The Medical School. 11th Annual Medical School Research Meeting 15th – 16th June 2015 PROGRAMME Monday 15th June 2015 Venue: Octagon Centre 09:00-10:00 Poster presenters to hang posters, stand holders and “New Staff” exhibition to set up. Venue: Student Union Auditorium 10:00-11:00 Plenary Lecture - “Communicating Science” Professor Allan Pacey (Head of Unit, Reproductive and Developmental Medicine) Venue: Octagon Centre 11:00 -12:00 Hot Research Topics - Poster Technique Tours Organised by Medicine, Dentistry and Health Research Staff Association (MDHRSA) 12:00-13:00 Lunch with the Speakers (for poster tour participants, organisers, speakers and stand hosts only) 13:00 – 15:00 Achieving a successful career beyond University - Breakout session 1 NHS 13:00 – Dr Hazel Wilkinson – Operations Manager, UK NEQAS for Immunology 13:30 – Miss Sarah Hawtree – Trainee Healthcare Scientist 14:00 – Dr Keith Hunter – Reader in Oral & Maxillofacial Pathology, Academic Director Oral & Dental, UoS 14:30 – Mrs Samantha Walmsley – Research Support & Management, Clinical Research Network Academia 13:00 – Dr Neil Harris – Research Strategy Manager, Research & Innovation Services, UoS 13:30 – Professor Simon Foster – Director of Krebs Institute, UoS 14:00 – Dr Rosemary Gault – European Project Coordinator, Advanced Manufacturing Park, UoS 14:30 – Dr Isobel Gowers – Senior Lecturer in Animal Therapy, Writtle College Industry 13:00 – Dr Samantha Decombel – Chief Operating Officer & co-founder MuscleGenes.com 13:30 – Ms Mariam Zare – General Manager – Sales & Marketing, Advanced Medical Solutions 14:00 – Dr Kirstie Bennett – Senior Pharmacologist, Heptares Therapeutics Ltd 14:30 – Dr James Lynch – Clinical Pharmacology Scientist, Astra Zeneca (Rooms to be confirmed) 15:00 – 15:30 Refreshment break 15:30 – 16:30 Achieving a successful career beyond University - Breakout session 2 NHS 15:30 – Dr Richard Battle – Senior Healthcare Scientist, National Histocompatibility and Immunogenetics Lab Manager – Scottish National Blood Transfusion Service 16:00 – Dr Cher Cartwright – Senior Information Analyst, Health and Social Care Information Centre Academia 15:30 – Dr Alison Graham – Teaching Fellow, School of Biology, Newcastle University 16:00 – Dr Laura Ferraiuolo – Marie Curie Research Fellow, Neuroscience, UoS Industry 15:30 – Dr Sam Whitehouse – Chief Operating Officer, QuantuMDx 16:00 – Dr Lee Allen – Purification Research and Technology Lead, Lonza Pharma / Biotech (Rooms to be confirmed) Venue: Octagon Centre 16:30-17:30 Wine reception and Poster Bay Tours Tuesday 16th June 2015 Venue: Student Union Auditorium 08:40 Registration for Oral and Poster Presenters 08:55 Welcome and introduction Professor Tony Weetman – Pro-Vice Chancellor, Medicine, Dentistry & Health Session 1: Chaired by Professor Paul Ince – Head of Department, Neuroscience Co-chaired by Dr Rachel Waller, MDHRSA 09:00 Dr Iwan Evans [Infection & Immunity] Sir Henry Dale Fellow Draper/CED-1 mediates an ancient damage response to control inflammatory blood cell migration in vivo 09:15 Dr Pallai Shillo [Human Metabolism] PhD Student – 2nd Year Low Vitamin D Levels in Patients with Painful Diabetic Peripheral Neuropathy: A Potential Role in Pathogenesis? 