. Facilitation of extinction and psychotherapy by D-cycloserine. Journal
of Psychology
4. Glover, E., Ressler, K. J. and Davis, M. Effects of rapamycin on context vs. cue
conditioning using the fear-potentiated startle paradigm. Learning and Memory
(In press).
5. Myers, K.M., Carlezon, W. A. and Davis, M. (2010) Glutamate receptors in
extinction and extinction-based therapies for psychiatric illness.
Neuropsychopharmacology (ePub)
28
Papers submitted
1. Sink K.S., Walker D.L., Yang Y., Davis M. Calcitonin gene-related peptide in the
bed nucleus of the stria terminalis produces an anxiety-like pattern of behavior
and increases neural activation in anxiety-related structures (in revision).
2. Parson, R.G. and Davis, M. Temporary, but not long term, disruption of fear
potentiated startle following PKMζ inhibition in the amygdala
3. Kazama, A., Heuer, E., Davis, M. and Bachevalier, J. Fear learning, conditioned
inhibition, and extinction in adult macaques: I - Effects of neonatal amygdala
lesions
4. Davis, M., Bowser, M.E., McDevitt, J. and Walker, D.L. Facilitation of fear
extinction by D-cycloserine given prior to sleep