09:30 Ms Charlotte Rowan [Oncology] PhD Student – 2nd Year A subset of peripheral blood monocytes exhibit an M2-skewed phenotype after doxorubicin treatment: are these the precursors of relapse-promoting M2 TAMs? 09:45 Mr Simeon Mihayloy [Neuroscience] PhD Student – 2nd Year Investigating the RNA-Binding Activity of PGC-1[alpha] in Neurodegeneration and Ageing 10:00 Mrs Emma MacInnes [Oncology] PhD Student – 2nd Year MRI and mammographic screening in young women at increased familial breast cancer risk 10:15 Dr Paul Morris [Cardiovascular Science] PhD Student – 3rd Year The Development and Validation of an In Silico Model of Coronary Arterial Physiology for Diagnostic Use 10:30 – 11:00 COFFEE / TEA BREAK (OCTAGON CENTRE) Session 2: Chaired by Professor Sheila Francis – Head of Department, Cardiovascular Science Co-chaired by Mr Matthew Sellwood, MPGS 11:00 Dr Esther Hobson [Neuroscience] PhD Student – 2nd Year Facilitating access to specialist care for patients and carers affected by Motor Neurone Disease using telehealth 11:15 Mr Joshua Griffiths [Infection & Immunity] BMedSci Student Role of specific pro resolving mediators in inflammation resolution and regeneration in an in vivo zebrafish model 11:30 Dr Magdalena Adamczyk [Human Metabolism] Arthritis Research UK Foundation Fellow Are P2X7R-/- mice protected from IL-1β-mediated TG2 upregulation and rapid release? 11:45 Dr Alex Rothman [Cardiovascular Science] MRC Clinical Research Training Fellow miR140-5p is a key pathological mediator of pulmonary arterial hypertension and modulates BMP signalling through SMURF1 Keynote Speaker Introduction - Professor Nicola Brown – Deputy Head of Department, Oncology 12:00 KEYNOTE LECTURE: “NEUTROPHIL-VESSEL WALL INTERACTIONS IN VIVO: MODE, MECHANISMS AND PATHOGENESIS” Professor Sussan Nourshargh, Professor of Microvascular Pharmacology, Barts and the London Medical School 13:00 – 15:00 LUNCH, POSTER VIEWING & NETWORKING – OCTAGON CENTRE 13:00-15:00 trade stands 13:30-14:30 2nd Year postgraduate poster presentation assessment 13:30-14:00 viewing of even numbered posters 14:00-14:30 viewing of odd numbered posters 14:30-15:00 New staff seeking collaboration exhibition Session 3: Chaired by Professor Tim Skerry – Head of Department, Human Metabolism Co-chaired by Dr Claire Bradshaw, MDHRSA 15:00 Dr Clare Howarth [Psychology] Vice Chancellor’s Advanced Fellow Mechanisms of neurovascular coupling: imaging from cell level to whole brain 15:15 Mr Felix Horn [Cardiovascular Science] PhD Student – 4th Year Quantitative 3D lung function measurement -results from patient studies and predictive modelling of global multiple breath washout 15:30 Dr Victoria Stern [Human Metabolism] PhD Student – 2nd Year Assessing the Risk of Spontaneous Premature Birth by Electrical Impedance Spectroscopy of the Cervix: The ECCLIPPx Study 15:45 Dr Fiona Taylor [Oncology] PhD Student – 2nd Year Non-invasive molecular profiling of circulating cell-free DNA in lung cancer 16:00 Dr Jonathan Cooper-Knock [Neuroscience] PhD Student – 3rd Year Antisense and sense RNA foci derived from hexanucleotide repeat expansions of C9ORF72 have similar protein-interactions but distinct neuronal expression patterns 16:15 Dr Andrew Street [Infection & Immunity] Senior Research Fellow Polycystin-1 trafficking is regulated by cAMP dependent phosphorylation of the PLAT domain 16:30 Presentation of Prizes for Oral Presentations & Posters Professor Christopher Newman – Faculty Director for Research & Innovation 16:45 Closing Remarks by Professor Sussan Nourshargh & Professor Sherif El-Khamisy